Abstract Objective To assess the association of public health parameters with the regional variation in the initial treatment for prostate cancer. Methods We used data from German epidemiologic cancer registries for the years 2009–2013. Presence of a certified cancer center, a radiotherapy and/or urology institution, the district-specific GDP, and population...
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Abstract Purpose IHC, FISH, and NGS are common methods of ALK evaluation in NSCLC. The purpose of this study was to investigate whether ALK false positives or false negatives occurred more often in daily routines. An approach to identify ALK fusion was then proposed. Materials and methods We analyzed 1815 cases of NSCLC, including 83 (4.6%) ALK IHC positives....
Tue Mar 03, 2020 02:00
Abstract Purpose Cerebral aneurysms are one of the prevalent cerebrovascular disorders in adults worldwide and caused by a weakness in the brain artery. The most impressive treatment for a brain aneurysm is interventional radiology treatment, which is extremely dependent on the skill level of the radiologist. Hence, accurate detection and effective therapy for cerebral aneurysms still remain important clinical challenges. In this work,...
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This case report describes a combined neurosurgical and endovascular approach for the treatment of a conus medullaris arteriovenous malformation resulting in considerable improvement in the patient’s neurological condition (modified Rankin Scale score 2).
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Pediatric spinal vascular malformations are rare entities that typically present with symptoms from their effect on surrounding structures. Here we report a unique case of lumbar spinal dural/perimedullary arteriovenous fistula (AVF) that presented with intraventricular hemorrhage and hydrocephalus. The previously healthy child presented with lethargy and headache, and initial imaging revealed only ventriculomegaly with trace intraventricular blood. His mental status improved with CSF diversion via...
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A football player was diagnosed with myositis ossificans of his right adductor longus muscle after an acute injury. Conservative treatment failed and 1 year after the initial trauma the patient underwent surgical excision of a large ossification. Seven months postoperatively, the patient was fully recovered and returned to his preinjury activity levels. We present our approach to this case and discuss our considerations, referring to background information about this rare disease.
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M Sivasankari, Preema SinhaJournal of Marine Medical Society 2020 22(1):84-86 Onychomadesis is a nail plate abnormality with temporary cessation in the growth of the nail plate due to disturbances in the nail matrix. Any local or systemic condition affecting the nail matrix directly or indirectly can lead to onychomadesis. The causes can vary from idiopathic infections to systemic causes. Although onychomadesis is not a finding unique to any disease, it indicates the presence of a preceding trigger,...
Tue Mar 03, 2020 00:00
Sandeep Arora, Sandeep Lal, Manasa Shettisara Janney, Eeshaan Ranjan, Navya Donaparthi, Rajeshwari DabasJournal of Marine Medical Society 2020 22(1):50-53 Context: Pharmacotherapy is the standard first-line management of onychomycosis (OM). Prolonged treatment courses have reported cure rates of only 40%–80%. Although lasers have been approved by the US Food and Drug Administration for the clearance of nail in OM, their efficacy in the first-line management is not established. In this context,...
Tue Mar 03, 2020 00:00
Kavita Bala Anand, Supreet Mohanty, V ManuJournal of Marine Medical Society 2020 22(1):54-56 Introduction: Hepatitis B is a vaccine preventable disease caused by Hepatitis B virus which is a partially double stranded virus. Sharp injuries are the most common occupational injuries among healthcare workers (HCW). HCW are prone to sharp injuries during work, and infection after exposure. Materials and Methods: Anti-HBs titres were measured in 231 HCW in a tertiary care hospital in Mumbai. Result:...
Tue Mar 03, 2020 00:00
Anmol Sharma, Sougat Ray, Joydeep Choudhury, Rahul TyagiJournal of Marine Medical Society 2020 22(1):96-100 Rat-borne diseases including leptospirosis have been of historical importance in the military. With the risk of human–rat encounters onboard ships and vessels, encountering such an illness at sea is not rare for a primary care physician. Thus, it becomes important for those at the front, to be aware of its presentation and management. Leptospirosis must always be considered as a differential...
Tue Mar 03, 2020 00:00
Ankur Ahuja, Tathagat Chatterjee, Meghna Yadav, Sonia Badwal, Gaurav PS Gahlot, Beenu SinghJournal of Marine Medical Society 2020 22(1):57-61 Background: Usually, hematolymphoid malignancies present as generalized lymphadenopathy, splenomegaly, and cytopenias. However, sometimes, this may not be the scenario, and that is where the challenge arises. These unusual scenarios are present either in extranodal lymphoma or extramedullary acute leukemia, especially occurring at unusual sites and these...
Tue Mar 03, 2020 00:00
Alok Jaiswal, Debashish Paul, Shalendra Singh, Arijit RayJournal of Marine Medical Society 2020 22(1):103-104
Tue Mar 03, 2020 00:00
Abstract Purpose To identify distinct trajectories of total moderate-to-vigorous physical activity (MVPA) and sedentary behavior following a breast cancer diagnosis and their correlates. Methods The analysis examined 3000 female breast cancer survivors within Kaiser Permanente Northern California between 2006 and 2013. Self-reported time spent on total...
