Related ArticlesSelective Posterior Callosotomy for Treatment of Epileptic Drop Attacks: Video Documentation of the Surgical Technique: 2-Dimensional Operative Video. Oper Neurosurg (Hagerstown). 2020 Jun 05;: Authors: Marchiori M, Palmini A, Martins WA, Paglioli RS, Frigeri TM, Paglioli E Abstract This is a surgical technique video of selective posterior callosotomy (SPC), a novel surgical procedure to alleviate refractory epileptic drop attacks.1 Departing...
Sat Jun 06, 2020 15:42
Related ArticlesPrediction of the recurrence risk in patients with epilepsy after the withdrawal of antiepileptic drugs. Epilepsy Behav. 2020 Jun 02;110:107156 Authors: Yang W, Zhang X, Long J, Wu Q, Han Y Abstract Many seizure-free patients who consider withdrawing from antiepileptic drugs (AEDs) hope to discontinue treatment to avoid adverse effects. However, withdrawal has certain risks that are difficult to predict. In this study, we performed a...
Sat Jun 06, 2020 15:42
Related ArticlesIntranasal delivery of topiramate nanoemulsion: Pharmacodynamic, pharmacokinetic and brain uptake studies. Int J Pharm. 2020 Jun 02;:119486 Authors: Patel RJ, Parikh RH Abstract Epilepsy is the noncommunicable and chronic central nervous system disorder characterized by frequent, unprovoked seizures, or electrical disturbances in the brain. Topiramate is used as an antiepileptic drug for the treatment of partial onset seizures, generalized...
Sat Jun 06, 2020 15:42
Related ArticlesEffect of vagus nerve stimulation for the treatment of drug-resistant epilepsy: A protocol of systematic review and meta-analysis. Medicine (Baltimore). 2020 Jun 05;99(23):e20315 Authors: Chen P, Hao MM, Zhu J, Yang ZY Abstract BACKGROUND: Drug-resistant epilepsy (DRE) is a very tricky disorder, which greatly affects quality of life in such patients. Relevant studies suggested that vagus nerve stimulation (VNS) has potential benefits...
Sat Jun 06, 2020 15:42
Related ArticlesEvaluation of Risk Factors for Cerebrospinal Leakage in Pediatric Patients With Cerebral Palsy Treated With Intrathecal Baclofen. J Pediatr Orthop. 2020 Jul;40(6):e522-e526 Authors: Imerci A, Rogers KJ, Miller F, Sees JP Abstract BACKGROUND: Insertion of an intrathecal baclofen (ITB) pump can provide significant benefits in patients with cerebral palsy (CP). However, there are little data describing the risk of complications. Specifically,...
Sat Jun 06, 2020 15:42
Related ArticlesIs NIPA1-associated hereditary spastic paraplegia always 'pure'? Further evidence of motor neurone disease and epilepsy as rare manifestations. Neurogenetics. 2020 Jun 05;: Authors: Tanti M, Cairns D, Mirza N, McCann E, Young C Abstract Pathogenic variants in the nonimprinted in Prader-Willi/Angelman syndrome (NIPA1) gene typically present with pure hereditary spastic paraplegia (HSP) but complex cases are described. We present a patient...
Sat Jun 06, 2020 15:42
Related ArticlesElbasvir/grazoprevir is effective and tolerable for the treatment of HCV GT1-infected patients: A real world multicenter observatory study in Taiwan. J Microbiol Immunol Infect. 2020 May 22;: Authors: Cheng PN, Chen CY, Yu ML, Lin CC, Lin CY, Peng CY, Tseng KC, Lo CC, Tseng IH, Liu CJ Abstract BACKGROUND & AIMS: Treatment of hepatitis C virus (HCV) by elbasvir/grazoprevir (EBR/GZR) was found to be efficacious and well tolerated in...
Sat Jun 06, 2020 15:42
Related ArticlesEfficacy of Repetitive Dual-site Paired Associative Transcranial Magnetic Stimulation in the Treatment of Generalized Anxiety Disorder. Brain Stimul. 2020 Jun 01;: Authors: Lin Y, Chen P, Yang K, Zhou Q, Zhan S, Lin H, Li L, Wang L, Wang Y PMID: 32497739 [PubMed - as supplied by publisher]
Fri Jun 05, 2020 16:34
Related ArticlesDrug Repositioning: Antimalarial Activities of GABA Analogs in Mice Infected with Plasmodium berghei. Cent Nerv Syst Agents Med Chem. 2020 Jun 04;: Authors: Ayankunle A, Wakeel O, Kolawole O, Oyekale A, Ojurongbe O, Adeyeba O Abstract BACKGROUND: Drug repositioning is becoming popular due to the development of resistance to almost all the recommended antimalarials. Pregabalin and gabapentin are chemical analogs of gamma-aminobutyric acid...
Fri Jun 05, 2020 16:34
Related ArticlesCharacteristic of COVID-19 infection in pediatric patients: early findings from two Italian Pediatric Research Networks. Eur J Pediatr. 2020 Jun 03;: Authors: Parri N, Magistà AM, Marchetti F, Cantoni B, Arrighini A, Romanengo M, Felici E, Urbino A, Da Dalt L, Verdoni L, Armocida B, Covi B, Mariani I, Giacchero R, Musolino AM, Binotti M, Biban P, Fasoli S, Pilotto C, Nicoloso F, Raggi M, Miorin E, Buonsenso D, Chiossi M, Agostiniani R, Plebani A, Barbieri...
Fri Jun 05, 2020 13:40
Related ArticlesThe effect of seizure on school attendance among children with epilepsy: a follow-up study at the pediatrics neurology clinic, Tikur Anbessa specialized hospital, Addis Ababa, Ethiopia. BMC Pediatr. 2020 Jun 03;20(1):270 Authors: Hassen O, Beyene A Abstract BACKGROUND: Epilepsy is the most common chronic neurological disease seen in Pediatrics Neurology Units in many developing countries. It affects negatively on school attendance and...
Fri Jun 05, 2020 13:40
Related ArticlesHeart rate variability based prediction of personalized drug therapeutic response: the present status and the perspectives. Curr Top Med Chem. 2020 Jun 02;: Authors: Pei Z, Shi M, Guo J, Shen B Abstract Heart rate variability (HRV) signals are reported associated with the personalized drug response in many diseases such as major depressive disorder, epilepsy, chronic pain, hypertension, etc. But the relationships between HRV signals and...
Fri Jun 05, 2020 13:40
Related ArticlesEffect of short-term transcutaneous trigeminal nerve stimulation on EEG activity in drug-resistant epilepsy. J Neurol Sci. 2019 May 15;400:90-96 Authors: Ginatempo F, Fois C, De Carli F, Todesco S, Mercante B, Sechi G, Deriu F Abstract BACKGROUND: Transcutaneous trigeminal nerve stimulation (TNS) has antiepileptic effects in patients with drug-resistant epilepsy (DRE). However, whether and how TNS is able to modulate the electroencephalogram...
Fri Jun 05, 2020 13:40
Related ArticlesSleep surgery in syndromic and neurologically impaired children. Am J Otolaryngol. 2020 May 27;41(4):102566 Authors: Ali NE, Alyono JC, Kumar AR, Cheng H, Koltai PJ Abstract PURPOSE: To examine surgery performed for obstructive sleep apnea (OSA) in children with syndromic or neurologic comorbidities. MATERIAL AND METHODS: Medical records of 375 children with OSA were retrospectively reviewed, including 142 patients with trisomy...
Sun Jun 07, 2020 14:41
Related ArticlesCoblation® intracapsular tonsillectomy in children with recurrent tonsillitis: Initial experience. Int J Pediatr Otorhinolaryngol. 2020 May 16;135:110113 Authors: Varadharajan K, Caton N, Faulkner J, Khemani S Abstract OBJECTIVES: The use of Coblation® intracapsular tonsillectomy for the treatment of sleep disordered breathing (SDB)/obstructive sleep apnoea (OSA) has an increasing evidence base. However, the results for tonsillitis as...
Sun Jun 07, 2020 14:41
Related ArticlesA Wider Approach to Obstructive Sleep Apnea in Primary Health Care. Acta Med Port. 2020 Jun 01;33(6):442 Authors: Baía C, Abreu IR PMID: 32504523 [PubMed - as supplied by publisher]
Sun Jun 07, 2020 14:41
Related Articles[Tonsillectomy and tonsillotomy]. HNO. 2020 Jun 05;: Authors: Windfuhr JP Abstract The number of operations for tonsillectomy have been significantly decreasing for many years in Germany. In children the number of adenotonsillectomies has decreased by two thirds within a decade. This phenomenon is mirrored by a significant increase in the number of annually performed tonsillotomies, a surgical procedure which is preferably performed for...
Sun Jun 07, 2020 14:41
Related ArticlesImpact of nasal resistance on the distribution of apneas and hypopneas in obstructive sleep apnea. Sleep Med. 2020 Apr 17;71:83-88 Authors: Hoel HC, Kvinnesland K, Berg S Abstract BACKGROUND: This study aims to investigate how increased nasal resistance affects respiratory variables in obstructive sleep apnea (OSA). In this setting, to assess how nasal resistance, as measured by 4-phase rhinomanometry, affects the distribution of hypopneas...
Sat Jun 06, 2020 14:58
Related ArticlesBrief digital sleep questionnaire powered by machine learning prediction models identifies common sleep disorders. Sleep Med. 2020 Mar 23;71:66-76 Authors: Schwartz AR, Cohen-Zion M, Pham LV, Gal A, Sowho M, Sgambati FP, Klopfer T, Guzman MA, Hawks EM, Etzioni T, Glasner L, Druckman E, Pillar G Abstract INTRODUCTION: We developed and validated an abbreviated Digital Sleep Questionnaire (DSQ) to identify common societal sleep disturbances...
Sat Jun 06, 2020 14:58
Related ArticlesAssociation of cervical spondylosis with obstructive sleep apnea. Sleep Med. 2020 Apr 03;71:54-58 Authors: Yang TH, Xirasagar S, Cheng YF, Wu CS, Kao YW, Shia BC, Lin HC Abstract OBJECTIVE: The study objective was to evaluate the association between cervical spondylosis (CS) and a subsequent diagnosis of obstructive sleep apnea (OSA) in light of the expected constricting impact of CS-associated cervical spine changes on the pharyngeal...
Sat Jun 06, 2020 14:58
Related ArticlesAcetazolamide for residual apnea and periodic breathing on continuous positive airway pressure therapy. Sleep Med. 2020 Mar 14;71:52-53 Authors: Ni YN, Thomas RJ PMID: 32502849 [PubMed - as supplied by publisher]
Sat Jun 06, 2020 14:58
Related ArticlesLong Term Speech Outcomes Following Midface Advancement in Syndromic Craniosynostosis. J Craniofac Surg. 2020 Jun 02;: Authors: Zimmerman CE, Sun J, Wes AM, Vu GH, Kalmar CL, Humphries LS, Bartlett SP, Cohen MA, Swanson JW, Taylor JA Abstract Midface advancement by distraction osteogenesis (DO) is commonly performed in patients with craniosynostosis for indications including midface hypoplasia, exorbitism, obstructive sleep apnea, class...
Sat Jun 06, 2020 14:58
Related ArticlesCyclic Alternating Pattern Analysis in Periodic Leg Movements in Sleep in Patients With Obstructive Sleep Apnea Syndrome Before and After Positive Airway Pressure Treatment. J Clin Neurophysiol. 2020 May 26;: Authors: Benbir Senel G, Ozcelik EU, Karadeniz D Abstract PURPOSE: Cyclic alternating pattern (CAP) is known to increase in many conditions of sleep disruption and sleep disorders, including obstructive sleep apnea syndrome and periodic...
Sat Jun 06, 2020 14:58
Related ArticlesFree-running circadian breathing rhythms are eliminated by suprachiasmatic nucleus lesion. J Appl Physiol (1985). 2020 Jun 05;: Authors: Purnell BS, Buchanan GF Abstract It is widely agreed that breathing is subject to circadian regulation. Circadian differences in respiratory physiology significantly impact a number of diseases including sleep apnea, asthma, and seizure-induced death. The effect of time-of-day on breathing has been previously...
Sat Jun 06, 2020 14:58
Related ArticlesCan Overnight Portable Pulse Oximetry be used To Stratify Obstructive Sleep Apnea Risk in Infants? A Correlation Analysis. Pediatr Pulmonol. 2020 Jun 05;: Authors: Ehsan Z, He S, Huang G, Hossain MM, Simakajornboon N Abstract INTRODUCTION: There is limited evidence on the accuracy of oximetry in the evaluation of infant obstructive sleep apnea (OSA). We aimed to determine the utility of overnight oximetry to stratify infants at risk for...
Sat Jun 06, 2020 14:58
Related ArticlesThe effects of mandibular advancement appliance therapy on jaw-closing muscle activity during sleep in patients with obstructive sleep apnea: a 3-6 months follow-up. J Clin Sleep Med. 2020 Jun 05;: Authors: Aarab G, Arcache P, Lavigne GJ, Lobbezoo F, Huynh N Abstract STUDY OBJECTIVES: The main aim of this study was to investigate the effects of mandibular advancement appliance (MAA) therapy on jaw-closing muscle activity (JCMA) time-related...
Sat Jun 06, 2020 14:58
Related ArticlesA survey of positive airway pressure therapy preparedness and outcomes following Hurricane Irma in patients with obstructive sleep apnea. J Clin Sleep Med. 2020 Jun 05;: Authors: Kwasnik A, Barletta P, Abreu AR, Castillo C, Brito Y, Chediak AD Abstract None: Obstructive sleep apnea is a frequent sleep related breathing disorder caused by repetitive collapse of the upper airways leading to intermittent hypoxia and sleep disruption. Positive...
Sat Jun 06, 2020 14:58
Related ArticlesPredicting CPAP failure in patients with suspected sleep hypoventilation identified on ambulatory testing. J Clin Sleep Med. 2020 Jun 05;: Authors: Braganza MV, Hanly PJ, Fraser KL, Tsai WH, Pendharkar SR Abstract STUDY OBJECTIVES: Home sleep apnea testing (HSAT) is commonly used to diagnose obstructive sleep apnea (OSA), but its role in identifying patients with suspected hypoventilation or predicting their response to continuous positive...
Sat Jun 06, 2020 14:58
Related ArticlesApproach to the snoring child. Singapore Med J. 2020 Apr;61(4):170-175 Authors: Tan YH, How CH, Chan YH, Teoh OH Abstract Sleep is an important component in a child's growth and development. Snoring is common in children and often perceived as benign, but habitual snoring may be an indication of obstructive sleep apnoea (OSA). OSA can have health, developmental and cognitive consequences. The three common risk factors for paediatric OSA...
Sat Jun 06, 2020 14:58
Related ArticlesResumption of Positive-Pressure Ventilation Devices for Obstructive Sleep Apnea following Transsphenoidal Surgery: An Institutional Experience of a Surgical Cohort. J Neurol Surg B Skull Base. 2020 Jun;81(3):237-243 Authors: Gravbrot N, Jahnke H, White WL, Little AS Abstract Objectives Transsphenoidal surgery creates a skull base defect that may cause postoperative cerebrospinal fluid (CSF) leakage or pneumocephalus. This study reviewed...
Sat Jun 06, 2020 14:58
Related ArticlesA lower X-gate in TASK channels traps inhibitors within the vestibule. Nature. 2020 Apr 29;: Authors: Rödström KEJ, Kiper AK, Zhang W, Rinné S, Pike ACW, Goldstein M, Conrad LJ, Delbeck M, Hahn MG, Meier H, Platzk M, Quigley A, Speedman D, Shrestha L, Mukhopadhyay SMM, Burgess-Brown NA, Tucker SJ, Müller T, Decher N, Carpenter EP Abstract TWIK-related acid-sensitive potassium (TASK) channels-members of the two pore domain potassium (K2P)...
Sat Jun 06, 2020 14:58
Related ArticlesObstructive Sleep Apnea and Circulating Biomarkers of Oxidative Stress: A Cross-Sectional Study. Antioxidants (Basel). 2020 Jun 02;9(6): Authors: Peres BU, Allen AJH, Shah A, Fox N, Laher I, Almeida F, Jen R, Ayas N Abstract Oxidative stress (OS) drives cardiometabolic diseases. Intermittent hypoxia consistently increases oxidative stress markers. Obstructive sleep apnea (OSA) patients experience intermittent hypoxia and an increased...
Sat Jun 06, 2020 14:58
Related ArticlesEvaluation of Therapeutic Positive Airway Pressure as a Hypoglossal Nerve Stimulation Predictor in Patients With Obstructive Sleep Apnea. JAMA Otolaryngol Head Neck Surg. 2020 Jun 04;: Authors: Seay EG, Keenan BT, Schwartz AR, Dedhia RC Abstract Importance: Recent retrospective hypoglossal nerve stimulation (HGNS) outcomes data suggest that patients with low therapeutic positive airway pressure (PAP) levels achieve greater success than...
Fri Jun 05, 2020 14:47
Gastroesophageal Reflux Disease: A Cause for Eustachian Tube Dysfunction in Obstructive Sleep Apnea.
Related ArticlesGastroesophageal Reflux Disease: A Cause for Eustachian Tube Dysfunction in Obstructive Sleep Apnea. Ear Nose Throat J. 2020 Jun 04;:145561320931219 Authors: Yan S, Wei Y, Zhan X, Yao L, Li X, Fang F, Xu J Abstract OBJECTIVES: To explore the effect of gastroesophageal reflux disease (GERD) on Eustachian tube function in patients with obstructive sleep apnea (OSA). METHODS: This was a cross-sectional study. The patients were divided...
Fri Jun 05, 2020 14:47
Related ArticlesIntercostal lung herniation mimicking retroperitoneal bleeding in a patient with obstructive sleep apnea treated with continuous positive pressure ventilation. Pol Arch Intern Med. 2020 Jun 04;: Authors: Koźlik P, Siwiec A, Kosałka-Węgiel J, Łoboda P, Milewski M PMID: 32495609 [PubMed - as supplied by publisher]
Fri Jun 05, 2020 14:47
Related ArticlesA HIF1a-dependent pro-oxidant state disrupts synaptic plasticity and impairs spatial memory in response to intermittent hypoxia. eNeuro. 2020 Jun 03;: Authors: Arias-Cavieres A, Khuu MA, Nwakudu CU, Barnard JE, Dalgin G, Garcia AJ Abstract Sleep apnea causes cognitive deficits and is associated with several neurologic diseases. Intermittent hypoxia (IH) is recognized as a principal mediator of pathophysiology associated with sleep apnea,...
Fri Jun 05, 2020 14:47
Related ArticlesShort-term results of upper airway stimulation in obstructive sleep apnoea patients: the Amsterdam experience. J Laryngol Otol. 2020 Jun 03;:1-6 Authors: Vonk PE, Ravesloot MJL, van Maanen JP, de Vries N Abstract OBJECTIVES: This paper aimed to: retrospectively analyse single-centre results in terms of surgical success, respiratory outcomes and adverse events after short-term follow up in obstructive sleep apnoea patients treated with...
Fri Jun 05, 2020 14:47
Related ArticlesTreatment of superimposed preeclampsia on chronic hypertension in a twin pregnancy with automatic continuous positive airway pressure: a case report. BMC Pulm Med. 2020 Jun 03;20(1):157 Authors: Kim MS, Moon MJ, Lee YH, Chae KY, Ahn EH Abstract BACKGROUND: Obstructive sleep apnoea (OSA) is related with adverse pregnancy outcomes, including preeclampsia. However, there are small studies about treatment of OSA with automatic continuous...
Fri Jun 05, 2020 14:47
Related ArticlesRisk factors for Poor Asthma Control and Impaired Quality of Life in a Caribbean Population. J Asthma. 2020 Jun 04;:1-14 Authors: Sakhamuri S, Rampersad C, Ramsingh C, Ivey MA, Pinto Pereira LM Abstract OBJECTIVE Asthma, a major cause of disability and reduced quality of life, has a high global prevalence and burden of death. Despite the propitious guidelines, a substantial portion of asthmatics reportedly have poorly controlled disease....
Fri Jun 05, 2020 14:47
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