Autism is both a medical condition that gives rise to disability and an example of human variation that is characterised by neurological and cognitive differences. The goal of evidence-based intervention and support is to alleviate distress, improve adaptation, and promote wellbeing. Support should be collaborative, with autistic individuals, families, and service providers taking a shared decision-making approach to maximise the individual's potential, minimise barriers, and optimise the person–environment...
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In their Series article in The Lancet Neurology,1 Meng-Chuan Lai and colleagues provide an important new perspective on how autism can be understood, and an evidence-informed account of existing approaches to intervention and support for autistic people across the lifespan. They emphasise that the evidence base is weak, if gradually improving, and propose a tripartite support framework to secure the wellbeing of autistic individuals. Intriguingly, Lai and colleagues seek to align medical and neurodiversity...
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We read the excellent Comment by Wenhua Liang and colleagues1 in The Lancet Oncology with great interest. Of 1590 cases with confirmed coronavirus disease 2019 (COVID-19), 18 patients had a history of cancer. The authors concluded that patients with cancer had a higher risk of COVID-19 and with a poorer prognosis than those without cancer.
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The outbreak of coronavirus disease 2019 (COVID-19) is of international concern. We appreciated the Comment from Wenhua Liang and colleagues1 published in The Lancet Oncology on Feb 14, 2020, which, to the best of our knowledge, was the first to focus on COVID-19 infection in patients with cancer.
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Little is known on the systemic effects of oral and maxillofacial surgery on the hemostatic balance including the biochemical effects of tranexamic acid (TXA) on fibrin clot lysis. The study aimed to investigate the effect of orthognathic surgery on fibrin lysability, fibrin structure and D-Dimer and to evaluate the effect of TXA on these fibrinolytic measures.
Tue Mar 03, 2020 02:00
The use of titanium-based implants in mandibular condyle fractures may require implant removal because of screw penetration through the condylar surface. Biodegradable implants may avoid a second operation for implant removal and its associated possible complications. In this work, we investigated the clinical and radiological outcome of osteosynthesis of mandibular condyle fractures with biodegradable magnesium-based compression screws.
Tue Mar 03, 2020 02:00
Stem Cells and Development, Volume 29, Issue 5, Page 263-265, March 1, 2020.
Thu Feb 27, 2020 10:00
The objectives of this study were to obtain patient evaluations of the content, structure, and delivery modality of Meaning-Centered Pain Coping Skills Training (MCPC), a novel psychosocial intervention for patients with advanced cancer and pain. MCPC aims to help patients connect with valued sources of meaning in their lives (e.g., family relationships), while providing training in evidence-based cognitive and behavioral skills (e.g., guided imagery) to reduce pain. METHODS: Semi-structured...
Mon Mar 02, 2020 00:00
We describe the adaptation of MCP-WTC and the application of this intervention to meet the unique needs of those exposed to the terrorist attacks of September 11, 2001 (9/11), participated in the rescue, recovery, and clean-up effort at Ground Zero, and were diagnosed with WTC-related cancer. We highlight the novel aspects of this intervention which have been designed to facilitate meaning-making in the context of the patient's response to 9/11 and subsequent diagnosis of cancer. SIGNIFICANCE...
Mon Mar 02, 2020 00:00
How are medical societies reacting to the threat of coronavirus? Medscape Medical News surveys the landscape.Medscape Medical News (Source: Medscape Allergy Headlines)
Tue Mar 03, 2020 20:12
According to new information from a Chinese patient cohort, the fatality rate may be'considerably less than 1%,'instead of the 2% previously reported, write Anthony Fauci, MD, and colleagues.Medscape Medical News (Source: Medscape Allergy Headlines)
Tue Mar 03, 2020 02:26
The research shows the potential benefit of a machine learning model in assessing functional connectivity to understand clinical impairment in MS.Medscape Medical News (Source: Medscape Allergy Headlines)
Mon Mar 02, 2020 21:53
Interim blinded findings of the VISIONARY-MS trial suggest some overall improvement in visual impairment in MS patients with a potentially remyelinating agent or placebo.Medscape Medical News (Source: Medscape Allergy Headlines)
Mon Mar 02, 2020 20:05
To describe the burden of esophageal dilatations in patients following esophageal atresia (EA) repair.
Tue Mar 03, 2020 02:00
The pectus bar removal procedure is often considered a simple, straightforward surgery with a low incidence of complications. However, life-threatening bleeding complications have been reported requiring major measures for hemostatic control. Our objective is to share a simple maneuver that our group has systematically included in the bar removal procedure to facilitate bleeding control in case hemorrhage occurs.
Tue Mar 03, 2020 02:00
Recent political events had led some to ask, "Is it moral to be a billionaire?" Let's talk about wealth, merit, and compassion.
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A new study surveys the modern landscape of online dating.
Tue Mar 03, 2020 20:32
How are you coping with concerns over the coronavirus? Here are a few key strategies to implement.
Tue Mar 03, 2020 16:29
There are many effective strategies for resolving alcohol or drug addiction.
