Antibiotics, Vol. 9, Pages 574: Impact of Albumin and Omeprazole on Steady-State Population Pharmacokinetics of Voriconazole and Development of a Voriconazole Dosing Optimization Model in Thai Patients with Hematologic Diseases Antibiotics doi: 10.3390/antibiotics9090574 Authors: Buddharat Khan-asa Baralee Punyawudho Noppaket Singkham Piyawat Chaivichacharn Ekapun Karoopongse Methee Chayakulkeeree Preecha Montakantikul This study aimed to identify factors that significantly...
Thu Sep 03, 2020 03:00
Antibiotics, Vol. 9, Pages 573: Antibiotics Differentially Modulate Lipoteichoic Acid-Mediated Host Immune Response Antibiotics doi: 10.3390/antibiotics9090573 Authors: Marquerita Algorri Annie Wong-Beringer In Staphylococcus aureus bacteremia, our group has shown that a dysregulated balance of pro- and anti-inflammatory cytokine response biased towards an immunoparalysis phenotype is predictive of persistence and mortality, despite receipt of antibiotics. Certain antibiotics, as...
Thu Sep 03, 2020 03:00
Antibiotics, Vol. 9, Pages 572: Synthesis of Electrospun TiO2 Nanofibers and Characterization of Their Antibacterial and Antibiofilm Potential against Gram-Positive and Gram-Negative Bacteria Antibiotics doi: 10.3390/antibiotics9090572 Authors: Mohammad Azam Ansari Hani Manssor Albetran Muidh Hamed Alheshibri Abdelmajid Timoumi Norah Abdullah Algarou Sultan Akhtar Yassine Slimani Munirah Abdullah Almessiere Fatimah Saad Alahmari Abdulhadi Baykal It-Meng Low ...
Thu Sep 03, 2020 03:00
Antibiotics, Vol. 9, Pages 571: Guideline Adherence in Antibiotic Prescribing to Patients with Respiratory Diseases in Primary Care: Prevalence and Practice Variation Antibiotics doi: 10.3390/antibiotics9090571 Authors: Karin Hek Thamar E.M. van Esch Anke Lambooij Yvette M. Weesie Liset van Dijk Respiratory tract infections (RTIs) account for a large part of antibiotic prescriptions in primary care. However, guidelines advise restrictive antibiotic prescribing for RTIs. Only...
Thu Sep 03, 2020 03:00
Antioxidants, Vol. 9, Pages 826: Chemical Profile, Antioxidant, Anti-Inflammatory, and Anti-Cancer Effects of Italian Salvia rosmarinus Spenn. Methanol Leaves Extracts Antioxidants doi: 10.3390/antiox9090826 Authors: Brindisi Bouzidi Frattaruolo Loizzo Tundis Dugay Deguin Cappello Cappello In this study, we evaluated and compared the chemical composition, the antioxidant, anti-inflammatory, and anti-proliferative effects of four methanol extracts (R1–R4),...
Thu Sep 03, 2020 03:00
Antioxidants, Vol. 9, Pages 821: Nephroprotective Effect of Cilastatin against Gentamicin-Induced Renal Injury In Vitro and In Vivo without Altering Its Bactericidal Efficiency Antioxidants doi: 10.3390/antiox9090821 Authors: Juan Carlos Jado Blanca Humanes María Ángeles González-Nicolás Sonia Camaño José Manuel Lara Beatriz López Emilia Cercenado Julio García-Bordas Alberto Tejedor Alberto Lázaro Gentamicin is a used antibiotic that causes nephrotoxicity in...
Thu Sep 03, 2020 03:00
Antioxidants, Vol. 9, Pages 824: Anti-inflammatory and Anti-oxidant Activity of Hidrox® in Rotenone-Induced Parkinson’s Disease in Mice Antioxidants doi: 10.3390/antiox9090824 Authors: Rosalba Siracusa Maria Scuto Roberta Fusco Angela Trovato Maria Laura Ontario Roberto Crea Rosanna Di Paola Salvatore Cuzzocrea Vittorio Calabrese Background: In developed countries, the extension of human life is increasingly accompanied by a progressive increase in neurodegenerative...
Thu Sep 03, 2020 03:00
Antioxidants, Vol. 9, Pages 823: Ubiquinone Supplementation with 300 mg on Glycemic Control and Antioxidant Status in Athletes: A Randomized, Double-Blinded, Placebo-Controlled Trial Antioxidants doi: 10.3390/antiox9090823 Authors: Chien-Chang Ho Po-Sheng Chang Hung-Wun Chen Po-Fu Lee Yun-Chi Chang Ching-Yu Tseng Ping-Ting Lin The aim of this study is to investigate the glycemic profile, oxidative stress, and antioxidant capacity in athletes after 12 weeks of ubiquinone...
