Related ArticlesManagement of Aneurysmal Subarachnoid Hemorrhage - Variation in Clinical Practice and Unmet Need for Follow-up among Survivors - A Single Center Perspective. World Neurosurg. 2020 Apr 24;: Authors: Delpirou-Nouh C, Samkutty DG, Chandrashekhar S, Santucci JA, Ford L, Xu C, Hollabaugh KM, Bohnstedt BN, Ray B Abstract OBJECTIVE: Purpose of the present study is to investigate the existence and/or prevalence of clinical practice variation...
Tue Apr 28, 2020 14:35
Related ArticlesPituitary Blastoma in a 19-Year-Old Woman: A Case Report and Review of Literature. World Neurosurg. 2020 Apr 24;: Authors: Chhuon Y, Weon YC, Park G, Kim M, Park JB, Park SK Abstract BACKGROUND: Pituitary blastoma is a malignant neoplasm of the pituitary gland that was recognized by the World Health Organization in 2017. It is commonly diagnosed in children before 24 months of age. Here, we report the first case of a young adult patient...
Tue Apr 28, 2020 14:35
Related ArticlesEvidence for the Capability of Roxadustat (FG-4592), an Oral HIF Prolyl-Hydroxylase Inhibitor, to Perturb Membrane Ionic Currents: An Unidentified yet Important Action. Int J Mol Sci. 2019 Nov 29;20(23): Authors: Chang WT, Lo YC, Gao ZH, Wu SN Abstract Roxadustat (FG-4592), an analog of 2-oxoglutarate, is an orally-administered, heterocyclic small molecule known to be an inhibitor of hypoxia inducible factor (HIF) prolyl hydroxylase....
Tue Apr 28, 2020 14:31
145 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2020/04/28PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Apr 28, 2020 14:28
Related ArticlesDirected Assembly of Elastin-like Proteins into defined Supramolecular Structures and Cargo Encapsulation In Vitro. J Vis Exp. 2020 Apr 08;(158): Authors: Schreiber A, Stühn LG, Geissinger SE, Huber MC, Schiller SM Abstract Tailored proteinaceous building blocks are versatile candidates for the assembly of supramolecular structures such as minimal cells, drug delivery vehicles and enzyme scaffolds. Due to their biocompatibility and...
Tue Apr 28, 2020 14:26
Related ArticlesLaser Capture Microdissection of Glioma Subregions for Spatial and Molecular Characterization of Intratumoral Heterogeneity, Oncostreams, and Invasion. J Vis Exp. 2020 Apr 12;(158): Authors: Comba A, Dunn PJ, Kish PE, Kadiyala P, Kahana A, Castro MG, Lowenstein PR Abstract Gliomas are primary brain tumors characterized by their invasiveness and heterogeneity. Specific histological patterns such as pseudopalisades, microvascular proliferation,...
Tue Apr 28, 2020 14:26
Related ArticlesDetection of Protein S-Acylation using Acyl-Resin Assisted Capture. J Vis Exp. 2020 Apr 10;(158): Authors: Tewari R, West SJ, Shayahati B, Akimzhanov AM Abstract Protein S-acylation, also referred to as S-palmitoylation, is a reversible post-translational modification of cysteine residues with long-chain fatty acids via a labile thioester bond. S-acylation, which is emerging as a widespread regulatory mechanism, can modulate almost...
Tue Apr 28, 2020 14:26
Related ArticlesComputation of Atmospheric Concentrations of Molecular Clusters from ab initio Thermochemistry. J Vis Exp. 2020 Apr 08;(158): Authors: Odbadrakh TT, Gale AG, Ball BT, Temelso B, Shields GC Abstract The computational study of the formation and growth of atmospheric aerosols requires an accurate Gibbs free energy surface, which can be obtained from gas phase electronic structure and vibrational frequency calculations. These quantities...
