Related ArticlesMajor head and neck reconstruction during the COVID-19 pandemic: The University of Pittsburgh approach. Head Neck. 2020 Apr 27;: Authors: Ranasinghe V, Mady LJ, Kim S, Ferris RL, Duvvuri U, Johnson JT, Solari MG, Sridharan S, Kubik M Abstract The 2019 novel coronavirus (COVID-19) pandemic has created significant challenges to the delivery of care for patients with advanced head and neck cancer requiring multimodality therapy. Performing...
Tue Apr 28, 2020 14:20
Related ArticlesThe Effect of Pre-operative Obstructive Sleep Apnea (OSA) Severity on the Change of Sleep Patterns in Children Undergoing Adenotonsillectomy. Indian J Pediatr. 2020 Apr 27;: Authors: Tutar B, Ekincioğlu ME, Berkiten G, Yılmazbaş P, Karaketir S, Arkan ME, Saltürk Z, Göker AE, Uyar Y PMID: 32338348 [PubMed - as supplied by publisher]
Tue Apr 28, 2020 14:20
Related ArticlesThe After Diagnosis Head and Neck cancer-specific Patient Concerns Inventory (HaNC-AD) as a pre-treatment preparation aid during the COVID-19 pandemic. Eur Arch Otorhinolaryngol. 2020 Apr 27;: Authors: Kanatas A, Rogers SN Abstract The coronavirus disease 2019 pandemic has resulted in new challenges for clinicians, head and neck cancer (HNC) patients and carers. There is evidence that the current crisis is affecting the management...
Tue Apr 28, 2020 14:20
Related ArticlesINI-1 (SMARCB1) deficient undifferentiated sinonasal carcinoma: novel paradigm of molecular testing in the diagnosis and management of sinonasal malignancies. Oncologist. 2020 Apr 26;: Authors: Shaverdashvili K, Azimi-Neko E, Cohen P, Akbar N, Ow TJ, Halmos B, Castellucci E Abstract Sinonasal tumors consist of a group of rare heterogeneous malignancies, accounting for 3-5% of all head and neck cancers. While squamous cell carcinomas...
Tue Apr 28, 2020 13:20
Related ArticlesIntraoperative use of optical coherence tomography to differentiate normal and diseased thyroid and parathyroid tissues from lymph node and fat. Lasers Med Sci. 2020 Apr 27;: Authors: Rubinstein M, Hu AC, Chung PS, Kim JH, Osann KE, Schalch P, Armstrong WB, Wong BJF Abstract The purpose of this study is twofold: (1) to determine the feasibility of optical coherence tomography (OCT) to differentiate normal and diseased tissue of the...
Tue Apr 28, 2020 13:20
Related ArticlesA rare genomic duplication in 2p14 underlies autosomal dominant hearing loss DFNA58. Hum Mol Genet. 2020 Apr 27;: Authors: Lezirovitz K, Vieira-Silva GA, Batissoco AC, Levy D, Kitajima JP, Trouillet A, Ouyang E, Zebajardi N, Sampaio-Silva J, Pedroso-Campos V, Nascimento LR, Sonoda CY, Borges VM, Vasconcelos LG, Beck RMO, Grasel SS, Jagger DJ, Grillet N, Bento RF, Mingroni-Netto RC, Oiticica J Abstract Here we define a ~ 200Kb genomic...
Tue Apr 28, 2020 13:20
Related ArticlesClinical Development of Molecular Targeted Therapy in Head and Neck Squamous Cell Carcinoma. JNCI Cancer Spectr. 2019 Dec;3(4):pkz055 Authors: Gougis P, Moreau Bachelard C, Kamal M, Gan HK, Borcoman E, Torossian N, Bièche I, Le Tourneau C Abstract A better understanding of cancer biology has led to the development of molecular targeted therapy, which has dramatically improved the outcome of some cancer patients, especially when a...
Tue Apr 28, 2020 13:20
Related ArticlesPhysical rehabilitation in patients with head and neck cancer: Impact on health-related quality of life and suitability of a post-treatment program. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):330-338 Authors: Sandmæl JA, Bye A, Solheim TS, Balstad TR, Thorsen L, Skovlund E, Kaasa S, Lund JÅ, Oldervoll L Abstract Objective: Physical rehabilitation programs hold the potential to mitigate deterioration in health-related quality...
Tue Apr 28, 2020 13:20
Related ArticlesChanges in breath cycle sensing affect outcomes in upper airway stimulation in sleep apnea. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):326-329 Authors: Steffen A, Sommer JU, Strohl K, Hasselbacher K, Suurna MV, Hofauer B, Heiser C Abstract Background: Upper Airway Stimulation (UAS) is a well-established therapy option for obstructive sleep apnea (OSA). Aims: There are no data on whether respiratory sensing contributes...
Tue Apr 28, 2020 13:20
Related ArticlesThe expanded endonasal approach in pediatric skull base surgery: A review. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):313-325 Authors: London NR, Rangel GG, Walz PC Abstract Objective: Surgery of the pediatric skull base has multiple unique challenges and has seen recent rapid advances. The objective of this review is to assess key issues in pediatric skull base surgery (SBS), including anatomic limitations, surgical approaches,...
Tue Apr 28, 2020 13:20
Related ArticlesPrediction of vestibular schwannoma recurrence using artificial neural network. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):278-285 Authors: Abouzari M, Goshtasbi K, Sarna B, Khosravi P, Reutershan T, Mostaghni N, Lin HW, Djalilian HR Abstract Objectives: To compare two statistical models, namely logistic regression and artificial neural network (ANN), in prediction of vestibular schwannoma (VS) recurrence. Methods:...
Tue Apr 28, 2020 13:20
Related ArticlesHistopathological changes to the peripheral vestibular system following meningitic labyrinthitis. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):256-266 Authors: Pauna HF, Knoll RM, Lubner RJ, Brodsky JR, Cushing SL, Hyppolito MA, Nadol JB, Remenschneider AK, Kozin ED Abstract Objective: While cochlear ossification is a common sequalae of meningitic labyrinthitis, less is known about the effects of meningitis on peripheral vestibular...
Tue Apr 28, 2020 13:20
Related ArticlesmTOR inhibitor use in head and neck squamous cell carcinoma: A meta-analysis on survival, tumor response, and toxicity. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):243-255 Authors: Patel J, Nguyen SA, Ogretmen B, Gutkind JS, Nathan CA, Day T Abstract Background: Head and neck squamous cell carcinoma (HNSCC) has been rising in incidence primarily related to HPV-associated oropharyngeal cancers. Novel molecular therapeutics are...
Tue Apr 28, 2020 13:20
Related ArticlesThe promise of immunotherapy in the treatment of young adults with oral tongue cancer. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):235-242 Authors: Nasser H, St John MA Abstract Historically considered a disease of the older male resulting from cumulative tobacco and alcohol use, more recently we have witnessed a rise in the global incidence of oral tongue squamous cell carcinoma in younger adults, particularly those without...
Tue Apr 28, 2020 13:20
Related ArticlesChildhood tonsillectomy alters the primary distribution of HPV-related oropharyngeal squamous cell carcinoma. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):210-216 Authors: Altenhofen B, DeWees TA, Ahn JW, Yeat NC, Goddu S, Chen I, Lewis JS, Thorstad WL, Chole RA, Gay HA Abstract Objectives: We investigated how tonsillectomy during childhood may influence the distribution of human papillomavirus (HPV) positive cancer of the tonsils...
Tue Apr 28, 2020 13:20
Related ArticlesHistopathology of maxillary sinus mucosa with odontogenic maxillary sinusitis. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):205-209 Authors: Sato K, Chitose SI, Sato K, Sato F, Ono T, Umeno H Abstract Objective: Histopathology of the maxillary sinus mucosa with intractable odontogenic maxillary sinusitis (OMS) was investigated and the role endoscopic sinus surgery (ESS) plays in its pathophysiology was clarified. Study...
Tue Apr 28, 2020 13:20
Related ArticlesEarly experience with feasibility of balloon sinus dilation in complicated pediatric acute frontal rhinosinusitis. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):194-199 Authors: Maurrasse SK, Hwa TP, Waldman E, Kacker A, Pearlman AN Abstract Background/Objective: Complicated acute rhinosinusitis in the pediatric population is an uncommon problem that may affect the orbit or brain and is life-threatening. This condition requires...
Tue Apr 28, 2020 13:20
Related ArticlesThe use of platelet-rich plasma in treatment of olfactory dysfunction: A pilot study. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):187-193 Authors: Yan CH, Mundy DC, Patel ZM Abstract Background: Olfactory dysfunction is a prevalent problem with a significant impact on quality of life and increased mortality. Limited effective therapies exist. Platelet-rich plasma (PRP) is an autologous biologic product with anti-inflammatory...
Tue Apr 28, 2020 13:20
Related ArticlesNeuraxial dysraphism in EPAS1-associated syndrome due to improper mesenchymal transition. Neurol Genet. 2020 Jun;6(3):e414 Authors: Rosenblum JS, Cappadona AJ, Argersinger DP, Pang Y, Wang H, Nazari MA, Munasinghe JP, Donahue DR, Jha A, Smirniotopoulos JG, Miettinen MM, Knutsen RH, Kozel BA, Zhuang Z, Pacak K, Heiss JD Abstract Objective: To investigate the effect of somatic, postzygotic, gain-of-function mutation of Endothelial Per-Arnt-Sim...
Tue Apr 28, 2020 13:20
Related ArticlesThe LncRNA H19 rs217727 Polymorphism Is Associated with Oral Squamous Cell Carcinoma Susceptibility in Iranian Population. Biomed Res Int. 2020;2020:1634252 Authors: Ghapanchi J, Ranjbar Z, Mokhtari MJ, Koohpeima F, Derakhshan M, Khademi B, Ghaderi H, Sheikhbahaei S, Aliabadi E Abstract Lack of protein-coding capacity is a main characteristic of long noncoding RNAs (lncRNAs) which, as molecular biomarkers, have found a novel pharmacological...
Tue Apr 28, 2020 13:20
Related ArticlesDental Materials Effect in Neutron Contamination: Electron Mode of a Linac. J Biomed Phys Eng. 2020 Apr;10(2):155-160 Authors: M G, M EB Abstract Background: Neutron contamination is produced in electron beams of linac when tooth or dental materials are located in the path of beam. Objective: This study aims to determine the neutron dose contamination from different dental restoration materials in electron mode of a linac....
Tue Apr 28, 2020 13:20
Related ArticlesEffect of Montelukast on the Symptom Severity Score of Allergic Rhinitis. Cureus. 2020 Mar 25;12(3):e7403 Authors: Rajput MSA, Arain AA, Rajput AA, Adeel M, Ghaffar S, Suahil A Abstract Introduction Rhinitis is a common respiratory disorder that can be broadly defined as an inflammation of nasal mucosa. Allergic rhinitis is the most common form of chronic rhinitis characterized by one or more symptoms including sneezing, nasal itching,...
Tue Apr 28, 2020 13:20
Related ArticlesDual EGFR blockade with cetuximab and erlotinib combined with anti-VEGF antibody bevacizumab in advanced solid tumors: a phase 1 dose escalation triplet combination trial. Exp Hematol Oncol. 2020;9:7 Authors: Subbiah V, Dumbrava EI, Jiang Y, Thein KZ, Naing A, Hong DS, Fu S, Piha-Paul SA, Tsimberidou AM, Janku F, Meric-Bernstam F, Kurzrock R, Falchook G Abstract Background: Angiogenesis and activation of the epidermal growth factor...
Tue Apr 28, 2020 13:20
Related ArticlesKnockdown of lncRNA NEAT1 suppresses hypoxia-induced migration, invasion and glycolysis in anaplastic thyroid carcinoma cells through regulation of miR-206 and miR-599. Cancer Cell Int. 2020;20:132 Authors: Tan X, Wang P, Lou J, Zhao J Abstract Background: Anaplastic thyroid carcinoma (ATC) is one of the most aggressive and lethal malignancies. Long non-coding RNAs (lncRNAs) are being found to play crucial roles in ATC progression....
Tue Apr 28, 2020 13:20
Related ArticlesExtrapulmonary small cell carcinoma: Prognostic factors, patterns of care, and overall survival. Eur J Surg Oncol. 2020 Apr 19;: Authors: Mandish SF, Gaskins JT, Yusuf MB, Little BP, Dunlap NE Abstract BACKGROUND: Extrapulmonary small cell carcinoma is a rare malignancy with scarce data. Treatment paradigms extrapolate from pulmonary small cell carcinoma and single institution studies. We analyzed the epidemiology, patterns of care,...
Tue Apr 28, 2020 13:20
Related ArticlesComparison Between Early Glottic Carcinoma and Epithelial Dysplastic Lesions of the Vocal Fold Via Voice Analysis. J Voice. 2020 Apr 24;: Authors: Kang YA, Chang JW, Won HR, Koo BS Abstract OBJECTIVE: Vocal fold leukoplakia is clinically defined by the presence of white mucosal lesions. Benign and malignant lesions of vocal fold leukoplakia can be distinguished clinically based on pathological biopsy. This study compared the acoustic...
Tue Apr 28, 2020 13:20
Related ArticlesWhy and When to Treat Snoring. Otolaryngol Clin North Am. 2020 Apr 23;: Authors: Yaremchuk K Abstract It is estimated that half of the adult population older than 60 years snores. This article discusses the many aspects of snoring, including impacts on bed partners, the individual who snores, and when and how to appropriately evaluate, diagnose, and treat the perpetrator. The goal is for clinicians to expand their knowledge regarding...
Tue Apr 28, 2020 13:20
Related ArticlesCompetitiveness of Otolaryngology Residency Applicants without a Home Program. Ann Otol Rhinol Laryngol. 2020 May;129(5):462-468 Authors: Wang JC, Pillutla P, Tello N, Gabrilska R, Aranke M, Bibb T, Watkins PD, Cordero J Abstract PURPOSE: Investigate if otolaryngology residency home programs (HP) are associated with advantages in National Resident Matching Program match compared to applicants without HPs. METHODS: Surveys were...
Tue Apr 28, 2020 13:20
Related ArticlesFiberoptic Endoscopic Evaluation of Swallowing in Infants and Children: Protocol, Safety, and Clinical Efficacy: 25 Years of Experience. Ann Otol Rhinol Laryngol. 2020 May;129(5):469-481 Authors: Miller CK, Willging JP Abstract BACKGROUND: The application of fiberoptic endoscopic evaluation of swallowing (FEES) in the pediatric dysphagia protocol requires specialized knowledge of pediatric conditions that result in dysphagia, recognition...
Tue Apr 28, 2020 13:20
Related ArticlesEfficacy of Multi-Modal Migraine Prophylaxis Therapy on Hyperacusis Patients. Ann Otol Rhinol Laryngol. 2020 May;129(5):421-427 Authors: Abouzari M, Tan D, Sarna B, Ghavami Y, Goshtasbi K, Parker EM, Lin HW, Djalilian HR Abstract OBJECTIVES: To evaluate the efficacy of a multi-modal migraine prophylaxis therapy for patients with hyperacusis. METHODS: In a prospective cohort, patients with hyperacusis were treated with a multi-modal...
Tue Apr 28, 2020 13:20
Related ArticlesResponse to commentary on "the middle fossa approach with self-drilling screws: a novel technique for BONEBRIDGE implantation". J Otolaryngol Head Neck Surg. 2019 11 05;48(1):57 Authors: You P, Siegel LH, Kassam Z, Hebb M, Parnes L, Ladak H, Agrawal SK Abstract The aim of this letter is to respond to a commentary on a published article on the middle fossa approach to BONEBRIDGE implantation with self-drilling screws published by the...
Tue Apr 28, 2020 13:20
Related ArticlesAddition of decellularized extracellular matrix of porcine nasal cartilage improves cartilage regenerative capacities of PCL-based scaffolds in vitro. J Mater Sci Mater Med. 2019 Oct 26;30(11):121 Authors: Wiggenhauser PS, Schwarz S, Koerber L, Hoffmann TK, Rotter N Abstract Composite scaffolds can improve regenerative capacities of scaffolds in various tissue-engineering approaches. In order to generate a 3D printable scaffold that...
Tue Apr 28, 2020 13:20
Related ArticlesIntranasal Bolsters: A Novel Technique for Nasal Bone Stabilization. J Craniofac Surg. 2020 Jan/Feb;31(1):e43-e45 Authors: Shokri T, Hilger PA, Lighthall JG Abstract Nasal bone stabilization, in the setting of comminuted nasal fracture or surgical osteotomy, represents a challenging surgical experience. Postoperative shifting of osseous fragments may result in compromised outcomes in an otherwise well-performed procedure. Although prior...
Tue Apr 28, 2020 13:20
Related ArticlesClinicopathologic analysis of verrucous hyperplasia, verrucous carcinoma and squamous cell carcinoma as part of the clinicopathologic spectrum of oral proliferative verrucous leukoplakia: A literature review and analysis. Pathol Res Pract. 2019 Dec;215(12):152670 Authors: Akrish S, Eskander-Hashoul L, Rachmiel A, Ben-Izhak O Abstract OBJECTIVE: Proliferative verrucous leukoplakia is classified as a potentially malignant disorder because...
Tue Apr 28, 2020 13:20
Related ArticlesPrimary intrafascial desmoplastic melanoma with pseudoglandular differentiation and aberrant cytokeratins expression: An exceptional presentation. Pathol Res Pract. 2019 Dec;215(12):152668 Authors: Saggini A, Cerroni L, Casini B, Baciorri F, Cota C Abstract Desmoplastic melanoma (DM) is an uncommon variant of malignant melanoma (MM), histologically characterized by a mainly dermal proliferation of spindled cells within a desmoplastic...
Tue Apr 28, 2020 13:20
Related ArticlesNasal nitric oxide in relation to psychiatric status of patients with empty nose syndrome. Nitric Oxide. 2019 11 01;92:55-59 Authors: Fu CH, Wu CL, Huang CC, Chang PH, Chen YW, Lee TJ Abstract BACKGROUND: Although cases of empty nose syndrome (ENS) are not very common, the suffering that ENS causes patient is immense and could be very difficult to imagine. Nasal nitric oxide (nNO) is an airway disease biomarker, and its levels increase...
Tue Apr 28, 2020 13:20
Related ArticlesAn Analysis of Association Between Nasal Bone Morphology and Sinonasal Anatomical Variations. J Craniofac Surg. 2020 Jan/Feb;31(1):37-40 Authors: Kuzucu I, Parlak S, Baklaci D, Guler I, Sakalli C, Mendi AB, Kum RO, Ozcan M Abstract The goal of this study was to investigate the association between various sinonasal anatomical variations and the morphological features of lateral nasal bone, using paranasal computerized tomography (PNCT)...
Tue Apr 28, 2020 13:20
Related ArticlesMathematical models for dynamic, multisensory spatial orientation perception. Prog Brain Res. 2019;248:65-90 Authors: Clark TK, Newman MC, Karmali F, Oman CM, Merfeld DM Abstract Mathematical models have been proposed for how the brain interprets sensory information to produce estimates of self-orientation and self-motion. This process, spatial orientation perception, requires dynamically integrating multiple sensory modalities, including...
Tue Apr 28, 2020 13:20
Related ArticlesModel of optokinetic responses involving two different visual motion processing pathways. Prog Brain Res. 2019;248:329-340 Authors: Miura K, Takemura A, Taki M, Kawano K Abstract To understand visual motion processing underlying the optokinetic response (OKR), we developed a biomimetic model that reproduces the findings from behavioral experiments. We recorded OKRs induced by drifting gratings with different spatiotemporal frequencies...
Tue Apr 28, 2020 13:20
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