Mark above section as read
LaryngorhinootologieDOI: 10.1055/a-1177-1199© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents | Full text
LaryngorhinootologieDOI: 10.1055/a-1177-1371 Hintergrund Die Richtungslokalisation ist eine Teilleistung der zentralen auditiven Verarbeitung. Es wurde der Frage nachgegangen, ob das Tragen von Hörgeräten die Lokalisationsfähigkeit von nichtsprachlichen Stimuli bei schwerhörigen Schulkindern unterstützt. Patienten und Methoden 20 Kinder (7–17 Jahre) mit einer beidseitigen, symmetrischen, mittelgradigen peripheren Schallempfindungsschwerhörigkeit (WHO-Grad 2) wurden im Freifeld...
Mark above section as read
Exp Clin Endocrinol DiabetesDOI: 10.1055/a-1158-9248 Caenorhabditis elegans is an established model organism in neurodegeneration and aging research. Oxidative stress and formation of advanced glycation endproducts (AGEs), as they occur under hyperglycemic conditions in diabetes mellitus, contribute to neuronal damage and lifespan reduction. Sulforaphane (SFN) is an indirect antioxidant,...
Mark above section as read
Abstract Fine particulate matter with an aerodynamic diameter less than 2.5 μm (PM2.5) is a serious air pollutant associated with health problems. Macrophages play an important role in the process of PM2.5-induced inflammation in respiratory diseases. However, the detailed mechanism remains unclear. We aimed to examine the mechanism of PM2.5-induced inflammation and find possible anti-inflammatory inhibitors. PM2.5 was collected in Hangzhou,...
Mark above section as read
Soon after he fell ill and went off duty due to his personal struggle with COVID-19, Boris Johnson, prime minister of the United Kingdom, rediscovered society, declaring to the British and global media that there is indeed “really . . . such a thing as society” and that it could and should, moreover, pull together to overcome the global pandemic. As we make our way through it, I find myself frequently turning to Émile Durkheim, but with a focus on his insights into the constitution of collective...
A sense of satisfaction settles in as I sit in the partially constructed herbarium and watch Kipila teach his son how to use the hand lens. Kipila is taking his crash course lessons of botanical identification of plants from the last two weeks and immediately putting them into action by teaching the next generation. He begins by slowly explaining how to adjust the hand lens to the eye and then finding the part of the plant that you want to focus on. His son takes a few minutes to find the distance...
Mark above section as read
New research finds fish diets, not geography, dictate how fast species evolve.
Scientists have developed a way to potentially thwart the spread of a disease-causing bacterium that harms more than hundred plant species worldwide, an advance that could save the nursery industry billions of dollars a year.
Mark above section as read
Tracheotomy is a commonly performed surgical airway to relieve upper airway obstruction, improve pulmonary hygeine, and decrease the risk of damage to the larynx from indwelling endotracheal tubes. Critical Care Intensivists have safely introduced the Percutaneous Dilational Tracheotomy (PDT) into practice, but contraindications and limitations exist for this technique. In patients with indwelling endotracheal tubes who have difficult airways, open surgical tracheotomy is considered advantageous...
Mark above section as read
Abstract Background Vinegar has been recognized as an effective antimicrobial agent for long. This study intended to elucidate the effect of commercially available vinegar on in situ pellicle formation and existing 24-h biofilms. Methods In situ biofilm formation took place on bovine enamel slabs mounted in individual splints and exposed...
Abstract Background This study assessed the direct, indirect and total effect of distal – political - risk indicators (affecting populations), and proximal risk indicators (affecting women) on the global prevalence of early childhood caries (ECC) in 3–5 year old children. Methods Data on global ECC prevalence were obtained from a prior...
Abstract Background Mock-up based approach allows the preview of the aesthetic rehabilitation, however, it is crucial that the mock-up does not differ from the expected aesthetic outcomes. With CAD-CAM technologies, it is possible to directly create mock-ups from virtual planned smile project, with greater accuracy and efficiency compared to the conventional moulded mock-ups. In this study, we investigated the trueness of mock-ups...
