Antibiotics, Vol. 9, Pages 215: Prevalence and Antimicrobial Susceptibility Patterns of Bacterial Pathogens in Urinary Tract Infections in University Hospital of Campania “Luigi Vanvitelli” between 2017 and 2018 Antibiotics doi: 10.3390/antibiotics9050215 Authors: Folliero Caputo Rocca Chianese Galdiero Iovene Hay Franci Galdiero Urinary tract infections (UTIs) are the most common and expensive health problem globally. The treatment of UTIs is difficult...
Tue Apr 28, 2020 03:00
Antibiotics, Vol. 9, Pages 214: Plasticity of Coagulase-Negative Staphylococcal Membrane Fatty Acid Composition and Implications for Responses to Antimicrobial Agents Antibiotics doi: 10.3390/antibiotics9050214 Authors: Kiran B. Tiwari Craig Gatto Brian J. Wilkinson Staphylococcus aureus demonstrates considerable membrane lipid plasticity in response to different growth environments, which is of potential relevance to response and resistance to various antimicrobial agents. This...
Tue Apr 28, 2020 03:00
Antibiotics, Vol. 9, Pages 213: Antibacterial Discovery: 21st Century Challenges Antibiotics doi: 10.3390/antibiotics9050213 Authors: Paul S. Hoffman It has been nearly 50 years since the golden age of antibiotic discovery (1945–1975) ended; yet, we still struggle to identify novel drug targets and to deliver new chemical classes of antibiotics to replace those rendered obsolete by drug resistance. Despite herculean efforts utilizing a wide range of antibiotic discovery platform...
Tue Apr 28, 2020 03:00
Antibodies, Vol. 9, Pages 12: A Review of Deep Learning Methods for Antibodies Antibodies doi: 10.3390/antib9020012 Authors: Jordan Graves Jacob Byerly Eduardo Priego Naren Makkapati S. Vince Parish Brenda Medellin Monica Berrondo Driven by its successes across domains such as computer vision and natural language processing, deep learning has recently entered the field of biology by aiding in cellular image classification, finding genomic connections, and advancing...
Tue Apr 28, 2020 03:00
Antioxidants, Vol. 9, Pages 368: Antiproliferative Effect of Bioaccessible Fractions of Four Brassicaceae Microgreens on Human Colon Cancer Cells Linked to Their Phytochemical Composition Antioxidants doi: 10.3390/antiox9050368 Authors: Fuente López-García Máñez Alegría Barberá Cilla The antiproliferative effect of the bioaccessible fractions (BFs) of four hydroponic Brassicaceae microgreens (broccoli, kale, mustard and radish) was evaluated on colon cancer Caco-2...
Tue Apr 28, 2020 03:00
Antioxidants, Vol. 9, Pages 367: N-Acetyl-Cysteine Regenerates Albumin Cys34 by a Thiol-Disulfide Breaking Mechanism: An Explanation of Its Extracellular Antioxidant Activity Antioxidants doi: 10.3390/antiox9050367 Authors: Alessandra Altomare Giovanna Baron Maura Brioschi Martina Longoni Riccardo Butti Edoardo Valvassori Elena Tremoli Marina Carini Piergiuseppe Agostoni Giulio Vistoli Cristina Banfi Giancarlo Aldini In the present paper, the extracellular...
Tue Apr 28, 2020 03:00
Antioxidants, Vol. 9, Pages 366: Anthocyanins and Human Health—A Focus on Oxidative Stress, Inflammation and Disease Antioxidants doi: 10.3390/antiox9050366 Authors: Speer D’Cunha Alexopoulos McKune Naumovski Consumption of anthocyanins (ACNs), due to their antioxidant, anti-inflammatory and anti-apoptotic effects, has been proposed for the prevention and treatment of several different diseases and conditions. ACNs are recognized as one of the leading nutraceuticals...
Tue Apr 28, 2020 03:00
Atmosphere, Vol. 11, Pages 442: Measurement and Prediction of Wind Fields at an Offshore Site by Scanning Doppler LiDAR and WRF Atmosphere doi: 10.3390/atmos11050442 Authors: Jay Prakash Goit Atsushi Yamaguchi Takeshi Ishihara LiDAR-based wind speed measurements have seen a significant increase in interest in wind energy. However, reconstruction of wind speed vector from a LiDAR-measured radial wind speed is still a challenge. Furthermore, for extensive application of LiDAR technology,...