Thu Sep 03, 2020 03:00
Antioxidants, Vol. 9, Pages 825: An Integrated Strategy for Nutraceuticals from Haematoccus pluvialis: From Cultivation to Extraction Antioxidants doi: 10.3390/antiox9090825 Authors: Sanjeet Mehariya Neeta Sharma Angela Iovine Patrizia Casella Tiziana Marino Vincenzo Larocca Antonio Molino Dino Musmarra The aim of this study was to develop an effective integrated cultivation system for Haematococcus pluvialis as a source of bioactive compounds such as astaxanthin,...
Thu Sep 03, 2020 03:00
Antioxidants, Vol. 9, Pages 822: Influence of Accelerated Solvent Extraction Conditions on the LC-ESI-MS/MS Polyphenolic Profile, Triterpenoid Content, and Antioxidant and Anti-lipoxygenase Activity of Rhododendron luteum Sweet Leaves Antioxidants doi: 10.3390/antiox9090822 Authors: Marta Olech Lena Łyko Renata Nowak Evaluation of native plant resources and their efficient use is one of the current trends in phytochemistry. The main aim of the present study was to investigate the...
Thu Sep 03, 2020 03:00
Antioxidants, Vol. 9, Pages 820: Methylglyoxal-Induced Dysfunction in Brain Endothelial Cells via the Suppression of Akt/HIF-1α Pathway and Activation of Mitophagy Associated with Increased Reactive Oxygen Species Antioxidants doi: 10.3390/antiox9090820 Authors: Donghyun Kim Kyeong-A Kim Jeong-Hyeon Kim Eun-Hye Kim Ok-Nam Bae Methylglyoxal (MG) is a dicarbonyl compound, the level of which is increased in the blood of diabetes patients. MG is reported to be involved in the...
Thu Sep 03, 2020 03:00
Atmosphere, Vol. 11, Pages 943: Quasi-Biennial Oscillation and Sudden Stratospheric Warmings during the Last Glacial Maximum Atmosphere doi: 10.3390/atmos11090943 Authors: Fu Wang White Pahlavan Alexander Wallace The quasi-biennial oscillation (QBO) and sudden stratospheric warmings (SSWs) during the Last Glacial Maximum (LGM) are investigated in simulations using the Whole Atmosphere Community Climate Model version 6 (WACCM6). We find that the period of QBO, which...
Thu Sep 03, 2020 03:00
Atmosphere, Vol. 11, Pages 942: Dynamics of Mechanical Oscillator Mechanism for Stratospheric Gravity Waves Generated by Convection Atmosphere doi: 10.3390/atmos11090942 Authors: Shiwang Yu Lifeng Zhang Ming Zhang Yuan Wang The mechanical oscillator mechanism (MOM) for stratospheric gravity waves generated by convection is investigated with a dynamics model using the two-dimensional, nonhydrostatic and linear governing equations based on the Boussinesq approximation. The model...
Thu Sep 03, 2020 03:00
Atmosphere, Vol. 11, Pages 941: Wildfire Smoke Transport and Air Quality Impacts in Different Regions of China Atmosphere doi: 10.3390/atmos11090941 Authors: Fengjun Zhao Yongqiang Liu Lifu Shu Qi Zhang The air quality and human health impacts of wildfires depend on fire, meteorology, and demography. These properties vary substantially from one region to another in China. This study compared smoke from more than a dozen wildfires in Northeast, North, and Southwest China to understand...
Thu Sep 03, 2020 03:00
Atmosphere, Vol. 11, Pages 940: Abnormal Strong Upwelling off the Coast of Southeast Vietnam in the Late Summer of 2016: A Comparison with the Case in 1998 Atmosphere doi: 10.3390/atmos11090940 Authors: Fuan Xiao Zhifeng Wu Yushan Lyu Yicen Zhang The traditional view holds that a weakened upwelling has often been observed off the coast of southeast Vietnam during the post-El Niño summer. This study investigated a strong upwelling and concurrent phytoplankton bloom...