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Abstract It is well‐known that goal‐directed hand movements can be adjusted to small changes in target location with a latency of about 100 ms. We tested whether people make similar fast adjustments when a target location for foot placement changes slightly as they walk over a flat surface. Participants walked at 3 km/h on a treadmill on which stepping stones were projected. The stones were 50 cm apart in the walking direction. Every 5–8 steps, a stepping stone was unexpectedly displaced by 2.5 cm...
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Abstract Aims Endurance athletes develop cardiac remodeling to cope with increased cardiac output during exercise. This remodeling is both anatomical and functional and shows large interindividual variability. In this study, we quantify local geometric ventricular remodeling related to long-standing endurance training and assess its relationship with cardiovascular performance during exercise. ...
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This study aims to assess antimicrobial consumption in the pediatric department of a tertiary care public hospital in Zimbabwe. Clinical records of pediatric inpatients admitted to Harare Central Hospital over a 3-week period were reviewed prospectively. Antimicrobial consumption was described as days of therapy per 100 inpatient days (DOT/100 PD). Adherence of antimicrobial drug prescriptions to the National Guidelines was also evaluated. A total of 121 (93.1%) children were prescribed at least...
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CONCLUSIONS: Our study provides clinically useful real-world data on radium-223, highlighting the importance of multidisciplinary patient management to guarantee the best continuum of care for patients with mCRPC. PMID: 32116138 [PubMed - as supplied by publisher] (Source: Tumori)
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CONCLUSIONS: mrEMVI positivity is an independent risk factor for synchronous distant metastasis in rectal cancer. mrEMVI score 4 is a stronger risk factor for synchronous metastasis than mrEMVI score 3 in rectal cancer. PMID: 32116150 [PubMed - as supplied by publisher] (Source: Tumori)
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Screening high risk current or former smokers identified at annual reviews for chronic obstructive pulmonary disease (COPD) as part of routine primary care led to 2% receiving a lung cancer...
08:31
The stalling infant mortality rates in the UK should be a “wake up call” for the nation, according to leading paediatricians.The UK is fifth from the bottom among 27 European countries for infant...
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bmj;368/mar03_19/m856/FAF1faDai Kurokawa/EPA-EFE/ShutterstockLocal farmer Theophilus Mwendwa runs through a swarm of desert locusts trying to disperse them in the bush near Enziu, Kitui County,...
Tue Mar 03, 2020 19:26
Doctors from leading Chinese hospitals admitted in undercover phone calls that organs harvested from Falun Gong detainees were available, an informal, independent “people’s tribunal” has...
Tue Mar 03, 2020 19:16
Yet again a lone “bad egg”—Ian Paterson, the rogue breast surgeon—has put the public’s faith and trust in doctors at risk. The inquiry into Paterson’s case found that an NHS trust and a private...
Tue Mar 03, 2020 17:25
In Smith and colleagues’ analysis in The BMJ’s Quality Improvement series of infomercial articles, “Lean” is mentioned no less than 42 times.1 Lean seems to talk a lot about using Lean to talk about...
Tue Mar 03, 2020 17:26
Park and colleagues discuss medical responses to a terrorist attack, mentioning the model used by the French National Police Special Intervention Unit.1 Another model is the one chosen by the French...
Tue Mar 03, 2020 11:16
US public health watchdogs have been failing for years in their legal duty to inform the public about the results of clinical trials, a federal court has found.The US district court for southern New...
Mon Mar 02, 2020 17:11
A senior employee of the US Department of Health and Human Services has filed a whistleblower complaint alleging that untrained staff were sent without proper protective equipment to meet the first...
Mon Mar 02, 2020 17:01
Recently retired doctors may be asked to return to work as part of the UK’s covid-19 response, according to health secretary Matt Hancock.Speaking on The Andrew Marr Show on 1 March, Hancock said...
Mon Mar 02, 2020 16:31
Canada’s government has tabled new legislation that would remove some of the restrictions placed on medical aid in dying, most notably the requirement that applicants suffer from a terminal condition...
Mon Mar 02, 2020 15:16
Critics have branded an EU funded trial looking at the potential for personalised breast cancer screening “a missed opportunity” for failing to fully evaluate the benefits and harms of screening.Four...
Tue Mar 03, 2020 17:11
Healthcare staff on leave and those who have retired could be called “back to duty,” and non-urgent care could be delayed, as doctors are forced to prioritise dealing with covid-19, the UK...
Tue Mar 03, 2020 16:21
Is there some sort of higher calling to join the medical profession, or is it simply a highly skilled job? This age old debate generates more heat than light, and it’s not clear why the two need to...
Tue Mar 03, 2020 14:46
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