Tue Apr 28, 2020 14:26
Related ArticlesA Finite Element Approach for Locating the Center of Resistance of Maxillary Teeth. J Vis Exp. 2020 Apr 08;(158): Authors: Luu B, Cronauer EA, Gandhi V, Kaplan J, Pierce DM, Upadhyay M Abstract The center of resistance (CRES) is regarded as the fundamental reference point for predictable tooth movement. The methods used to estimate the CRES of teeth range from traditional radiographic and physical measurements to in vitro analysis...
Tue Apr 28, 2020 14:26
Related ArticlesDrug Screening of Primary Patient Derived Tumor Xenografts in Zebrafish. J Vis Exp. 2020 Apr 10;(158): Authors: Haney MG, Moore LH, Blackburn JS Abstract Patient derived xenograft models are critical in defining how different cancers respond to drug treatment in an in vivo system. Mouse models are the standard in the field, but zebrafish have emerged as an alternative model with several advantages, including the ability for high-throughput...
Tue Apr 28, 2020 14:26
Related ArticlesPurification of Prominin-1+ Stem Cells from Postnatal Mouse Cerebellum. J Vis Exp. 2020 Apr 12;(158): Authors: Edamakanti CR, Opal P Abstract Most cerebellar neurons arise from two embryonic stem niches: a rhombic lip niche, which generates all the cerebellar excitatory glutamatergic neurons, and a ventricular zone niche, which generates the inhibitory GABAergic Purkinje cells, which are neurons that constitute the deep cerebellar...
Tue Apr 28, 2020 14:26
Related ArticlesSeparation of the Cell Envelope for Gram-negative Bacteria into Inner and Outer Membrane Fractions with Technical Adjustments for Acinetobacter baumannii. J Vis Exp. 2020 Apr 10;(158): Authors: Cian MB, Giordano NP, Mettlach JA, Minor KE, Dalebroux ZD Abstract This method works by partitioning the envelope of Gram-negative bacteria into total, inner, and outer membrane (OM) fractions and concludes with assays to assess the purity...
Tue Apr 28, 2020 14:26
Related ArticlesStudy of Short Peptide Adsorption on Solution Dispersed Inorganic Nanoparticles Using Depletion Method. J Vis Exp. 2020 Apr 11;(158): Authors: Korina E, Naifert S, Morozov R, Potemkin V, Bol'shakov O Abstract Fundamentals of inorganic-organic interactions are critically important in the discovery and development of novel biointerfaces amenable for utilization in biotechnology and medicine. Recent studies indicate that proteins interact...
Tue Apr 28, 2020 14:26
Related ArticlesA 3D Spheroid Model for Glioblastoma. J Vis Exp. 2020 Apr 09;(158): Authors: Guyon J, Andrique L, Pujol N, Røsland GV, Recher G, Bikfalvi A, Daubon T Abstract Two-dimensional (2D) cell cultures do not mimic in vivo tumor growth satisfactorily. Therefore, three-dimensional (3D) culture spheroid models were developed. These models may be particularly important in the field of neuro-oncology. Indeed, brain tumors have the tendency to...
Tue Apr 28, 2020 14:26
Related ArticlesHuman Circadian Phenotyping and Diurnal Performance Testing in the Real World. J Vis Exp. 2020 Apr 07;(158): Authors: Facer-Childs ER, Middleton B, Bagshaw AP, Skene DJ Abstract In our continuously developing 'around the clock' society, there is a need to increase our understanding of how changes in biology, physiology and psychology influence our health and performance. Embedded within this challenge, is the increasing need to account...
Tue Apr 28, 2020 14:26
Related ArticlesMay ultrasonography be considered a useful tool for bedside screening of dysphagia in patients with acute stroke? A cohort study. Minerva Med. 2020 Apr 23;: Authors: Picelli A, Modenese A, Poletto E, Businaro V, Varalta V, Gandolfi M, Bonetti B, Smania N Abstract BACKGROUND: Dysphagia is a primary risk factor for pneumonia and affects around 50% of acute stroke patients. Systematic bedside swallowing screening of acute stroke patients...
