Antibiotics, Vol. 9, Pages 565: Vancomycin-Resistant Enterococci (VRE) in Nigeria: The First Systematic Review and Meta-Analysis Antibiotics doi: 10.3390/antibiotics9090565 Authors: Yusuf Wada Azian Binti Harun Chan Yean Yean Abdul Rahman Zaidah Vancomycin-Resistant Enterococci (VRE) are on the rise worldwide. Here, we report the first prevalence of VRE in Nigeria using systematic review and meta-analysis. International databases MedLib, PubMed, International Scientific Indexing...
Tue Sep 01, 2020 03:00
Antibiotics, Vol. 9, Pages 564: Phages as a Cohesive Prophylactic and Therapeutic Approach in Aquaculture Systems Antibiotics doi: 10.3390/antibiotics9090564 Authors: Maciej Żaczek Beata Weber-Dąbrowska Andrzej Górski Facing antibiotic resistance has provoked a continuously growing focus on phage therapy. Although the greatest emphasis has always been placed on phage treatment in humans, behind phage application lies a complex approach that can be usefully adopted by the food industry,...
Tue Sep 01, 2020 03:00
Antibodies, Vol. 9, Pages 44: CD47 as a Potential Target to Therapy for Infectious Diseases Antibodies doi: 10.3390/antib9030044 Authors: Lamin B. Cham Tom Adomati Fanghui Li Murtaza Ali Karl S. Lang The integrin associated protein (CD47) is a widely and moderately expressed glycoprotein in all healthy cells. Cancer cells are known to induce increased CD47 expression. Similar to cancer cells, all immune cells can upregulate their CD47 surface expression during infection....
Tue Sep 01, 2020 03:00
Antioxidants, Vol. 9, Pages 814: Health-Promoting Effects of Thymus Phenolic-Rich Extracts: Antioxidant, Anti-Inflammatory and Antitumoral Properties Antioxidants doi: 10.3390/antiox9090814 Authors: Afonso Pereira Cardoso Thymus genus comprises numerous species that are particularly abundant in the West Mediterranean region. A growing body of evidence suggests that many of these species are a rich source of bioactive compounds, including phenolic compounds such as rosmarinic...
Tue Sep 01, 2020 03:00
Antioxidants, Vol. 9, Pages 813: The Sorbus spp.—Underutilised Plants for Foods and Nutraceuticals: Review on Polyphenolic Phytochemicals and Antioxidant Potential Antioxidants doi: 10.3390/antiox9090813 Authors: Sarv Venskutonis Bhat The Sorbus spp. are valuable plants, which have been used for ornamental purposes, in traditional medicines and less seldom in foods. Recent studies have revealed different anatomical parts of the Sorbus spp. to contain valuable phytochemicals...
Tue Sep 01, 2020 03:00
Antioxidants, Vol. 9, Pages 815: Natural Antioxidants from Seeds and Their Application in Meat Products Antioxidants doi: 10.3390/antiox9090815 Authors: Munekata Gullón Pateiro Tomasevic Domínguez Lorenzo The use of synthetic antioxidants in the food industry has raised important questions about the effects of prolonged consumption on human health. On top of that, the consumption of meat products has been changing due to the awareness generated by health-related...
Tue Sep 01, 2020 03:00
Antioxidants, Vol. 9, Pages 812: Natural Nrf2 Modulators for Skin Protection Antioxidants doi: 10.3390/antiox9090812 Authors: Yong Chool Boo Since the discovery of antioxidant responsive elements (ARE), which are commonly found in the promoter of the Phase II metabolism/antioxidant enzymes, and nuclear factor erythroid 2-related factor 2 (Nrf2), the transcription factor that binds to ARE, the study conducted in this field has expanded remarkably over the decades, and the Nrf2-mediated...
Tue Sep 01, 2020 03:00
Antioxidants, Vol. 9, Pages 811: Rosemary Flowers as Edible Plant Foods: Phenolic Composition and Antioxidant Properties in Caenorhabditis elegans Antioxidants doi: 10.3390/antiox9090811 Authors: Cristina Moliner Víctor López Lillian Barros Maria Inês Dias Isabel C. F. R. Ferreira Elisa Langa Carlota Gómez-Rincón Rosmarinus officinalis L., commonly known as rosemary, has been largely studied for its wide use as food ingredient and medicinal plant; less attention has...