Mark above section as read
The incidence of synovial sarcoma is 1.548 per 1,000,000. Synovial sarcoma localized to the palmar surface should, therefore, be considered extremely rare. This report documents a 34-year-old male with a right hand mass that had been present for a few years, continuing to grow in size. The mass was located at the palm and extended from the mid-third metacarpal to involve all digits except the thumb. The mass was determined to be monophasic synovial sarcoma on histopathologic exam. Fluorescence in...
Mark above section as read
The MET proto-oncogene encodes a receptor tyrosine kinase, and binding to its ligand (hepatocyte growth factor [HGF]) induces downstream signaling through the RAS–RAF and phosphoinositide 3-kinase (PI3K) pathways. Aberrant MET signaling drives tumor growth through increased cell proliferation,…
Mark above section as read
Sit-to-stand and stand-to-sit transitions are frequent daily functional tasks indicative of muscle power and balance performance. Monitoring these postural transitions with inertial sensors provides an objecti...
Promising studies have shown that the gait symmetry of individuals with hemiparesis due to brain lesions, such as stroke, can improve through motor adaptation protocols forcing patients to use their affected l...
Mark above section as read
Publication date: Available online 5 June 2020Source: CortexAuthor(s): Elizabeth U. Long, Nathan E. Wheeler, William A. Cunningham
Publication date: Available online 4 June 2020Source: CortexAuthor(s): Noga Cohen, Reout Arbel
Publication date: Available online 4 June 2020Source: CortexAuthor(s): Karin Heidlmayr, Kirsten Weber, Atsuko Takashima, Peter Hagoort
Mark above section as read
34 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Surg Neurol Int"[jour] These pubmed results were generated on 2020/06/05PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Jun 05, 2020 19:08
Mark above section as read
Publication date: August 2020Source: Brain and Language, Volume 207Author(s): Jeffrey P. Johnson, Erin L. Meier, Yue Pan, Swathi Kiran
Mark above section as read
Related ArticlesMerkel cells of human oral mucosa express the pluripotent stem cell transcription factor Sox2. Histol Histopathol. 2020 May 04;:18231 Authors: García-Caballero L, Caneiro J, Gándara M, González-Ortega N, Cepeda-Emiliani A, Gude F, Collado M, Beiras A, Gallego R Abstract Merkel cells are neuroendocrine cells associated to a neural sensitive ending and localized primarily in the epidermis, although they are also found in oral mucosa. Sox2...
Fri Jun 05, 2020 18:51
Mark above section as read
Publication date: May–June 2020Source: Journal of Communication Disorders, Volume 85Author(s):
Mark above section as read
Publication date: Available online 4 June 2020Source: Brain Research BulletinAuthor(s): Jing Li, Longze Sha, Qi Xu
Mark above section as read
Related ArticlesCardiac Resynchronization Therapy for Improving Non-Uniform Thickening of Left Ventricular Wall: Assessment by Quantitative Gated Myocardial Perfusion SPECT. Tohoku J Exp Med. 2020;251(2):69-79 Authors: Wakayama Y, Nakano M, Fukuda K, Kumagai K, Sugai Y, Hirose M, Yamaguchi N, Kondo M, Kaneta T, Fukuda H, Kagaya Y, Shimokawa H Abstract Cardiac resynchronization therapy (CRT) improves cardiac dyssynchrony in heart failure patients with...
Mark above section as read
Publication date: Available online 4 June 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Marisa A. Kollmeier, Sean McBride, Melissa Varghese, Dylan Debonis, Zhigang Zhang, Gilad Cohen, Antonio L. Damato, Borys Mychalczak, Richard Gewanter, Michael J. Zelefsky
Mark above section as read
Abstract Human beings talk to themselves; sometimes out-loud, other times in inner speech. In this paper, I present a resolution to the following dilemma that arises from self-talk. If self-talk exists then either, (i) we know what we are going to say and self-talk serves no communicative purpose, and must serve some other purpose, or (ii) we don’t know what we are going to say, and self-talk does serve a communicative purpose, namely, it is an instance of us communicating with...
