Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThe aim of our study was to explore the association between serum cystatin C (CysC) and euthyroid Hashimoto’s thyroiditis.MethodsThere were 119 female euthyroid Hashimoto’s thyroiditis patients and 225 healthy controls who were recruited. Serum CysC, thyroid function, thyroid autoantibodies, fasting glucose, liver enzymes, and lipid profile were determined. Clinical parameters were compared between two groups.ResultsSerum...
Tue Sep 01, 2020 11:23
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveIn this meta-analysis, we aimed to evaluate the oncological outcomes of preoperative neoadjuvant chemotherapy followed by radical surgery compared with radical surgery alone for treatment of International Federation of Gynecology and Obstetrics (FIGO) stage I–II cervical cancer.MethodWe searched for studies comparing the safety and efficacy of neoadjuvant chemotherapy plus surgery versus surgery alone in treatment...
Tue Sep 01, 2020 11:23
Journal of International Medical Research, Volume 48, Issue 8, August 2020. We report a case of a Chinese neonate who was diagnosed with Noonan syndrome and had persistent, self-limited thrombocytopenia. The neonate was admitted to the Neonatology Department 20 minutes after birth because of respiratory distress. From birth until 2 months of age, platelet values fluctuated between approximately 6 and 30 × 109/L. There was no intracranial hemorrhage. However, the child had a transient hypocalcemic...
Tue Sep 01, 2020 11:23
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo assess the clinical outcomes of hemi-shoulder arthroplasty (HSA) versus reverse total shoulder arthroplasty (RTSA) following failed plate osteosynthesis of proximal humerus fractures in elderly patients.MethodsThis retrospective study identified all patients that had a documented failed plate osteosynthesis of proximal humeral fractures treated with revision HSA or RTSA. Follow-up occurred at 1, 3, 6 and 12 months...
Tue Sep 01, 2020 11:23
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Branchial fistulas are uncommon in the clinical setting. The coexistence of first and second branchial fistulas has not been previously reported. We herein describe a 12-year-old girl who presented with a 2-year history of repeated swelling and purulence behind the right earlobe and neck. According to the patient’s physical and auxiliary examination findings, she was diagnosed with coexisting first and second branchial fistulas,...
Mon Aug 31, 2020 13:11
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Infarcted regenerative nodules in a cirrhotic liver is a rare condition that may be confused with hepatocellular carcinoma on imaging. We report here a case of a 58-year-old man with live cirrhosis who presented with abdominal pain and distension and sudden onset of haematemesis. Computed tomography (CT) showed diffuse multinodular infarcted regenerative nodules and gastric bleeding. Physicians should include infarcted regenerative...
Mon Aug 31, 2020 13:09
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study was performed to explore the relationship between various clinical factors and the prognosis of limb osteosarcoma.MethodsWe retrospectively analyzed the clinical data of 336 patients with limb osteosarcoma treated from June 2000 to August 2016 at 7 Chinese cancer centers. Data on the patients’ clinical condition, treatment method, complications, recurrences, metastasis, and prognosis were collected and...
Mon Aug 31, 2020 13:08
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Gastric bezoars are foreign bodies that occur when certain drugs or foods aggregate in the stomach. They cannot be digested and most are unable to pass through the pylorus. Here, we describe a giant hard gastric bezoar that was removed by using combined dual knife–electric snare treatment. This strategy has rarely been reported and can eliminate the need for surgery. The patient exhibited a giant hard gastric bezoar and reported...
Mon Aug 31, 2020 13:06
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveWe investigated physical deviation and precocious puberty among school-aged children in Leshan City, to provide a theoretical basis for the management of precocious puberty in children.MethodsWe selected 12 primary schools of Leshan City using a cluster random sampling method and conducted physical examinations among healthy students aged 4 12 years. A total of 11,000 students were recruited (5502 boys and 5498 girls)....
Mon Aug 31, 2020 12:59
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveCranial electrotherapy stimulation (CES) is a non-invasive treatment that improves symptoms such as anxiety and pain. The purpose of this study was to analyze the effect of CES pretreatment on levels of preoperative anxiety, pain, and hemodynamic responses—especially changes in blood pressure—during anesthetic induction in patients with essential hypertension.MethodsEighty patients undergoing general anesthesia were...
Mon Aug 31, 2020 12:58
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Vanishing bile duct syndrome (VBDS) refers to a group of acquired disorders associated with progressive destruction and disappearance of the intrahepatic bile ducts. We report a case of meropenem-induced VBDS in a patient who had undergone surgical repair of a ruptured abdominal aortic aneurysm. Meropenem was used to treat Serratia marcescens isolated from blood, urine, sputum, and wound swab cultures. The patient developed...
Mon Aug 31, 2020 12:55
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveClinical characteristics of patients with pyogenic liver abscess (PLA) of varying etiologies may be different. This study aimed to analyze the clinical characteristics, pathogenic bacteria, treatment, and prognosis of patients with PLA associated with diabetes and biliary disease.MethodsClinical, imaging, and laboratory data from 202 inpatients with PLA were retrospectively analyzed.ResultsEighty-eight patients (43.6%)...
Mon Aug 31, 2020 12:53
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Tumors of the parapharyngeal space (PPS) are rare, most originate from salivary and neurogenic tissues, and most are benign. However, there are some rarer masses in the PPS, with just a few published reports in the literature worldwide, and we may not consider them in the differential diagnosis of PPS neoplasms. We report three cases of rare masses in the PPS: Warthin’s tumor, branchial cleft cyst, and carcinoma ex pleomorphic...
Mon Aug 31, 2020 12:51
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveComplications frequently occur in patients with breast cancer after surgery. Anesthesia nursing plays an important role in decreasing complications for such patients. Thus, this study investigated the effects of anesthesia with intensive care nursing (AICN) on complication rates in patients with breast cancer after surgery.MethodsEighty-two patients with breast cancer were recruited in this study. Complications were...
Mon Aug 31, 2020 12:49
Journal of International Medical Research, Volume 48, Issue 8, August 2020. BackgroundThe outbreak of coronavirus disease 2019 (COVID-19) began in December 2019 and continues to spread worldwide. Rapid and accurate identification of suspected cases is critical in slowing spread of the virus that causes the disease. We aimed to highlight discrepancies in the various criteria used by international agencies and highly impacted individual countries around the world.MethodsWe reviewed the criteria for...
Mon Aug 31, 2020 12:48
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectivesTo assess the effects of zinc pretreatment on hepatorenal toxicity following chronic exposure to glyphosate-based herbicides in male rats.MethodsFollowing zinc pretreatment (50 mg/kg and 100 mg/kg), 14.4 to 750 mg/kg of oral glyphosate (Bushfire® herbicide) was administered daily for 36 weeks. Thereafter, serum samples were obtained following jugular venipuncture. Liver and kidney samples were processed for histopathological...
Mon Aug 31, 2020 12:45
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis study was performed to investigate the clinical characteristics of patients with coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).MethodsWe analyzed the electronic medical records of 405 hospitalized patients with laboratory-confirmed COVID-19 in the Third Hospital of Wuhan.ResultsThe patients’ median age was 56 years, 54.1% were female, 11.4%...
Mon Aug 31, 2020 12:42
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Spontaneous epistaxis in patients with COVID-19 can represent a clinical challenge with respect to both the risk of contamination and the treatment options. We herein present the data of 30 patients with COVID-19 who developed spontaneous epistaxis while hospitalized at Eastern Piedmont Hospital during March and April 2020. All patients received low-molecular-weight heparin during their hospital stay and required supplementary...
Mon Aug 31, 2020 12:40
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo identify the risk factors for early death and determine the predictive value of the sequential organ failure assessment (SOFA) score for prognosis of severe acute ischemic stroke (AIS).MethodsA total of 110 patients with severe AIS were enrolled and divided into the non-survivor (n = 34) and survivor groups (n = 76). Logistic regression analysis was conducted to identify risk factors for early death, while the...
Mon Aug 31, 2020 12:37
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectivesThe inhibition of pyroptosis has a protective effect in sepsis-associated encephalopathy (SAE). However, the mechanisms underlying pyroptosis in SAE remain to be elucidated.MethodsHere, we investigated the effects of the caspase inhibitors, Belnacasan (Beln) and Wedelolactone (Wede), on an induced model of SAE in P12 cells, using immunofluorescence, ELISA, western blotting, and flow cytometry.ResultsThe cell viability...
Mon Aug 31, 2020 12:22
Journal of International Medical Research, Volume 48, Issue 8, August 2020. Tubal diseases are responsible for 25% to 35% of female infertility. Laparoscopic chromopertubation is the gold standard for assessing tubal patency when female infertility is suspected. Intravasation is a complication of intrauterine procedures involving the passage of fluid filling the uterine cavity into the bloodstream through endometrial vessels (from the myometrial veins to the uterine venous plexuses). This complication...
Mon Aug 31, 2020 12:21
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveExcessive inflammatory responses in the endocardium are related to progression of infectious endocarditis. This study aimed to investigate whether (Z)-7,4'-dimethoxy-6-hydroxy-aurone-4-O-β-glucopyranoside (DHAG), a compound isolated from the endophytic fungus Penicillium citrinum of Bruguiera gymnorrhiza, could attenuate cell damage caused by lipoteichoic acid (LTA) in embryonic rat heart cells (H9c2).MethodsLTA-induced...
Mon Aug 31, 2020 12:18
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveOur objective was to investigate the association between anastomotic leakage (AL) and hyponatremia after colorectal cancer surgery.MethodsAll anastomoses in colorectal cancer surgery performed in our hospital between January 2015 and December 2017 were retrospectively identified. According to the diagnostic criteria of AL, the patients were divided into an AL group and a no anastomotic leakage (NAL) group.ResultsWe...
Mon Aug 31, 2020 12:15
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveThis prospective study aimed to establish the valproic acid (VPA) population pharmacokinetic model in Chinese patients and realise personalised medication on the basis of population pharmacokinetics.MethodsThe patients’ clinical information and VPA plasma concentrations were collected from The General Hospital of Taiyuan Iron & Steel (Group) Corporation (TISCO). Nonlinear mixed-effect modelling was used to build...
Mon Aug 31, 2020 12:12
Journal of International Medical Research, Volume 48, Issue 8, August 2020. A 48-year-old woman was admitted to our hospital with a lump in her left breast. She was diagnosed with synchronous papillary thyroid carcinoma and breast ductal carcinoma. The patient underwent four cycles of neoadjuvant chemotherapy with epirubicin and cyclophosphamide, and one cycle of docetaxel. She then underwent left breast mastectomy and radical resection of thyroid cancer (total thyroidectomy and bilateral central...
Mon Aug 31, 2020 12:09
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveCisplatin (CDDP) toxicity is a dose-limiting clinical problem in clinical practice, mainly because of nephrotoxicity or ototoxicity. However, the mechanism of CDDP-induced cardiotoxicity is poorly understood. Acetyl-l-carnitine (ALCAR) is an antioxidant agent with protective effects against the side effects of various chemotherapeutics. CDDP-induced cardiotoxicity and the protective role of ALCAR were evaluated in...
Mon Aug 31, 2020 12:05
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveSelf-management is beneficial for improving health outcomes in adults with type 1 diabetes. However, there are no validated instruments to assess self-management in Chinese adults with type 1 diabetes. The aim of this study was to develop and validate the Self-Management of Type 1 Diabetes for Chinese Adults (SMOD-CA) scale.MethodsQualitative and quantitative methods were used to develop the SMOD-CA.We conducted...
Mon Aug 31, 2020 12:00
Journal of International Medical Research, Volume 48, Issue 8, August 2020. ObjectiveTo investigate the characteristics of the macrophage response to transfusion of erythrocytes kept at different storage times in the mouse model of haemorrhagic shock.MethodsErythrocytes were isolated from mice and stored for 7, 21 or 35 days and samples injected intravenously into haemorrhagic shock mice. Changes in macrophages, inflammatory cytokines and T cell differentiation were assessed using flow cytometry...
Mon Aug 31, 2020 11:57
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