Cancers, Vol. 12, Pages 1091: The Circular RNA Landscape of Non-Small Cell Lung Cancer Cells Cancers doi: 10.3390/cancers12051091 Authors: Nele Van Der Steen Yanhong Lyu Anne K. Hitzler Andrea C. Becker Jeanette Seiler Sven Diederichs The class of circular RNA (circRNA) is characterized by head-to-tail bonds between exons formed by backsplicing. Here, we provide a resource of circRNA expression in a comprehensive panel of 60 lung cancer and non-transformed cell lines (FL3C...
Tue Apr 28, 2020 03:00
Cells, Vol. 9, Pages 1094: The Role of Crosstalk between AR3 and E2F1 in Drug Resistance in Prostate Cancer Cells Cells doi: 10.3390/cells9051094 Authors: Jin Xu Xi Yang Dhanraj Deshmukh Hegang Chen Shengyun Fang Yun Qiu Background: Drug resistance is one of the most prevalent causes of death in advanced prostate cancer patients. Combination therapies that target cancer cells via different mechanisms to overcome resistance have gained increased attention in recent years....
Tue Apr 28, 2020 03:00
Cells, Vol. 9, Pages 1093: ONX 0914 Lacks Selectivity for the Cardiac Immunoproteasome in CoxsackievirusB3 Myocarditis of NMRI Mice and Promotes Virus-Mediated Tissue Damage Cells doi: 10.3390/cells9051093 Authors: Neumaier Harel Klingel Kaya Heuser Kespohl Beling : Inhibition of proteasome function by small molecules is highly efficacious in cancer treatment. Other than non-selective proteasome inhibitors, immunoproteasome-specific inhibitors allow for specific...
Tue Apr 28, 2020 03:00
Cells, Vol. 9, Pages 1095: Genome Editing of the SNAI1 Gene in Rhabdomyosarcoma: A Novel Model for Studies of Its Role Cells doi: 10.3390/cells9051095 Authors: Aleksandra Ulman Klaudia Skrzypek Paweł Konieczny Claudio Mussolino Toni Cathomen Marcin Majka Genome editing (GE) tools and RNA interference technology enable the modulation of gene expression in cancer research. While GE mediated by clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 or transcription...
Tue Apr 28, 2020 03:00
Cells, Vol. 9, Pages 1091: Microbial Alterations and Risk Factors of Breast Cancer: Connections and Mechanistic Insights Cells doi: 10.3390/cells9051091 Authors: Parida Sharma Breast cancer-related mortality remains high worldwide, despite tremendous advances in diagnostics and therapeutics; hence, the quest for better strategies for disease management, as well as the identification of modifiable risk factors, continues. With recent leaps in genomic technologies, microbiota have...
Tue Apr 28, 2020 03:00
Cells, Vol. 9, Pages 1092: Cardiomyocyte-Specific Deletion of Orai1 Reveals Its Protective Role in Angiotensin-II-Induced Pathological Cardiac Remodeling Cells doi: 10.3390/cells9051092 Authors: Sebastian Segin Michael Berlin Christin Richter Rebekka Medert Veit Flockerzi Paul Worley Marc Freichel Juan E. Camacho Londoño Pathological cardiac remodeling correlates with chronic neurohumoral stimulation and abnormal Ca2+ signaling in cardiomyocytes. Store-operated calcium...
Tue Apr 28, 2020 03:00
Cells, Vol. 9, Pages 1089: RNA Interference Screening Identifies Novel Roles for RhoBTB1 and RhoBTB3 in Membrane Trafficking Events in Mammalian Cells Cells doi: 10.3390/cells9051089 Authors: Maeve Long Tilen Kranjc Margaritha M. Mysior Jeremy C. Simpson In the endomembrane system of mammalian cells, membrane traffic processes require a high degree of regulation in order to ensure their specificity. The range of molecules that participate in trafficking events is truly vast,...
Tue Apr 28, 2020 03:00
Cells, Vol. 9, Pages 1088: Calcium-Free and Cytochalasin B Treatment Inhibits Blastomere Fusion in 2-Cell Stage Embryos for the Generation of Floxed Mice via Sequential Electroporation Cells doi: 10.3390/cells9051088 Authors: Takuro Horii Ryosuke Kobayashi Mika Kimura Sumiyo Morita Izuho Hatada The generation of conditional knockout mice using the Cre-loxP system is advantageous for the functional analysis of genes. Flanked by two loxP sites (floxed) mice can be directly...
Tue Apr 28, 2020 03:00
Cells, Vol. 9, Pages 1087: The Spindle Assembly Checkpoint Functions during Early Development in Non-Chordate Embryos Cells doi: 10.3390/cells9051087 Authors: Janet Chenevert Marianne Roca Lydia Besnardeau Antonella Ruggiero Dalileh Nabi Alex McDougall Richard R. Copley Elisabeth Christians Stefania Castagnetti In eukaryotic cells, a spindle assembly checkpoint (SAC) ensures accurate chromosome segregation, by monitoring proper attachment of chromosomes to spindle...
Tue Apr 28, 2020 03:00
Cells, Vol. 9, Pages 1090: Modulation of mTORC1 Signaling Pathway by HIV-1 Cells doi: 10.3390/cells9051090 Authors: Burkitkan Akbay Anna Shmakova Yegor Vassetzky Svetlana Dokudovskaya Mammalian target of rapamycin complex 1 (mTORC1) is a master regulator of cellular proliferation and survival which controls cellular response to different stresses, including viral infection. HIV-1 interferes with the mTORC1 pathway at every stage of infection. At the same time, the host cells...
Tue Apr 28, 2020 03:00
Cells, Vol. 9, Pages 1086: Radiation Potentiates Monocyte Infiltration into Tumors by Ninjurin1 Expression in Endothelial Cells Cells doi: 10.3390/cells9051086 Authors: Ju-Hee Kang Jong Kyu Woo Yeong-Su Jang Seung Hyun Oh Radiation is a widely used treatment for cancer patients, with over half the cancer patients receiving radiation therapy during their course of treatment. Considerable evidence from both preclinical and clinical studies show that tumor recurrence gets restored...
Tue Apr 28, 2020 03:00
Clean Technol., Vol. 2, Pages 156-169: Using Self-Organizing Maps to Elucidate Patterns among Variables in Simulated Syngas Combustion Clean Technologies doi: 10.3390/cleantechnol2020011 Authors: Dhan Lord B. Fortela Matthew Crawford Alyssa DeLattre Spencer Kowalski Mary Lissard Ashton Fremin Wayne Sharp Emmanuel Revellame Rafael Hernandez Mark Zappi This study focused on demonstrating the use of a self-organizing map (SOM) algorithm to elucidate patterns among...
Tue Apr 28, 2020 03:00
Diagnostics, Vol. 10, Pages 261: Development of a Deep-Learning-Based Artificial Intelligence Tool for Differential Diagnosis between Dry and Neovascular Age-Related Macular Degeneration Diagnostics doi: 10.3390/diagnostics10050261 Authors: Tae-Young Heo Kyoung Min Kim Hyun Kyu Min Sun Mi Gu Jae Hyun Kim Jaesuk Yun Jung Kee Min The use of deep-learning-based artificial intelligence (AI) is emerging in ophthalmology, with AI-mediated differential diagnosis of neovascular...
Tue Apr 28, 2020 03:00
Diagnostics, Vol. 10, Pages 259: Bilateral Acute Macular Neuroretinopathy in a Young Patient: Imaging and Visual Field during Two-Year-Follow-Up Diagnostics doi: 10.3390/diagnostics10050259 Authors: Alessandro Porta Sarah Tripodi Mario Damiano Toro Robert Rejdak Konrad Rejdak Emma Clara Zanzottera Fabio Ferentini Acute macular neuroretinopathy (AMN) is a rare disorder. We report a case of bilateral AMN in a young female patient, without any risk factors. She referred...
Tue Apr 28, 2020 03:00
Diagnostics, Vol. 10, Pages 260: Impact of Gene Polymorphisms in GAS5 on Urothelial Cell Carcinoma Development and Clinical Characteristics Diagnostics doi: 10.3390/diagnostics10050260 Authors: Wei-Chun Weng Chih-Jung Chen Pei-Ni Chen Shian-Shiang Wang Ming-Ju Hsieh Shun-Fa Yang Urothelial cell carcinoma (UCC) is the commonest malignant tumor of the urinary tract and the second most common kidney cancer malignancy. Growth arrest-specific 5 (GAS5), a long noncoding RNA,...
Tue Apr 28, 2020 03:00
Diversity, Vol. 12, Pages 174: Freshwater Mussel Bed Habitat in an Alluvial Sand-Bed-Material-Dominated Large River: A Core Flow Sediment Refugium? Diversity doi: 10.3390/d12050174 Authors: Alan D. Christian Andrew J. Peck Ryan Allen Raven Lawson Waylon Edwards Grace Marable Sara Seagraves John L. Harris Habitat degradation, organismal needs, and other effects influencing freshwater mussel declines have been subject to intense focus by conservationists for the last...
Tue Apr 28, 2020 03:00
Diversity, Vol. 12, Pages 173: Morphological Disparity of the Humerus in Modern Birds Diversity doi: 10.3390/d12050173 Authors: Francisco J. Serrano Mireia Costa-Pérez Guillermo Navalón Alberto Martín-Serra From a functional standpoint, the humerus is a key element in the skeleton of vertebrates as it is the forelimb’s bone that connects with the pectoral girdle. In most birds, the humerus receives both the forces exerted by the main flight muscles and the aerodynamical...
Tue Apr 28, 2020 03:00
Diversity, Vol. 12, Pages 172: Fungal Diversity in the Phyllosphere of Pinus heldreichii H. Christ—An Endemic and High-Altitude Pine of the Mediterranean Region Diversity doi: 10.3390/d12050172 Authors: Jelena Lazarević Audrius Menkis Pinus heldreichii is a high-altitude coniferous tree species naturaly occurring in small and disjuncted populations in the Balkans and southern Italy. The aim of this study was to assess diversity and composition of fungal communities in living needles...
Tue Apr 28, 2020 03:00
Fractal Fract, Vol. 4, Pages 18: Multi-Strip and Multi-Point Boundary Conditions for Fractional Langevin Equation Fractal and Fractional doi: 10.3390/fractalfract4020018 Authors: Ahmed Salem Balqees Alghamdi In the present paper, we discuss a new boundary value problem for the nonlinear Langevin equation involving two distinct fractional derivative orders with multi-point and multi-nonlocal integral conditions. The fixed point theorems for Schauder and Krasnoselskii–Zabreiko...
Tue Apr 28, 2020 03:00
Geriatrics, Vol. 5, Pages 27: A Systematic Review Examining Associations between Cardiovascular Conditions and Driving Outcomes among Older Drivers Geriatrics doi: 10.3390/geriatrics5020027 Authors: Ganesh M. Babulal Ramana Kolady Sarah H. Stout Catherine M. Roe There is a vast literature on stroke as a cardiovascular disease and driving outcomes, however little is known about other cardiovascular conditions and driving. The purpose of this review is to examine the literature...
Tue Apr 28, 2020 03:00
Healthcare, Vol. 8, Pages 116: Immediate Effects of Ankle–Foot Orthosis Using Wire on Static Balance of Patients with Stroke with Foot Drop: A Cross-Over Study Healthcare doi: 10.3390/healthcare8020116 Authors: Lee Choi Choi The aim of this study was to investigate the immediate static balance effects of bare foot, UD-Flex ankle–foot orthosis (AFO), and AFO using wire (AOW) of patients with stroke with foot drop. Seventeen patients with stroke with foot drop (8 men...
Tue Apr 28, 2020 03:00
Healthcare, Vol. 8, Pages 115: Community-Based Healthcare for Migrants and Refugees: A Scoping Literature Review of Best Practices Healthcare doi: 10.3390/healthcare8020115 Authors: Elena Riza Shona Kalkman Alexandra Coritsidis Sotirios Koubardas Sofia Vassiliu Despoina Lazarou Panagiota Karnaki Dina Zota Maria Kantzanou Theodora Psaltopoulou Athena Linos Background: Strengthening community-based healthcare is a valuable strategy to reduce health inequalities...
Tue Apr 28, 2020 03:00
Healthcare, Vol. 8, Pages 114: The Impact of Nurse Practitioners on Hospitalizations and Discharges from Long-term Nursing Facilities: A Systematic Review Healthcare doi: 10.3390/healthcare8020114 Authors: Michael Mileski Upwinder Pannu Bobbi Payne Erica Sterling Rebecca McClay The objective of this study was to increase the understanding of the role a nurse practitioner (NP) has in reducing the risk of hospitalizations and improving quality outcomes among nursing facility...
Tue Apr 28, 2020 03:00
Healthcare, Vol. 8, Pages 113: The Effects of Long-Term 40-Hz Physioacoustic Vibrations on Motor Impairments in Parkinson’s Disease: A Double-Blinded Randomized Control Trial Healthcare doi: 10.3390/healthcare8020113 Authors: Abdullah Mosabbir Quincy J. Almeida Heidi Ahonen Recent studies have suggested that vibration therapy may have a positive influence in treating motor symptoms of Parkinson’s disease (PD). However, quantitative evidence of the benefits of vibration...
Tue Apr 28, 2020 03:00
Humanities, Vol. 9, Pages 36: Historicizing Migration and Displacement: Learning from the Early Roman Empire in the Time of the Nation-State. Response to Lachenicht, Susanne. Learning from Past Displacements? The History of Migrations between Historical Specificity, Presentism and Fractured Continuities. Humanities 2018, 7, 36 Humanities doi: 10.3390/h9020036 Authors: George Baroud My response to Susanne Lachenicht’s thought-provoking article is a brief attempt to take up her...
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IJERPH, Vol. 17, Pages 3066: Prevalence of Physical Activity and Sedentary Behavior among Chinese Children and Adolescents: Variations, Gaps, and Recommendations International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093066 Authors: Hejun Shen Jin Yan Jin-Tao Hong Cain Clark Xian-Nan Yang Yang Liu Si-Tong Chen Physical-activity (PA) and sedentary-behavior (SB) assessment is of particular importance in the promotion of health in young...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3061: Factors Obscuring the Role of E. coli from Domestic Animals in the Global Antimicrobial Resistance Crisis: An Evidence-Based Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093061 Authors: Fernanda Loayza Jay P. Graham Gabriel Trueba Recent studies have found limited associations between antimicrobial resistance (AMR) in domestic animals (and animal products), and AMR in human clinical settings. These studies...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3082: Twenty-Year Span of Global Coronavirus Research Trends: A Bibliometric Analysis International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093082 Authors: Yi Zhou Liyu Chen The coronavirus disease 2019 (COVID-19) pandemic aroused global public concern and became a major medical issue. This study aims to investigate the global research routine and trends of coronavirus over the last twenty years based on the production, hotspots,...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3065: Validity and Reliability of the Korean Version of the Anesthesia Surrendering Instrument International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093065 Authors: Hanna Lee Ji-Soon Kang Jeong-Won Han This study examined the reliability and validity of the Korean version of the anesthesia surrendering instrument (ASI), which was originally developed to measure anesthesia surrendering in Swedish adults. The study population...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3080: How Employee’s Leadership Potential Leads to Leadership Ostracism Behavior: The Mediating Role of Envy, and the Moderating Role of Political Skills International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093080 Authors: Ying Xue Xiyuan Li Hongmei Wang Qiu Zhang Recently, research on the leadership potential of employees has gradually attracted the attention of scholars. However, further exploration is required to better...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3081: Relevant Work Factors Associated with Voice Disorders in Early Childhood Teachers: A Comparison between Kindergarten and Elementary School Teachers in Yancheng, China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093081 Authors: Yaping Tao Charles Tzu-Chi Lee Yih-Jin Hu Qiang Liu Background: Early childhood teachers consist of kindergarten and elementary school teachers in the lower grades. Young children...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3078: Application of an Enhanced Version of Recursive Operability Analysis for Combustible Dusts Risk Assessment International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093078 Authors: Barozzi Copelli Scotton Torretta Organic dust explosions were and are still today a critical issue in the food, pharmaceutical, and fine chemical industry. Materials such as flour, corn starch, sugar and APIs represent a cause of severe...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3079: Do Health Insurance Schemes Heterogeneously Affect Income and Income Distribution? Evidence from Chinese Agricultural Migrants Survey International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093079 Authors: Lu Wang Wei Currently, the particularity of Chinese agricultural migrants groups determines that they can participate in various types of public health insurance schemes, i.e., the New Cooperative Medical Scheme (NCMS),...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3076: Racial Disparities in Associations between Neighborhood Demographic Polarization and Birth Weight International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093076 Authors: Fong Yitshak-Sade Lane Fabian Kloog Schwartz Coull Koutrakis Hart Laden Zanobetti Neighborhood demographic polarization, or the extent to which a privileged population group outnumbers a deprived group, can affect health...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3075: Multi-Agent-Based Urban Vegetation Design International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093075 Authors: Ali Song Lee Kim Ali Urban vegetation is an essential element of the urban city pedestrian walkway. Despite city forest regulations and urban planning best practices, vegetation planning lacks clear comprehension and compatibility with other urban elements surrounding it. Urban planners and academic...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3077: The “Obiettivo Antibiotico” Campaign on Prudent Use of Antibiotics in Sicily, Italy: The Pilot Phase International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093077 Authors: Barchitta Quattrocchi Maugeri Rosa Mastra Basile Giuffrida Rinaldi Murolo Agodi The issue of antimicrobial resistance (AMR) is a focus of the World Health Organization, which proposes educational interventions targeting...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3073: Qualitative Evaluation of the STOEMP Network in Ghent: An Intersectoral Approach to Make Healthy and Sustainable Food Available to All International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093073 Authors: Vos Romeo-Velilla Stegeman Bell Vliet Lippevelde The STOEMP network is, to our knowledge, one of the first initiatives to bring different sectors together in a municipality so as to increase accessibility...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3074: Insulation and Evaporative Resistance of Clothing for Sugarcane Harvesters and Chemical Sprayers, and their Application in PHS Model-Based Exposure Predictions International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093074 Authors: Kuklane Toma Lucas Many workers are exposed to heat stress that can be exacerbated by the type of clothing they wear. The resulted heat strain can lead to short or long-term heat-related...
Tue Apr 28, 2020 03:00
IJERPH, Vol. 17, Pages 3071: An Inventory of European Birth Cohorts International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17093071 Authors: Pansieri Pandolfini Clavenna Choonara Bonati Many birth cohorts have been carried out. We performed a review of European birth cohorts to see the countries involved, provide a panorama of the current research topics and design, and, more generally, provide input for those creating collaborations and...
Tue Apr 28, 2020 03:00
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