Background: Tinnitus is a prevalent auditory disorder that frequently co-occurs with hearing loss. It is suggested that tinnitus might have negative impact on speech perception. However, studies thus far have not been able to disentangle tinnitus, hearing loss, and speech in noise intelligibility. We therefore investigated whether there is an association between tinnitus and speech understanding in noise, independent of hearing loss. Methods: Of 4,211 participants from the population-based...
Objectives: To examine the effect of aging on electrically evoked compound action potential (eCAP) growth functions and their relationship with speech recognition in noise in cochlear implant (CI) users. Background: Aging typically leads to difficulty understanding speech in background noise. Previous research has explored cognitive and central auditory mechanisms contributing to these age-related changes. However, it is likely that the peripheral auditory system may also play a role. One...
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Publication date: Available online 5 June 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): S. Pondaven-Letourmy, F. Alvin, Y. Boumghit, F. Simon
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Related ArticlesTransperitoneal laparoscopic adrenalectomy for the resection of large size pheochromocytoma: Case report and literature review. Int J Surg Case Rep. 2020 May 23;71:353-359 Authors: Fajardo R, García N, Díaz F Abstract INTRODUCTION: Pheochromocytomas are rare neuroendocrine tumors that form in chromaffin cells of the neural crest during the embryological period. In the overall population, incidence rate is 0.1%; lack of early diagnosis...
Related ArticlesPrimary papilloma of the proximal ureter in a 13-year old boy: A rare case. Int J Surg Case Rep. 2020 May 23;71:349-352 Authors: Rahbar M, Mardanpour K, Rahbar M, Nasiri SJ Abstract INTRODUCTION: Approximately 1 percent of the tumors observed in the upper urinary tract are primary tumors of the ureter. The exact diagnosis is done by a histologic study. Most cases need surgery, which is done by complete resection of the tumoral segment...
Related ArticlesBilio-thorax: an unrecognized complication of liver surgery. Int J Surg Case Rep. 2020 May 14;71:346-348 Authors: Kerawala AA, Jamal A Abstract INTRODUCTION: Although a rare complication, Biliothorax, or chole-thorax as it has been called in literature, is a devastating entity if not recognized early. Various causes have been reported for biliothorax like inflammatory, abdominal trauma, neoplastic, the most frequent being percutaneous...
Related ArticlesBilateral breast implant associated chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL): A case report. Int J Surg Case Rep. 2020 May 29;71:341-345 Authors: Bletsis PP, Janssen LE, Visser O, Offerman SR, Tellier MA, Laterveer L, Houpt P Abstract INTRODUCTION: An estimated 30.000 breast implants are placed in the Netherlands annually. An increasing amount of reports have linked implants to the rare anaplastic large cell lymphoma...
Related ArticlesAndrogen Insensitivity Syndrome: A rare genetic disorder. Int J Surg Case Rep. 2020 Feb 06;: Authors: Fulare S, Deshmukh S, Gupta J Abstract BACKGROUND: Androgen Insensitivity Syndrome (AIS) is a rare X-linked recessive androgen receptor (AR) disorder with 46XY karyotype. Partial AIS affects 5-7 per 1,000,000 genetically male individuals whereas Complete AIS affects 2-5 per 100,000 genetically male individuals. CAIS CAIS is characterized...
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Related ArticlesInternational consensus on terminology to be used in the field of echinococcoses. Parasite. 2020;27:41 Authors: Vuitton DA, McManus DP, Rogan MT, Romig T, Gottstein B, Naidich A, Tuxun T, Wen H, Menezes da Silva A, World Association of Echinococcosis Abstract Echinococcoses require the involvement of specialists from nearly all disciplines; standardization of the terminology used in the field is thus crucial. To harmonize echinococcosis...
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Related ArticlesBiomechanical comparison of unilateral and bilateral pedicle screws fixation for oblique lumbar inter-body fusion surgery - a finite element analysis. World Neurosurg. 2020 Jun 02;: Authors: Fang G, Lin Y, Wu J, Cui W, Zhang S, Guo L, Sang H, Huang W Abstract BACKGROUND: The most common complication of oblique lumbar interbody fusion (OLIF) is endplate fracture/subsidence. The mechanics of endplate fracture in OLIF surgery are still unclear....
