Sun Mar 15, 2020 07:29
Publication date: January 2020Source: Gene Expression Patterns, Volume 35Author(s):
Mon Mar 16, 2020 14:34
Publication date: January 2020Source: Gene Expression Patterns, Volume 35Author(s):
Mon Mar 16, 2020 14:34
School feeding programs are beneficial for the physical, mental, and psychosocial development of school-age children and adolescents, particularly those in low- and middle-income countries (LMICs). While schoo...
Mon Mar 16, 2020 02:00
Abstract Objectives This study aimed to investigate the relationship between aging and tooth loss on masseter muscle quantity and quality. Materials and methods This cross-sectional study was conducted among 112 participants (in their 20s to 90s) who were independent in activities of daily living and were able to follow verbal commands. Exclusion criteria...
Mon Mar 16, 2020 02:00
Abstract The interplay between lncRNAs and miRNAs was reported to be associated with cerebral ischemia reperfusion injury (CIRI). Besides, the lncRNA ZFAS1 was significantly downregulated in patients with ischemic stroke. However, the exact biological role of ZFAS1 and its mechanism in CIRI remain to be elucidated. The current study was designed to explore the protective effects of ZFAS1 on neuronal injury, inflammation, oxidative stress,...
Mon Mar 16, 2020 02:00
Background Several studies have reported the association between gait and global cognitive function; however, there is no study explaining the age-specific gait characteristics of older women and association between those characteristics and global cognitive function by age-specific differences and gait speed modification. The aim of this study was to examine age-specific differences in gait characteristics and global cognitive function in older women as well as identify gait domains strongly associated...
Mon Mar 16, 2020 02:00
Atlantia is described as a new genus pertaining to the family Dendrophylliidae (Anthozoa, Scleractinia) based on specimens from Cape Verde, eastern Atlantic. This taxon was first recognized as Enallopsammia micranthus and later described as a new species, Tubastraea caboverdiana, which then changed the status of the genus Tubastraea as native to the Atlantic Ocean. Here, based on morphological and molecular analyses, we compare fresh material of T. caboverdiana to other dendrophylliid genera and...
Mon Mar 16, 2020 02:00
Background The aims of this systematic review and meta-analyses were to determine if there is a statistically reliable association between poor reading and poor self-concept, and if such an association is moderated by domain of self-concept, type of reading impairment, or contextual factors including age, gender, reading instruction, and school environment. Methodology We searched 10 key databases for published and unpublished...
Mon Mar 16, 2020 02:00
Xinjiang brown cattle have better meat quality than Kazakh cattle. Circular RNAs (circRNAs) are a type of RNA that can participate in the regulation of gene transcription. Whether circRNAs are differentially expressed in the longissimus dorsi between these two types of cattle and whether differentially expressed circRNAs regulate muscle formation and differentiation are still unknown. In this study, we established two RNA-seq libraries, each of which consisted of three samples. A total of 5,177 circRNAs...
Mon Mar 16, 2020 02:00
Background Leucojum aestivum L. is an important medicinal plant which produces Amaryllidaceae alkaloids, especially galanthamine and lycorine. Research is currently exploring the possibility of producing these alkaloids using biotechnological methods, including in vitro cultures. The biosynthesis of alkaloids may be affected by the types and concentrations of carbohydrate sources used in the medium. In the present investigation we performed such studies on in vitro cultures of L. aestivum with...
Mon Mar 16, 2020 02:00
Background Gliomas are the most prevalent type of intracranial tumors. NKCC1 is an important regulator in tumor cell volume. We noticed that abnormally high NKCC1 expression resulted in changes in the shape and adhesion of glioma cells. However, little is known about the role of NKCC1 in the epithelial-mesenchymal transition (EMT) of gliomas. This study aims to clarify the biological function of NKCC1 in glioblastoma multiforme (GBM) progression. ...
Mon Mar 16, 2020 02:00
Members of a society interact using a variety of social behaviors, giving rise to a multi-faceted and complex social life. For the study of animal behavior, quantifying this complexity is critical for understanding the impact of social life on animals’ health and fitness. Multilayer network approaches, where each interaction type represents a different layer of the social network, have the potential to better capture this complexity than single layer approaches. Calculating individuals’ centrality...
Mon Mar 16, 2020 02:00
Of the roughly 400 species of Perlidae in the world, most species are widely distributed in the northern hemisphere, but a few can be found in South Africa and South America. There are only five species in the genus Flavoperla of the family Perlidae in China. To gain a better understanding of the architecture and evolution of mitochondrial genome in Flavoperla, the entire mitochondrial genome (mitogenome) of a Chinese Flavoperla biocellata Chu, 1929 from family Perlidae (Insecta: Plecoptera) was...
Mon Mar 16, 2020 02:00
Purpose The aim of this study was to evaluate the feasibility of anterior pelvic ring fixation alone for treating lateral compression type 1 (LC-1) fractures with nondisplaced complete sacral fractures. Methods Patients with LC-1 type pelvic fractures with nondisplaced complete sacral fractures in the Xi’an Honghui Hospital were screened. Those who underwent surgical treatment for the anterior pelvic ring fractures and...