Tue Apr 28, 2020 14:26
Related ArticlesGenetic Polymorphisms as non-modifiable susceptibility factors to Laryngeal cancer. Biosci Rep. 2020 Apr 27;: Authors: Escalante P, Barría T, Cancino M, Rahal M, Cerpa L, Sandoval C, Molina S, Suárez M, Martínez M, Cáceres D, Quiñones LA, Varela NM Abstract Laryngeal squamous cell carcinoma (LSCC) is a highly disabling disease to the patient, affecting speech, swallowing and respiratory skills. Smoking and alcohol abuse are principal...
Tue Apr 28, 2020 14:26
Related ArticlesmTOR inhibitor use in head and neck squamous cell carcinoma: A meta-analysis on survival, tumor response, and toxicity. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):243-255 Authors: Patel J, Nguyen SA, Ogretmen B, Gutkind JS, Nathan CA, Day T Abstract Background: Head and neck squamous cell carcinoma (HNSCC) has been rising in incidence primarily related to HPV-associated oropharyngeal cancers. Novel molecular therapeutics are evolving...
Tue Apr 28, 2020 14:26
Related ArticlesPredictive factors for local control of early glottic squamous cell carcinomas after definitive radiotherapy. Mol Clin Oncol. 2020 Jun;12(6):541-550 Authors: Okubo M, Itonaga T, Saito T, Shiraishi S, Mikami R, Sakurada A, Sugahara S, Park J, Tokuuye K, Saito K Abstract The aim of the present study was to retrospectively investigate the risk factors of local failure for T1 glottic carcinoma irradiated with a prescription dose of 66 Gy....
Tue Apr 28, 2020 14:26
Related ArticlesThe Effects of Photobiomodulation on Vocal Fold Wound Healing: In Vivo and In Vitro Studies. Photobiomodul Photomed Laser Surg. 2019 Sep;37(9):532-538 Authors: Lou Z, Gong T, Kang J, Xue C, Ulmschneider C, Jiang JJ Abstract Background: Photobiomodulation (PBM) is increasingly used in dermatology and dentistry due to its benefit of promoting wound healing and relieving pain; however, there is no corresponding research report on the application...
Tue Apr 28, 2020 14:26
Related ArticlesEffect of a Mandibular Advancement Device on the Upper Airway in a Patient With Obstructive Sleep Apnea. J Craniofac Surg. 2020 Jan/Feb;31(1):e32-e35 Authors: Flores-Orozco EI, Tiznado-Orozco GE, Díaz-Peña R, Orozco EIF, Galletti C, Gazia F, Galletti F Abstract The authors present a case of a 33-year-old male patient with obstructive sleep apnea syndrome who was treated with a mandibular advancement device with excellent results. The...
Tue Apr 28, 2020 14:26
Related ArticlesMaking cricothyroid membrane a part of routine pre-op airway assessment. J Clin Anesth. 2019 Nov;57:74 Authors: Karmakar A, Kumar N PMID: 30889509 [PubMed - indexed for MEDLINE]
Tue Apr 28, 2020 14:26
Related ArticlesThe expanded endonasal approach in pediatric skull base surgery: A review. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):313-325 Authors: London NR, Rangel GG, Walz PC Abstract Objective: Surgery of the pediatric skull base has multiple unique challenges and has seen recent rapid advances. The objective of this review is to assess key issues in pediatric skull base surgery (SBS), including anatomic limitations, surgical approaches,...
Tue Apr 28, 2020 14:25
Related ArticlesPrediction of vestibular schwannoma recurrence using artificial neural network. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):278-285 Authors: Abouzari M, Goshtasbi K, Sarna B, Khosravi P, Reutershan T, Mostaghni N, Lin HW, Djalilian HR Abstract Objectives: To compare two statistical models, namely logistic regression and artificial neural network (ANN), in prediction of vestibular schwannoma (VS) recurrence. Methods: Seven...
