IJMS, Vol. 21, Pages 3112: Involvement of Senescence and Mitochondrial Fission in Endothelial Cell Pro-Inflammatory Phenotype Induced by Angiotensin II International Journal of Molecular Sciences doi: 10.3390/ijms21093112 Authors: Miyao Cicalese Kawai Cooper Boyer Elliott Forrester Kuroda Rizzo Hashimoto Scalia Eguchi Angiotensin II (AngII) has a crucial role in cardiovascular pathologies, including endothelial inflammation and premature vascular...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3110: Sensor Histidine Kinase NarQ Activates via Helical Rotation, Diagonal Scissoring, and Eventually Piston-Like Shifts International Journal of Molecular Sciences doi: 10.3390/ijms21093110 Authors: Ivan Gushchin Philipp Orekhov Igor Melnikov Vitaly Polovinkin Anastasia Yuzhakova Valentin Gordeliy Membrane-embedded sensor histidine kinases (HKs) and chemoreceptors are used ubiquitously by bacteria and archaea to percept the environment, and are often...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3108: Synergistic Combinations of Curcumin, Sulforaphane, and Dihydrocaffeic Acid against Human Colon Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21093108 Authors: Jesús Santana-Gálvez Javier Villela-Castrejón Sergio O. Serna-Saldívar Luis Cisneros-Zevallos Daniel A. Jacobo-Velázquez Nutraceutical combinations that act synergistically could be a powerful solution against colon cancer, which is the second deadliest malignancy...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3111: Dry Eye Disease and Tear Cytokine Levels—A Meta-Analysis International Journal of Molecular Sciences doi: 10.3390/ijms21093111 Authors: Roda Corazza Reggiani Pellegrini Taroni Giannaccare Versura Background—It is recognized that inflammation is an underlying cause of dry eye disease (DED), with cytokine release involved. We systematically reviewed literature with meta-analyses to quantitatively summarize the levels of tear...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3109: Bone Disease in Nephropathic Cystinosis: Beyond Renal Osteodystrophy International Journal of Molecular Sciences doi: 10.3390/ijms21093109 Authors: Machuca-Gayet Quinaux Bertholet-Thomas Gaillard Claramunt-Taberner Acquaviva-Bourdain Bacchetta Patients with chronic kidney disease (CKD) display significant mineral and bone disorders (CKD-MBD) that induce significant cardiovascular, growth and bone comorbidities. Nephropathic cystinosis...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3105: Genetic Architecture of Early Vigor Traits in Wild Soybean International Journal of Molecular Sciences doi: 10.3390/ijms21093105 Authors: Kofsky Zhang Song A worldwide food shortage has been projected as a result of the current increase in global population and climate change. In order to provide sufficient food to feed more people, we must develop crops that can produce higher yields. Plant early vigor traits, early growth rate (EGR), early plant...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3104: Functional Role of Dietary Intervention to Improve the Outcome of COVID-19: A Hypothesis of Work International Journal of Molecular Sciences doi: 10.3390/ijms21093104 Authors: Giovanni Messina Rita Polito Vincenzo Monda Luigi Cipolloni Nunzio Di Nunno Giulio Di Mizio Paolo Murabito Marco Carotenuto Antonietta Messina Daniela Pisanelli Anna Valenzano Giuseppe Cibelli Alessia Scarinci Marcellino Monda Francesco Sessa Background:...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3106: Re-Setting the Circadian Clock Using Exercise against Sarcopenia International Journal of Molecular Sciences doi: 10.3390/ijms21093106 Authors: Choi Cho No Heo Cho Chang Park Kang Kwak Sarcopenia is defined as the involuntary loss of skeletal muscle mass and function with aging and is associated with several adverse health outcomes. Recently, the disruption of regular circadian rhythms, due to shift work or nocturnal lifestyle,...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3101: Integrated Analysis of mRNA and microRNA Elucidates the Regulation of Glycyrrhizic Acid Biosynthesis in Glycyrrhiza uralensis Fisch International Journal of Molecular Sciences doi: 10.3390/ijms21093101 Authors: Yanni Li Caixia Chen Zhenzhen Xie Jing Xu Bin Wu Wenquan Wang Licorice (Glycyrrhiza) is a staple Chinese herbal medicine in which the primary bioactive compound is glycyrrhizic acid (GA), which has important pharmacological functions....