Tue Sep 01, 2020 03:00
Antioxidants, Vol. 9, Pages 809: Melatonin-Induced Water Stress Tolerance in Plants: Recent Advances
Antioxidants, Vol. 9, Pages 809: Melatonin-Induced Water Stress Tolerance in Plants: Recent Advances Antioxidants doi: 10.3390/antiox9090809 Authors: Mohamed Moustafa-Farag Ahmed Mahmoud Marino B. Arnao Mohamed S. Sheteiwy Mohamed Dafea Mahmoud Soltan Amr Elkelish Mirza Hasanuzzaman Shaoying Ai Water stress (drought and waterlogging) is severe abiotic stress to plant growth and development. Melatonin, a bioactive plant hormone, has been widely tested in drought...
Tue Sep 01, 2020 03:00
Antioxidants, Vol. 9, Pages 810: Irisin Mitigates Oxidative Stress, Chondrocyte Dysfunction and Osteoarthritis Development through Regulating Mitochondrial Integrity and Autophagy Antioxidants doi: 10.3390/antiox9090810 Authors: Feng-Sheng Wang Chung-Wen Kuo Jih-Yang Ko Yu-Shan Chen Shao-Yu Wang Huei-Jing Ke Pei-Chen Kuo Chin-Huei Lee Jian-Ching Wu Wen-Bin Lu Ming-Hong Tai Holger Jahr Wei-Shiung Lian Compromised autophagy and mitochondrial dysfunction...
Tue Sep 01, 2020 03:00
Beverages, Vol. 6, Pages 54: Liquid Chromatographic Approach for the Discrimination and Classification of Cava Samples Based on the Phenolic Composition Using Chemometric Methods Beverages doi: 10.3390/beverages6030054 Authors: Anaïs Izquierdo-Llopart Javier Saurina Phenolic profiles obtained by liquid chromatography with UV/vis detection were here exploited to classify cava samples from the protected designation of origin Cava. Wine samples belonging to various classes which differed...
Tue Sep 01, 2020 03:00
Bioengineering, Vol. 7, Pages 103: Additive Manufacturing of Prostheses Using Forest-Based Composites Bioengineering doi: 10.3390/bioengineering7030103 Authors: Erik Stenvall Göran Flodberg Henrik Pettersson Kennet Hellberg Liselotte Hermansson Martin Wallin Li Yang A custom-made prosthetic product is unique for each patient. Fossil-based thermoplastics are the dominant raw materials in both prosthetic and industrial applications; there is a general demand for reducing...
Tue Sep 01, 2020 03:00
Biology, Vol. 9, Pages 261: Deep Learning Neural Network Prediction Method Improves Proteome Profiling of Vascular Sap of Grapevines during Pierce’s Disease Development Biology doi: 10.3390/biology9090261 Authors: Cíntia Helena Duarte Sagawa Paulo A. Zaini Renata de A. B. Assis Houston Saxe Michelle Salemi Aaron Jacobson Phillip A. Wilmarth Brett S. Phinney Abhaya M. Dandekar Plant secretome studies highlight the importance of vascular plant defense proteins against...
Tue Sep 01, 2020 03:00
Biology, Vol. 9, Pages 262: Relationship of Seminal Oxidation-Reduction Potential with Sperm DNA Integrity and pH in Idiopathic Infertile Patients Biology doi: 10.3390/biology9090262 Authors: Sergio Garcia-Segura Jordi Ribas-Maynou Sandra Lara-Cerrillo Agustín Garcia-Peiró Ana Belén Castel Jordi Benet Maria Oliver-Bonet Seminal oxidative stress (OS) is one of the most promising factors to describe the causes of idiopathic male infertility. Redox balance is essential...
Tue Sep 01, 2020 03:00
Biology, Vol. 9, Pages 263: Insights into the Complement System of Tunicates: C3a/C5aR of the Colonial Ascidian Botryllus schlosseri Biology doi: 10.3390/biology9090263 Authors: Anna Peronato Nicola Franchi Loriano Ballarin As an evolutionary ancient component of the metazoan immune defense toolkit, the complement system can modulate cells and humoral responses of both innate and (in jawed vertebrates) adaptive immunity. All the three known complement-activation pathways converge...
