Abstract Objectives Sealer remnants in the access cavity may negatively affect coronal seal and cause tooth discoloration. This study sought to evaluate the efficacy of different cleaning protocols for the sealer-contaminated access cavity. Materials and methods Sixty extracted human molars were accessed, chemomechanically prepared and warm vertically obturated...
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Salisbury asks what we might learn from the covid-19 pandemic.1 At times like this, we have to make it up as we go along. There isn’t time to go through the hoops of obtaining official permission to...
12h
bmj;369/apr21_23/m1604/FAF1faDavid William Young was consultant physician at Dudley Road Hospital (now City Hospital) in Birmingham from 1974 to 2002. He was a pioneer in and enthusiast for the...
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bmj;369/apr21_22/m1603/FAF1faBorn in Dar Es Salam, Tanzania, where his parents had moved from Goa in India, Michael Joseph Noronha was the sixth of eight children. The family moved to Pune, India,...
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bmj;369/apr21_21/m1431/FAF1faMalcolm Keith Sykes was one of the most prominent British anaesthetists of the second half of the 20th century. His career extended from 1950 to 1991, a period of major...
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bmj;369/apr21_19/m1602/FAF1faAfter early education at Aberdeen Grammar School, Colin McIntosh went to Aberdeen University to study medicine. Initial house jobs in the Aberdeen Royal Infirmary and in...
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AbstractObjectiveTo evaluate viral loads at different stages of disease progression in patients infected with the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first...
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Salisbury asks what we might learn from the covid-19 pandemic.1 At times like this, we have to make it up as we go along. There isn’t time to go through the hoops of obtaining official permission to...
13h
bmj;369/apr21_23/m1604/FAF1faDavid William Young was consultant physician at Dudley Road Hospital (now City Hospital) in Birmingham from 1974 to 2002. He was a pioneer in and enthusiast for the...
15h
bmj;369/apr21_22/m1603/FAF1faBorn in Dar Es Salam, Tanzania, where his parents had moved from Goa in India, Michael Joseph Noronha was the sixth of eight children. The family moved to Pune, India,...
15h
bmj;369/apr21_21/m1431/FAF1faMalcolm Keith Sykes was one of the most prominent British anaesthetists of the second half of the 20th century. His career extended from 1950 to 1991, a period of major...
15h
bmj;369/apr21_19/m1602/FAF1faAfter early education at Aberdeen Grammar School, Colin McIntosh went to Aberdeen University to study medicine. Initial house jobs in the Aberdeen Royal Infirmary and in...
15h
AbstractObjectiveTo evaluate viral loads at different stages of disease progression in patients infected with the 2019 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during the first...
15h
bmj;369/apr21_18/m1600/FAF1faJohn V Dyer, the district medical officer of health for Lancaster and District from 1968 to 1990, died peacefully at his home in Hest Bank. His funeral service was held...
15h
bmj;369/apr21_16/m1599/FAF1faNorah Campbell came from a primary class of 43 on a York council estate, and reached Lady Margaret Hall and the Oxford clinical school. She loved obstetrics, gained her...
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bmj;369/apr21_17/m1559/FAF1faIn 1995 the government appointed John Pattison chair of its advisory committee on bovine spongiform encephalopathy (BSE). Dubbed “the man who couldn’t lie,” Pattison was...
15h
Protests against stay at home orders, temporary business closures, and other social distancing measures imposed by US state governors have broken out in at least eight states, with the backing of...
16h
In this feature (BMJ 2020;369:m1554, doi:10.1136/bmj.m1554, published 20 April 2020) we incorrectly stated that Ignacio Aguado was a member of the People’s Party rather than the Citizens Party...
16h
As hospitals run out of personal protective equipment (PPE) for frontline healthcare staff fighting the covid-19 pandemic, doctors report that trusts and NHS England are clamping down on their...
16h
Different views may be aired on the timeliness of the government’s overall response to the predictable arrival in the UK of the coronavirus pandemic. Since then, however, there has been, at least in...
16h
The Easter bank holidays were cancelled for general practices at short notice, to take the pressure off out-of-hours services in anticipation of a rise in demand. Most of my patients assumed that we...
17h
My Welsh comprehensive school education stood me in good stead for rugby, but less so for Greek mythology. I may have come late to the classics, but I have recently read about how Theseus defeated...
17h
The coronavirus pandemic has revealed much about public policy, including the extent to which politicians and their advisers rely on modelling to help predict the future of virus spread and decide...
17h
The government is to reintroduce contact tracing of people who have had symptoms of covid-19, England’s health secretary, Matt Hancock, said last week.Hancock told MPs on the health select committee...
17h
Brazil’s president, Jair Bolsonaro, has fired his popular health minister, Luiz Henrique Mandetta, after weeks of conflicting messages from the two men about the risks associated with the covid-19...
18h
More than a quarter of patients with covid-19 on ventilators also need renal support in the form of dialysis, raising concerns that there could be significant supply problems as countries attempt to...
19h
US governors have called on the federal government to help them get more covid-19 testing kits as well as personal protective equipment for healthcare workers after complaining that they were...
20h
The former head of the 2012 Summer Olympics and Paralympics has been appointed to lead the UK’s effort to produce personal protective equipment (PPE) for NHS staff.Paul Deighton will lead a campaign...
20h
What you need to knowThe rescheduling of cannabis-based medicinal products (CBMPs) allows their prescription when there is an unmet clinical needInitial prescription of CBMPs must be made by a doctor...
20h
It is hard to write about the economics of covid-19 while we are grappling with such an unprecedented global emergency. But questions are being voiced—from presidents and commentators to health...
21h
Early GP referrals are associated with cancer patients surviving longer, according to a study looking at 1.4m patients with cancer in England.1Researchers from King’s College London and Public Health...
21h
Public health experts have called for the government to publish the evidence behind the UK’s guidance on self-isolation, which says that people who develop symptoms of covid-19 need only isolate for...
21h
by Subhadip Choudhuri, Nisha Jain Garg Trypanosoma cruzi (T. cruzi) is the etiological agent of Chagas cardiomyopathy. In the present study, we investigated the role of extracellular vesicles (Ev) in shaping the macrophage (Mφ) response in progressive Chagas disease (CD). We purified T. cruzi Ev (TcEv) from axenic parasite cultures, and T. cruzi-induced Ev (TEv) from the supernatants of infected cells and plasma of acutely and chronically infected wild-type and Parp1-/- mice. Cultured (Raw 264.7)...
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Carbon content of Earth’s core Cutaway of Earth showing the core. Image credit: PublicDomainPictures.net/alex grichenko. The total amount of carbon on Earth—the bulk carbon content—is poorly understood due to uncertainty in the amount of carbon in Earth’s core, where most carbon is likely located. To better estimate the carbon content...
12h
RNA has been proposed as an important scaffolding factor in the nucleus, aiding protein complex assembly in the dense intracellular milieu. Architectural contributions of RNA to cytosolic signaling pathways, however, remain largely unknown. Here, we devised a multidimensional gradient approach, which systematically locates RNA components within cellular protein networks. Among...
12h
The phylogenetic tree of boosting has a bushy carriage, with early influencers: Ref. 1 was undoubtedly one for the making and use of popular application packages, some used nowadays in almost every Kaggle competition (2), and in that respect it is an understatement to say that the recent work of...
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Olfaction and thermoregulation are key functions for mammals. The former is critical to feeding, mating, and predator avoidance behaviors, while the latter is essential for homeothermy. Aquatic and amphibious mammals face olfactory and thermoregulatory challenges not generally encountered by terrestrial species. In mammals, the nasal cavity houses a bony system...
12h
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