Tue Mar 03, 2020 14:50
The new guidelines provide additional guidance for healthcare providers to better recognize and diagnose breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). (Source: CancerNetwork)
Tue Mar 03, 2020 06:00
Kura Oncology ’s leading drug candidate, tipifarnib, was granted fast track designation by the FDA to treat adults of T-cell lymphomas. (Source: CancerNetwork)
Tue Mar 03, 2020 06:00
A study, published in Nature Cancer, demonstrates the quick and evolving revolutions of resistance mechanisms in small cell lung cancer. (Source: CancerNetwork)
Tue Mar 03, 2020 06:00
ConclusionsRT rates for older women with early-stage breast cancer are declining with patient-level variation based on factors related to life expectancy and locoregional recurrence. Facility-level variation suggests opportunities to improve care delivery by focusing on barriers to de-implementation ofroutine use of RT. (Source: Breast Cancer Research and Treatment)
Tue Mar 03, 2020 00:00
ConclusionNo association was observed between a reduced BMD and DRFS. Neither did we observe an impact of bisphosphonates on DRFS. (Source: Breast Cancer Research and Treatment)
Mon Mar 02, 2020 00:00
ConclusionsHER2-ccdPAs might be useful for cell-based gene therapy. This system could be a platform for various antibody therapies. (Source: Breast Cancer Research and Treatment)
Mon Mar 02, 2020 00:00
Abstract Objective To translate and cross‐cultural adapt the Craniofacial Pain and Disability Inventory (CF‐PDI) into Chinese and, to evaluate measurement properties of the web‐based version of the CF‐PDI. Methods The Chinese version (CF‐PDI/C) was first produced according the guidelines. Then, the web‐based version of CF‐PDI/C (eCF‐PDI/C) was developed by our team and a third‐party survey provider. The eCF‐PDI/C was distributed to patients with painful TMD with or without headache...
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Title: Pick Summer Camps Carefully When Your Kid Has Allergies, AsthmaCategory: Health NewsCreated: 2/29/2020 12:00:00 AMLast Editorial Review: 3/2/2020 12:00:00 AM (Source: MedicineNet Allergies General)
Mon Mar 02, 2020 08:00
Title: Crafting With Dry Pasta, Play-Doh Safe for Kids With Gluten Sensitivity: StudyCategory: Health NewsCreated: 2/4/2020 12:00:00 AMLast Editorial Review: 2/5/2020 12:00:00 AM (Source: MedicineNet Allergies General)
Wed Feb 05, 2020 08:00
Chondroblastoma (CB) is a rare locally aggressive bone tumor that commonly occurs in the epiphysis or apophysis of long bones. Although surgical treatment of CB carries potential risk for physeal or articular ... (Source: World Journal of Surgical Oncology)
Mon Mar 02, 2020 01:00
Primary intraosseous carcinoma (PIOC), NOS is an odontogenic carcinoma with unknown etiology. Its diagnosis may be used when central jaw carcinoma cannot be categorized as any other type of carcinoma. Further ... (Source: World Journal of Surgical Oncology)
Sat Feb 29, 2020 01:00
This study aims to examine the clinical effect of non-vascularized fibular graft on patients wit... (Source: World Journal of Surgical Oncology)
Sat Feb 29, 2020 01:00
Total gastrectomy (TG) is a widely accepted procedure for treating gastric stump cancer (GSC). However, subtotal gastrectomy (SG) would benefit elective patients with GSC. The aim of this study was to clarify ... (Source: World Journal of Surgical Oncology)
Thu Feb 27, 2020 01:00
Whether video-assisted thoracoscopic surgery (VATS) segmentectomy and VATS lobectomy provide similar perioperative and oncological outcomes in stage I non –small cell lung cancer (NSCLC) is still controversial. (Source: World Journal of Surgical Oncology)
Thu Feb 27, 2020 01:00
ConclusionA surgical protocol involving bilateral FESS along with debridement of visibly affected areas and antifungal therapy avoids repeated surgery in patients with AIFS with no change in outcomes. The absence of clinicoradiological involvement of the paranasal sinuses does not preclude the presence of invasive fungal disease in these sinuses. (Source: European Archives of Oto-Rhino-Laryngology)
Tue Mar 03, 2020 00:00
AbstractAlthough the E3 ubiquitin ligase Zinc and ring finger 3 (ZNRF3) negatively regulates the Wnt signaling pathway, its function in rheumatoid arthritis (RA) is elusive. Here, the effects and the mechanism of ZNRF3 on a mouse model of collagen-induced arthritis (CIA) and human fibroblast-like synoviocytes (FLS) obtained from RA patients were determined. Our results showed that ZNRF3 was highly expressed in tissues and FLSs compared to trauma patients. Lentivirus-mediated silencing of ZNRF3 induced...
Tue Mar 03, 2020 00:00
AbstractSodium butyrate (NaBu), a histone deacetylase inhibitor, has shown to exert beneficial actions attenuating inflammation in a number of intestinal and extra-intestinal diseases. However, the effects of NaBu on persistent inflammatory processes as in a response to implantation of foreign material have not been investigated. Synthetic matrix of polyether-polyurethane sponge was implanted in mice ’s subcutaneous layer of the dorsal region, and the animals were treated daily with oral administration...
Tue Mar 03, 2020 00:00
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