Antibiotics, Vol. 9, Pages 311: Public Hospital Pharmacists’ Perceptions and Knowledge of Antibiotic Use and Resistance: A Multicenter Survey Antibiotics doi: 10.3390/antibiotics9060311 Authors: Kai Lun Tang Tsyr Fen Teoh Theng Theng Ooi Wei Ping Khor Sook Yee Ong Phin Phin Lim Sarah Abdul Karim Sherene Su Ann Tan Pao Pao Ch’ng Yen Ching Choong Weng Siang Foong Sunitha Ganesan Amer Hayat Khan Long Chiau Ming Antimicrobial Stewardship Program (ASP)...
Antibiotics, Vol. 9, Pages 308: Antimicrobial Resistance Determinants Circulating among Thermophilic Campylobacter Isolates Recovered from Broilers in Ireland Over a One-Year Period Antibiotics doi: 10.3390/antibiotics9060308 Authors: Lynch Lynch Burke Hawkins Buttimer Mc Carthy Egan Whyte Bolton Coffey Lucey Campylobacteriosis is the leading cause of human bacterial gastroenteritis, very often associated with poultry consumption. Thermophilic...
Antibiotics, Vol. 9, Pages 309: Paclitaxel, Imatinib and 5-Fluorouracil Increase the Unbound Fraction of Flucloxacillin In Vitro Antibiotics doi: 10.3390/antibiotics9060309 Authors: Stolte Ali Jänis Gessner El-Najjar Flucloxacillin (FLU), an isoxazolyl penicillin, is widely used for the treatment of different bacterial infections in intensive care units (ICU). Being highly bound to plasma proteins, FLU is prone to drug-drug interactions (DDI) when administered concurrently...
Antibiotics, Vol. 9, Pages 310: A Nationwide Survey of Australian General Practitioners on Antimicrobial Stewardship: Awareness, Uptake, Collaboration with Pharmacists and Improvement Strategies Antibiotics doi: 10.3390/antibiotics9060310 Authors: Saha Kong Thursky Mazza Implementing antimicrobial stewardship (AMS) programs is central to optimise antimicrobial use in primary care. This study aims to assess general practitioners’ (GPs’) awareness of AMS,...
Antibiotics, Vol. 9, Pages 307: Influence of Single Nucleotide Polymorphisms on Rifampin Pharmacokinetics in Tuberculosis Patients Antibiotics doi: 10.3390/antibiotics9060307 Authors: Levin Thomas Sonal Sekhar Miraj Mallayasamy Surulivelrajan Muralidhar Varma Chidananda S. V. Sanju Mahadev Rao Rifampin (RF) is metabolized in the liver into an active metabolite 25-desacetylrifampin and excreted almost equally via biliary and renal routes. Various influx and efflux transporters...
Antibiotics, Vol. 9, Pages 306: HNP-1 and HBD-1 as Biomarkers for the Immune Systems of Elite Basketball Athletes Antibiotics doi: 10.3390/antibiotics9060306 Authors: Raffaela Pero Mariarita Brancaccio Cristina Mennitti Luca Gentile Adelaide Franco Sonia Laneri Margherita G. De Biasi Chiara Pagliuca Roberta Colicchio Paola Salvatore Giovanni D’Alicandro Daniela Terracciano Michele Cennamo Evelina La Civita Antonietta Liotti Cristina Mazzaccara...
Antibiotics, Vol. 9, Pages 305: Bioengineered Nisin Derivative M17Q Has Enhanced Activity against Staphylococcus epidermidis Antibiotics doi: 10.3390/antibiotics9060305 Authors: Ellen Twomey Colin Hill Des Field Maire Begley Staphylococcus epidermidis is frequently implicated in medical device-related infections. As a result of this, novel approaches for control of this opportunistic pathogen are required. We examined the ability of the natural peptide nisin A, produced by Lactococcus...