Thu Sep 03, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 134: Jealousy Incarnate: Quiet Ego, Competitive Desire, and the Fictional Intelligence of Long-Term Mating in a Romantic K-Drama Behavioral Sciences doi: 10.3390/bs10090134 Authors: Lorenza Lucchi Basili Pier Luigi Sacco In this paper, we analyze a K-drama aired by the Korean TV network SBS in 2016, Jealousy Incarnate, as a case study of the application of the Tie-Up Theory to a romantic narrative as a form of simulation of human mating processes...
Thu Sep 03, 2020 03:00
Biology, Vol. 9, Pages 266: Soybean Plant Metabolism under Water Deficit and Xenobiotic and Antioxidant Agent Application Biology doi: 10.3390/biology9090266 Authors: Julia Renata Schneider Mariele Müller Vilson Antonio Klein Luciana Grazziotin Rossato-Grando Rômulo Pillon Barcelos Genei Antonio Dalmago Geraldo Chavarria The aim was to evaluate the interactive effects on biochemistry and physiology of soybean plants exposed to simultaneous xenobiotic and water deficit...
Thu Sep 03, 2020 03:00
Biomedicines, Vol. 8, Pages 327: Antibody-Based Immunotherapy: Alternative Approaches for the Treatment of Metastatic Melanoma Biomedicines doi: 10.3390/biomedicines8090327 Authors: Fleury Augustin Nsole Biteghe Nyangone Ekome Toung Chalomie Neelakshi Mungra Guillaume Vignaux Nan Gao Aurelia Vergeade Ambrose Okem Krupa Naran Jean De La Croix Ndong Stefan Barth Melanoma is the least common form of skin cancer and is associated with the highest mortality. Where...
Thu Sep 03, 2020 03:00
Biomedicines, Vol. 8, Pages 326: 4-Hydroxynonenal Immunoreactivity Is Increased in the Frontal Cortex of 5XFAD Transgenic Mice Biomedicines doi: 10.3390/biomedicines8090326 Authors: Sang-Wook Shin Dong-Hee Kim Won Kyung Jeon Jung-Soo Han Oxidative stress was implicated in the functional impairment of the frontal cortex observed in early Alzheimer’s disease (AD). To elucidate this role in an animal AD model, we assessed cognitive function of 4-month-old five familial...
Thu Sep 03, 2020 03:00
Biomolecules, Vol. 10, Pages 1274: The Zebrafish Perivitelline Fluid Provides Maternally-Inherited Defensive Immunity Biomolecules doi: 10.3390/biom10091274 Authors: Javiera F. De la Paz Consuelo Anguita-Salinas César Díaz-Celis Francisco P. Chávez Miguel L. Allende In the teleost egg, the embryo is immersed in an extraembryonic fluid that fills the space between the embryo and the chorion and partially isolates it from the external environment, called the perivitelline fluid...
Thu Sep 03, 2020 03:00
Biomolecules, Vol. 10, Pages 1275: Hepatic Lipidomics and Molecular Imaging in a Murine Non-Alcoholic Fatty Liver Disease Model: Insights into Molecular Mechanisms Biomolecules doi: 10.3390/biom10091275 Authors: Ricardo Rodríguez-Calvo Sara Samino Josefa Girona Neus Martínez-Micaelo Pere Ràfols María García-Altares Sandra Guaita-Esteruelas Alexandra Junza Mercedes Heras Oscar Yanes Xavier Correig Lluis Masana An imbalance between hepatic fatty acid uptake...
Thu Sep 03, 2020 03:00
Biomolecules, Vol. 10, Pages 1273: The Skeleton in the Closet: Faults and Strengths of Public Versus Private Genetic Biobanks Biomolecules doi: 10.3390/biom10091273 Authors: Pamela Tozzo Luciana Caenazzo Direct-to-consumer (DTC) genetic testing has been a major ethical controversy related to clinical utility, the availability of pre- and post-genetic counseling, privacy concerns, and the risk of discrimination and stigmatization. The development of direct-to-consumer genetic testing...
Thu Sep 03, 2020 03:00
Biomolecules, Vol. 10, Pages 1271: Modeling DNA Methylation Profiles through a Dynamic Equilibrium between Methylation and Demethylation Biomolecules doi: 10.3390/biom10091271 Authors: Giulia De Riso Damiano Francesco Giuseppe Fiorillo Annalisa Fierro Mariella Cuomo Lorenzo Chiariotti Gennaro Miele Sergio Cocozza DNA methylation is a heritable epigenetic mark that plays a key role in regulating gene expression. Mathematical modeling has been extensively applied to unravel...
Thu Sep 03, 2020 03:00
Biomolecules, Vol. 10, Pages 1272: The Relationship between the Level of Anterior Cingulate Cortex Metabolites, Brain-Periphery Redox Imbalance, and the Clinical State of Patients with Schizophrenia and Personality Disorders Biomolecules doi: 10.3390/biom10091272 Authors: Amira Bryll Wirginia Krzyściak Paulina Karcz Natalia Śmierciak Tamas Kozicz Justyna Skrzypek Marta Szwajca Maciej Pilecki Tadeusz J. Popiela Schizophrenia is a complex mental disorder whose course...
Thu Sep 03, 2020 03:00
Biomolecules, Vol. 10, Pages 1270: Fallopian Tube Basal Stem Cells Reproducing the Epithelial Sheets In Vitro—Stem Cell of Fallopian Epithelium Biomolecules doi: 10.3390/biom10091270 Authors: Maobi Zhu Tomohiko Iwano Sen Takeda The fallopian tube (FT) is an important reproductive organ in females. The luminal epithelium of the FT is composed of highly polarized secretory and ciliated cells. Recently, accumulating lines of evidence have suggested that the origin of high-grade serous...
Thu Sep 03, 2020 03:00
Biomolecules, Vol. 10, Pages 1269: Noncoding RNAs and Midbrain DA Neurons: Novel Molecular Mechanisms and Therapeutic Targets in Health and Disease Biomolecules doi: 10.3390/biom10091269 Authors: Emilia Pascale Giuseppina Divisato Renata Palladino Margherita Auriemma Edward Faustine Ngalya Massimiliano Caiazzo Midbrain dopamine neurons have crucial functions in motor and emotional control and their degeneration leads to several neurological dysfunctions such as Parkinson’s...
Thu Sep 03, 2020 03:00
Brain Sciences, Vol. 10, Pages 604: Cortical Function in Acute Severe Traumatic Brain Injury and at Recovery: A Longitudinal fMRI Case Study Brain Sciences doi: 10.3390/brainsci10090604 Authors: Karnig Kazazian Loretta Norton Teneille E. Gofton Derek Debicki Adrian M. Owen Differences in the functional integrity of the brain from acute severe brain injury to subsequent recovery of consciousness have not been well documented. Functional magnetic resonance imaging (fMRI) may...
Thu Sep 03, 2020 03:00
Brain Sciences, Vol. 10, Pages 606: Sex and Gender Differences in the Effects of Novel Psychoactive Substances Brain Sciences doi: 10.3390/brainsci10090606 Authors: Liana Fattore Matteo Marti Rafaela Mostallino Maria Paola Castelli Sex and gender deeply affect the subjective effects and pharmaco-toxicological responses to drugs. Men are more likely than women to use almost all types of illicit drugs and to present to emergency departments for serious or fatal intoxications....
Thu Sep 03, 2020 03:00
Brain Sciences, Vol. 10, Pages 607: An Assessment of the Motor Performance Skills of Children with Autism Spectrum Disorder in the Gulf Region Brain Sciences doi: 10.3390/brainsci10090607 Authors: Rehab H. Alsaedi This study aims to determine the prevalence, severity, and nature of the motor abnormalities seen in children with autism spectrum disorder (ASD) as well as to elucidate the associated developmental profiles. The short-form of the Bruininks-Oseretsky Test of Motor Proficiency,...
Thu Sep 03, 2020 03:00
Brain Sciences, Vol. 10, Pages 605: Evidence for Attentional Phenotypes in Infancy and Their Role in Visual Cognitive Performance Brain Sciences doi: 10.3390/brainsci10090605 Authors: Shannon Ross-Sheehy Esther Reynolds Bret Eschman Infant visual attention rapidly develops during the first year of life, playing a pivotal role in the way infants process, learn, and respond to their visual world. It is possible that individual differences in eye movement patterns shape early experience...
Thu Sep 03, 2020 03:00
Cancers, Vol. 12, Pages 2510: RNA Sequencing of Hepatobiliary Cancer Cell Lines: Data and Applications to Mutational and Transcriptomic Profiling Cancers doi: 10.3390/cancers12092510 Authors: Dominique Scherer Marcela Dávila López Benjamin Goeppert Sanna Abrahamsson Rosa González Silos Igor Nova Katherine Marcelain Juan C. Roa David Ibberson Sinan U. Umu Trine Ballestad Rounge Stephanie Roessler Justo Lorenzo Bermejo Cancer cell lines allow the identification...
Thu Sep 03, 2020 03:00
Cancers, Vol. 12, Pages 2511: Radioresistance in Glioblastoma and the Development of Radiosensitizers Cancers doi: 10.3390/cancers12092511 Authors: Md Yousuf Ali Claudia R Oliva Abu Shadat M Noman Bryan G Allen Prabhat C Goswami Yousef Zakharia Varun Monga Douglas R Spitz John M Buatti Corinne E Griguer Ionizing radiation is a common and effective therapeutic option for the treatment of glioblastoma (GBM). Unfortunately, some GBMs are relatively radioresistant...
Thu Sep 03, 2020 03:00
Cancers, Vol. 12, Pages 2508: Insights into Differentiation of Melanocytes from Human Stem Cells and Their Relevance for Melanoma Treatment Cancers doi: 10.3390/cancers12092508 Authors: Madalina A. Mirea Stefan Eckensperger Markus Hengstschläger Mario Mikula Malignant melanoma represents a highly aggressive form of skin cancer. The metastatic process itself is mostly governed by the so-called epithelial mesenchymal transition (EMT), which confers cancer cells migrative, invasive...
Thu Sep 03, 2020 03:00
Cancers, Vol. 12, Pages 2507: Tumors of the Central Nervous System: An Update Cancers doi: 10.3390/cancers12092507 Authors: Carla Mucignat-Caretta The brain may be affected by a variety of tumors of different grade, which originate from different cell types at distinct locations, thus impacting on the brain structure and function [...]
Thu Sep 03, 2020 03:00
Cancers, Vol. 12, Pages 2506: Hypofractionated Radiotherapy for Anaplastic Thyroid Cancer: Systematic Review and Pooled Analysis Cancers doi: 10.3390/cancers12092506 Authors: Dmytro Oliinyk Teresa Augustin Viktoria Florentine Koehler Josefine Rauch Claus Belka Christine Spitzweg Lukas Käsmann Anaplastic thyroid carcinoma (ATC) is associated with a poor prognosis due to aggressive tumor growth and high treatment resistance. Hypofractionated treatment concepts may be...
Thu Sep 03, 2020 03:00
Cancers, Vol. 12, Pages 2509: The Optimal Duration of Adjuvant Chemotherapy in Colon Cancer Cancers doi: 10.3390/cancers12092509 Authors: Maike Collienne Dirk Arnold Adjuvant chemotherapy for colon cancer (UICC stage II and III) has been under investigation over the last 30 years, regarding treatment duration and regimens. In this review, choice of regimen, its duration, possible limitations and future perspectives are discussed. Monotherapy with 5-fluorouracil was followed by addition...
Thu Sep 03, 2020 03:00
Cancers, Vol. 12, Pages 2503: ArticlePre- and Post-Zygotic TP53 De Novo Mutations in SHH-Medulloblastoma Cancers doi: 10.3390/cancers12092503 Authors: Jacopo Azzollini Elisabetta Schiavello Francesca Romana Buttarelli Carlo Alfredo Clerici Laura Tizzoni Giovanna De Vecchi Fabio Capra Federica Pisati Veronica Biassoni Letterio Runza Giorgio Carrabba Felice Giangaspero Maura Massimino Valeria Pensotti Siranoush Manoukian Li-Fraumeni syndrome (LFS)...
Thu Sep 03, 2020 03:00
Cancers, Vol. 12, Pages 2500: PI3K p110α Blockade Enhances Anti-Tumor Efficacy of Abemaciclib in Human Colorectal Cancer Cells Cancers doi: 10.3390/cancers12092500 Authors: Hyun Jung Lee Kui-Jin Kim Ji Hea Sung Milang Nam Koung Jin Suh Ji-Won Kim Se Hyun Kim Jin Won Kim Yu Jung Kim Keun-Wook Lee Jong Seok Lee Jee Hyun Kim Targeting cell cycle regulation in colorectal cancer has not been fully evaluated. We investigated the efficacy of the CDK4/6 inhibitor,...
Thu Sep 03, 2020 03:00
Cancers, Vol. 12, Pages 2504: Chronic Lymphocytic Leukemia Cancers doi: 10.3390/cancers12092504 Authors: Tiziana Vaisitti Francesca Arruga Alessandra Ferrajoli This Special Issue of Cancers, made up of nine articles (four original papers, four reviews, and a brief report), is dedicated to chronic lymphocytic leukemia (CLL) [...]
Thu Sep 03, 2020 03:00
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