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3100: Redox Homeostasis and Metabolism in Cancer: A Complex Mechanism and Potential Targeted Therapeutics International Journal of Molecular Sciences doi: 10.3390/ijms21093100 Authors: Alia Ghoneum Ammar Yasser Abdulfattah Bailey Olivia Warren Junjun Shu Neveen Said Reactive Oxygen Species or “ROS” encompass several molecules derived from oxygen that can oxidize other molecules and subsequently transition rapidly between species. The...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3099: Structural and Evolutionary Analysis Indicate That the SARS-CoV-2 Mpro Is a Challenging Target for Small-Molecule Inhibitor Design International Journal of Molecular Sciences doi: 10.3390/ijms21093099 Authors: Maria Bzówka Karolina Mitusińska Agata Raczyńska Aleksandra Samol Jack A. Tuszyński Artur Góra The novel coronavirus whose outbreak took place in December 2019 continues to spread at a rapid rate worldwide. In the absence of an effective...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3098: Degradation, Bone Regeneration and Tissue Response of an Innovative Volume Stable Magnesium-Supported GBR/GTR Barrier Membrane International Journal of Molecular Sciences doi: 10.3390/ijms21093098 Authors: Mike Barbeck Lennart Kühnel Frank Witte Jens Pissarek Clarissa Precht Xin Xiong Rumen Krastev Nils Wegner Frank Walther Ole Jung Introduction: Bioresorbable collagenous barrier membranes are used to prevent premature soft tissue...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3096: Proteomic Profiling of Colon Cancer Tissues: Discovery of New Candidate Biomarkers International Journal of Molecular Sciences doi: 10.3390/ijms21093096 Authors: Miriam Buttacavoli Nadia Ninfa Albanese Elena Roz Ida Pucci-Minafra Salvatore Feo Patrizia Cancemi Colon cancer is an aggressive tumor form with a poor prognosis. This study reports a comparative proteomic analysis performed by using two-dimensional differential in-gel electrophoresis...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3097: Low-Molecular-Weight Heparin Reduces Ventilation-Induced Lung Injury through Hypoxia Inducible Factor-1α in a Murine Endotoxemia Model International Journal of Molecular Sciences doi: 10.3390/ijms21093097 Authors: Li-Fu Li Yung-Yang Liu Shih-Wei Lin Chih-Hao Chang Ning-Hung Chen Chen-Yiu Hung Chung-Shu Lee Patients with sepsis frequently require mechanical ventilation (MV) to survive. However, MV has been shown to induce the production of...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3095: In Utero Exposure to Bisphenol a Promotes Mammary Tumor Risk in MMTV-Erbb2 Transgenic Mice Through the Induction of ER-erbB2 Crosstalk International Journal of Molecular Sciences doi: 10.3390/ijms21093095 Authors: Zhikun Ma Amanda B. Parris Erin W. Howard Meghan Davis Xia Cao Courtney Woods Xiaohe Yang Bisphenol A (BPA) is the most common environmental endocrine disrupting chemical. Studies suggest a link between perinatal BPA exposure and...
Tue Apr 28, 2020 03:00
IJMS, Vol. 21, Pages 3094: Transcriptome Analysis of Paralichthys olivaceus Erythrocytes Reveals Profound Immune Responses Induced by Edwardsiella tarda Infection International Journal of Molecular Sciences doi: 10.3390/ijms21093094 Authors: Bin Sun Xuepeng Li Xianhui Ning Li Sun Unlike mammalian red blood cells (RBCs), fish RBCs are nucleated and thus capable of gene expression. Japanese flounder (Paralichthys olivaceus) is a species of marine fish with important economic values....