Tue Sep 01, 2020 03:00
Biology, Vol. 9, Pages 260: Computational and Transcriptome Analyses Revealed Preferential Induction of Chemotaxis and Lipid Synthesis by SARS-CoV-2 Biology doi: 10.3390/biology9090260 Authors: Hibah Shaath Nehad M. Alajez The continuous and rapid emergence of new viral strains calls for a better understanding of the fundamental changes occurring within the host cell upon viral infection. In this study, we analyzed RNA-seq transcriptome data from Calu-3 human lung epithelial cells...
Tue Sep 01, 2020 03:00
Biomedicines, Vol. 8, Pages 323: Lactoferrin-Derived Peptides as a Control Strategy against Skinborne Staphylococcal Biofilms Biomedicines doi: 10.3390/biomedicines8090323 Authors: Laura Quintieri Leonardo Caputo Linda Monaci Maria Maddalena Cavalluzzi Nunzio Denora Coagulase-negative staphylococci (CoNS) widely colonize the human skin and play an active role in host defense. However, these bacteria may cause malodours and increase infection incidence rate in immune-compromised...
Tue Sep 01, 2020 03:00
Biomedicines, Vol. 8, Pages 322: Up- or Downregulation of Melanin Synthesis Using Amino Acids, Peptides, and Their Analogs Biomedicines doi: 10.3390/biomedicines8090322 Authors: Yong Chool Boo Harmonious synthesis and distribution of melanin in the skin contribute to the expression of beauty and the maintenance of health. When skin pigmentary disorders occur because of internal or external factors or, when there is a need to artificially increase or reduce the pigmentation level of the...
Tue Sep 01, 2020 03:00
Biomolecules, Vol. 10, Pages 1261: Implication of Potassium Channels in the Pathophysiology of Pulmonary Arterial Hypertension Biomolecules doi: 10.3390/biom10091261 Authors: Hélène Le Ribeuz Véronique Capuano Barbara Girerd Marc Humbert David Montani Fabrice Antigny Pulmonary arterial hypertension (PAH) is a rare and severe cardiopulmonary disease without curative treatments. PAH is a multifactorial disease that involves genetic predisposition, epigenetic factors, and...
Tue Sep 01, 2020 03:00
Biosensors, Vol. 10, Pages 112: Biosensors for Antioxidants Detection: Trends and Perspectives Biosensors doi: 10.3390/bios10090112 Authors: Melinda David Monica Florescu Camelia Bala Herein we review the recent advances in biosensors for antioxidants detection underlying principles particularly emphasizing advantages along with limitations regarding the ability to discriminate between the specific antioxidant or total content. Recent advances in both direct detection of antioxidants,...
Tue Sep 01, 2020 03:00
Biosensors, Vol. 10, Pages 113: Enhancement of the Peroxidase-Like Activity of Iodine-Capped Gold Nanoparticles for the Colorimetric Detection of Biothiols Biosensors doi: 10.3390/bios10090113 Authors: Chia-Chen Chang Tsz-Lian Hsu Chie-Pein Chen Chen-Yu Chen A colorimetric assay was developed for the detection of biothiols, based on the peroxidase-like activity of iodine-capped gold nanoparticles (AuNPs). These AuNPs show a synergetic effect in the form of peroxidase-mimicking...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2483: Lenalidomide in Combination with Arsenic Trioxide: an Effective Therapy for Primary Effusion Lymphoma Cancers doi: 10.3390/cancers12092483 Authors: Sara Moodad Rana El Hajj Rita Hleihel Layal Hajjar Nadim Tawil Martin Karam Maguy Hamie Raghida Abou Merhi Marwan El Sabban Hiba El Hajj Primary effusion lymphoma (PEL) is a rare aggressive subset of non-Hodgkin B cell lymphoma. PEL is secondary to Kaposi sarcoma herpes virus (KSHV)...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2482: Counteracting Chemoresistance with Metformin in Breast Cancers: Targeting Cancer Stem Cells Cancers doi: 10.3390/cancers12092482 Authors: Samuel Varghese Koklesová Líšková Kubatka Büsselberg Despite the leaps and bounds in achieving success in the management and treatment of breast cancers through surgery, chemotherapy, and radiotherapy, breast cancer remains the most frequently occurring cancer in women and the most common cause of...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2478: Genotype of Null Polymorphisms in Genes GSTM1, GSTT1, CYP1A1, and CYP1A1*2A (rs4646903 T>C)/CYP1A1*2C (rs1048943 A>G) in Patients with Larynx Cancer in Southeast Spain Cancers doi: 10.3390/cancers12092478 Authors: Mariano Sánchez-Siles Juan Pablo Pelegrín-Hernández Diego Hellin-Meseguer Yolanda Guerrero-Sánchez Andrés Corno-Caparrós Juan Cabezas-Herrera Francisco Pastor-Quirante José Alberto Fernández-Ruiz Alfonso Aliaga-Sánchez Mayra...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2481: Entosis: From Cell Biology to Clinical Cancer Pathology Cancers doi: 10.3390/cancers12092481 Authors: Izabela Mlynarczuk-Bialy Ireneusz Dziuba Agnieszka Sarnecka Emilia Platos Magdalena Kowalczyk Katarzyna K. Pels Grzegorz M. Wilczynski Cezary Wojcik Lukasz P. Bialy Entosis is a phenomenon, in which one cell enters a second one. New clinico-histopathological studies of entosis prompted us to summarize its significance in cancer. It...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2480: CDK4/6 Inhibitors in Hormone Receptor-Positive Metastatic Breast Cancer: Current Practice and Knowledge Cancers doi: 10.3390/cancers12092480 Authors: Debora de Melo Gagliato Antonio C Buzaid Jose Manuel Perez-Garcia Antonio Llombart Javier Cortes Treatment paradigms in advanced hormone receptor (HR)-positive breast cancer were substantially transformed with cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) approval. The addition of these drugs...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2479: Targeting Signaling Pathways in Inflammatory Breast Cancer Cancers doi: 10.3390/cancers12092479 Authors: Xiaoping Wang Takashi Semba Lan Thi Hanh Phi Sudpreeda Chainitikun Toshiaki Iwase Bora Lim Naoto T. Ueno Inflammatory breast cancer (IBC), although rare, is the most aggressive type of breast cancer. Only 2–4% of breast cancer cases are classified as IBC, but—owing to its high rate of metastasis and poor prognosis—8%...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2477: ATP Production Relies on Fatty Acid Oxidation Rather than Glycolysis in Pancreatic Ductal Adenocarcinoma Cancers doi: 10.3390/cancers12092477 Authors: Jae-Seon Lee Su-Jin Oh Hyun-Jung Choi Joon Hee Kang Seon-Hyeong Lee Ji Sun Ha Sang Myung Woo Hyonchol Jang Ho Lee Soo-Youl Kim Glycolysis is known as the main pathway for ATP production in cancer cells. However, in cancer cells, glucose deprivation for 24 h does not reduce ATP levels,...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2473: Critical Role for Cold Shock Protein YB-1 in Cytokinesis Cancers doi: 10.3390/cancers12092473 Authors: Sunali Mehta Michael Algie Tariq Al-Jabry Cushla McKinney Srinivasaraghavan Kannan Chandra S Verma Weini Ma Jessie Zhang Tara K. Bartolec V. Pragathi Masamsetti Kim Parker Luke Henderson Maree L Gould Puja Bhatia Rhodri Harfoot Megan Chircop Torsten Kleffmann Scott B Cohen Adele G Woolley Anthony J Cesare...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2475: Flavokawain B and Doxorubicin Work Synergistically to Impede the Propagation of Gastric Cancer Cells via ROS-Mediated Apoptosis and Autophagy Pathways Cancers doi: 10.3390/cancers12092475 Authors: You-Cheng Hseu Ruei-Wan Lin Yi-Chun Shen Kai-Yuan Lin Jiunn-Wang Liao Varadharajan Thiyagarajan Hsin-Ling Yang Chalcone flavokawain B (FKB) possesses a chemopreventive and anti-cancer activity. Doxorubicin is a chemotherapeutic DNA intercalating...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2474: Identification of Clinical and Socioeconomic Predictors of Adjuvant Therapy after Trans-Oral Robotic Surgery in Patients with Oropharyngeal Squamous Cell Carcinoma Cancers doi: 10.3390/cancers12092474 Authors: Sujith Baliga Brett Klamer Sachin Jhawar Mauricio Gamez Darrion Mitchell Adriana Blakaj John Grecula Ulysses Gardner Khaled Dibs Matthew Old Nolan Seim Stephen Kang Ricardo Carrau Amit Agrawal Vidhya Karivedu Priyanka...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2476: Cancer-Specific Immune Prognostic Signature in Solid Tumors and Its Relation to Immune Checkpoint Therapies Cancers doi: 10.3390/cancers12092476 Authors: Shaoli Das Kevin Camphausen Uma Shankavaram To elucidate the role of immune cell infiltration as a prognostic signature in solid tumors, we analyzed immune-function-related genes from four publicly available single-cell RNA-Seq data sets and twenty bulk tumor RNA-Seq data sets from The Cancer Genome...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2471: Clinical Studies Applying Cytokine-Induced Killer Cells for the Treatment of Renal Cell Carcinoma Cancers doi: 10.3390/cancers12092471 Authors: Ying Zhang Jörg Ellinger Manuel Ritter Ingo G. H. Schmidt-Wolf There is growing interest in cytokine-induced killer (CIK) cells on the integrated therapy of patients with RCC, especially those in the late stage or refractory to conventional chemotherapy and radiotherapy. In this review, a total of 15 clinical...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2470: Revisiting the Concept of Stress in the Prognosis of Solid Tumors: A Role for Stress Granules Proteins? Cancers doi: 10.3390/cancers12092470 Authors: Anaïs Aulas Pascal Finetti Shawn M. Lyons François Bertucci Daniel Birnbaum Claire Acquaviva Emilie Mamessier Cancer treatments are constantly evolving with new approaches to improve patient outcomes. Despite progresses, too many patients remain refractory to treatment due to either the development...
Tue Sep 01, 2020 03:00
Cancers, Vol. 12, Pages 2472: Intronic TP53 Polymorphisms Are Associated with Increased Δ133TP53 Transcript, Immune Infiltration and Cancer Risk Cancers doi: 10.3390/cancers12092472 Authors: Ramona A. Eiholzer Sunali Mehta Marina Kazantseva Catherine J. Drummond Cushla McKinney Katie Young David Slater Brianna C. Morten Kelly A. Avery-Kiejda Annette Lasham Nicholas Fleming Helen R. Morrin Karen Reader Janice A. Royds Michael Landmann Simone Petrich...
Tue Sep 01, 2020 03:00
Cells, Vol. 9, Pages 2013: Targeting Oxidative Phosphorylation Reverses Drug Resistance in Cancer Cells by Blocking Autophagy Recycling Cells doi: 10.3390/cells9092013 Authors: Jae-Seon Lee Ho Lee Hyonchol Jang Sang Myung Woo Jong Bae Park Seon-Hyeong Lee Joon Hee Kang Hee Yeon Kim Jaewhan Song Soo-Youl Kim The greatest challenge in cancer therapy is posed by drug-resistant recurrence following treatment. Anticancer chemotherapy is largely focused on targeting...
Tue Sep 01, 2020 03:00
Cells, Vol. 9, Pages 2012: Senescence Induction by Combined Ionizing Radiation and DNA Damage Response Inhibitors in Head and Neck Squamous Cell Carcinoma Cells Cells doi: 10.3390/cells9092012 Authors: Clara Dobler Tina Jost Markus Hecht Rainer Fietkau Luitpold Distel DNA damage response inhibitors (DDRi) may selectively enhance the inactivation of tumor cells in combination with ionizing radiation (IR). The induction of senescence may be the key mechanism of tumor cell inactivation...
Tue Sep 01, 2020 03:00
Cells, Vol. 9, Pages 2014: A Translational Mouse Model for NASH with Advanced Fibrosis and Atherosclerosis Expressing Key Pathways of Human Pathology Cells doi: 10.3390/cells9092014 Authors: Anita M. van den Hoek Lars Verschuren Nicole Worms Anita van Nieuwkoop Christa de Ruiter Joline Attema Aswin L. Menke Martien P. M. Caspers Sridhar Radhakrishnan Kanita Salic Robert Kleemann Non-alcoholic steatohepatitis (NASH) is a fast-growing liver disorder that is...
Tue Sep 01, 2020 03:00
Cells, Vol. 9, Pages 2010: The E3 Ubiquitin-Protein Ligase Cullin 3 Regulates HIV-1 Transcription Cells doi: 10.3390/cells9092010 Authors: Simon Langer Xin Yin Arturo Diaz Alex J. Portillo David E. Gordon Umu H. Rogers John M. Marlett Nevan J. Krogan John A. T. Young Lars Pache Sumit K. Chanda The infectious life cycle of the human immunodeficiency virus type 1 (HIV-1) is characterized by an ongoing battle between a compendium of cellular proteins that either...
Tue Sep 01, 2020 03:00
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