Antibiotics, Vol. 9, Pages 303: Impact of a Diagnosis-Centered Antibiotic Stewardship on Incident Clostridioides difficile Infections in Older Inpatients: An Observational Study Antibiotics doi: 10.3390/antibiotics9060303 Authors: Putot Astruc Barben Mihai Nuss Bador Putot Dipanda Laborde Vovelle Da Silva Mazen Aho Glélé Manckoundia In 2015, a major increase in incident hospital-onset Clostridioides difficile infections (HO-CDI) in...
Antibiotics, Vol. 9, Pages 304: Phage Therapy as a Novel Strategy in the Treatment of Urinary Tract Infections Caused by E. Coli Antibiotics doi: 10.3390/antibiotics9060304 Authors: Zalewska-Piątek Piątek Urinary tract infections (UTIs) are regarded as one of the most common bacterial infections affecting millions of people, in all age groups, annually in the world. The major causative agent of complicated and uncomplicated UTIs are uropathogenic E. coli strains (UPECs). Huge problems...
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Antioxidants, Vol. 9, Pages 501: Effect of Grafting on the Production, Physico-Chemical Characteristics and Nutritional Quality of Fruit from Pepper Landraces Antioxidants doi: 10.3390/antiox9060501 Authors: Ramón Gisbert-Mullor Costanza Ceccanti Yaiza Gara Padilla Salvador López-Galarza Ángeles Calatayud Giuseppe Conte Lucia Guidi Grafting is a widely utilized agronomical technique to improve yield, disease resistance, and quality of fruit and vegetables. This work...
Antioxidants, Vol. 9, Pages 502: Research Advances in the Use of Bioactive Compounds from Vitis vinifera By-Products in Oral Care Antioxidants doi: 10.3390/antiox9060502 Authors: Bogdan Pop Iurian Benedec Moldovan Oral health is considered an important factor of general health and it contributes to the quality of life. Despite the raising awareness of preventive measures, the prevalence of oral health conditions continues to increase. In this context, a growing interest...
Antioxidants, Vol. 9, Pages 500: Copper Sources for Sod1 Activation Antioxidants doi: 10.3390/antiox9060500 Authors: Stefanie D. Boyd Morgan S. Ullrich Amelie Skopp Duane D. Winkler Winkler Copper ions (i.e., copper) are a critical part of several cellular processes, but tight regulation of copper levels and trafficking are required to keep the cell protected from this highly reactive transition metal. Cu, Zn superoxide dismutase (Sod1) protects the cell from the accumulation...
Antioxidants, Vol. 9, Pages 499: Composition of Royal Jelly (RJ) and Its Anti-Androgenic Effect on Reproductive Parameters in a Polycystic Ovarian Syndrome (PCOS) Animal Model Antioxidants doi: 10.3390/antiox9060499 Authors: Norhamidar Ab Hamid Ainul Bahiyah Abu Bakar Anani Aila Mat Zain Nik Hazlina Nik Hussain Zaidatul Akmal Othman Zaida Zakaria Mahaneem Mohamed Royal jelly (RJ) has been shown to contribute its positive effects upon imbalance in the reproductive system....
Antioxidants, Vol. 9, Pages 498: The Role of Nutri(epi)genomics in Achieving the Body’s Full Potential in Physical Activity Antioxidants doi: 10.3390/antiox9060498 Authors: Irene Petracci Rosita Gabbianelli Laura Bordoni Physical activity represents a powerful tool to achieve optimal health. The overall activation of several molecular pathways is associated with many beneficial effects, mainly converging towards a reduced systemic inflammation. Not surprisingly, regular activity...
Antioxidants, Vol. 9, Pages 496: Influence of Long-Term Fasting on Blood Redox Status in Humans Antioxidants doi: 10.3390/antiox9060496 Authors: Françoise Wilhelmi de Toledo Franziska Grundler Nikolaos Goutzourelas Fotios Tekos Eleni Vassi Robin Mesnage Demetrios Kouretas Fasting is increasingly practiced to improve health and general well-being, as well as for its cytoprotective effects. Changes in blood redox status, linked to the development of a variety of metabolic...
Antioxidants, Vol. 9, Pages 497: Risk Associated with the LEPR rs8179183 GG Genotype in a Female Korean Population with Obesity Antioxidants doi: 10.3390/antiox9060497 Authors: Kyunghye Jang Gurum Shin Hye Jin Yoo Jong Ho Lee Minjoo Kim The difference between metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO) phenotypes might be partly attributable to genetic traits modulating body fat distribution and other obesity-related metabolic traits, specifically...
Antioxidants, Vol. 9, Pages 495: Chemical Composition and Biological Activities of the Nord-West Romanian Wild Bilberry (Vaccinium myrtillus L.) and Lingonberry (Vaccinium vitis-idaea L.) Leaves Antioxidants doi: 10.3390/antiox9060495 Authors: Ștefănescu Călinoiu Ranga Fetea Mocan Vodnar Crișan This study was performed to evaluate and compare the in vitro antioxidant, antimicrobial, and antimutagenic activities, and the polyphenolic content of the Nord-West Romanian...
Antioxidants, Vol. 9, Pages 494: Retinal Nerve Fiber Layer Thickness and Oxidative Stress Parameters in Migraine Patients without Aura: A Pilot Study Antioxidants doi: 10.3390/antiox9060494 Authors: Adriana Elena Bulboacă Ioana C. Stănescu Sorana D. Bolboacă Angelo C. Bulboacă Gyorgy I. Bodizs Cristina A. Nicula Background: Migraine is one of the most common disorders and its pathophysiological mechanisms are still under research, oxidative stress being emphasized as an...
Antioxidants, Vol. 9, Pages 493: Detection of Antioxidant Phytochemicals Isolated from Camellia japonica Seeds Using HPLC and EPR Imaging Antioxidants doi: 10.3390/antiox9060493 Authors: Chalermpong Saenjum Thanawat Pattananandecha Kouichi Nakagawa In this study, we investigated the formation of stable radicals and compounds related to antioxidants in Camellia japonica seeds using high performance liquid chromatography (HPLC) and X-band electron paramagnetic resonance imaging (EPRI)....
Antioxidants, Vol. 9, Pages 492: Cadmium-Induced Oxidative Stress: Focus on the Central Nervous System Antioxidants doi: 10.3390/antiox9060492 Authors: Jacopo J. V. Branca Claudia Fiorillo Donatello Carrino Ferdinando Paternostro Niccolò Taddei Massimo Gulisano Alessandra Pacini Matteo Becatti Cadmium (Cd), a category I human carcinogen, is a well-known widespread environmental pollutant. Chronic Cd exposure affects different organs and tissues, such as the central...
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Atmosphere, Vol. 11, Pages 605: Study on the Accelerated Aging Test Method in the Development of a Self-Cleaning Topcoat for Cool Roofs Atmosphere doi: 10.3390/atmos11060605 Authors: Aoyama Sonoda Takebayashi The heat island phenomenon in urban areas has become a problem in the recent years. One measure to overcome this, which has been attracting attention, is painting the cool roof with a paint that has high solar reflectance. However, the solar reflectance has been reported...
Atmosphere, Vol. 11, Pages 603: Towards Sustainable Neighborhoods in Europe: Mitigating 12 Environmental Impacts by Successively Applying 8 Scenarios Atmosphere doi: 10.3390/atmos11060603 Authors: Kameni Nematchoua Sevin Reiter The purpose of this research is to determine the most impactful and important source of environmental change at the neighborhood level. The study of multiple scenarios allows us to determine the influence of several parameters on the results of the life...
Atmosphere, Vol. 11, Pages 604: Energy Efficiency, Thermal Comfort, and Heritage Conservation in Residential Historic Buildings as Dynamic and Systemic Socio-Cultural Practices Atmosphere doi: 10.3390/atmos11060604 Authors: Kalliopi Fouseki David Newton Krisangella Sofia Murillo Camacho Sohini Nandi Theodora Koukou With buildings being responsible for nearly a quarter of global greenhouse gas emissions, intensive building decarbonization programs are in place worldwide, with...
Atmosphere, Vol. 11, Pages 602: SARIMA Approach to Generating Synthetic Monthly Rainfall in the Sinú River Watershed in Colombia Atmosphere doi: 10.3390/atmos11060602 Authors: Luisa Martínez-Acosta Juan Pablo Medrano-Barboza Álvaro López-Ramos John Freddy Remolina López Álvaro Alberto López-Lambraño Seasonal Auto Regressive Integrative Moving Average models (SARIMA) were developed for monthly rainfall time series. Normality of the rainfall time series was achieved by using...
Atmosphere, Vol. 11, Pages 599: Comparison of Assimilating All-Sky and Clear-Sky Satellite Radiance for Typhoon Chan-Hom and Nangka Forecasts Atmosphere doi: 10.3390/atmos11060599 Authors: Jingnan Wang Lifeng Zhang Jiping Guan Mingyang Zhang The impacts of assimilating all-sky satellite radiance from the Advanced Microwave Scanning Radiometer 2 (AMSR2) on typhoon Chan-hom and Nangka are evaluated over traditional clear-sky radiance assimilation. Results show that more AMSR2...
Atmosphere, Vol. 11, Pages 601: Assimilation of Himawari-8 Rapid-Scan Atmospheric Motion Vectors on Tropical Cyclone in HWRF System Atmosphere doi: 10.3390/atmos11060601 Authors: Sawada Ma Mehra Tallapragada Oyama Shimoji This study investigates the assimilation impact of rapid-scan (RS) atmospheric motion vectors (AMVs) derived from the geostationary satellite Himawari-8 on tropical cyclone (TC) forecasts. Forecast experiments for three TCs in 2016 in the western...
Atmosphere, Vol. 11, Pages 600: Risk Perception on Haze Pollution and Willingness to Pay for Self-Protection and Haze Management in Chiang Mai Province, Northern Thailand Atmosphere doi: 10.3390/atmos11060600 Authors: Sereenonchai Arunrat Kamnoonwatana Air pollution is an important environmental health risk that affects people worldwide, including those in the Chiang Mai Province, Northern Thailand. A questionnaire survey based on accidental sampling to explore risk perception...
Atmosphere, Vol. 11, Pages 598: Exposure and Respiratory Tract Deposition Dose of Equivalent Black Carbon in High Altitudes Atmosphere doi: 10.3390/atmos11060598 Authors: Leizel Madueño Simonas Kecorius Marcos Andrade Alfred Wiedensohler The traffic microenvironment accounts for a significant fraction of the total daily dose of inhaled air pollutants. The adverse effects of air pollution may be intensified in high altitudes (HA) due to increased minute ventilation (MV), which...
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Beverages, Vol. 6, Pages 38: Development of a Spirit Drink Produced with Strawberry Tree (Arbutus unedo L.) Fruit and Honey Beverages doi: 10.3390/beverages6020038 Authors: Ofélia Anjos Sara Canas José Carlos Gonçalves Ilda Caldeira Food safety and diversification of agri-food products are increasingly important. A new spirit drink produced from the arbutus fruit (strawberry tree fruit) and honey was designed, taking advantage of the best features of these two ingredients and...
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Bioengineering, Vol. 7, Pages 54: Andean Sacha Inchi (Plukenetia Volubilis L.) Leaf-Mediated Synthesis of Cu2O Nanoparticles: A Low-Cost Approach Bioengineering doi: 10.3390/bioengineering7020054 Authors: Kumar Smita Debut Cumbal In this work, Andean sacha inchi (Plukenetia volubilis L.) leaves were used to prepare monodispersed cuprous oxide (Cu2O) nanoparticles under heating. Visual color changes and UV-visible spectroscopy of colloidal nanoparticles showed λmax...
Bioengineering, Vol. 7, Pages 53: An Analysis of the Effects of Noisy Electrocardiogram Signal on Heartbeat Detection Performance Bioengineering doi: 10.3390/bioengineering7020053 Authors: Ziti Fariha Mohd Apandi Ryojun Ikeura Soichiro Hayakawa Shigeyoshi Tsutsumi Heartbeat detection for ambulatory cardiac monitoring is more challenging as the level of noise and artefacts induced by daily-life activities are considerably higher than monitoring in a hospital setting. It is valuable...
Bioengineering, Vol. 7, Pages 52: Material-Dependent Formation and Degradation of Bone Matrix—Comparison of Two Cryogels Bioengineering doi: 10.3390/bioengineering7020052 Authors: Weidong Weng Victor Häussling Romina H. Aspera-Werz Fabian Springer Helen Rinderknecht Bianca Braun Markus A. Küper Andreas K. Nussler Sabrina Ehnert Cryogels represent ideal carriers for bone tissue engineering. We recently described the osteogenic potential of cryogels with different...
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Biology, Vol. 9, Pages 120: An Acromegaly Disease Zebrafish Model Reveals Decline in Body Stem Cell Number along with Signs of Premature Aging Biology doi: 10.3390/biology9060120 Authors: Abdalla Elbialy Yoji Igarashi Shuichi Asakawa Shugo Watabe Shigeharu Kinoshita In our previous publication, it was shown that growth hormone (GH) excess in acromegaly affects the cell integrity of somatic cells through increased DNA damage throughout the body and impaired DNA repair pathways....
Biology, Vol. 9, Pages 119: Dietary Supplementation with Omega-6 LC-PUFA-Rich Microalgae Regulates Mucosal Immune Response and Promotes Microbial Diversity in the Zebrafish Gut Biology doi: 10.3390/biology9060119 Authors: Sagar Nayak Ashraf Al Al Ashhab Dina Zilberg Inna Khozin-Goldberg The effect of dietary omega-6 long-chain polyunsaturated fatty acid (LC-PUFA) on host microbiome and gut associated immune function in fish is unexplored. The effect of dietary supplementation...
Biology, Vol. 9, Pages 118: Regional Phenotypic Differences of the Opener Muscle in Procambarus clarkii: Sarcomere Length, Fiber Diameter, and Force Development Biology doi: 10.3390/biology9060118 Authors: Rachel C. Holsinger Robin L. Cooper The opener muscle in the walking legs of the crayfish (Procambarus clarkii) has three distinct phenotypic regions although innervated by only one excitatory motor neuron. These regions (distal, central, and proximal) have varied biochemistry and...
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Biomedicines, Vol. 8, Pages 154: Free Fatty Acid Receptors 2 and 3 as Microbial Metabolite Sensors to Shape Host Health: Pharmacophysiological View Biomedicines doi: 10.3390/biomedicines8060154 Authors: Sidharth P. Mishra Prashantha Karunakar Subhash Taraphder Hariom Yadav The role of the gut microbiome in human health is becoming apparent. The major functional impact of the gut microbiome is transmitted through the microbial metabolites that are produced in the gut and interact...
Biomedicines, Vol. 8, Pages 153: Possible Correlation between Cholinergic System Alterations and Neuro/Inflammation in Multiple Sclerosis Biomedicines doi: 10.3390/biomedicines8060153 Authors: Gatta Mengod Reale Tata Multiple sclerosis (MS) is an autoimmune and demyelinating disease of the central nervous system. Although the etiology of MS is still unknown, both genetic and environmental factors contribute to the pathogenesis of the disease. Acetylcholine participates in...
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Biomimetics, Vol. 5, Pages 27: Metal Oxide Nanoparticles as Biomedical Materials Biomimetics doi: 10.3390/biomimetics5020027 Authors: Maria P. Nikolova Murthy S. Chavali The development of new nanomaterials with high biomedical performance and low toxicity is essential to obtain more efficient therapy and precise diagnostic tools and devices. Recently, scientists often face issues of balancing between positive therapeutic effects of metal oxide nanoparticles and their toxic side effects....
Biomimetics, Vol. 5, Pages 26: Rapidly Exploring Random Tree Algorithm-Based Path Planning for Worm-Like Robot Biomimetics doi: 10.3390/biomimetics5020026 Authors: Yifan Wang Prathamesh Pandit Akhil Kandhari Zehao Liu Kathryn A. Daltorio Inspired by earthworms, worm-like robots use peristaltic waves to locomote. While there has been research on generating and optimizing the peristalsis wave, path planning for such worm-like robots has not been well explored. In this paper,...
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Biomolecules, Vol. 10, Pages 880: The Effect of Escitalopram on Central Serotonergic and Dopaminergic Systems in Patients with Cervical Dystonia, and Its Relationship with Clinical Treatment Effects: A Double-Blind Placebo-Controlled Trial Biomolecules doi: 10.3390/biom10060880 Authors: Evelien Zoons Marina A.J. Tijssen Yasmine E.M. Dreissen Marenka Smit Jan Booij Purpose: The pathophysiology of cervical dystonia (CD) is thought to be related to changes in dopamine and serotonin...
Biomolecules, Vol. 10, Pages 881: Fibrillization of 40-Residue β-Amyloid Peptides in Membrane-Like Environments Leads to Different Fibril Structures and Reduced Molecular Polymorphisms Biomolecules doi: 10.3390/biom10060881 Authors: Qinghui Cheng Zhi-Wen Hu Yuto Tobin-Miyaji Amy E. Perkins Terrence Deak Wei Qiang The molecular-level polymorphism in β-Amyloid (Aβ) fibrils have recently been considered as a pathologically relevant factor in Alzheimer’s...
Biomolecules, Vol. 10, Pages 879: Premna odorata: Seasonal Metabolic Variation in the Essential Oil Composition of Its Leaf and Verification of Its Anti-Ageing Potential via In Vitro Assays and Molecular Modelling Biomolecules doi: 10.3390/biom10060879 Authors: Ahmed E. Altyar Mohamed L. Ashour Fadia S. Youssef The metabolic variation in the essential oil composition of Premna odorata leaves obtained from different seasons was quantitatively and qualitatively determined employing...
Biomolecules, Vol. 10, Pages 878: High-Throughput Identification of Adapters in Single-Read Sequencing Data Biomolecules doi: 10.3390/biom10060878 Authors: Asan M.S.H. Mohideen Steinar D. Johansen Igor Babiak Sequencing datasets available in public repositories are already high in number, and their growth is exponential. Raw sequencing data files constitute a substantial portion of these data, and they need to be pre-processed for any downstream analyses. The removal of adapter...
Biomolecules, Vol. 10, Pages 876: PSIONplusm Server for Accurate Multi-Label Prediction of Ion Channels and Their Types Biomolecules doi: 10.3390/biom10060876 Authors: Jianzhao Gao Hong Wei Alberto Cano Lukasz Kurgan Computational prediction of ion channels facilitates the identification of putative ion channels from protein sequences. Several predictors of ion channels and their types were developed in the last quindecennial. While they offer reasonably accurate predictions,...
Biomolecules, Vol. 10, Pages 877: Fibrinogen Glycation and Presence of Glucose Impair Fibrin Polymerization—An In Vitro Study of Isolated Fibrinogen and Plasma from Patients with Diabetes Mellitus Biomolecules doi: 10.3390/biom10060877 Authors: Boguslawa Luzak Magdalena Boncler Marcin Kosmalski Ewelina Mnich Lidia Stanczyk Tomasz Przygodzki Cezary Watala Background: Fibrin formation and structure may be affected by a plethora of factors, including both genetic and posttranslational...
Biomolecules, Vol. 10, Pages 875: MYB Superfamily in Brassica napus: Evidence for Hormone-Mediated Expression Profiles, Large Expansion, and Functions in Root Hair Development Biomolecules doi: 10.3390/biom10060875 Authors: Pengfeng Li Jing Wen Ping Chen Pengcheng Guo Yunzhuo Ke Mangmang Wang Mingming Liu Lam-Son Phan Tran Jiana Li Hai Du MYB proteins are involved in diverse important biological processes in plants. Herein, we obtained the MYB superfamily from...
Biomolecules, Vol. 10, Pages 874: Advances and Prospects of Phenolic Acids Production, Biorefinery and Analysis Biomolecules doi: 10.3390/biom10060874 Authors: Egle Valanciene Ilona Jonuskiene Michail Syrpas Ernesta Augustiniene Paulius Matulis Andrius Simonavicius Naglis Malys Biotechnological production of phenolic acids is attracting increased interest due to their superior antioxidant activity, as well as other antimicrobial, dietary, and health benefits. As secondary...
Biomolecules, Vol. 10, Pages 873: Human Telomerase RNA: Telomerase Component or More? Biomolecules doi: 10.3390/biom10060873 Authors: Rubtsova Dontsova Telomerase is a ribonucleoprotein complex that maintains the lengths of telomeres. Most studies of telomerase function have focused on the involvement of telomerase activation in the immortalization of cancer cells and cellular rejuvenation. However, some studies demonstrated that the results do not meet expectations for telomerase...
Biomolecules, Vol. 10, Pages 872: Crystal Structure of a Variant PAM2 Motif of LARP4B Bound to the MLLE Domain of PABPC1 Biomolecules doi: 10.3390/biom10060872 Authors: Grimm Pelz Schneider Schäffler Fischer Eukaryotic cells determine the protein output of their genetic program by regulating mRNA transcription, localization, translation and turnover rates. This regulation is accomplished by an ensemble of RNA-binding proteins (RBPs) that bind to any given mRNA, thus...
Biomolecules, Vol. 10, Pages 871: Yeast Sphingolipid-Enriched Domains and Membrane Compartments in the Absence of Mannosyldiinositolphosphorylceramide Biomolecules doi: 10.3390/biom10060871 Authors: Bento-Oliveira Santos Marquês Paulo Korte Herrmann Marinho de Almeida The relevance of mannosyldiinositolphosphorylceramide [M(IP)2C] synthesis, the terminal complex sphingolipid class in the yeast Saccharomyces cerevisiae, for the lateral organization of the...
Biomolecules, Vol. 10, Pages 870: Secondary Metabolites from Plants Possessing Inhibitory Properties against Beta-Amyloid Aggregation as Revealed by Thioflavin-T Assay and Correlations with Investigations on Transgenic Mouse Models of Alzheimer’s Disease Biomolecules doi: 10.3390/biom10060870 Authors: Stefanescu Stanciu Luca Paduraru Tamba Alzheimer’s disease is a neurodegenerative disorder for which there is a continuous search of drugs able to reduce or stop...
Biomolecules, Vol. 10, Pages 865: IL-22 Promotes IFN-γ-Mediated Immunity against Histoplasma capsulatum Infection Biomolecules doi: 10.3390/biom10060865 Authors: Morgana K.B. Prado Caroline Fontanari Camila O.S. Souza Luiz G. Gardinassi Karina F. Zoccal Francisco W.G. de Paula-Silva Ana P.F. Peti Carlos A. Sorgi Alyne F.G. Meirelles Simone G. Ramos José C. Alves-Filho Lúcia H. Faccioli Histoplasma capsulatum is the agent of histoplasmosis, one of the...
Biomolecules, Vol. 10, Pages 866: A Day in the Life of the Exon Junction Complex Biomolecules doi: 10.3390/biom10060866 Authors: Lena P. Schlautmann Niels H. Gehring The exon junction complex (EJC) is an abundant messenger ribonucleoprotein (mRNP) component that is assembled during splicing and binds to mRNAs upstream of exon-exon junctions. EJCs accompany the mRNA during its entire life in the nucleus and the cytoplasm and communicate the information about the splicing process and...
Biomolecules, Vol. 10, Pages 868: Heterogeneity of Glucose Transport in Lung Cancer Biomolecules doi: 10.3390/biom10060868 Authors: Martinez Scafoglio Increased glucose uptake is a known hallmark of cancer. Cancer cells need glucose for energy production via glycolysis and the tricarboxylic acid cycle, and also to fuel the pentose phosphate pathway, the serine biosynthetic pathway, lipogenesis, and the hexosamine pathway. For this reason, glucose transport inhibition is an emerging...
Biomolecules, Vol. 10, Pages 867: Anti-Apoptotic and Antioxidant Effects of 3-Epi-Iso-Seco-Tanapartholide Isolated from Artemisia Argyi Against Iodixanol-Induced Kidney Epithelial Cell Death Biomolecules doi: 10.3390/biom10060867 Authors: Dahae Lee Kem Ok Kim Dongho Lee Ki Sung Kang Iodixanol is a non-ionic iso-osmolar contrast agent, but it is a risk factor for kidney damage and increases morbidity and mortality. In this study, we investigated the effect of 9 sesquiterpenes...
Biomolecules, Vol. 10, Pages 869: Chemical Diversity and Biological Activities of Essential Oils from Licaria, Nectrandra and Ocotea Species (Lauraceae) with Occurrence in Brazilian Biomes Biomolecules doi: 10.3390/biom10060869 Authors: Júlia Karla A. M. Xavier Nayara Sabrina F. Alves William N. Setzer Joyce Kelly R. da da Silva Lauraceae species are known as excellent essential oil (EO) producers, and their taxa are distributed throughout the territory of Brazil. This study...
Biomolecules, Vol. 10, Pages 864: Comparative Genomics Determines Strain-Dependent Secondary Metabolite Production in Streptomyces venezuelae Strains Biomolecules doi: 10.3390/biom10060864 Authors: Woori Kim Namil Lee Soonkyu Hwang Yongjae Lee Jihun Kim Suhyung Cho Bernhard Palsson Byung-Kwan Cho Streptomyces venezuelae is well known to produce various secondary metabolites, including chloramphenicol, jadomycin, and pikromycin. Although many strains have been classified...
Biomolecules, Vol. 10, Pages 863: Expedition into Taurine Biology: Structural Insights and Therapeutic Perspective of Taurine in Neurodegenerative Diseases Biomolecules doi: 10.3390/biom10060863 Authors: Mujtaba Aamir Bhat Khurshid Ahmad Mohd Sajjad Ahmad Khan Mudasir Ahmad Bhat Ahmad Almatroudi Safikur Rahman Arif Tasleem Jan Neurodegenerative diseases (NDs) are characterized by the accumulation of misfolded proteins. The hallmarks of protein aggregation in NDs proceed...
Biomolecules, Vol. 10, Pages 862: The Regulatory Role of Key Metabolites in the Control of Cell Signaling Biomolecules doi: 10.3390/biom10060862 Authors: Riccardo Milanesi Paola Coccetti Farida Tripodi Robust biological systems are able to adapt to internal and environmental perturbations. This is ensured by a thick crosstalk between metabolism and signal transduction pathways, through which cell cycle progression, cell metabolism and growth are coordinated. Although several reports...
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