Mark above section as read
Vancomycin resistant enterococci (VRE) are of significant public health concern. The identification of VRE in livestock and food has increased. The objective of this study was to determine if the transferrable...
Malocclusion features differ across various populations and ethnicities. At this time, no data are available regarding the dentofacial differences between Syrian and European adolescents with Class II division...
Malaria is an infectious disease that annually presents around 200,000 cases in Brazil. The availability of data on malaria is crucial for enabling and supporting studies that can promote actions to prevent it...
Ligation-Mediated Amplification (LMA) is a versatile biochemical tool for amplifying selected DNA sequences. LMA has increased in popularity due to its integration within chromosome conformation capture (5C) a...
Mark above section as read
Condition: Nasopharyngeal CarcinomaIntervention: Device: transoral flexible endoscope with magnifying narrow band imagingSponsor: Chinese University of Hong KongNot yet recruiting
Interest of Virtual Reality to Prevent Cancer Patient Anxiety Before Chemotherapy or an Invasive Act
Conditions: Anxiety; Chemotherapy Effect; Breast Cancer; Head Cancer NeckIntervention: Behavioral: Virtual reality exposureSponsor: Hospices Civils de LyonNot yet recruiting
Mark above section as read
Related ArticlesSynchronous correction in secondary cleft deformities: a prospective cohort study. Minerva Stomatol. 2020 Jun 02;: Authors: Pendem S, Vb KK Abstract BACKGROUND: Patients with cleft lip and palate deformities undergo multiple surgical procedures from infancy till adolescence. We hypothesized that combining these surgical procedures might offer a better quality of life without compromising on surgical outcomes. SUBJECTS & METHODS:...
Mark above section as read
Antonio MonteroEn los años setenta del pasado siglo, el optimismo respecto a la victoria sobre los microorganismos patógenos y las enfermedades infecciosas que provocaban era tal, y tan generalizado, que el Presidente de EEUU, Richard Nixon, en representación, podría decirse, del sentir general del momento, anunció que había llegado el momento de declararle la guerra al cáncer. Se daban por sentadas dos premisas, que el tiempo ha demostrado que eran erróneas:1.- Las enfermedades infecciosas estaban...
Mark above section as read
Publication date: Available online 4 June 2020Source: Archives of Physical Medicine and RehabilitationAuthor(s): Sandro Iannaccone, Paola Castellazzi, Andrea Tettamanti, Elise Houdayer, Luigia Brugliera, Francesco de Blasio, Paolo Cimino, Marco Ripa, Carlo Meloni, Federica Alemanno, Paolo Scarpellini
Mark above section as read
Related ArticlesModulation of Kinases by Small Molecules for Therapeutic Management of Various Diseases - Part I. Curr Top Med Chem. 2020;20(12):1057-1058 Authors: Bharate SB PMID: 32495727 [PubMed - in process]
Related ArticlesBiological Functions of Polymers and Metal Composites. Curr Top Med Chem. 2020;20(11):913-914 Authors: Kumar B, Manuja A PMID: 32495726 [PubMed - in process]
Related ArticlesArtificial Intelligence Based Design of Polymers and Metal Composites: A Perspective. Curr Top Med Chem. 2020;20(11):911-912 Authors: Manuja A, Manuja M PMID: 32495725 [PubMed - in process]
Related ArticlesLearning the Edit Costs of the Graph Edit Distance Applied to Ligand-Based Virtual Screening. Curr Top Med Chem. 2020 Jun 03;: Authors: Garcia-Hernandez C, Fernández A, Serratosa F Abstract BACKGROUND: Graph edit distance is a methodology used to solve error-tolerant graph matching. This methodology estimates a distance between two graphs by determining the minimum number of modifications required to transform one graph into the other....
Related ArticlesDeveloping a Multi-target Model to Predict the Activity of Monoamine Oxidase A and B Drugs. Curr Top Med Chem. 2020 Jun 03;: Authors: Concu R, González-Durruthy M, Cordeiro MNDS Abstract INTRODUCTION: Monoamine oxidase inhibitors (MAOIs) are compounds largely used in the treatment of the Parkinson's disease (PD), Alzheimer's disease and other neuropsychiatric disorders since are closely related to the MAO enzymes activity. The two isoforms...
Related ArticlesExploring the Potential of Neuroproteomics in Alzheimer's Disease. Curr Top Med Chem. 2020 Jun 03;: Authors: Uddin MS, Kabir MT, Jakaria M, Sobarzo-Sánchez E, Barreto GE, Perveen A, Hafeez A, Bin-Jumah MN, Abdel-Daim MM, Ashraf GM Abstract Alzheimer's disease (AD) is a progressive brain amyloidosis that damages brain regions associated with memory, thinking, behavioral and social skills. Neuropathologically AD is characterized by intraneuronal...
Related ArticlesHeart rate variability based prediction of personalized drug therapeutic response: the present status and the perspectives. Curr Top Med Chem. 2020 Jun 02;: Authors: Pei Z, Shi M, Guo J, Shen B Abstract Heart rate variability (HRV) signals are reported associated with the personalized drug response in many diseases such as major depressive disorder, epilepsy, chronic pain, hypertension, etc. But the relationships between HRV signals and...
Related ArticlesAntiproliferative activity of 8-methoxy ciprofloxacin-hydrozone/acylhydrazone scaffolds. Curr Top Med Chem. 2020 Jun 02;: Authors: Wang LP, Xu Z, Deng GY, Xu SL Abstract AIMS: A series of 8-methoxy ciprofloxacin- hydrazone/acylhydrazone hybrids were evaluated for their activity against a panel of cancer cell lines including HepG2 liver cancer cells, MCF-7, doxorubicin-resistant MCF-7 (MCF-7/DOX) breast cancer cells, DU-145 and multidrug-resistant...
Computational evaluation and in vitro validation of new Epidermal Growth Factor Receptor inhibitors.
Related ArticlesComputational evaluation and in vitro validation of new Epidermal Growth Factor Receptor inhibitors. Curr Top Med Chem. 2020 Jun 03;: Authors: Gómez-Ganau S, Castillo J, Cervantes A, de Julián Ortiz JV, Gozalbes R Abstract The epidermal growth factor receptor (EGFR) is a transmembrane protein that acts as a receptor of extracellular protein ligands of the epidermal growth factor (EGF/ErbB) family. It has been shown that EGFR is overexpressed...
Mark above section as read
Related ArticlesWhat place does molecular topology have in today's drug discovery? Expert Opin Drug Discov. 2020 Jun 04;:1-12 Authors: Zanni R, Galvez-Llompart M, Garcia-Domenech R, Galvez J Abstract INTRODUCTION: Most methods in molecular and drug design are currently based on physicochemical descriptors. However, molecular topology, which relies on topological descriptors, has also shown value for molecular design even if it does not take into account...
Mark above section as read
Publication date: Available online 5 June 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Nathalie Kerfant, Gaëlle Albacete, Anthony Guernec, Manon Inizan, Amerand Aline, Weiguo Hu, Michael Theron, Karine Pichavant-Rafini
Mark above section as read
Gastroesophageal Reflux Disease: A Cause for Eustachian Tube Dysfunction in Obstructive Sleep Apnea.
Related ArticlesGastroesophageal Reflux Disease: A Cause for Eustachian Tube Dysfunction in Obstructive Sleep Apnea. Ear Nose Throat J. 2020 Jun 04;:145561320931219 Authors: Yan S, Wei Y, Zhan X, Yao L, Li X, Fang F, Xu J Abstract OBJECTIVES: To explore the effect of gastroesophageal reflux disease (GERD) on Eustachian tube function in patients with obstructive sleep apnea (OSA). METHODS: This was a cross-sectional study. The patients were...
Related ArticlesEndoscopic Ossiculoplasty for the Management of Isolated Congenital Ossicular Chain Malformation: Surgical Results in 16 Ears. Ear Nose Throat J. 2020 Jun 04;:145561320931218 Authors: Zhang C, Mi J, Long D, Deng Y, Sun Q, Liu Z Abstract OBJECTIVE: The aim of this study is to describe the clinical characteristics and intraoperative findings and further evaluate the efficacy of endoscopic ossiculoplasty for the management of isolated...
Related ArticlesAnatomical Variations in Recurrent Laryngeal Nerves in Thyroid Surgery. Ear Nose Throat J. 2020 Jun 04;:145561320927565 Authors: Yin C, Song B, Wang X Abstract OBJECTIVE: To study terminal bifurcation of recurrent laryngeal nerves (RLNs) with original direction to larynx entry and to decrease the risk of vocal cord paralysis in thyroid patients. METHODS: The RLNs of 294 patients (482 sides) were dissected according to the...
Mark above section as read
Publication date: Available online 4 June 2020Source: Practical Radiation OncologyAuthor(s): Stanley I. Gutiontov
Mark above section as read
Related ArticlesA modular high-density μECoG system on macaque vlPFC for auditory cognitive decoding. J Neural Eng. 2020 Jun 04;: Authors: Chiang CH, Lee J, Wang C, Williams AJ, Lucas TH, Cohen YE, Viventi J Abstract OBJECTIVE: A fundamental goal of the auditory system is to parse the auditory environment into distinct perceptual representations. Auditory perception is mediated by the ventral auditory pathway, which includes the ventrolateral prefrontal...
Related ArticlesEnhancing gesture decoding performance using signals from posterior parietal cortex: a stereo-electroencephalograhy (SEEG) study. J Neural Eng. 2020 Jun 04;: Authors: Wang M, Li G, Jiang S, Wei Z, Hu J, Chen L, Zhang D Abstract OBJECTIVE: Hand movement is a crucial function for humans' daily life. Developing brain-machine interface (BMI) to control a robotic hand by brain signals would help the severely paralyzed people partially regain...
Mark above section as read
Immunostaining of melanosomes (red; NKI/beteb) in a coculture of human melanocytes and keratinocytes
Mark above section as read
Abstract Purpose of Review The goal of this manuscript was to review the growing body of evidence examining the relationship between integrase strand inhibitors (INSTIs) and weight gain in treatment-naïve and treatment-experienced populations of people living with HIV. INSTIs have proven to be efficacious in virologic suppression in combination with other antiretrovirals (ARVs); however, recent data has demonstrated a potential...
Abstract Abstract The high efficacy of new antiretroviral regimens has deeply improved survival of patients living with HIV (PLWH), and currently as the population ages, the focus has shifted to comorbidities especially metabolic disorders which includes nonalcoholic fatty liver disease (NAFLD). Recent Findings Metabolic syndrome is often...
Abstract Purpose of Review Tuberculosis is the number one infectious killer of people with HIV worldwide, but it can be both prevented and treated. Prevention of tuberculosis by screening for and treating latent tuberculosis infection (LTBI), along with the initiation of antiretroviral therapy (ART), is the key component of HIV care. Recent Findings ...
Mark above section as read
Related ArticlesEvaluation of the Diaphragm Muscle Remodeling, Inflammation, Oxidative Stress and Vascularization in Smokers: An Autopsy Study. Cell Physiol Biochem. 2020 Jun 05;54(4):567-576 Authors: Nucci RAB, Maifrino LBM, Busse AL, de Souza RR, Pasqualucci CA, Anaruma CA, Leite REP, Rodriguez RD, Suemoto CK, Jacob-Filho W Abstract BACKGROUND/AIMS: Cigarette smoking is a key factor in systemic inflammation and oxidative stress, and it has also been...
Mark above section as read
Related ArticlesThe Dose Dependent Effects of Ruxolitinib on the Invasion and Tumorigenesis in Gliomas Cells via Inhibition of Interferon Gamma-Depended JAK/STAT Signaling Pathway. J Korean Neurosurg Soc. 2020 Jun 04;: Authors: Delen E, Doğanlar O Abstract Objective: Glioblastoma multiforme (GBM) is the most aggressive for of brain tumor and treatment often fails due to the invasion of tumor cells into neighboring healthy brain tissues. Activation of...
