Abstract Purpose Cetuximab (CTX) has been used to treat metastatic colorectal cancer (mCRC) with wild-type (wt) RAS and BRAF genes. Meanwhile HER2 amplification reportedly denoted CTX-resistant mCRC tumors. We investigated whether monitoring of HER2 amplification in circulating DNA allowed early detection of mCRC progression and CTX resistance. Methods ...
Tue Apr 28, 2020 18:14
Η Ελληνική Φαρμακοβιομηχανία ELPEN χρηματοδοτεί την κλινική μελέτη GRECCO-19, που διερευνά τη δραστική ουσία κολχικίνη ως μια ενδεχόμενη απάντηση για την αντιμετώπιση της πανδημίας από τον COVID-19. Η έκβαση της μάχης ενάντια στον κορωνοϊό θα σηματοδοτήσει την επόμενη μέρα για τη χώρα μας, αλλά και διεθνώς. Η ELPEN ενισχύει αποφασιστικά το δύσκολο αυτό αγώνα, αποδεικνύοντας έμπρακτα τη σταθερή και διαχρονική προσήλωσή της στην αξία της έρευνας. Με βαθιά πίστη στο επιστημονικό δυναμικό της χώρας...
Tue Apr 28, 2020 15:10
Η επιδημία του νέου κορωνοϊού και η μεγάλη του μεταδοτικότητα έχουν εγείρει έντονες ανησυχίες σχετικά με την καθημερινότητά μας και τι πρέπει να προσέχουμε. Ρούχα, παπούτσια, μαλλιά… όλα στο μεγεθυντικό φακό για να διαπιστωθεί αν τελικά μπορούν να μας μολύνουν με τον SARS-CoV-2. Στο πλαίσιο αυτό, ερωτήματα έχουν προκύψει σχετικά με τη σχέση του ιού και τα μάτια. Με την επιστημονική κοινότητα να μην έχει καταλήξει σε κάποιο κοινό πόρισμα, ανακοινώνονται συνεχώς νέες οδηγίες. Ο David Chu, επίκουρος...
Tue Apr 28, 2020 13:06
Έχασε τον αγώνα ποδοσφαίρου η αγαπημένη σας ομάδα; Αν είχατε στοιχηματίσει με φίλους και χάσατε, είναι το λιγότερο που μπορεί να συνέβη, σύμφωνα με νέα επιστημονικά ευρήματα. Οι ποδοσφαιρικές ήττες μπορούν να βλάψουν σοβαρά την υγεία των φιλάθλων, απειλώντας την έως και με έμφραγμα, διατείνεται έρευνα που δημοσιεύτηκε στο EAPC Essentials 4 You, μια επιστημονική πλατφόρμα της Ευρωπαϊκής Εταιρείας Καρδιολογίας. Οι ερευνητές εξέτασαν τη σχέση ανάμεσα στις αγωνιστικές επιδόσεις της ομάδας Jagiellonia...
Tue Apr 28, 2020 08:24
The original version of this article unfortunately contained a mistake. The second sentence of the section “irAEs and ICI efficacy” should read as.
Tue Apr 28, 2020 03:00
Abstract The effectual clinical benefits of immune checkpoint inhibitor (ICI) are hampered by a high rate of innate resistance, and VEGFA may contribute to ICI treatment resistance. In this study, we endeavored to assess the tumor microenvironment (TME) in VEGFA-overexpressed human tumors and mouse tumor models, and to explore whether anti-angiogenesis therapy can overcome the innate resistance to ICI in hyperangiogenesis mouse tumor models and the underlying mechanism. Effect...
Tue Apr 28, 2020 03:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00218F, Critical ReviewKyubong Jo, Xuelin Jin, Natalia Diyah Hapsari, Seunghyun LeeDNA binding fluorescent proteins are useful probes for a broad range of biological applications. Fluorescent protein (FP)-tagging allows DNA binding proteins expressed within a living cell to be directly visualized,...The content of this RSS Feed (c) The Royal Society of Chemistry
Tue Apr 28, 2020 02:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00038H, Paperfengjuan Ding, Yameng Zhao, Haiyan Liu, Weibing ZhangSelective, sensitive and efficient phosphopeptide enrichment is significant in understanding phosphorylation-regulated processes and finding potential biomarkers. Magnetic materials have significant advantages for the separation and enrichment of modified peptides and...The content of this RSS Feed (c) The Royal Society of Chemistry
Tue Apr 28, 2020 02:00
Analyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN00272K, Critical ReviewAswin Verhoeven, Martin Giera, Oleg A MayborodaProviding maximum information on the provenance of scientific results in life sciences is getting considerable attention since the widely publicized reproducibility crisis. Improving the reproducibility of data processing and analysis...The content of this RSS Feed (c) The Royal Society of Chemistry
Tue Apr 28, 2020 02:00
Publication date: Available online 27 April 2020Source: Allergologia et ImmunopathologiaAuthor(s): Alshymaa A. Ahmed, Alia A. El Shahaway, Sameh A. Hussien
Tue Apr 28, 2020 18:01
The author names and family names of the originally published article was inversed. Correct presentation is presented here.
Tue Apr 28, 2020 18:00
Abstract Purpose To develop and validate an integrated model for discriminating tumor recurrence from radiation necrosis in glioma patients. Methods Data from 160 pathologically confirmed glioma patients were analyzed. The diagnostic model was developed in a primary cohort (n = 112). Textural features were extracted from postoperative...
Tue Apr 28, 2020 18:00
The Table 2 in the original version of this article contained a mistake in the alignment. Correct Table 2 presentation is presented here.
Tue Apr 28, 2020 18:00
Funding information from the original version of this article was incomplete. Complete information is presented here.
Tue Apr 28, 2020 18:00
Abstract Purpose The purpose of this study was to perform a prospective integrated analysis of 18F-fluorodeoxyglucose (18F-FDG)-positron emission tomography (PET)/computed tomography (CT) and circulating tumor DNA (ctDNA) to assess responses to multimodal chemotherapy in children and adolescents suffering from Ewing sarcoma (EwS). Methods ...
Tue Apr 28, 2020 18:00
The correct administered activity of 18F-FCH is 0.1–0.14 mCi/Kg, which is equivalent to 3.7–5.2 MBq/kg.
Tue Apr 28, 2020 18:00
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Tue Apr 28, 2020 18:00
Publication date: Available online 27 April 2020Source: Journal of the American College of SurgeonsAuthor(s): Julie Grossman, Andrew Pierce, Jessica Mody, Jason Gagne, Carol Sykora, Sena Sayood, Susan Cook, Nirah Shomer, Stephen Y. Liang, Shaina Eckhouse
Tue Apr 28, 2020 17:43
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Xinyu Wang, Liangshu Feng, Meiying Xin, Yulei Hao, Xu Wang, Pei Shang, Mingming Zhao, Shuai Hou, Yunhai Zhang, Yun Xiao, Di Ma, Jiachun Feng
Tue Apr 28, 2020 17:39
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Yuan Yuan, Jinhui Zhou, Yanfen Zheng, Zongchang Xu, Yiqiang Li, San Zhou, Chengsheng Zhang
Tue Apr 28, 2020 17:39
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Li Xiaobing, Jiang Yan, Zhang Wangping, Zhang Rufang, Li Jia, Wei Rong
Tue Apr 28, 2020 17:39
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Violina Kakoty, Sarathlal K C, Ruei-Dun Tang, Chih Hao Yang, Sunil Kumar Dubey, Rajeev Taliyan
Tue Apr 28, 2020 17:39
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Yahyea Baktiar Laskar, Pranab Behari Mazumder
Tue Apr 28, 2020 17:39
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Zahra Ilyas, Simone Perna, Salwa Al-thawadi, Tariq A. Alalwan, Antonella Riva, Giovanna Petrangolini, Clara Gasparri, Vittoria Infantino, Gabriella Peroni, Mariangela Rondanelli
Tue Apr 28, 2020 17:39
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Zhifeng Huang, Donglin Zhuang, Bing Xiong, David Xingfei Deng, Hanhua Li, Wen Lai
Tue Apr 28, 2020 17:39
Publication date: July 2020Source: Biomedicine & Pharmacotherapy, Volume 127Author(s): Yuanchun Yue, Kai Ye, Jing Lu, Xinyu Wang, Shuwen Zhang, Liu Liu, Baoyu Yang, Khaled Nassar, Xiaoxi Xu, Xiaoyang Pang, Jiaping Lv
Tue Apr 28, 2020 17:39
Publication date: June 2020Source: European Journal of Cancer, Volume 132Author(s): Koen J. Hartemink, Alexander C.J. van Akkooi, Aletta P.I. Houwink, Emile E. Voest
Tue Apr 28, 2020 17:30
Publication date: June 2020Source: European Journal of Cancer, Volume 132Author(s): Eileen M. O'Reilly, Diletta Barone, Devalingam Mahalingam, Tanios Bekaii-Saab, Spencer H. Shao, Julie Wolf, Molly Rosano, Silva Krause, Donald A. Richards, Kenneth H. Yu, James M. Roach, Keith T. Flaherty, David P. Ryan
Tue Apr 28, 2020 17:30
Mucosal Immunology, Published online: 28 April 2020; doi:10.1038/s41385-020-0286-6Th22 cells are efficiently recruited in the gut by CCL28 as an alternative to CCL20 but do not compensate for the loss of Th17 cells in treated HIV-1-infected individuals
Tue Apr 28, 2020 03:00
Publication date: Available online 27 April 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Daniela Adamo, Roberta Gasparro, Gaetano Marenzi, Massimo Mascolo, Mariarosaria Cervasio, Giuseppe Cerciello, Danilo De Novellis, Michele Davide Mignogna
Tue Apr 28, 2020 17:28
Publication date: Available online 26 April 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Nicole Topilow, Ying Chen, David T. Tse, David T. Tse
Tue Apr 28, 2020 17:28
Publication date: Available online 26 April 2020Source: Journal of Oral and Maxillofacial SurgeryAuthor(s): Tae-Geon Kwon, Michael Miloro, Michael D. Han, Tae-Geon Kwon
Tue Apr 28, 2020 17:28
Publication date: Available online 28 April 2020Source: Radiotherapy and OncologyAuthor(s): Eric J. Lehrer, Amar U. Kishan, James B. Yu, Daniel M. Trifiletti, Timothy N. Showalter, Rodney Ellis, Nicholas G. Zaorsky
Tue Apr 28, 2020 17:25
Publication date: Available online 27 April 2020Source: Radiotherapy and OncologyAuthor(s): Juanita M. Crook, Chad Tang, Howard Thames, Pierre Blanchard, Jeremiah Sanders, Jay Ciezki, Mira Keyes, W. James Morris, Gregory Merrick, Charles Catton, Hamid Raziee, Richard Stock, Frank Sullivan, Mitch Anscher, Jeremy Millar, Steven Frank
Tue Apr 28, 2020 17:25
Publication date: Available online 27 April 2020Source: Radiotherapy and OncologyAuthor(s): Geert O. Janssens, Henry C. Mandeville, Beate Timmermann, John H. Maduro, Claire Alapetite, Laetitia Padovani, Gail Horan, Yasmin Lassen-Ramshad, Karin Dieckmann, Christian Ruebe, Nicky Thorp, Lorenza Gandola, Thankamma Ajithkumar, Tom Boterberg
Tue Apr 28, 2020 17:25
Publication date: Available online 27 April 2020Source: Radiotherapy and OncologyAuthor(s): Yasir Alayed, Harvey Quon, Aldrich Ong, Patrick Cheung, William Chu, Hans Chung, Danny Vesprini, Amit Chowdhury, Dilip Panjwani, Geordi Pang, Renee Korol, Melanie Davidson, Ananth Ravi, Boyd McCurdy, Liying Zhang, Alexandre Mamedov, Andrea Deabreu, Andrew Loblaw
Tue Apr 28, 2020 17:25
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