Tue Apr 28, 2020 03:00
Atmosphere, Vol. 11, Pages 443: The Role of Weather Types in Assessing the Rainfall Key Factors for Erosion in Two Different Climatic Regions Atmosphere doi: 10.3390/atmos11050443 Authors: María Fernández-Raga Roberto Fraile Covadonga Palencia Elena Marcos Ana María Castañón Amaya Castro This paper compares two different geographical sites, Aveiro and León, from different climatic regions, oceanic and continental, but which share the same type of weather (according...
Tue Apr 28, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 84: The Role of the Size of the Small Group and Informal Subgroups in Intragroup Conflicts Behavioral Sciences doi: 10.3390/bs10050084 Authors: Andrey V. Sidorenkov Eugene F. Borokhovski This study examines the relationship between (a) the size of groups and the number of informal subgroups in them with conflicts in the context of the group, and (b) the size of the informal subgroups with conflicts in the context of the subgroup. A multidimensional...
Tue Apr 28, 2020 03:00
Bioengineering, Vol. 7, Pages 39: In Vitro Characterization of a Novel Human Acellular Dermal Matrix (BellaCell HD) for Breast Reconstruction Bioengineering doi: 10.3390/bioengineering7020039 Authors: Sun-Young Nam Dayoung Youn Gyeong Hoe Kim Ji Hwa Chai Hyang Ran Lim Hong Hee Jung Chan Yeong Heo In the past, acellular dermal matrices (ADMs) have been used in implant-based breast reconstruction. Various factors affect the clinical performance of ADMs since there is...
Tue Apr 28, 2020 03:00
Biology, Vol. 9, Pages 91: Epigenetic Changes in Host Ribosomal DNA Promoter Induced by an Asymptomatic Plant Virus Infection Biology doi: 10.3390/biology9050091 Authors: Miryam Pérez-Cañamás Elizabeth Hevia Carmen Hernández DNA cytosine methylation is one of the main epigenetic mechanisms in higher eukaryotes and is considered to play a key role in transcriptional gene silencing. In plants, cytosine methylation can occur in all sequence contexts (CG, CHG, and CHH), and its levels...
Tue Apr 28, 2020 03:00
Biomedicines, Vol. 8, Pages 100: Organic Acids from Roselle (Hibiscus sabdariffa L.)—A Brief Review of Its Pharmacological Effects Biomedicines doi: 10.3390/biomedicines8050100 Authors: Jeannett A. Izquierdo-Vega Diego A. Arteaga-Badillo Manuel Sánchez-Gutiérrez José A. Morales-González Nancy Vargas-Mendoza Carlos A. Gómez-Aldapa Javier Castro-Rosas Luis Delgado-Olivares Eduardo Madrigal-Bujaidar Eduardo Madrigal-Santillán Roselle (Hibiscus sabdariffa L.),...
Tue Apr 28, 2020 03:00
Biomimetics, Vol. 5, Pages 17: Daily Application of a Toothpaste with Biomimetic Hydroxyapatite and Its Subjective Impact on Dentin Hypersensitivity, Tooth Smoothness, Tooth Whitening, Gum Bleeding, and Feeling of Freshness Biomimetics doi: 10.3390/biomimetics5020017 Authors: Sonja Steinert Kai Zwanzig Helga Doenges Joern Kuchenbecker Frederic Meyer Joachim Enax The aim of this observational study was to analyze the effect of a toothpaste with biomimetic zinc hydroxyapatite...
Tue Apr 28, 2020 03:00
Biomolecules, Vol. 10, Pages 680: In Silico Analysis of a Highly Mutated Gene in Cancer Provides Insight into Abnormal mRNA Splicing: Splicing Factor 3B Subunit 1K700E Mutant Biomolecules doi: 10.3390/biom10050680 Authors: Asmaa Samy Baris Suzek Mehmet Ozdemir Ozge Sensoy Cancer is the second leading cause of death worldwide. The etiology of the disease has remained elusive, but mutations causing aberrant RNA splicing have been considered one of the significant factors in various...
Tue Apr 28, 2020 03:00
Biomolecules, Vol. 10, Pages 681: Advances in Ginsenosides Biomolecules doi: 10.3390/biom10050681 Authors: Jen-Tsung Chen Ginsenosides are unique to plants that belong to the Panax genus [...]
Tue Apr 28, 2020 03:00
Biomolecules, Vol. 10, Pages 684: Culture and Differentiation of Human Hair Follicle Dermal Papilla Cells in a Soft 3D Self-Assembling Peptide Scaffold Biomolecules doi: 10.3390/biom10050684 Authors: Nausika Betriu Claire Jarrosson-Moral Carlos E. Semino Hair follicle dermal papilla cells (HFDPC) are a specialized cell population located in the bulge of the hair follicle with unique characteristics such as aggregative behavior and the ability to induce new hair follicle formation....
Tue Apr 28, 2020 03:00
Biomolecules, Vol. 10, Pages 682: ADAMTS-15 Has a Tumor Suppressor Role in Prostate Cancer Biomolecules doi: 10.3390/biom10050682 Authors: Marley J. Binder Scott McCoombe Elizabeth D. Williams Daniel R. McCulloch Alister C. Ward Extracellular matrix remodeling has emerged as an important factor in many cancers. Proteoglycans, including versican (VCAN), are regulated via cleavage by the proteolytic actions of A Disintegrin-like And Metalloproteinase domain with Thrombospondin-1...
Tue Apr 28, 2020 03:00
Biomolecules, Vol. 10, Pages 683: TLC-Based Bioassay to Isolate Kairomones from Tea Tree Essential Oil That Attract Male Mediterranean Fruit Flies, Ceratitis capitata (Wiedemann) Biomolecules doi: 10.3390/biom10050683 Authors: Nurhayat Tabanca Jerome Niogret Paul E. Kendra Nancy D. Epsky The Mediterranean fruit fly, Ceratitis capitata (Wiedemann) (Diptera: Tephritidae) poses a major threat to fruit and vegetable production in the United States and throughout the world. New attractants...
Tue Apr 28, 2020 03:00
Biomolecules, Vol. 10, Pages 678: Cord Blood Serum (CBS)-Based Eye Drops Modulate Light-Induced Neurodegeneration in Albino Rat Retinas Biomolecules doi: 10.3390/biom10050678 Authors: Stefano Di Marco Serena Riccitelli Mattia Di Paolo Emilio Campos Marina Buzzi Silvia Bisti Piera Versura Age-related macular degeneration (AMD) is one of the leading causes of visual loss in western countries, it has no cure, and its incidence will grow in the future, for the overall population...
Tue Apr 28, 2020 03:00
Biomolecules, Vol. 10, Pages 679: A Biochemometric Approach for the Identification of In Vitro Anti-Inflammatory Constituents in Masterwort Biomolecules doi: 10.3390/biom10050679 Authors: Julia Zwirchmayr Ulrike Grienke Scarlet Hummelbrunner Jaqueline Seigner Rainer de Martin Verena M. Dirsch Judith M. Rollinger Peucedanum ostruthium (L.) Koch, commonly known as masterwort, has a longstanding history as herbal remedy in the Alpine region of Austria, where the roots...
Tue Apr 28, 2020 03:00
Biomolecules, Vol. 10, Pages 677: D-Aspartate Upregulates DAAM1 Protein Levels in the Rat Testis and Induces Its Localization in Spermatogonia Nucleus Biomolecules doi: 10.3390/biom10050677 Authors: Massimo Venditti Alessandra Santillo Sara Falvo Maria Maddalena Di Fiore Gabriella Chieffi Baccari Sergio Minucci Cell differentiation during spermatogenesis requires a proper actin dynamic, regulated by several proteins, including formins. Disheveled-Associated-Activator of...
Tue Apr 28, 2020 03:00
Biomolecules, Vol. 10, Pages 676: Connexin-46 Contained in Extracellular Vesicles Enhance Malignancy Features in Breast Cancer Cells Biomolecules doi: 10.3390/biom10050676 Authors: Rodrigo A. Acuña Manuel Varas-Godoy Viviana M. Berthoud Ivan E. Alfaro Mauricio A. Retamal Under normal conditions, almost all cell types communicate with their neighboring cells through gap junction channels (GJC), facilitating cellular and tissue homeostasis. A GJC is formed by the interaction...