Related ArticlesArachnoid Plasty to Prevent and Reduce Chronic Subdural Hematoma after Clipping Surgery for Unruptured Intracranial Aneurysm : A Meta-Analysis. J Korean Neurosurg Soc. 2020 Jun 04;: Authors: Jang KM, Choi HH, Nam TK, Park YS, Kwon JT Abstract Objective: Recent studies have reported that arachnoid plasty (ARP) using gelatin sponges with fibrin glue reduced the occurrence of chronic subdural hematoma (CSDH) following clipping surgery for...
Related ArticlesVentriculoperitoneal Shunt without Hair Shaving Using Absorbable Suture Materials. J Korean Neurosurg Soc. 2020 Jun 04;: Authors: Lee YH, Kwon YS, Cho JM Abstract Objective: Infection is one of most devastating complications in ventriculoperitoneal (VP) shunt surgery. Preoperative hair removal has traditionally been performed to reduce infectious complications. We performed VP shunt surgeries and evaluated the prevalence of infection...
Mark above section as read
Publication date: July 2020Source: Journal of Phonetics, Volume 81Author(s): Margarethe McDonald, Margarita Kaushanskaya
Acoustic cues in production and perception of the four-way stop laryngeal contrast in Hindi and Urdu
Publication date: July 2020Source: Journal of Phonetics, Volume 81Author(s): Jessamyn Schertz, Sarah Khan
Mark above section as read
Mark above section as read
The authors compared the morphological features of the Eustachian tube (ET) between patients with cleft lip and palate (CL/P) and normal controls using cone-beam computed tomography (CBCT). CBCT images of 51 CL/P patients (28 males and 23 females, mean age: 18.5 ± 8.0 years) and a control group of 52 patients (22 males and 30 females, mean age: 25.23 ± 10.65 years) were retrospectively evaluated. The Eustachian tube angle (ETA), Eustachian tube length (EL), and auditory tube angle (ATA) were measured...
No abstract available
Radiographic Predictors of FACE-Q Outcomes Following Non-Operative Orbital Floor Fracture Management
Background: Orbital floor fractures are common injuries treated by multiple surgical subspecialties. Controversy exists regarding the operative indications. This study sought to correlate radiographic characteristics of orbital floor fractures with validated patient reported outcome measures following non-operative management. Materials and Methods: Patients who underwent non-operative management of an orbital floor fracture at Yale New Haven Hospital from 2013 to 2018 were queried retrospectively....
No abstract available
Introduction: Microvascular free tissue transfer has revolutionized the management of complex composite head and neck defects. Aim: To evaluate the functional and aesthetic outcomes in the primary reconstruction of post-excisional near total hemifacial defects with the chimeric anterolateral thigh flaps (cALT). Materials and methods: The author as a prelude to this clinical study has done a cadaveric study on the quadriceps artery angiosome. In this retrospective cohort study, data are...
Three-dimensional stereophotogrammetry is not much used in assessing facial palsy and a comprehensive understanding of sources of variation in these measurements is lacking. The present study assessed intra- and interobserver reliability of a novel three-dimensional stereophotogrammetry measurement of facial asymmetry and examined sources of variation in these outcomes. Three photographs (rest, closed mouth smile, and maximum smile) were made of 60 participants, 30 facial palsy patients and 30 control...
Human amniotic membrane (HAM) has recently been used as an interpositional material to prevent ankylosis or primary re-ankylosis after temporomandibular joint (TMJ) arthroplasty. Here, the authors describe an unusual case of a 32-year-old woman who presented with a noninflammatory degenerative osteoarthritis of the TMJ in which a HAM was placed following a high condylar arthroplasty and discectomy and show the clinicoradiological results. The procedure resulted in total pain relief and significant...
Machine learning (ML) revolves around the concept of using experience to teach computer-based programs to reliably perform specific tasks. Healthcare setting is an ideal environment for adaptation of ML applications given the multiple specific tasks that could be allocated to computer programs to perform. There have been several scoping reviews published in literature looking at the general acceptance and adaptability of surgical specialities to ML applications, but very few focusing on the application...
Mandibular distraction osteogenesis (MDO) is a fairly common procedure in specialized craniofacial surgery centers. The MDO is a minimally invasive technique that is able to generate new bone in patients with a severe hypoplastic ascending ramus, while also expanding the overlying soft tissues; therefore, it has become the treatment of choice for the surgical correction of mandibular hypoplasias. One of the most common postoperative complications involves misplacement of the distractor and/or corticotomy,...
Background: The best methods to assess surgical knowledge are still debated. The authors used a non-multiple-choice test as a pre- and post-conference assessment to measure residents’ knowledge gains with comparison to a standard summative assessment tool. Methods: At one didactic conference, plastic surgery residents at a single institution were given a pre-test of drawing and labeling structures in the extensor mechanism of the finger and within the carpal tunnel. The quiz was followed...
The purpose of this retrospective study was to assess the genetic and phenotypic features of patients with craniofrontonasal syndrome (CFNS), and the implications of the condition for multidisciplinary management. The subjects were 25 female patients with a mutation of EFNB1, who presented to the Oxford Craniofacial Unit during a 38-year period. Medical records were reviewed for genetic and phenotypic information. Mean duration of follow-up was 12.6 years (range 0–30.7 years). This study examines...
Cleidocranial dysplasia (CCD) is a rare autosomal dominant disorder caused by mutations in the Runx2 gene. The CCD is characterized by frontal bossing, a patent anterior fontanelle, presence of Wormian bones, midface hypoplasia, multiple dental abnormalities, clavicular hypoplasia or aplasia, skeletal abnormalities, and short stature. The aims of this study are to report the phenotypic manifestations of all patients who presented with CCD and to review the multidisciplinary management of these patients....
Lower lip cancer is typically treated with surgical excision, and this frequently results in a large defect and severe aesthetic problems. Local flap reconstruction is suitable for restoring appearance and function, and it causes less surgical stress than a vascularized free flap. The Fusuma sliding flap is a local flap technique introduced by Kasai et al in 2008. Here, the authors report their use of this method for lip reconstruction in a 94-year-old Japanese female after the removal of a cancerous...
Introduction: The aim of this study was to assess the efficacy of using bone morphogenetic protein-2 with hydroxyapatite granules (BMP-2/hydroxyapatite) during augmentation of maxillary sinus floor, with respect to changes in volume, relative to conventional bone graft materials. Method and materials: Twenty of 25 patients in the BMP-2/hydroxyapatite group, and 16 of 33 patients in the conventional materials group met the criteria for inclusion in this study. Computed tomography scans were...
Applications of Computer-Aided Design/Manufacturing Technology in Treatment of Hemifacial Microsomia
Computer-aided surgery has been widely used in treatment of hemifacial microsomia and matured in recent decades. These techniques include the computer-aided design, virtual surgical planning, modeling surgery, rapid prototyping techniques, intraoperative navigation and so on. The purpose of this article is to summarize the current application of computer-aided design/computer-aided manufacturing technology in the treatment for hemifacial microsomia during the last 5 years, as well as the views and...
Background: Free ileocolon flap is a reliable technique allowing simultaneous restoration of swallowing and speech. The aim is to report our 6-year experience in a single center. Methods: Thirty-seven patients treated between 2010 and 2015 were included in the study. Swallowing and speech function were evaluated in 27 patients with a 7-point and 5-point Likert scale, respectively. Moreover, 12 of them consented to voice spectrum analysis (VSA). Results: Complications noted were: aspiration...
No abstract available
Introduction: Adenoidectomy is one of the most common surgical procedures performed in children in otorhinolaryngology practice. This study aims to compare the conventional curettage adenoidectomy (CCA) and the endoscope-assisted coblation adenoidectomy (EACA) in terms of the postoperative Eustachian tube function and the surgical outcomes. Methods: A prospective, randomized, controlled study was carried out at a tertiary referral center and private hospital. Seventy-two adenoid hypertrophy...
Introduction: Panfacial fracture represent a challenge for maxillofacial surgeons due to paucity of useful landmark and stable bone that can be used for fixation. Nowadays, with the availability of rigid and semi rigid fixations, understanding of the importance of the facial buttresses, bone grafting, and early intervention, the functional and cosmetic outcomes showed a significant improvement. Many treatment sequences exist in the literature including top to bottom, bottom to top, lateral to...
Background: Both open cranial vault remodeling (CVR) and endoscopic suturectomy are effective in treating the anatomical deformity of craniosynostosis. While parents are increasingly knowledgeable about these 2 treatment options, information regarding the perioperative outcomes remains qualitative. This makes preoperative counseling regarding surgical choices difficult. The purpose of this study was to evaluate the outcomes in patients with craniosynostosis who underwent traditional CVR versus...
External jugular vein is formed by joining of posterior division of retromandibular vein and posterior auricular vein and common facial vein drain into internal jugular vein. Variations are not uncommon and these are more often observed in veins than in arteries. Aim of the study is to report the prevalence of unique variation of formation of external jugular vein. Head and neck of 6 cadavers (12 sides) fixed in 10% formalin were dissected in the department of anatomy AIIMS Rishikesh for the...
Purpose: To assess maxillary occlusal plane correction in patients with hemifacial microsomia (HFM) after vertical vector mandibular distraction osteogenesis (vMDO) without orthodontic appliances. Methods: A retrospective study was performed on consecutive patients with HFM and Kaban-Pruzansky type-II mandibular deformities who underwent unilateral vMDO by a single surgeon over an 18-month period. Patients with 12-months minimum clinical follow-up and postero-anterior (PA) cephalograms taken...
Background: Cephalohematoma is collection of blood between skull and periosteum that is confined by cranial sutures. Cephalohematomas usually resorb spontaneously within the first month of life; however, if it fails to resolve, ossified cephalohematoma may form. Methods: Clinical archiving system and picture archiving and communication system were retrospectively reviewed for cases of birth-related cephalohematoma. Cases of ossified cephalohematomas identified on imaging were retrieved from...
Introduction: Digital simulators are potential solutions to challenges facing surgical education. The authors sought to evaluate the reach and utilization of a freely-accessible craniofacial surgery digital educational simulator. More importantly, we compare usage patterns between web-based and mobile-based platforms. Methods: A 3-way collaboration between academic, non-profit (myFace, New York, NY), and biotechnology (Biodigital, New York, NY) stakeholders in 2015 produced the Craniofacial...
Synovial cell sarcomas are malignant tumors originating from pluripotent mesenchymal stem cells, unlike its name. It is a common tumor in the periarticular area, accounting for 8% of all soft tissue sarcomas. Head and neck are among the rarest areas of this tumor. Synovial sarcomas of the head and neck are more aggressive than those seen in other regions and are associated with remarkable mortality and morbidity. Treatment of synovial sarcomas of the head and neck is usually extensive local excision...
Resorbable and titanium systems have been used in maxillary fixation. The aim of this review was to evaluate stability and morbidity of Le Fort I osteotomy by comparing both systems. It was performed in 11 databases, and reported according to preferred reporting items for systematic reviews and meta-analysis. Randomized and nonrandomized clinical trials, and retrospective comparative studies with patients who underwent nonsegmented Le Fort I osteotomy were included. Eleven articles were selected,...
Periorbital emphysema is a well-known but very rare complication after rhinoplasty. Here, we present a case of periorbital emphysema presenting with diplopia and eyeball deviation after rhinoplasty. All symptoms disappeared spontaneously within days, without any complications.
A question that remains unanswered is at what level of surgical correction does the public perceive a head shape to be “normal” or “acceptable?” For most cases of non-syndromic asymptomatic craniosynostosis, the parents desire for surgical correction is to improve the cosmetic appearance of head shape. At the time of this writing, the intraoperative surgeons’ perspective of what constitutes an acceptable head shape is the target for surgical correction. In introducing an improved objectively cosmetic...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου