Abstract Background This study aims to understand how sociodemographic factors influence perceptions of “Brazilian Butt Lift” (BBL), the cosmetic procedure with the highest reported mortality rate, among adult women. We also investigate whether education about risks changes willingness to receive this procedure. Methods A Qualtrics© survey including education...
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Abstract Background Although keloids and hypertrophic scars are common benign hyperproliferative growths of dermal fibroblasts, the clinical problems including physical and psychological problems are significant and impairing, with few proven treatments. Intralesional triamcinolone acetonide (TAC) and combination of TAC with 5-fluorouracil (5-FU) are widely used to treat keloids and hypertrophic scars, but their efficacy and safety remain...
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Abstract Background Abdominoplasty is a frequent aesthetic surgical procedure. Despite its popularity, patient safety requires further attention because of an important risk of complications. Obesity and bariatric surgery are potential risk factors. This study evaluated the impact of body mass index (BMI) and bariatric surgery on complications profile. Methods ...
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Level of Evidence V This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
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Publication date: Available online 27 April 2020Source: Health PolicyAuthor(s): Hiroshi Nakamura, Naohiko Wakutsu
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Publication date: Available online 26 April 2020Source: Health PolicyAuthor(s): Akihiko Ozaki, Hiroaki Saito, Yuki Senoo, Toyoaki Sawano, Yuki Shimada, Yurie Kobashi, Kana Yamamoto, Yosuke Suzuki, Tetsuya Tanimoto
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Publication date: Available online 28 April 2020Source: Experimental Cell ResearchAuthor(s): Muhammad Ibrahim, Bing Xie, Michael K. Richardson
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Publication date: Available online 28 April 2020Source: Experimental Cell ResearchAuthor(s): Jifei Miao, Sen Ye, Jiao Lan, Peng Ye, Quan Wen, Liyan Mei, Xia Liu, Junli Lin, Xiaojing Zhou, Shaohui Du, Xiaoyi Liu, Hui Li
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Publication date: Available online 25 April 2020Source: Experimental Cell ResearchAuthor(s): Kelly E. Miller, Christopher Brownlee, Rebecca Heald
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Publication date: Available online 27 April 2020Source: GeneAuthor(s): Tiam M. Saffari, Amr Badreldin, Femke Mathot, Leila Bagheri, Allen T. Bishop, Andre J. van Wijnen, Alexander Y. Shin
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Publication date: Available online 25 April 2020Source: GeneAuthor(s): Zongli Zhang, Haiqing Wu, Longjun Dai, Yue Yuan, Yanshan Zhu, Zhipeng Ma, Xuzhi Ruan, Xingrong Guo
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Publication date: Available online 28 April 2020Source: BiochimieAuthor(s): Damjan Mitić, Marin Radovčić, Dora Markulin, Ivana Ivančić-Baće
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Publication date: Available online 27 April 2020Source: BiochimieAuthor(s): Vladislav M. Shatov, Nikolai B. Gusev
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Abstract Functional neuroimaging studies using auditory stimuli consistently show activation of the insular cortex. However, due to the limited temporal resolution of non-invasive neuroimaging techniques, the role(s) of the insula in auditory processing remains unclear. As the anterior insula (aI) and the posterior insula (pI) have different connections and are thought to be functionally distinct, it is likely that these two areas contribute differently to auditory processing....
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Abstract Personality factors have been associated with Alzheimer’s disease (AD) and dementia, but they have not been examined against markers of regional brain glucose metabolism (a primary measure of brain functioning) in older adults without clinically diagnosed cognitive impairment. The relationship between personality factors derived from the five-factor model and cerebral glucose metabolism determined using positron emission tomography (PET) with [18F]-2-fluoro-2-deoxy-d-glucose...
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Abstract Faces are processed in a network of areas within regions of the ventral visual stream. However, familiar faces typically are characterized by additional associated information, such as episodic memories or semantic biographical information as well. The acquisition of such non-sensory, identity-specific knowledge plays a crucial role in our ability to recognize and identify someone we know. The occipital face area (OFA), an early part of the core face-processing network,...
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Abstract Objectives To compare the diagnostic value of the SARC-F, MRSA-7 and MRSA-5 questionnaires in screening for sarcopenia in inpatients with chronic heart failure (CHF). Patients A total of 355 CHF patients hospitalized from January 2019 to August 2019 who met the study’s selection criteria were included in the analysis. ...
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Publication date: Available online 28 April 2020Source: Cellular SignallingAuthor(s): Guo-Hua Fan, Tie-Yuan Zhu, Jie Huang
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Publication date: Available online 28 April 2020Source: Cellular SignallingAuthor(s): Yajuan Luo, Dandan Wang, Silei Chen, Qing Yang
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Publication date: July 2020Source: Biochimica et Biophysica Acta (BBA) - General Subjects, Volume 1864, Issue 7Author(s):
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Cancers, Vol. 12, Pages 1103: The Role of Deubiquitinating Enzymes in Hematopoiesis and Hematological Malignancies Cancers doi: 10.3390/cancers12051103 Authors: Neha Sarodaya Janardhan Karapurkar Kye-Seong Kim Seok-Ho Hong Suresh Ramakrishna Hematopoietic stem cells (HSCs) are responsible for the production of blood cells throughout the human lifespan. Single HSCs can give rise to at least eight distinct blood-cell lineages. Together, hematopoiesis, erythropoiesis,...
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Cancers, Vol. 12, Pages 1104: Genetic and Immune Changes Associated with Disease Progression under the Pressure of Oncolytic Therapy in A Neuroblastoma Outlier Patient Cancers doi: 10.3390/cancers12051104 Authors: Lidia Franco-Luzón Sandra García-Mulero Rebeca Sanz-Pamplona Gustavo Melen David Ruano Álvaro Lassaletta Luís Madero África González-Murillo Manuel Ramírez Little is known about the effect of oncolytic adenovirotherapy on pediatric tumors....
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Cancers, Vol. 12, Pages 1101: Are Pathogenic Germline Variants in Metastatic Melanoma Associated with Resistance to Combined Immunotherapy? Cancers doi: 10.3390/cancers12051101 Authors: Teresa Amaral Martin Schulze Tobias Sinnberg Maike Nieser Peter Martus Florian Battke Claus Garbe Saskia Biskup Andrea Forschner Background: Combined immunotherapy has significantly improved survival of patients with advanced melanoma, but there are still patients...
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Cancers, Vol. 12, Pages 1100: Recent Developments of Systemic Chemotherapy for Gastric Cancer Cancers doi: 10.3390/cancers12051100 Authors: Hiroyuki Arai Takako Eguchi Nakajima Gastric cancer (GC) is a molecularly heterogeneous disease. Its molecular background, epidemiology, and standard of care are quite different between Eastern and Western countries. Many efforts have been made in developing more effective surgeries and adjuvant chemotherapies for resectable GC in each region....
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Cancers, Vol. 12, Pages 1102: Early Moderate Intensity Aerobic Exercise Intervention Prevents Doxorubicin-Caused Cardiac Dysfunction Through Inhibition of Cardiac Fibrosis and Inflammation Cancers doi: 10.3390/cancers12051102 Authors: Hsin-Lun Yang Pei-Ling Hsieh Ching-Hsia Hung Hui-Ching Cheng Wan-Ching Chou Pei-Ming Chu Yun-Ching Chang Kun-Ling Tsai Doxorubicin (DOX) is known as an effective drug in the fight against various cancers. However, one of...
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Cancers, Vol. 12, Pages 1095: ATR Inhibition Potentiates PARP Inhibitor Cytotoxicity in High Risk Neuroblastoma Cell Lines by Multiple Mechanisms Cancers doi: 10.3390/cancers12051095 Authors: Harriet E. D. Southgate Lindi Chen Deborah A. Tweddle Nicola J. Curtin Background: High risk neuroblastoma (HR-NB) is one the most difficult childhood cancers to cure. These tumours frequently present with DNA damage response (DDR) defects including loss or mutation of key DDR genes,...
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Cancers, Vol. 12, Pages 1098: Advances in Histone Demethylase KDM3A as a Cancer Therapeutic Target Cancers doi: 10.3390/cancers12051098 Authors: Jung Yoo Yu Hyun Jeon Ha Young Cho Sang Wu Lee Go Woon Kim Dong Hoon Lee So Hee Kwon Lysine-specific histone demethylase 3 (KDM3) subfamily proteins are H3K9me2/me1 histone demethylases that promote gene expression. The KDM3 subfamily primarily consists of four proteins (KDM3A−D). All four proteins contain...
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Cancers, Vol. 12, Pages 1099: The Role of miRNA for the Treatment of MGMT Unmethylated Glioblastoma Multiforme Cancers doi: 10.3390/cancers12051099 Authors: Anna Kirstein Thomas E. Schmid Stephanie E. Combs Glioblastoma multiforme (GBM) is the most common high-grade intracranial tumor in adults. It is characterized by uncontrolled proliferation, diffuse infiltration due to high invasive and migratory capacities, as well as intense resistance to chemo- and radiotherapy. With...
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Cancers, Vol. 12, Pages 1096: Suicide Gene Therapy Mediated with Exosomes Produced by Mesenchymal Stem/Stromal Cells Stably Transduced with HSV Thymidine Kinase Cancers doi: 10.3390/cancers12051096 Authors: Andrea Pastorakova Jana Jakubechova Ursula Altanerova Cestmir Altaner Mesenchymal stem/stromal cells (MSCs) prepared from various human tissues were stably transduced with the suicide gene herpes simplex virus thymidine kinase (HSVTK) by means of retrovirus infection....
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Cancers, Vol. 12, Pages 1093: Mycoplasma Co-Infection Is Associated with Cervical Cancer Risk Cancers doi: 10.3390/cancers12051093 Authors: Cameron Klein Kandali Samwel Crispin Kahesa Julius Mwaiselage John T. West Charles Wood Peter C. Angeletti Tanzania faces one of the highest cervical cancer burdens in the world. Recent work has suggested that the bacterial family Mycoplasmataceae is associated with higher levels of human papillomavirus (HPV), human immunodeficiency...
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Cancers, Vol. 12, Pages 1094: Effects of Beta-Blockers on Melanoma Microenvironment and Disease Survival in Human Cancers doi: 10.3390/cancers12051094 Authors: Ludovic Jean Wrobel Angèle Gayet-Ageron Frédérique-Anne Le Gal Background: The regulation of melanoma by noradrenergic signaling has gain attention since pre-clinical and clinical studies suggested a benefit of using beta-blockers to control disease progression. We need to confirm that human melanoma recapitulates...
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Cancers, Vol. 12, Pages 1092: MicroRNA Regulation of the Small Rho GTPase Regulators—Complexities and Opportunities in Targeting Cancer Metastasis Cancers doi: 10.3390/cancers12051092 Authors: Humphries Wang Yang The small Rho GTPases regulate important cellular processes that affect cancer metastasis, such as cell survival and proliferation, actin dynamics, adhesion, migration, invasion and transcriptional activation. The Rho GTPases function as molecular switches cycling...
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Cancers, Vol. 12, Pages 1091: The Circular RNA Landscape of Non-Small Cell Lung Cancer Cells Cancers doi: 10.3390/cancers12051091 Authors: Nele Van Der Steen Yanhong Lyu Anne K. Hitzler Andrea C. Becker Jeanette Seiler Sven Diederichs The class of circular RNA (circRNA) is characterized by head-to-tail bonds between exons formed by backsplicing. Here, we provide a resource of circRNA expression in a comprehensive panel of 60 lung cancer and non-transformed cell...
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Cancers, Vol. 12, Pages 1090: Integrative Transcriptome Analyses of the Human Fallopian Tube: Fimbria and Ampulla—Site of Origin of Serous Carcinoma of the Ovary Cancers doi: 10.3390/cancers12051090 Authors: Ramlogan Sowamber Omar Nelson Leah Dodds Victoria DeCastro Iru Paudel Anca Milea Michael Considine Leslie Cope Andre Pinto Matthew Schlumbrecht Brian Slomovitz Patricia A. Shaw Sophia H. L. George Epithelial ovarian cancer represents...
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Cancers, Vol. 12, Pages 1088: Mevalonate Pathway Enzyme HMGCS1 Contributes to Gastric Cancer Progression Cancers doi: 10.3390/cancers12051088 Authors: I-Han Wang Tzu-Ting Huang Ji-Lin Chen Li-Wei Chu Yueh-Hsin Ping Kai-Wen Hsu Kuo-Hung Huang Wen-Liang Fang Hsin-Chen Lee Chian-Feng Chen Chen-Chung Liao Rong-Hong Hsieh Tien-Shun Yeh The 3-hydroxy-3-methylglutaryl-CoA synthase 1 (HMGCS1) is a potential regulatory node in the mevalonate...
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Cancers, Vol. 12, Pages 1089: Scientific Rationale for Combined Immunotherapy with PD-1/PD-L1 Antibodies and VEGF Inhibitors in Advanced Hepatocellular Carcinoma Cancers doi: 10.3390/cancers12051089 Authors: Masatoshi Kudo A successful phase III trial for the combination of atezolizumab and bevacizumab (the IMbrave150 trial) in advanced hepatocellular carcinoma has recently been reported. This is groundbreaking because nivolumab and pembrolizumab, both programmed cell death-1 (PD-1)...
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