Related ArticlesPassability and Impassability of Microcatheters Through the Neuroform Atlas Stent During the Trans-cell Approach: An Experimental Evaluation. World Neurosurg. 2020 Jun 02;: Authors: Hanaoka Y, Koyama JI, Yamazaki D, Ogiwara T, Ito K, Horiuchi T Abstract BACKGROUND: Trans-cell approach for the Neuroform Atlas stent is occasionally unsuccessful as a microcatheter can be stuck in the struts. This study aimed to evaluate the passability and...
Related ArticlesAnterior Spinal Artery Syndrome: A Rare Precedented Reason of Postoperative Plegia After Spinal Deformity Surgery: A Report of Two Cases. World Neurosurg. 2020 Jun 02;: Authors: Bahadır S, Nabi V, Adhikari P, Ayhan S, Acaroglu E Abstract BACKGROUND: Complications in spinal deformity surgery vary from insignificant to severe. Apart from direct mechanical insult, ischemia can also cause spinal cord injury. Ischemic injury may be detected...
Related ArticlesWhat a Year! World Neurosurg. 2019 Dec;132:xxii Authors: Benzel E, Moore C, Collins R PMID: 32498215 [PubMed - in process]
Related ArticlesTraumatic non-missile penetrating transnasal anterior skull-base fracture and brain injury with cerebrospinal fluid leak: intraoperative leak detection and an effective reconstruction procedure for a localized skull base defect especially after COVID-19 outbreak. World Neurosurg. 2020 Jun 01;: Authors: Yoneoka Y, Aizawa N, Nonomura Y, Ogi M, Seki Y, Akiyama K Abstract BACKGROUND: Cerebrospinal fluid leakage in penetrating skull base injury...
Related ArticlesInpatient Hospital Outcomes and its Association with Insurance Type among Pediatric Neurosurgery Trauma Patients. World Neurosurg. 2020 Jun 01;: Authors: Hagerty V, Samuels S, Levene T, Patel D, Levene H, Spader H Abstract OBJECTIVE: The aim of this study was to assess the association of insurance status and inpatient hospital outcomes among a nationally representative population of pediatric trauma neurosurgery patients. METHODS:...
Related ArticlesSpinal cord compression caused by fibroblastic reticular cell tumour (FRCT) originating from thoracic spine. World Neurosurg. 2020 Jun 01;: Authors: Baig Mirza A, Visagan R, Reisz Z, Bodi I, Bell D, Grahovac G Abstract The authors present the first reported case of a fibroblastic reticular cell tumour (FRCT) presenting with spinal cord compression. FRCT are the rarest subset of dendritic cell tumours, a specific group of haematological...
Related ArticlesComplex management of hydrocephalus secondary to choroid plexus hyperplasia. World Neurosurg. 2020 Jun 01;: Authors: Bernstock JD, Tafel I, Segar DJ, Dowd R, Kappel A, Chen J, Aglan O, Montaser A, Gupta S, Johnston B, Judge J, Fehnel K, Stone S, Warf BC Abstract Hyperplasia of the choroid plexus represents a rare cause of communicating hydrocephalus in children. Recent work has come to associate such pathology with genetic abnormalities...
Related ArticlesSegmental T12 vertebral artery injury treated by endovascular coil placement after kyphoplasty for symptomatic spinal angioma. Case report of a minimal invasive solution for a complication of a minimally invasive spine procedure. World Neurosurg. 2020 Jun 01;: Authors: Soriano Sanchez JA, de Zavalía M, Soto García ME, Rodríguez García M, Solís SS, Gaxiola RC, Hernández MG, Flores Soria ER, Israel Romero Rangel JA Abstract A 70-year-old...
Scientific View on Endoscopic Spine Surgery: Can Spinal Endoscopy become a Mainstream Surgical Tool?
Related ArticlesScientific View on Endoscopic Spine Surgery: Can Spinal Endoscopy become a Mainstream Surgical Tool? World Neurosurg. 2020 Jun 01;: Authors: Chung AS, McKnight B, Wang JC Abstract With the health-care environment becoming increasingly patient centric and cost-conscious, interest levels in spinal endoscopy are at an all-time high. Patient demand for the least invasive procedures combined with surgeon desire to maximally shorten the post-operative...
Related ArticlesThree-Dimensional Versus Two-Dimensional Endoscopic Third Ventriculostomy: Surgical Results Of A Preliminary Comparative Study. World Neurosurg. 2020 Jun 01;: Authors: de Notaris M, Corrivetti F, Catapano G Abstract BACKGROUND: Three-dimensional (3-D) endoscopes have been widely used for a large variety of approaches in neurosurgical practice. However, in the last decade 3-D scopes were barely utilized for ventricular surgery. In the...
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Objectives: This review summarizes current evidence on causes and management strategies for delayed pain post-cochlear implantation (CI) surgery, without clinical evidence of inflammation or infection. Methods: The systematic review was undertaken in line with Preferred Reporting Items for Systematic review and Meta-Analysis Protocols 2015 guidelines. A literature search was undertaken, with inclusion of patients who underwent CI and presented with delayed pain (>3 months post-operatively)...
Objectives: To determine the relationship between vestibular migraine (VM) and motion sickness (MoS) susceptibility and their comorbidity in a large student population, and to assess whether experiencing MoS is associated with higher susceptibility for VM. Methods: Surveys including Motion Sickness Susceptibility Questionnaire (MSSQ) and questions assessing migraine-related symptoms as well as family history of motion sickness and migraine headache were distributed to the university...
Objective: The aim of this study is to present our technique of surgical closure in a series of patients suffering from cerebrospinal fluid (CSF) leak due to inner ear malformations. Study Design and Setting: We conducted a retrospective study in our tertiary care academic department of pediatric otolaryngology. Patients: We did include all patients who presented a CSF leak or bacterial meningitis (one episode or recurrent) related to a malformation of the inner ear. Intervention(s):...
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Related ArticlesMineral intake and clinical symptoms in adult patients with Hypophosphatasia. J Clin Endocrinol Metab. 2020 Jun 05;: Authors: Kuehn K, Hahn A, Seefried L Abstract BACKGROUND: Hypophosphatasia (HPP) is a rare inherited metabolic disorder characterized by deficient activity of the Tissue-Nonspecific Alkaline Phosphatase (TNAP) entailing impaired turnover of phosphorus metabolites. Dietary mineral intake is suspected to influence clinical...
Related ArticlesThe Effect of Ethnicity in the Rate of Beta Cell Functional Loss in the First 3 Years After Type 1 Diabetes Diagnosis. J Clin Endocrinol Metab. 2020 Jun 05;: Authors: Tosur M, Cleves MA, Sosenko JM, Libman I, Baidal DA, Balasubramanyam A, Redondo MJ, Type 1 Diabetes TrialNet Study Group Abstract OBJECTIVE: We set forth to compare ethnicities for metabolic and immunological characteristics at the clinical diagnosis of type 1 diabetes (T1D),...
Related ArticlesSerum 25-Hydroxyvitamin D, Albumin, and Mortality among Chinese Older Adults: A Population-based Longitudinal Study. J Clin Endocrinol Metab. 2020 Jun 05;: Authors: Jin X, Xiong S, Ju SY, Zeng Y, Yan LL, Yao Y Abstract CONTEXT: The associations between serum 25-hydroxyvitamin D concentrations [25(OH)D] and all-cause mortality have been inconsistent in existing literatures. One plausible reason is the interaction of intrinsic vitamin D...
Related ArticlesAn intronic HCP5 variant is associated with age of onset and susceptibility to Graves' disease in UK and Polish cohorts. J Clin Endocrinol Metab. 2020 Jun 05;: Authors: Lane LC, Kuś A, Bednarczuk T, Bossowski A, Daroszewski J, Jurecka-Lubieniecka B, Cordell HJ, Pearce SHS, Cheetham T, Mitchell AL Abstract CONTEXT: The genetic background of young onset Graves' disease (GD) remains largely unknown. An intronic variant in HLA complex P5...
Related ArticlesSex Differences in 11-Oxygenated Androgen Patterns across Adulthood. J Clin Endocrinol Metab. 2020 Jun 04;: Authors: Davio A, Woolcock H, Nanba AT, Rege J, O'Day P, Ren J, Zhao L, Ebina H, Auchus R, Rainey WE, Turcu AF Abstract CONTEXT: The gonads are the major source of sex steroids during reproductive ages. The gonadal function declines abruptly in women and gradually in men. The adrenals produce 11-oxygenated androgens (11-oxyandrogens),...
Related ArticlesA Pragmatic Approach to Inpatient Diabetes Management during the COVID-19 Pandemic. J Clin Endocrinol Metab. 2020 Jun 04;: Authors: Korytkowski M, Antinori-Lent K, Drincic A, Hirsch IB, McDonnell ME, Rushakoff R, Muniyappa R Abstract The pandemic of COVID-19 has presented new challenges to hospital personnel providing care for infected patients with diabetes who represent more than 20% of critically ill patients in intensive care units....
Related ArticlesFirst trimester prenatal dexamethasone treatment is associated with alterations in brain structure at adult age. J Clin Endocrinol Metab. 2020 Jun 04;: Authors: Van't Westeinde A, Karlsson L, Nordenström A, Padilla N, Lajic S Abstract CONTEXT: Prenatal treatment of human disease is rare. Dexamethasone (DEX) is used in pregnancies at risk for congenital adrenal hyperplasia (CAH) to prevent virilization in an affected female fetus. The...
Related ArticlesLetter to the Editor: "Effect of Chronic Pancreatitis on Complications and Mortality in DM Patients: A 10-Year Nationwide Cohort Study". J Clin Endocrinol Metab. 2020 Jul 01;105(7): Authors: Liu Y, Chen HL, Li ZS, Wang D, Hu LH PMID: 32497218 [PubMed - as supplied by publisher]
Related ArticlesEffects of proximal and distal enteral glucose infusion on cardiovascular response in health and type 2 diabetes. J Clin Endocrinol Metab. 2020 Jun 04;: Authors: Zhang X, Jones KL, Horowitz M, Rayner CK, Wu T Abstract CONTEXT: Exposure of the small intestine to nutrients frequently leads to marked reductions in blood pressure (BP) in type 2 diabetes (T2DM). It remains unclear whether the region of the gut exposed to nutrients influences...
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Related ArticlesFluoroscopic Swallowing Abnormalities in Dysphagic Patients Following Anterior Cervical Spine Surgery. Ann Otol Rhinol Laryngol. 2020 Jun 05;:3489420929046 Authors: Ian Dhar S, Wegner AM, Rodnoi P, Wuellner JC, Mehdizadeh OB, Shen SC, Nachalon Y, Nativ-Zeltzer N, Belafsky PC, Klineberg EO Abstract OBJECTIVES: To evaluate the precise objective fluoroscopic abnormalities in persons with dysphagia following anterior cervical spine surgery...
Related ArticlesLong-term Outcomes of Clip Coupler Implantation in Patients with Unilateral Congenital Aural Atresia. Ann Otol Rhinol Laryngol. 2020 Jun 05;:3489420924058 Authors: Zhao C, Yang J, Liu Y, Gao M, Chen P, Zhao S Abstract OBJECTIVE: To evaluate the long-term safety and efficacy of the Clip coupler attached to the stapes head in patients with unilateral congenital aural atresia (CAA). METHODS: This single-center retrospective...
In Reference to Reflux Sign Assessment: Statistical Issue on Reliability to Avoid Misinterpretation.
Related ArticlesIn Reference to Reflux Sign Assessment: Statistical Issue on Reliability to Avoid Misinterpretation. Ann Otol Rhinol Laryngol. 2020 Jun 05;:3489420931489 Authors: Lechien JR, Saussez S, Huet K, Harmegnies B PMID: 32500719 [PubMed - as supplied by publisher]
Related ArticlesImpact of Acamprosate on Chronic Tinnitus: A Randomized-Controlled Trial. Ann Otol Rhinol Laryngol. 2020 Jun 05;:3489420930773 Authors: Farhadi M, Salem MM, Asghari A, Daneshi A, Mirsalehi M, Mahmoudian S Abstract OBJECTIVES: Tinnitus is a common and distressing otologic symptom, with various probable pathophysiologic mechanisms, such as an imbalance between excitatory and inhibitory mechanisms. Acamprosate, generally used to treat...
Related ArticlesDo Medical Students Receive Adequate Otolaryngology Training? A Canadian Perspective. Ann Otol Rhinol Laryngol. 2020 Jun 04;:3489420932593 Authors: Rosvall BR, Singer Z, Fung K, Chin CJ Abstract OBJECTIVES: Otolaryngology-head and neck surgery (OHNS) training has been found to be underrepresented in medical school curricula. The study aimed to assess (i) students' clinical OHNS exposure, (ii) their confidence managing OHNS conditions,...
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Related ArticlesCone-beam computed tomography in dentomaxillofacial radiology: a two-decade overview. Dentomaxillofac Radiol. 2020 Jun 05;:20200145 Authors: Gaêta-Araujo H, Alzoubi T, Vasconcelos KF, Orhan K, Pauwels R, Casselman JW, Jacobs R Abstract OBJECTIVE: The aim of this study was to evaluate and summarize features of currently and formerly available cone-beam computed tomography (CBCT) devices from 1996 to 2019. Additionally, a recommendation...
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There is broad consensus that widespread SARS-CoV-2 testing is essential to safely reopening the United States. A big concern has been test availability, but test accuracy may prove a larger long-term problem. While debate has focused on the accuracy of antibody tests, which identify prior…
Fri Jun 05, 2020 03:00
Governments around the world and throughout the United States are beginning to "reopen their economies" in stages. Some have been considering the use of serologic antibody testing to screen for possible immunity and to identify people who could return to the workplace with less severe mitigation…
Fri Jun 05, 2020 03:00
To address the unprecedented challenge posed by the Covid-19 pandemic, much of the world — including an estimated 90% of Americans — was locked down and socially distanced. Large gatherings were prohibited, most schools and nonessential businesses were closed, and people were asked to stay at home…
Fri Jun 05, 2020 03:00
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Related ArticlesA three-dimensional computed tomography angiography study of the anatomy of the accessory middle colic artery and implications for colorectal cancer surgery. Surg Radiol Anat. 2020 Jun 04;: Authors: Yano M, Okazaki S, Kawamura I, Ito S, Nozu S, Ashitomi Y, Suzuki T, Kamio Y, Hachiya O Abstract PURPOSE: In the present study, we focused on the accessory middle colic artery and aimed to increase the safety and curative value of colorectal...
Related ArticlesThe effect of pectus excavatum deformity on lung volume: fact or myth? Surg Radiol Anat. 2020 Jun 03;: Authors: Cebeci H, Kılınçer A, Özlü MY, Öztürk M, Öncel M, Sunam GS Abstract BACKGROUND AND PURPOSE: Most of the previous studies evaluating lung volume of pectus excavatum (PE) patients were based on spirometric measurements. We aimed to calculate lung volume of patients with PE and compare them with lung volume of patients without...
Related ArticlesCorrelation of clinical features with inferior right hepatic vein incidence: a three-dimensional reconstruction-based study. Surg Radiol Anat. 2020 Jun 03;: Authors: Yang Y, Guan T, Si Y, Xing X Abstract PURPOSE: The correlation between right hepatic vein (RHV) diameter and inferior RHV (IRHV) incidence and that between IRHV incidence and other clinical features remain unclear. We investigated factors correlated with IRHV incidence...
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New England Journal of Medicine, Ahead of Print.
Fri Jun 05, 2020 07:01
New England Journal of Medicine, Ahead of Print.
Fri Jun 05, 2020 07:00
New England Journal of Medicine, Ahead of Print.
Fri Jun 05, 2020 07:00
New England Journal of Medicine, Ahead of Print.
Thu Jun 04, 2020 11:00
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Related ArticlesOral intramuscular myxoma: case report and brief review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jun 01;: Authors: Nisi M, Izzetti R, Gabriele M, Pucci A Abstract OBJECTIVE: Myxomas are rare benign mesenchymal soft tissue tumors that seldom affect the head and neck area. The present report describes a rare case of intramuscular myxoma of the oral cavity and briefly reviews the literature regarding the occurrence...
Related ArticlesPatient injury-related alcohol use-underestimated in patients with facial fractures? Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jun 01;:4333 Authors: Hirvikangas R, Bertell J, Marttila E, Löfgren M, Snäll J, Uittamo J Abstract OBJECTIVE: The aim of this study was to highlight the current underestimation of the role of alcohol in facial fracture etiology and patients' daily life. STUDY DESIGN: A prospective cross-sectional...
Related ArticlesA systematic review of secretory carcinoma of the salivary gland: where are we? Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 31;: Authors: Alves LDB, de Melo AC, Farinha TA, de Lima Araujo LH, Thiago LS, Dias FL, Antunes HS, Amaral Eisenberg AL, Santos Thuler LC, Cohen Goldemberg D Abstract OBJECTIVE: The aim of this systematic review was to describe the epidemiology, diagnostic criteria, differential diagnosis, treatment,...
Related ArticlesHealth-related quality of life after oral cancer treatment: 10-year outcomes. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 31;: Authors: Rogers SN, Lowe D Abstract OBJECTIVE: The aim of this study was to report 10-year health-related quality of life (HRQOL) outcomes after treatment of oral squamous cell carcinoma (OSCC). STUDY DESIGN: Cross-sectional HRQOL surveys collated over a 13-year period for patients treated...
Related ArticlesA clinicopathologic study of secretory carcinoma of minor salivary gland: a series of 4 cases and diagnostic considerations. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 31;: Authors: Owosho AA, Tyler D, Summersgill KF Abstract OBJECTIVE: Secretory carcinoma (SC) of salivary gland is a recently described low-grade malignant neoplasm of the salivary gland, characterized by rearrangement of the ETV6 gene. SC of salivary gland...
Related ArticlesEmbolization and sclerotherapy of maxillofacial arteriovenous malformations with the use of fibrin glue combined with pingyangmycin. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 31;: Authors: Yan Z, Wei J, Wu W, Yang X, Sun M, Wang W, Yang X, Yang X, Yang Y Abstract OBJECTIVE: The objectives of this study were to document the results of using fibrin glue (FG) combined with pingyangmycin (PYM) for the embolism and sclerotherapy...
Related ArticlesUndiagnosed and rare diseases: current challenges, perspectives and contribution of oral cavity examination. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 31;: Authors: Martelli DRB, Martelli Júnior H PMID: 32493682 [PubMed - as supplied by publisher]
Related ArticlesImmunohistochemical expression of stem cell markers OCT-4 and SOX-2 in giant cell tumor, central giant cell granuloma, and peripheral giant cell granuloma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 31;: Authors: Bodhankar K, Bansal S, Jashnani K, Desai RS Abstract OBJECTIVES: This study aimed to evaluate and compare the immunohistochemical expression of OCT-4 and SOX-2 and to determine their use in differentiating giant...
Related ArticlesOral and maxillofacial conditions, dietary aspects, and nutritional status of children with congenital Zika syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 31;: Authors: de Oliveira AMM, de Melo EGM, Mendes MLT, Dos Santos Oliveira SJG, Tavares CSS, Vaez AC, de Vasconcelos SJA, Santos HP, Santos VS, Martins-Filho PRS Abstract OBJECTIVE: The aim of this study was to investigate oral and maxillofacial outcomes in children...
Related ArticlesWhich symptoms negatively affect the oral health-related quality of life in patients with osteonecrosis of the jaw? Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May 31;: Authors: Sato T, Kusunoto J, Takeda D, Kishimoto M, Kashin M, Furudoi S, Akashi M Abstract OBJECTIVES: One of the treatment goals for osteonecrotic lesions of the jaw, such as medication-related osteonecrosis of the jaw (MRONJ) or osteoradionecrosis (ORN), is...
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Abstract Purpose of Review The human gut microbiome is involved in a bi-directional communication pathway with the central nervous system (CNS), termed the microbiota–gut–brain axis. The microbiota–gut–brain axis is believed to mediate or modulate various central processes through the vagus nerve. The microbiota–gut–brain axis is involved with the production of microbial metabolites and immune mediators which trigger changes in...
Abstract Purpose of Review Osteoarthritis (OA) is a highly prevalent cause of chronic hip pain, affecting 27% of adults aged over 45 years and 42% of adults aged over 75 years. Though OA has traditionally been described as a disorder of “wear-and-tear,” recent studies have expanded on this understanding to include a possible inflammatory etiology as well, damage to articular cartilage produces debris in the joint that is phagocytosed...
Abstract Purpose of Review The purpose of this review is to provide a comprehensive update of the different known components of the endogenous cannabinoid system and the mechanisms of action, as it applies to analgesia. Recent Findings Following the discovery of the endogenous cannabinoid system in the early 1990s and the subsequent characterization...
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Background: Despite extensive literature on the classification and management of nasal septal deviation (NSD) for preoperative planning, standardized objective measures to evaluate the NSD severity remains challenging. In this study, we quantitatively analyzed NSD to determine the most predictive two-dimensional (2D) computed tomography (CT)-landmark for overall three-dimensional (3D) septal morphology derived from nasal airway segmentation. Methods: A retrospective study was conducted...
As the most prominent portion of the human body, the face embraces a multifaceted responsibility for functionality and survival while contributing to identity and self-image. Inopportunely, due to its distinctive anatomical location, the face as a unit is highly suspectable to trauma, particularly in warfare. As a result, facial injury creates a physical and psychological trauma that needs to be addressed immediately. In the following article, a detailed literature review was conducted to examine...
It is believed that the use of the nasopharyngeal cannula can maintain the patent upper airway in the immediate post-operative period of orthognathic surgery. The present study is a randomized clinical trial with the objective of evaluating the difference in the use of the nasopharyngeal cannula in the post-operative period of orthognathic surgery with respect to permeability and discomfort. The sample was composed of 26 individuals with repaired cleft lip and palate randomly distributed in 2 groups...
Morphological variations of falx cerebri and tentorium cerebelli are extremely rare. The authors report an extremely rare type of combined variation of falx cerebri and dural venous sinuses in the tentorium cerebelli. During the removal of the brain from cranial cavity, it was noted that the anterior part of the falx cerebri had fenestrations and it looked like a mesh. There was no associated variations of medial surface of cerebrum. Further, there were unusual sinuses within the tentorium cerebelli....
On January 8, 2020, a novel coronavirus was officially announced as the causative pathogen of coronavirus disease (COVID-19) by the Chinese Center for Disease Control and Prevention. On February 26, COVID-19 has been recognized in 34 countries, with a total of 80,239 laboratory-confirmed patients and 2700 deaths. Protecting healthcare workers from infectious hazards is paramount to ensuring their safety in delivering health care. In addition, being able to protect healthcare workers,...
The cervicofacial flap is a workhorse flap for reconstruction of moderate to large sized defects of the cheek. Defects that involve the eyelid-cheek junction are often the most challenging of these. While the ideal plane of dissection has been debated, it is our belief that dissection in the sub-superficial musculo-aponeurotic system (SMAS) plane provides better aesthetic and functional outcomes due to enhanced vascularity, fascial support, and additional bulk of the flap itself. The authors present...
Background: Isolated symphyseal or parasymphyseal mandibular fractures can confer significant morbidity in children. However, this mandibular injury pattern has not been well-characterized in children. This study investigated isolated symphyseal/parasymphyseal mandibular fractures in pediatric patients. Methods: This was a 29-year retrospective, longitudinal cohort study of pediatric patients who presented to a single institution with isolated symphyseal/parasymphyseal mandibular fractures....
Translating bone regeneration induced by recombinant human bone morphogenetic proteins from animal models to human patients has proven inexplicably inconsistent. This prompted us to test in 5 pediatric patients, an alternative osteoinductive morphogen, recombinant human transforming growth factor β3 (rhTGF-β3), to reconstruct mandibular defects of such a size to preclude reconstruction with autologous bone. An osteoinductive implant of human demineralized bone matrix (DBM) loaded with 125 μg rhTGF-β3...
Midface advancement by distraction osteogenesis (DO) is commonly performed in patients with craniosynostosis for indications including midface hypoplasia, exorbitism, obstructive sleep apnea, class III malocclusion, and overall aesthetic facial deficiency.1 There is evidence to suggest that maxillary LeFort I advancement increases the risk of velopharyngeal dysfunction in the cleft palate population,2,3 yet few studies have investigated changes in speech following LeFort III or monobloc midface advancement...
Background: A large number of researches related to auricle development have been conducted in different countries, but there were few similar studies in China, especially in Chinese children. This study was designed to investigate the auricular development by measuring normal age- and sex-related dimensions of auricles in Chinese children. Methods: A total of 900 participants were evaluated according to their age and gender. From the landmarks, the dimensions of the and tragus including...
Adult patients’ severe malocclusions, especially the skeletal ones, cannot be exclusively solved by the orthodontic treatment and therefore a combined orthodontic-surgical treatment is necessary. Today, numerous software allows to plane and to visualize the final treatment results simulating the best therapeutic option. This is a retrospective experimental study that aims to analyze the changes in the buccal cortical bone in patients undergoing orthodontics surgeries and to evaluate the correlation...
Nasal septal deviation (NSD) is a common condition in otorhinolaryngology practice. The aim of this study was to investigate the possible relationship between localization and severity of NSD, and related complaints as well as to suggest a simplified assessment method for NSD. Seventy-five patients who complaint nasal obstruction were enrolled this study. The affected nasal cavity was divided into 4 separate sections as follows: antero-superior (AS), antero-inferior (AI), postero-superior (PS), and...
Barbed thread lifting is a widely used method because it is easier to learn, faster, and the lower frequency of complications than the invasive lifting technique. The number of reported cases about complication requiring an invasive procedure is very small, and most cases are limited to minor complications. The authors introduce a chronic, recurrent epidermal inclusion cyst that occurs after Barbed thread lifting. A 61-year-old woman visited the hospital with recurrent inflammation and scar accompanied...
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Related ArticlesUltrasound validation of predictive model for central cervical lymph node metastasis in papillary thyroid cancer on BRAF. Future Oncol. 2020 Jun 05;: Authors: Chen J, Li XL, Zhang YF, Wang D, Wang Q, Zhao CK, Li MX, Wei Q, Ji G, Xu HX Abstract Aim: To compare the value of predictive power of the models for central cervical lymph node metastasis (CLNM) in papillary thyroid carcinomas (PTCs). Patients & methods: 220 PTCs were prospectively...
Related ArticlesImmunotherapy combinations for the treatment of patients with solid tumors. Future Oncol. 2020 Jun 05;: Authors: Bluthgen MV, Basté N, Recondo G Abstract Immune checkpoint inhibitors directed against CTLA-4, PD-1 and PD-L1 have transformed the treatment of patients with cancer. Immunotherapy regimens have evolved from a single agent approach to the combination of immune checkpoint inhibitors like anti CTLA-4 and PD-1, immune checkpoint...
Related ArticlesComprehensive analysis of microenvironment-related genes in lung adenocarcinoma. Future Oncol. 2020 Jun 05;: Authors: Tao Y, Li Y, Liang B Abstract Aim: Understanding the cell types and cell compositions in tumor environment (TME) and the gene changes in lung adenocarcinoma (LUAD) may provide insights on immune profiles and treatment targets for LUAD patients. Materials & methods: The RNA-Seq data from The Cancer Genome Atlas database...
Related ArticlesNanoparticle albumin-bound paclitaxel/liposomal-encapsulated doxorubicin in HER2-negative metastatic breast cancer patients. Future Oncol. 2020 Jun 05;: Authors: Fabi A, Ferretti G, Malaguti P, Gasparro S, Nisticò C, Arpino G, Papaldo P, Russillo M, Catania G, Schettini F, Giannarelli D, Cognetti F Abstract Aim: To investigate the toxicity of nab-paclitaxel (wNP)/nonpegylated liposome-encapsulated doxorubicin (wNPLD) combination in HER2-negative...
Related ArticlesReal-world disease burden and outcomes of brain metastases in EGFR mutation-positive non-small-cell lung cancer. Future Oncol. 2020 Jun 04;: Authors: Nadler E, Espirito JL, Pavilack M, Baidoo B, Fernandes A Abstract Aim: To evaluate the real-world impact of brain metastases (BM) among patients with EGFR mutation-positive (EGFRm) metastatic non-small-cell lung cancer (NSCLC). Materials & methods: This retrospective, observational matched...
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Related ArticlesChallenges faced by patients with morphea in the era of SARS-CoV-2. J Dermatolog Treat. 2020 Jun 05;:1-6 Authors: Shahidi Dadras M, Namazi N, Nikvar M, Abdollahimajd F PMID: 32502370 [PubMed - as supplied by publisher]
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