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1279: Impact of Mononuclear Cell Infiltration on Chondrodestructive MMP/ADAMTS Production in Osteoarthritic Knee Joints—An Ex Vivo Study Journal of Clinical Medicine doi: 10.3390/jcm9051279 Authors: Platzer Nees Reiner Tripel Gantz Hagmann Moradi Rosshirt Progressive loss of joint function in osteoarthritis (OA) is driven by degenerative and inflammatory processes and their complex interaction. Decoding the link between degeneration and...
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1278: Sexual Dimorphism of NAFLD in Adults. Focus on Clinical Aspects and Implications for Practice and Translational Research Journal of Clinical Medicine doi: 10.3390/jcm9051278 Authors: Lonardo Suzuki Nonalcoholic fatty liver disease (NAFLD) embraces the clinico-pathological consequences of hepatic lipotoxicity and is a major public health problem globally. Sexual dimorphism is a definite feature of most human diseases but, under this aspect, NAFLD lags behind...
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1273: Revisiting Inflammatory Bowel Disease: Pathology, Treatments, Challenges and Emerging Therapeutics Including Drug Leads from Natural Products Journal of Clinical Medicine doi: 10.3390/jcm9051273 Authors: Karma Yeshi Roland Ruscher Luke Hunter Norelle L. Daly Alex Loukas Phurpa Wangchuk Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by gastrointestinal tract inflammation. It is caused by the interplay of the host’s...
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1280: Immunomodulatory Strategies Targeting Dendritic Cells to Improve Corneal Graft Survival Journal of Clinical Medicine doi: 10.3390/jcm9051280 Authors: Schönberg Hamdorf Bock Even though the cornea is regarded as an immune-privileged tissue, transplantation always comes with the risk of rejection due to mismatches between donor and recipient. It is common sense that an alternative to corticosteroids as the current gold standard for treatment of corneal...
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1276: Gene Expression Patterns Distinguish Mortality Risk in Patients with Postsurgical Shock Journal of Clinical Medicine doi: 10.3390/jcm9051276 Authors: Pedro Martínez-Paz Marta Aragón-Camino Esther Gómez-Sánchez Mario Lorenzo-López Estefanía Gómez-Pesquera Rocío López-Herrero Belén Sánchez-Quirós Olga de la Varga Álvaro Tamayo-Velasco Christian Ortega-Loubon Emilio García-Morán Hugo Gonzalo-Benito María Heredia-Rodríguez Eduardo...
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1277: Analyzing Impetus of Regenerative Cellular Therapeutics in Myocardial Infarction Journal of Clinical Medicine doi: 10.3390/jcm9051277 Authors: Chang Chiu Li Cheah Lin Both vasculature and myocardium in the heart are excessively damaged following myocardial infarction (MI), hence therapeutic strategies for treating MI hearts should concurrently aim for true cardiac repair by introducing new cardiomyocytes to replace lost or injured ones. Of them,...
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1275: Lymphatic Invasion Might Be Considered as an Upstaging Factor in N0 and N1 Gastric Cancer Journal of Clinical Medicine doi: 10.3390/jcm9051275 Authors: Won Hyuk Choi Min Jeong Kim Jun Ho Park Jin Gu Kang Seung In Seo Hak Yang Kim Woon Geon Shin (Background) The aim of this study was to investigate the prognostic impact of lymphatic invasion in gastric cancer, focusing on survival differences between N stage groups. (Methods) A total of 398 consecutive...
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1274: Novel Treatment Strategy for Management of Traumatic Bulbar Urethral Rupture Using Temporary Urethral Stent after Primary Realignment; Retrospective Comparison between Thermo-Expandable Urethral Stent and Self-Expandable Polymer-Coated Urethral Stent Journal of Clinical Medicine doi: 10.3390/jcm9051274 Authors: Ahn Lee Kim Moon A variety of retrievable and other types of temporarily placed stents are currently being used. However, only a few studies...
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1271: Prenatal Exposure to Preeclampsia and Long-Term Ophthalmic Morbidity of the Offspring Journal of Clinical Medicine doi: 10.3390/jcm9051271 Authors: Eliel Kedar Sade Tamar Wainstock Erez Tsumi Eyal Sheiner The aim of this population-based study was to evaluate whether prenatal exposure to preeclampsia poses a risk for long-term ophthalmic morbidity. A population-based cohort analysis compared the risk of long-term ophthalmic morbidity among children who...
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1272: Sarcopenia in Neurological Patients: Standard Values for Temporal Muscle Thickness and Muscle Strength Evaluation Journal of Clinical Medicine doi: 10.3390/jcm9051272 Authors: Ariane Steindl Johannes Leitner Matthias Schwarz Karl-Heinz Nenning Ulrika Asenbaum Sophie Mayer Ramona Woitek Michael Weber Veronika Schöpf Anna S. Berghoff Thomas Berger Georg Widhalm Daniela Prayer Matthias Preusser Julia Furtner Temporal muscle...
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1269: The Ocular Surface and the Coronavirus Disease 2019: Does a Dual ‘Ocular Route’ Exist? Journal of Clinical Medicine doi: 10.3390/jcm9051269 Authors: Pietro Emanuele Napoli Matteo Nioi Ernesto d’Aloja Maurizio Fossarello Coronavirus disease 2019 (COVID-19) is an important health problem that was defined as a pandemic by the World Health Organization on 11 March 2020. Although great concern has been expressed about COVID-19 infection acquired through ocular...
Tue Apr 28, 2020 03:00
JCM, Vol. 9, Pages 1270: Topical VEGF-C/D Inhibition Prevents Lymphatic Vessel Ingrowth into Cornea but Does Not Improve Corneal Graft Survival Journal of Clinical Medicine doi: 10.3390/jcm9051270 Authors: Ann-Charlott Salabarria Manuel Koch Alfrun Schönberg Elisabeth Zinser Deniz Hos Matthias Hamdorf Thomas Imhof Gabriele Braun Claus Cursiefen Felix Bock Vascular endothelial growth factor-C/D (VEGF-C/D) regulates lymphangiogenesis. Ingrowth of lymphatic vessels...
Tue Apr 28, 2020 03:00
JPM, Vol. 10, Pages 31: Application of Machine Learning Technique to Distinguish Parkinson’s Disease Dementia and Alzheimer’s Dementia: Predictive Power of Parkinson’s Disease-Related Non-Motor Symptoms and Neuropsychological Profile Journal of Personalized Medicine doi: 10.3390/jpm10020031 Authors: Byeon In order to develop a predictive model that can distinguish Parkinson's disease dementia (PDD) from other dementia types, such as Alzheimer's dementia (AD), it is necessary to evaluate...
Tue Apr 28, 2020 03:00
Life, Vol. 10, Pages 53: A New Record for Microbial Perchlorate Tolerance: Fungal Growth in NaClO4 Brines and its Implications for Putative Life on Mars Life doi: 10.3390/life10050053 Authors: Jacob Heinz Tim Krahn Dirk Schulze-Makuch The habitability of Mars is strongly dependent on the availability of liquid water, which is essential for life as we know it. One of the few places where liquid water might be found on Mars is in liquid perchlorate brines that could form via deliquescence....
Tue Apr 28, 2020 03:00
Medicina, Vol. 56, Pages 216: Open-Healing Socket Preservation with a Novel Dense Polytetrafluoroethylene (dPTFE) Membrane: A Retrospective Clinical Study Medicina doi: 10.3390/medicina56050216 Authors: Zafiropoulos Kačarević Qasim Trajkovski Background and objectives: Non-resorbable dense polytetrafluoroethylene (dPTFE) membranes are widely used for regeneration procedures, alone or in combination with particulate materials. The aim of this work was to examine the efficacy...
Tue Apr 28, 2020 03:00
Medicina, Vol. 56, Pages 215: Evaluation of TP-E Interval and TP-E/QT Ratio in Panic Disorder Medicina doi: 10.3390/medicina56050215 Authors: Afsin Asoğlu Orum Cicekci Background and Objectives: The autonomic nervous system (ANS) is involved in panic disorders. ANS dysfunction has been shown to be associated with ventricular arrhythmia and increased heterogeneity of ventricular repolarization. However, there remains limited evidence of the relationship between panic disorders...
Tue Apr 28, 2020 03:00
Medicina, Vol. 56, Pages 214: Management of Hypothyroidism in Patients with Acute Myocardial Infarction Medicina doi: 10.3390/medicina56050214 Authors: Danielle Eagan Gabriela Spencer-Bonilla Spyridoula Maraka Monica Aggarwal Naykky Singh Ospina Background and Objectives: Thyroid hormones (TH) affect cardiac function through effects on cardiac contractility and systemic vascular resistance. While TH replacement for patients with hypothyroidism might be necessary for restoration...
Tue Apr 28, 2020 03:00
Medicines, Vol. 7, Pages 23: Uncharted Source of Medicinal Products: The Case of the Hedychium Genus
Medicines, Vol. 7, Pages 23: Uncharted Source of Medicinal Products: The Case of the Hedychium Genus Medicines doi: 10.3390/medicines7050023 Authors: Wilson R. Tavares Maria do Carmo Barreto Ana M. L. Seca A current research topic of great interest is the study of the therapeutic properties of plants and of their bioactive secondary metabolites. Plants have been used to treat all types of health problems from allergies to cancer, in addition to their use in the perfumery industry...
Tue Apr 28, 2020 03:00
Membranes, Vol. 10, Pages 84: Oily Wastewater Treatment Using Polyamide Thin Film Composite Membrane Technology Membranes doi: 10.3390/membranes10050084 Authors: Sarah Elhady Mohamed Bassyouni Ramadan A. Mansour Medhat H. Elzahar Shereen Abdel-Hamid Yasser Elhenawy Mamdou Y. Saleh In this study, polyamide (PA) thin film composite (TFC) reverse osmosis (RO) membrane filtration was used in edible oil wastewater emulsion treatment. The PA-TFC membrane was characterized...
Tue Apr 28, 2020 03:00
Membranes, Vol. 10, Pages 83: Facilitated Structure Formation in Isoporous Block Copolymer Membranes upon Controlled Evaporation by Gas Flow Membranes doi: 10.3390/membranes10050083 Authors: Kirti Sankhala Joachim Koll Volker Abetz The conventional fabrication of isoporous membranes via the evaporation-induced self-assembly of block copolymers in combination with non-solvent induced phase separation (SNIPS) is achieved under certain environmental conditions. In this study, we report...
Tue Apr 28, 2020 03:00
Membranes, Vol. 10, Pages 82: Polyimide/Ionic Liquid Composite Membranes for Middle and High Temperature Fuel Cell Application: Water Sorption Behavior and Proton Conductivity Membranes doi: 10.3390/membranes10050082 Authors: Kateryna Fatyeyeva Sergiy Rogalsky Stanislav Makhno Oksana Tarasyuk Jorge Arturo Soto Puente Stéphane Marais Four water insoluble room-temperature protic ionic liquids (PILs) based on the N-alkylimidazolium cation with the alkyl chain length from...
Tue Apr 28, 2020 03:00
Metabolites, Vol. 10, Pages 175: An LC–MS Assay to Measure Superoxide Radicals and Hydrogen Peroxide in the Blood System Metabolites doi: 10.3390/metabo10050175 Authors: Ioannis Tsamesidis Chinedu O. Egwu Pierre Pério Jean-Michel Augereau Françoise Benoit-Vical Karine Reybier Red blood cells are constantly exposed to reactive species under physiological or pathological conditions or during administration of xenobiotics. Regardless of the source, its accurate quantification...
Tue Apr 28, 2020 03:00
Microorganisms, Vol. 8, Pages 645: Special Issue: Antimicrobial Resistance in Livestock Microorganisms doi: 10.3390/microorganisms8050645 Authors: Kim Stanford Antimicrobial resistance threatens the health of both humans and livestock as antimicrobials become continually less effective for controlling infectious disease [...]
Tue Apr 28, 2020 03:00
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