Tue Apr 28, 2020 03:00
Biosensors, Vol. 10, Pages 45: Immobilization Techniques for Aptamers on Gold Electrodes for the Electrochemical Detection of Proteins: A Review Biosensors doi: 10.3390/bios10050045 Authors: Franziska V. Oberhaus Dieter Frense Dieter Beckmann The development of reliable biosensing platforms plays a key role in the detection of proteins in clinically and environmentally derived samples for diagnostics, as well as for process monitoring in biotechnological productions. For this purpose,...
Tue Apr 28, 2020 03:00
Brain Sciences, Vol. 10, Pages 258: Examining the Effects of Anabolic–Androgenic Steroids on Repetitive Mild Traumatic Brain Injury (RmTBI) Outcomes in Adolescent Rats Brain Sciences doi: 10.3390/brainsci10050258 Authors: Jason Tabor David. K. Wright Jennaya Christensen Akram Zamani Reid Collins Sandy R. Shultz Richelle Mychasiuk Background: Repetitive mild traumatic brain injury (RmTBI) is increasingly common in adolescents. Anabolic–androgenic steroid (AAS)...
Tue Apr 28, 2020 03:00
Brain Sciences, Vol. 10, Pages 256: Therapy of Dysphagia by Prolonged Pharyngeal Electrical Stimulation (Phagenyx) in a Patient with Brainstem Infarction Brain Sciences doi: 10.3390/brainsci10050256 Authors: Cristina Florea Christine Bräumann Christine Mussger Stefan Leis Larissa Hauer Johann Sellner Stefan M. Golaszewski Dysphagia after stroke impacts quality of life and is a risk factor for respiratory infections. Patients frequently require prophylactic measures...
Tue Apr 28, 2020 03:00
Brain Sciences, Vol. 10, Pages 257: Theory of Mind Performance Predicts tDCS-Mediated Effects on the Medial Prefrontal Cortex: A Pilot Study to Investigate the Role of Sex and Age Brain Sciences doi: 10.3390/brainsci10050257 Authors: Maria Cotelli Rosa Manenti Elena Gobbi Ivan Enrici Danila Rusich Clarissa Ferrari Mauro Adenzato Transcranial Direct Current Stimulation (tDCS) has become an increasingly promising tool for understanding the relationship between brain and...
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1103: The Role of Deubiquitinating Enzymes in Hematopoiesis and Hematological Malignancies Cancers doi: 10.3390/cancers12051103 Authors: Neha Sarodaya Janardhan Karapurkar Kye-Seong Kim Seok-Ho Hong Suresh Ramakrishna Hematopoietic stem cells (HSCs) are responsible for the production of blood cells throughout the human lifespan. Single HSCs can give rise to at least eight distinct blood-cell lineages. Together, hematopoiesis, erythropoiesis, and angiogenesis...
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1102: Early Moderate Intensity Aerobic Exercise Intervention Prevents Doxorubicin-Caused Cardiac Dysfunction Through Inhibition of Cardiac Fibrosis and Inflammation Cancers doi: 10.3390/cancers12051102 Authors: Hsin-Lun Yang Pei-Ling Hsieh Ching-Hsia Hung Hui-Ching Cheng Wan-Ching Chou Pei-Ming Chu Yun-Ching Chang Kun-Ling Tsai Doxorubicin (DOX) is known as an effective drug in the fight against various cancers. However, one of the greatest...
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1101: Are Pathogenic Germline Variants in Metastatic Melanoma Associated with Resistance to Combined Immunotherapy? Cancers doi: 10.3390/cancers12051101 Authors: Teresa Amaral Martin Schulze Tobias Sinnberg Maike Nieser Peter Martus Florian Battke Claus Garbe Saskia Biskup Andrea Forschner Background: Combined immunotherapy has significantly improved survival of patients with advanced melanoma, but there are still patients that do not benefit...
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1100: Recent Developments of Systemic Chemotherapy for Gastric Cancer Cancers doi: 10.3390/cancers12051100 Authors: Hiroyuki Arai Takako Eguchi Nakajima Gastric cancer (GC) is a molecularly heterogeneous disease. Its molecular background, epidemiology, and standard of care are quite different between Eastern and Western countries. Many efforts have been made in developing more effective surgeries and adjuvant chemotherapies for resectable GC in each region....
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1104: Genetic and Immune Changes Associated with Disease Progression under the Pressure of Oncolytic Therapy in A Neuroblastoma Outlier Patient Cancers doi: 10.3390/cancers12051104 Authors: Lidia Franco-Luzón Sandra García-Mulero Rebeca Sanz-Pamplona Gustavo Melen David Ruano Álvaro Lassaletta Luís Madero África González-Murillo Manuel Ramírez Little is known about the effect of oncolytic adenovirotherapy on pediatric tumors. Here we present...
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1095: ATR Inhibition Potentiates PARP Inhibitor Cytotoxicity in High Risk Neuroblastoma Cell Lines by Multiple Mechanisms Cancers doi: 10.3390/cancers12051095 Authors: Harriet E. D. Southgate Lindi Chen Deborah A. Tweddle Nicola J. Curtin Background: High risk neuroblastoma (HR-NB) is one the most difficult childhood cancers to cure. These tumours frequently present with DNA damage response (DDR) defects including loss or mutation of key DDR genes, oncogene-induced...
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1098: Advances in Histone Demethylase KDM3A as a Cancer Therapeutic Target Cancers doi: 10.3390/cancers12051098 Authors: Jung Yoo Yu Hyun Jeon Ha Young Cho Sang Wu Lee Go Woon Kim Dong Hoon Lee So Hee Kwon Lysine-specific histone demethylase 3 (KDM3) subfamily proteins are H3K9me2/me1 histone demethylases that promote gene expression. The KDM3 subfamily primarily consists of four proteins (KDM3A−D). All four proteins contain the catalytic...
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1099: The Role of miRNA for the Treatment of MGMT Unmethylated Glioblastoma Multiforme Cancers doi: 10.3390/cancers12051099 Authors: Anna Kirstein Thomas E. Schmid Stephanie E. Combs Glioblastoma multiforme (GBM) is the most common high-grade intracranial tumor in adults. It is characterized by uncontrolled proliferation, diffuse infiltration due to high invasive and migratory capacities, as well as intense resistance to chemo- and radiotherapy. With a five-year...
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1096: Suicide Gene Therapy Mediated with Exosomes Produced by Mesenchymal Stem/Stromal Cells Stably Transduced with HSV Thymidine Kinase Cancers doi: 10.3390/cancers12051096 Authors: Andrea Pastorakova Jana Jakubechova Ursula Altanerova Cestmir Altaner Mesenchymal stem/stromal cells (MSCs) prepared from various human tissues were stably transduced with the suicide gene herpes simplex virus thymidine kinase (HSVTK) by means of retrovirus infection. HSVTK-transduced...
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1093: Mycoplasma Co-Infection Is Associated with Cervical Cancer Risk Cancers doi: 10.3390/cancers12051093 Authors: Cameron Klein Kandali Samwel Crispin Kahesa Julius Mwaiselage John T. West Charles Wood Peter C. Angeletti Tanzania faces one of the highest cervical cancer burdens in the world. Recent work has suggested that the bacterial family Mycoplasmataceae is associated with higher levels of human papillomavirus (HPV), human immunodeficiency...
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1092: MicroRNA Regulation of the Small Rho GTPase Regulators—Complexities and Opportunities in Targeting Cancer Metastasis Cancers doi: 10.3390/cancers12051092 Authors: Humphries Wang Yang The small Rho GTPases regulate important cellular processes that affect cancer metastasis, such as cell survival and proliferation, actin dynamics, adhesion, migration, invasion and transcriptional activation. The Rho GTPases function as molecular switches cycling between...
Tue Apr 28, 2020 03:00
Cancers, Vol. 12, Pages 1094: Effects of Beta-Blockers on Melanoma Microenvironment and Disease Survival in Human Cancers doi: 10.3390/cancers12051094 Authors: Ludovic Jean Wrobel Angèle Gayet-Ageron Frédérique-Anne Le Gal Background: The regulation of melanoma by noradrenergic signaling has gain attention since pre-clinical and clinical studies suggested a benefit of using beta-blockers to control disease progression. We need to confirm that human melanoma recapitulates the mechanisms...
Tue Apr 28, 2020 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου