Roderico H Ofrin, Anil K Bhola, Nilesh BuddhaWHO South-East Asia Journal of Public Health 2020 9(1):5-14 Emergency preparedness is a continuous process in which risk and vulnerability assessments, planning and implementation, funding, partnerships and political commitment at all levels must be sustained and acted upon. It relates to health systems strengthening, disaster risk reduction and operational readiness to respond to emergencies. Strategic interventions to strengthen the capacities of countries...
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Gyanendra Gongal, Roderico H OfrinWHO South-East Asia Journal of Public Health 2020 9(1):50-51 The Asia-Pacific region is vulnerable to a wide range of emergencies and natural disasters that are becoming more frequent because of seismic activity, climate change and changes in human development. For the rural poor in low-income settings, animals are valued beyond their financial worth as a fundamental part of human existence and livelihoods. Despite this recognition, animals are rarely included...
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Roderico H Ofrin, Nilesh Buddha, Maung Maung Htike, Anil K Bhola, Supriya BezbaruahWHO South-East Asia Journal of Public Health 2020 9(1):15-20 Risk communication and community engagement are critical aspects of public health emergency preparedness and response and therefore one of the eight original core capacities of the International Health Regulations (2005). Joint external evaluations in eight out of eleven countries of the World Health Organization South-East Asia Region reveal that there...
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Mark Goodchild, Praveen Sinha, Vineet Gill Munish, Fikru Tesfaye TulluWHO South-East Asia Journal of Public Health 2020 9(1):73-81 Background Increasing the price of tobacco through taxation is a very effective means of reducing tobacco use. However, the impact of price increases can be diluted if consumer incomes are growing strongly. The affordability of tobacco products has, therefore, become an important indicator for tobacco control. This study asks whether tobacco products in India became...
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Gyanendra Gongal, Roderico H Ofrin, Katinka de Balogh, Yooni Oh, Hirofumi Kugita, Kinzang DukpaWHO South-East Asia Journal of Public Health 2020 9(1):21-25 One Health refers to the collaborative efforts of multiple disciplines working locally, nationally and globally to attain optimal health for people, animals and our environment. The One Health approach is increasingly popular in the context of growing threats from emerging zoonoses, antimicrobial resistance and climate change. The Food and Agriculture...
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Pushpa R Wijesinghe, Roderico H Ofrin, Anil K Bhola, Francis Y Inbanathan, Supriya BezbaruahWHO South-East Asia Journal of Public Health 2020 9(1):43-49 Pandemic influenza preparedness has contributed significantly to building, strengthening and maintaining countries’ core capacities to prepare for health emergencies. The Pandemic influenza preparedness framework for the sharing of influenza viruses and access to vaccines and other benefits (the PIP framework) was adopted by the World Health Assembly...
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Nyoman Kumara Rai, Kwang Il Rim, Endang Widuri Wulandari, Frieda Subrata, Anung Sugihantono, Vensya SitohangWHO South-East Asia Journal of Public Health 2020 9(1):26-31 Indonesia has made excellent progress on emergency preparedness in compliance with the International Health Regulations, 2005, including a joint external evaluation (JEE) of IHR core capacities in 2017. Development of the National action plan for health security (NAPHS) began soon after the JEE, through multisectoral coordination...
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Lluís Vinyals Torres, Valeria de Oliveira Cruz, Xavier Modol, Phyllida TravisWHO South-East Asia Journal of Public Health 2020 9(1):52-54 Basic packages of health services (BPHSs) are often envisaged primarily as political statements of intent to provide access to care, in an era of commitment to universal health coverage. They are often produced with little attention paid to health systems’ capacity to deliver these benefit packages or other implementation challenges. Many countries of the World...
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Kai von Harbou, Narumol Sawanpanyalert, Abigail Trewin, Richard Brown, John Prawira, Anil K Bhola, Arturo Pesigan, Roderico H OfrinWHO South-East Asia Journal of Public Health 2020 9(1):32-36 The World Health Organization (WHO) emergency medical team (EMT) mentorship and verification process is an important mechanism for providing quality assurance for EMTs that are deployed internationally during medical emergencies. To be recommended for classification, an organization must demonstrate compliance...
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Novil W A N Y Wijesekara, Asanka Wedamulla, Sugandhika Perera, Arturo Pesigan, Roderico H OfrinWHO South-East Asia Journal of Public Health 2020 9(1):66-72 Background Drought is an extreme weather event. Drought-related health effects can increase demands on hospitals while restricting their functional capacity. In July 2017, Sri Lanka had been experiencing prolonged drought for around a year and data on the resilience of hospitals were required. Methods A cross-sectional survey was done in five...
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Arturo Pesigan, Anil K Bhola, Hyon C Pak, Sugandhika Perera, John Prawira, Kai von Harbou, Sourabh K Sinha, Nilesh Buddha, Tamara Curtin Niemi, Egmond Evers, Roderico H OfrinWHO South-East Asia Journal of Public Health 2020 9(1):37-42 The World Health Organization (WHO) has an essential role to play in supporting Member States to prepare for, respond to and recover from emergencies with public health consequences. Operational readiness for known and unknown hazards and emergencies requires a risk-informed...
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Chandrakant Lahariya, Bijit Roy, Abhay Shukla, Mirai Chatterjee, Hilde De Graeve, Manoj Jhalani, Henk BekedamWHO South-East Asia Journal of Public Health 2020 9(1):82-91 The role of civil society and community-based organizations in advancing universal health coverage and meeting the targets of the 2030 Agenda for Sustainable Development has received renewed recognition from major global initiatives. This article documents the evolution and lessons learnt through two decades of experience in India...
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Abstract The influence of peripheral blood stem cell (PBSC) graft cell contents after transplant with post-transplant cyclophosphamide (PTCY) remains unclear. Here, we retrospectively report on a cohort of 77 adults who received a Baltimore-based reduced-intensity conditioning regimen either with fludarabine (n = 40) or clofarabine (n = 37) and PTCY. With a median follow-up of 29.2 months, [2-]year overall (OS), disease-free (DFS), and GVHD/relapse-free survival (GRFS) rates were...
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Abstract In everyday gynecological practice, there is an unmet need to manage survivors after allogeneic hematopoietic cell transplantation (allo-HCT). The major gynecological complications include premature ovarian insufficiency (POI), chronic graft-versus-host disease (cGVHD) of the anogenital zone (cGVHDgyn), and secondary neoplasms. Aiming to assess a real-life scale of problems associated with HCT, we performed a detailed analysis of a consecutive series of females after allo-HCT...
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Abstract Learning techniques have proven their capacity to treat large amount of data. Most statistical learning approaches use specific size learning sets and create static models. Withal, in certain some situations such as incremental or active learning the learning process can work with only a smal amount of data. In this case, the search for algorithms capable of producing models with only a few examples begin to be necessary. Generally, the literature relative to classifiers...
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Abstract Background JCOG0909 is a phase II trial of definitive chemoradiotherapy including salvage treatment for cStage II–III thoracic esophageal cancer; the radiation field for elective regional lymph node irradiation, which can affect patient outcome and adverse event, varied based on the primary tumor site, i.e., upper (Ut), middle (Mt), and lower thoracic (Lt) esophagus. The impact of different primary sites on the safety and efficacy...
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Maternal depression can influence the early activity of a mother reading stories to a young child, as depressed mothers are less likely to read to their children. Here, maternal depression association to neuro...
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Abstract Purpose of Review Cardiovascular diseases (CVDs) and diabetes are the primary causes of death in the Philippines. This manuscript reviewed previous studies on the use of predictive analytics for CVD and diabetes risk scoring. This paper also discussed barriers and strategies on how to access/generate available data sets for CVDs and diabetes in the country. Recent...
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Abstract The aim of this study was to determine the potential impact of the Pediatric Emergency Care Applied Research Network (PECARN) rules on the CT rate in a large paediatric minor traumatic head injury (MTHI) cohort and compare this with current national Dutch guidelines. This was a planned sub-study of a prospective multicentre observational study that enrolled 1006 children younger than 18 years with MTHI. We calculated the number of recommended CT scans and described trauma-related...
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Globally, gastroesophageal adenocarcinoma are among the most common causes of cancer related deaths.1 Treatment still largely relies on conventional cytotoxic agents which are only limitedly effective in the majority of patients.2,3 According to a comprehensive molecular analysis by The Cancer Genome Atlas (TCGA) Network, gastric cancer (including gastroesophageal junction cancer) can be classified into four subgroups based on its molecular characteristics: Epstein-Barr virus (EBV)-infected tumors,...
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Prenatal intake of alcohol and tobacco have been associated with negative outcomes in children. Consumption of alcohol while breastfeeding has also been associated with dose-dependent decreases in abstract rea...
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We noticed that syphilis patients seem to be more susceptible to diabetes and the lesions often involve the kidneys, but the pathogenesis is not yet completely understood. In this study, microarray analysis wa...
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The geometry and stiffness of a vessel are pertinent to blood dynamics and vessel wall mechanical behavior and may alter in diseased conditions. Ultrasound-based ultrafast Doppler (uDoppler) imaging and shear wave imaging (SWI) techniques have been extensively exploited for the assessment of vascular hemodynamics and mechanics. Their performance is conventionally validated on vessel-mimicking phantoms (VMPs) prior to their clinical use. Compared with commercial ones, customized VMPs are...
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Abstract Coronavirus disease 2019 is an infectious disease caused by severe acute respiratory syndrome coronavirus 2. It has taken a toll of lots of lives since its outbreak. Infection prevention at present is an appropriate control measure in addition to other measure like hand hygiene and personal protective equipment (PPE). In our country with a large population, supplying PPE to all the health care workers of all hospitals definitely is an economic burden. Hence we have come...
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Abstract Recurrent aphthous stomatitis (RAS) is a frequently seen oral ulcerative lesion, manifesting as multiple, recurrent, shallow, irregular ulcers encircled by an erythematous halo. The precise etiopathogenesis is obscure, although the recent understanding suggests an underlying immune-mediated etiology. However, there is no defined management protocol and the principal therapy aims to attain symptomatic respite. 150 clinically diagnosed RAS patients of both sexes in the...
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Abstract To achieve improved drug delivery efficiency to hepatocellular carcinoma (HCC), biodegradable poly (ethylene glycol)-poly (lactic-co-glycolic acid) (PEG-PLGA) nanoparticles (NP), surface-modified with SP94 peptide, were designed for the efficient delivery of cryptotanshinone to the tumor for the treatment of HCC. Cryptotanshinone NP and SP94-NP were prepared by using nanoprecipitation. The physicochemical and pharmaceutical properties of the NP and SP94-NP were characterized,...
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Abstract Objective We aimed to investigate the usefulness of glucose administration for maintaining perioperative glycemic control in patients with dietary restrictions during 4 h prior to impacted mandibular third molar extraction under intravenous sedation. Methods Fifty-four individuals scheduled to undergo extraction of impacted mandibular third molars...
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Purpose: To assess early outcomes of corneal neurotization for postherpetic neurotrophic keratopathy (NK). Methods: Retrospective analysis of patients who underwent corneal neurotization for postherpetic NK by a single experienced oculoplastic surgeon was performed. Collected data included stage and etiology of NK as well as comorbidities, prior treatment history, neurotization technique, donor nerve site, preoperative and postoperative examination findings (i.e., ocular surface quality,...
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A 22-year-old woman presented with an acute compressive optic neuropathy due to a ruptured ethmoido-orbital mucocele. She underwent urgent orbital decompression and drainage of the mucocele via an endoscopic approach. Postoperatively, her course was complicated by an orbital compartment syndrome supervened, exhibiting severe eyelid edema caused by infiltration with mucin and mucin-containing macrophages (“muciphages”). Biopsy of the eyelid showed infiltration with “muciphages,” macrophages laden...
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Eyelid metastases are relatively rare, and they can occasionally lead the way to an unknown primary malignancy elsewhere. The authors report a case of 65-year-old diabetic gentleman with a right-sided eyelid lesion that was present for 1 month and turned out to be a presenting sign of a previously undiagnosed pancreatic adenocarcinoma. The eyelid mass had been treated elsewhere for 2 weeks for a presumed infectious lesion, using systemic antibiotics and was then referred to us in view of no response....
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Acute dacryocystitis causing visual loss due to development of orbital complications like central retinal artery or ophthalmic artery occlusion, retinal vein occlusions, and optic neuritis is rare but a known entity. However, development of scleral abscess and panophthalmitis as a complication of acute dacryocystitis, leading to loss of vision, has not been described earlier. To the best of the authors’ knowledge, this is the first report describing this mode of visual loss in acute dacryocystitis. ...
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