Tue Apr 28, 2020 14:25
Related ArticlesOsteomyelitis following an undisplaced basal skull fracture. N Z Med J. 2020 02 07;133(1509):73-76 Authors: Seddon K, Low C PMID: 32027641 [PubMed - indexed for MEDLINE]
Tue Apr 28, 2020 14:25
Related ArticlesActive Cushing Disease Is Characterized by Increased Adipose Tissue Macrophage Presence. J Clin Endocrinol Metab. 2019 06 01;104(6):2453-2461 Authors: Lee IT, Atuahene A, Egritag HE, Wang L, Donovan M, Buettner C, Geer EB Abstract CONTEXT: Although glucocorticoids (GCs) have potent anti-inflammatory actions, patients with hypercortisolism due to Cushing disease (CD) have increased circulating proinflammatory cytokines that may contribute...
Tue Apr 28, 2020 14:25
Related ArticlesExtrapolating the Limits of the Nasoseptal Flap With Pedicle Dissection to the Internal Maxillary Artery. Oper Neurosurg (Hagerstown). 2019 01 01;16(1):37-44 Authors: Pinheiro-Neto CD, Peris-Celda M, Kenning T Abstract BACKGROUND: The nasoseptal flap is the main pedicled flap used for endoscopic cranial base reconstruction. For large anterior cranial base defects, the anterior edge is a concern for the nasoseptal flap reach. ...
Tue Apr 28, 2020 14:25
Related ArticlesLINC01128 resisted acute myeloid leukemia through regulating miR-4260/NR3C2. Cancer Biol Ther. 2020 Apr 26;:1-8 Authors: Li H, Tian X, Wang P, Hu J, Qin R, Xu R, Liu K, Hao J, Tian N Abstract Acute myeloid leukemia (AML) is a prevalent class of blood disease with a high occurrence rate and relapse rate. The role of dysregulated microRNAs (miRNAs) in AML is emerging. MiR-4260 was identified to be a carcinogenic miRNA in colorectal cancer,...
Tue Apr 28, 2020 14:24
Related ArticlesEndoscopic Septoplasty Versus Traditional Septoplasty for Treating Deviated Nasal Septum: A Prospective, Randomized Controlled Trial. Ear Nose Throat J. 2020 Apr 27;:145561320918982 Authors: Na'ara S, Kaptzan B, Gil Z, Ostrovsky D Abstract IMPORTANCE: This is the first randomized study to compare the quality of life of patients undergoing endoscopic septoplasty compared to traditional trans-nasal trans-speculum (TNTS) septoplasty. ...
Tue Apr 28, 2020 14:22
Related ArticlesPhysical rehabilitation in patients with head and neck cancer: Impact on health-related quality of life and suitability of a post-treatment program. Laryngoscope Investig Otolaryngol. 2020 Apr;5(2):330-338 Authors: Sandmæl JA, Bye A, Solheim TS, Balstad TR, Thorsen L, Skovlund E, Kaasa S, Lund JÅ, Oldervoll L Abstract Objective: Physical rehabilitation programs hold the potential to mitigate deterioration in health-related quality of...
Tue Apr 28, 2020 14:22
Related ArticlesFiberoptic Endoscopic Evaluation of Swallowing in Infants and Children: Protocol, Safety, and Clinical Efficacy: 25 Years of Experience. Ann Otol Rhinol Laryngol. 2020 May;129(5):469-481 Authors: Miller CK, Willging JP Abstract BACKGROUND: The application of fiberoptic endoscopic evaluation of swallowing (FEES) in the pediatric dysphagia protocol requires specialized knowledge of pediatric conditions that result in dysphagia, recognition...