Mon Mar 16, 2020 02:00
To determine the Dysgonia stuposa mitochondrial genome (mitogenome) structure and to clarify its phylogenetic position, the entire mitogenome of D. stuposa was sequenced and annotated. The D. stuposa mitogenome is 15,721 bp in size and contains 37 genes (protein-coding genes, transfer RNA genes, ribosomal RNA genes) usually found in lepidopteran mitogenomes. The newly sequenced mitogenome contained some common features reported in other Erebidae species, e.g., an A+T biased nucleotide composition...
Mon Mar 16, 2020 02:00
Circular RNAs (circRNAs) are long noncoding RNAs that play a significant role in various biological processes, including embryonic development and stress responses. These regulatory molecules can modulate microRNA activity and are involved in different molecular pathways as indirect regulators of gene expression. Thousands of circRNAs have been described in diverse taxa due to the recent advances in high throughput sequencing technologies, which led to a huge variety of total RNA sequencing being...
Mon Mar 16, 2020 02:00
Multiple sclerosis (MS) is one of the most common neurological disabilities of the central nervous system. Immune-modulatory therapy with Interferon-β (IFN-β) is a commonly used first-line treatment to prevent MS patients from relapses. Nevertheless, a large proportion of MS patients on IFN-β therapy experience their first relapse within 2 years of treatment initiation. Feature selection, a machine learning strategy, is routinely used in the fields of bioinformatics and computational biology to determine...
Mon Mar 16, 2020 02:00
Natural antioxidants present in several medicinal plants are responsible for inhibiting the harmful effects of oxidative stress. These plants contain polyphenols and flavonoids that act as free radical scavengers and reduce oxidative stress and may be an alternative remedy to cure various harmful human diseases. This study aims to quantify the total phenolic and flavonoid contents (TPC and TFC) and antioxidant properties of methanol extracts of fruits, seeds, and bark of an important medicinal and...
Mon Mar 16, 2020 05:20
Abstract Adrenal insufficiency (AI) is an immune-related adverse event of immune checkpoint inhibitors and on occasion could be serious. There have been few reports of clinical information regarding AI associated with anti-programmed cell death protein-1 (anti-PD-1) antibody in non-small-cell lung cancer (NSCLC) patients. Patients with advanced NSCLC treated with anti-PD-1 antibodies between December 2015 and October 2017 were identified from the medical records of our institution....
Mon Mar 16, 2020 02:00
Abstract The diagnosis of breast cancer currently relies on radiological and clinical evaluation, confirmed by histopathological examination. However, such approach has some limitations as the suboptimal sensitivity, the long turnaround time for recall tests, the invasiveness of the procedure and the risk that some features of target lesions may remain undetected, making re-biopsy a necessity. Recent technological advances in the field of artificial intelligence hold promise...
Mon Mar 16, 2020 02:00
Iron overload is commonly seen in the context of hematological diseases in patients who require frequent transfusions. On the other hand, an association between autoimmune hemolytic anemia complicating chronic lymphocytic leukemia and iron overload is unusual. Here, we report 2 cases of iron overload in patients with a background of chronic lymphocytic leukemia complicated by autoimmune hemolytic anemia. Both patients were found to have a high liver iron concentration on liver MRI (FerriScan). This...
Mon Mar 16, 2020 11:30
האקדמיה ללשון העברית והתאחדות האדריכלים ובוני ערים בישראל מכריזות על תחרות פומבית לתכנון מִנווה בקריית הלאום בירושלים. לפני שנים אחדות יזמה האקדמיה ללשון העברית הקמה של בית חדש שיתאים לפעילותה המתרחבת, בית שיהיה מרכז אקדמי־תרבותי־חינוכי ללשון העברית ויכלול מפעלי מחקר חדשים ומוזאון לאומי לעברית. היוזמה אומצה בהחלטת ממשלת ישראל בכסלו תשע"ג (נובמבר 2012), ולקריה החדשה יוחד השם "מִנווה". האקדמיה פועלת לקידום הקמת המנווה בסיוע עיריית ירושלים והרשות לפיתוח ירושלים. מנווה האקדמיה ללשון העברית עתיד לקום...
Mon Mar 16, 2020 09:44
This review covers original articles using deep learning in the biophotonic field published in the last years. In these years deep learning, which is a subset of machine learning mostly based on artificial neural network geometries, was applied to a number of biophotonic tasks and has achieved state‐of‐the‐art performances. Therefore, deep learning in the biophotonic field is rapidly growing and it will be utilized in the next years to obtain real‐time biophotonic decision‐making systems and to analyse...
Mon Mar 16, 2020 11:36
Abstract This study aimed at visualizing relative relaxation time constant in soft tissue by using optical coherence elastography. We proposed a force vibration model as a theoretical base to express relaxation time constant (RTC) using axial gradient of periodic vibration phase captured by phase sensitive optical coherence tomography (PhS‐OCT). Validation of the model had been accomplished by experiments with isotropic and double layered phantoms. A fresh chicken breast sample treated with focused...
Mon Mar 16, 2020 11:36
Abstract The main objective of this work was the development of a novel 2D dosimetry approach for small animal external radiotherapy using radioluminescence imaging (RLI) with a commercial complementary metal oxide semiconductor detector. Measurements of RLI were performed on the small animal image‐guided platform SmART, RLI data were corrected for perspective distortion using Matlab. Four irradiation fields were tested and the planar 2D dose distributions and dose profiles were compared against...
Mon Mar 16, 2020 11:36
Abstract Haemolysis is a very common phenomenon and is referred as the release of intracellular components from red blood cells to the extracellular fluid. Haemolysed samples are often rejected in clinics due to the interference of haemoglobin and intracellular components in laboratory measurements. Plasma and serum based vibrational spectroscopy studies are extensively applied to generate spectral biomarkers for various diseases. However, no studies have reported the effect of haemolysis in blood...
Mon Mar 16, 2020 11:36
The original version of this article unfortunately contained mistakes in Tables 1 and 3.
Mon Mar 16, 2020 11:05
The article type for this article should be Original Research paper.
Mon Mar 16, 2020 11:05
Objective: To compare functional hearing preservation (HP) with a slim perimodiolar array (SPA) and a slim lateral wall array (SLW) in cochlear implantation (CI). Study Design: Retrospective chart review. Setting: Tertiary referral center. Patients: All adult, post-lingual CI recipients with serviceable preoperative hearing serially implanted with SPA or SLW electrodes from July 2015 through July 2018. Interventions: Cochlear implantation. Main Outcome Measures: Hearing...
Fri Mar 13, 2020 02:00
Introduction: Three-dimensional (3D) tools have played a significant role in advancing anatomical knowledge, in simulation and clinical practice in Otology. Technology is evolving at a rapid rate with new applications being reported at an overwhelming pace. It is important to continuously review new applications, assess emerging trends, and identify challenges to innovation so clinical translation progresses in an efficient and evidenced-based manner. Methods: A review of 20 years of literature...
Fri Mar 13, 2020 02:00
Introduction: This study aimed to investigate the association between candidate genetic variants and audiometric measures of noise-induced hearing loss (NIHL) in young musicians. Methods: The study analyzed a database by Phillips et al. (Feasibility of a bilateral 4000–6000 Hz notch as a phenotype for genetic association analysis. Int J Audiol 2015;54:645–52.) which included behavioral hearing thresholds, distortion-product otoacoustic emissions (DPOAE), tympanometric, and genetic data of...
Fri Mar 13, 2020 02:00
Abstract Introduction The aim of this study is to determine whether 99mTc-MAA SPECT/CT-based dosimetry could predict the actual absorbed dose in hepatocellular carcinoma (HCC) or liver metastases, treated by glass or resin microspheres. Material and methods Fifty-seven patients who underwent selective internal radiation therapy (SIRT)...
Mon Mar 16, 2020 09:55
Mon Mar 16, 2020 09:55
Abstract Purpose As an alternative to technetium-99m-macroaggregated albumin (99mTc-MAA), a scout dose of holmium-166 (166Ho) microspheres can be used prior to 166Ho-radioembolization. The use of identical particles for pre-treatment and treatment procedures may improve the predictive value of pre-treatment analysis of distribution. The aim of this study was to analyze the agreement between 166Ho-scout and 166Ho-therapeutic dose...
Mon Mar 16, 2020 09:55
Abstract Background Technetium-99m macroaggregated albumin is used to estimate lung shunt fraction (LSF) prior to yttrium-90 (Y90). Studies have debated the safety and efficacy of Y90 in patients with LSF > 15%. We aimed to assess the role of Y90 in hepatocellular carcinoma (HCC) with LSF > 15%. Methods With IRB approval, we searched...
Mon Mar 16, 2020 09:55
Abstract Purpose Peptide receptor radionuclide therapy (PRRT) is effective for metastatic/inoperable neuroendocrine tumors (NETs). Imaging response assessment is usually efficient subsequent to treatment completion. Blood biomarkers such as PRRT Predictive Quotient (PPQ) and NETest are effective in real-time. PPQ predicts PRRT efficacy; NETest monitors disease. We prospectively evaluated: (1) NETest as a surrogate biomarker for...
Mon Mar 16, 2020 09:55
Abstract Aim One of the primary prerequisites for peptide receptor radionuclide therapy (PRRT) in patients with neuroendocrine tumors (NET) is the presence of somatostatin receptors (SSTR) on NET cells. NET are highly heterogeneous and an individual patient as well as separate metastases can harbor cells with different clones, which influence the SSTR expression on NET cells. With this background we looked into our institutional...
Mon Mar 16, 2020 09:55
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