Tue Apr 28, 2020 14:22
Related ArticlesAge-Related Changes in Temporal Resolution Revisited: Electrophysiological and Behavioral Findings From Cochlear Implant Users. Ear Hear. 2019 Nov/Dec;40(6):1328-1344 Authors: Mussoi BSS, Brown CJ Abstract OBJECTIVES: The mechanisms underlying age-related changes in speech perception are still unclear, most likely multifactorial and often can be difficult to parse out from the effects of hearing loss. Age-related changes in temporal...
Tue Apr 28, 2020 14:22
Related ArticlesEffect of Compression on Musical Sound Quality in Cochlear Implant Users. Ear Hear. 2019 Nov/Dec;40(6):1368-1375 Authors: Gilbert M, Jiradejvong P, Limb C Abstract OBJECTIVES: Cochlear implant (CI) users frequently report poor sound quality while listening to music, although the specific parameters responsible for this loss of sound quality remain poorly understood. Audio compression, which reduces the dynamic range (DR) for a given...
Tue Apr 28, 2020 14:22
Related ArticlesFluorometric detection of iodine by MIL-53(Al)-TDC. Dalton Trans. 2020 Apr 27;: Authors: Díaz-Ramírez ML, Vargas B, Raziel Álvarez J, Landeros-Rivera B, Rivera-Almazo M, Ramos C, Gabriel Flores J, Morales E, Vargas R, Garza J, González-Zamora E, Martínez A, Solís-Ibarra D, Ibarra IA Abstract The fluorescent properties of MIL-53(Al)-TDC are drastically changed due to the presence of iodine, even in small quantities, as a result of...
Tue Apr 28, 2020 14:17
Related ArticlesFournier's gangrene during lenvatinib treatment: A case report. Mol Clin Oncol. 2020 Jun;12(6):588-591 Authors: Barone M, Grani G, Ramundo V, Garritano T, Durante C, Falcone R Abstract Fournier's gangrene is a rare and severe complication reported in patients with cancer treated with antiangiogenic drugs, most frequently with bevacizumab. The present report describes the case of an 80-year-old man with radioactive iodine-refractory...
Tue Apr 28, 2020 14:17
Related ArticlesAcute Myeloid Leukemia after Low-Dose Radioiodine Therapy for Papillary Thyroid Carcinoma. Case Rep Oncol. 2020 Jan-Apr;13(1):207-211 Authors: Alsaud A, Mohamed S, Yassin MA, Ashour A, Obeidat K, Azrieh B Abstract Papillary thyroid carcinoma is the most common primary thyroid cancer. Most frequently treated with surgical resection, some cases require radioactive iodine (RAI) therapy. Studies have suggested that there is an increase...
Tue Apr 28, 2020 14:17
Nature Communications, Published online: 28 April 2020; doi:10.1038/s41467-020-15723-wFor colloidal particles, it remains challenging to predict the forms of order that can emerge in their dense assembled structures. Here, the authors show, by Monte Carlo simulations, that tetratic-ordered phases emerge in a dense two-dimensional system of hard kites that are rotationally asymmetric.
Tue Apr 28, 2020 03:00
Nature Communications, Published online: 28 April 2020; doi:10.1038/s41467-020-15937-yClassical human dendritic cells (cDCs) are rare sentinel cells specialized in regulating adaptive immunity. Here, the authors show that expression of membrane bound FLT3L, along with stem cell factor (SCF) and CXCL12 in stromal cells induces specification of pre/AS-DCs, type 1 and type2 cDC from haematopoietic stem cells.
Tue Apr 28, 2020 03:00
Nature Communications, Published online: 28 April 2020; doi:10.1038/s41467-020-15465-9Testing mechanical forces on native molecules in natural environments remains a challenge. Here the authors engineer titin to carry a HaloTag-TEV insertion to allow analysis of dynamics under force in muscle fibers.
Tue Apr 28, 2020 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου