Publication date: Available online 7 June 2020Source: Radiotherapy and OncologyAuthor(s): Dawei Chen, Roshal R. Patel, Vivek Verma, Rishab Ramapriyan, Hampartsoum B. Barsoumian, Maria Angelica Cortez, James W. Welsh
Publication date: Available online 6 June 2020Source: Radiotherapy and OncologyAuthor(s): Vérane Achard, Daniel M. Aebersold, Abdelkarim Said Allal, Nicolaus Andratschke, Brigitta G. Baumert, Karl Thomas Beer, Michael Betz, Thomas Breuneval, Stephan Bodis, Berardino de Bari, Robert Förster, Alessandra Franzetti-pellanda, Matthias Guckenberger, Evelyn Herrmann, Constance Huck, Kaouthar Khanfir, Oscar Matzinger, Nicolas Peguret, Gianfranco Pesce, Paul Martin Putora
Publication date: Available online 6 June 2020Source: Radiotherapy and OncologyAuthor(s): Handoko, Tiara Bunga Mayang Permata, Angela Giselvania, Endang Nuryadi, Steven Octavianus, Vito Filbert Jayalie, Nicholas, Novi Elis Khumaesa, Putri Maharani, Fielda Djuita, I G.A.G. Mahendra Wijaya, Yuddi Wahyono, Sugandi Hartanto, Rika Ruhama, Fathiya Juwita Hanum, Christina Nari Nawangsih P, Elia Aditya Bani Kuncoro, Fatmasari, Ulinta Purwati Pasaribu, Lulus Handayani
Publication date: Available online 5 June 2020Source: Radiotherapy and OncologyAuthor(s): Xin Lian, Jing Shen, Yuliang Sun, Qiu Guan, Tingtian Pang, Zhiwei Yang, Lei He, Tingting Dong, Jie Shen, Fuquan Zhang
Publication date: Available online 5 June 2020Source: Radiotherapy and OncologyAuthor(s): Arnaud Beddok, Valentin Calugaru, Mathieu Minsat, Rémi Dendale, Aurélien De Oliveira, Émilie Costa, Farid Goudjil, Rezart Belshi, Noelle Pierrat, Christophe Rochas, Anne Catherine Gravigny, Lucas Soisick, Hélène Colella Fleury, Gilles Créhange
Publication date: Available online 5 June 2020Source: Radiotherapy and OncologyAuthor(s): Johannes H.A.M. Kaanders, Sven van den Bosch, Tim Dijkema, Abrahim Al-Mamgani, Cornelis P.J. Raaijmakers, Wouter V. Vogel
Publication date: Available online 4 June 2020Source: Radiotherapy and OncologyAuthor(s): David G. Kirsch, Maximilian Diehn, Francis A. Cucinotta, Ralph Weichselbaum
Publication date: Available online 4 June 2020Source: Radiotherapy and OncologyAuthor(s): Ian S. Boon, Tracy P.T. Au Yong, Cheng S. Boon
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Abstract Purpose To investigate the optimal contact time and concentration for viricidal activity of oral preparation of povidone‐iodine (PVP‐I) against SARS‐CoV‐2 (‘corona virus’) to mitigate the risk and transmission of the virus in the dental practice. Materials and Methods The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) USA‐WA1/2020 strain, virus stock was tested against oral antiseptic solutions consisting of aqueous povidone‐iodine (PVP‐I) as the sole active ingredient....
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Abstract Purpose Neurofibromatosis type 1 (NF1) syndrome is a common rare/orphan disease that manifests itself early in the paediatric age. It imposes a considerable burden upon patients as well as on caregivers. Decisions regarding optimal care often rely on several medical instances working together as a team. Methods The authors reviewed the literature...
Abstract Introduction Hemangioblastomas are rare, histologically benign, highly vascularized tumors of the brain, the spinal cord, and the retina, occurring sporadically or associated with the autosomal dominant inherited von Hippel-Lindau (VHL) disease. Children or adults with VHL disease have one of > 300 known germline mutations of the VHL gene located on chromosome 3. They are prone to develop hemangioblastomas, extremely rarely...
Abstract Introduction Peripheral nerve sheath tumours in children are a rare and heterogeneous group, consisting mostly of benign tumours as well as malignant neoplasms. Especially in the paediatric population, diagnostics and indication for therapy pose relevant challenges for neurosurgeons and paediatric neurologists alike. Most paediatric cases that need surgical intervention are associated to neurofibromatosis type 1 (NF1). ...
Abstract Intracranial abscess in the pediatric population is an overall rare occurrence—4 in a million. The most common predisposing factor is underlying cyanotic congenital heart disease (CCHD), which is associated with ~ 30% of all cases. We present an unusual case of cerebral abscess in a 17-month-old female with partially treated Tetralogy of Fallot and fever of unknown origin without associated neurologic symptoms. We propose a low threshold for intracranial imaging as part...
Abstract The prevalence of hydrocephalus among patients with neurofibromatosis type I (NF1) is estimated to be between 1 and 13%. Most hydrocephalic causes are obstructive—aqueductal webs, chiasmatic-hypothalamic tumors, and thalamic mass effect related to NF changes. Other NF1-related conditions may mimic the clinical presentation of hydrocephalus and should be ruled out while evaluating children with headaches. These include brain tumors and moyamoya syndrome. Treatment of NF1-related...
Abstract Purpose This study aims to describe a new baclofen pump implantation technique with pre-brainstem catheter placement and to demonstrate the benefits that this procedure has in treating spasticity and dystonia. Methods We described a new technique to place a baclofen pump catheter anterior to the brainstem. To illustrate the technique, we presented...
Abstract Osmotic demyelination syndrome (ODS) is a very rare condition in childhood occurring usually secondary to the rapid increase of serum sodium levels. This situation occurring secondary to the rapid correction of hyponatremia can be seen more rarely in the form of extrapontine myelinolysis and even the coexistence of these two conditions besides central pontine demyelinolysis. However, osmotic demyelination syndrome due to the rapid correction of hyponatremia in chronic...
Abstract Purpose Modern pediatric neurosurgery succeeded in reducing ventricle-peritoneal shunt malfunctions and shunt revisions. However, some children may be submitted to many surgeries, posing burden to their caregivers. And most of caregiver assume responsibility for care without emotional preparation. It is up to health professionals to carry out the educational process. The aim of this study was to evaluate the knowledge, attitude,...
Abstract Background Cleidocranial dysostosis (CCD) is an anomaly characterized by delayed closure of the cranial sutures, midface hypoplasia, moderately short stature, hypoplastic or aplastic clavicles, dental abnormalities, and other complications. Case presentation We report a case of posterior fossa subdural hematoma (PFSDH) after vaginal delivery...
Abstract Purpose The present study aimed to explore the subependymal layers overlying the cerebral ventricles using magnetic resonance imaging. Methods A total of 69 outpatients underwent constructive interference in steady-state (CISS) sequence in thin-sliced, coronal, and sagittal sections. ...
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Abstract Background/aims Jackhammer esophagus (JE) is a hypercontractile esophageal motor disorder defined by at least two swallows with a distal contractile integral (DCI) >8000 mm Hg.s.cm during high‐resolution manometry (HRM). The relationship between symptoms and hypercontractility and the response to therapies have been poorly evaluated. The aim of this study was to determine the clinical presentation, manometric diagnosis, and therapeutic results in a large cohort of JE patients. ...
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Abstract Purpose Although the tibial rotation axis is significant in knee arthroplasty, no reliable extraarticular landmark has been proposed. We hypothesized that the tibial lateral axis (TLA), a tangential line of the lateral tibial surface, is perpendicular to the surgical epicondylar axis (SEA) and compared it to other existing landmarks by 3D-CT. Methods ...
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Abstract Background Cancer genome profiling of cytology specimens using next‐generation sequencing (NGS) requires adequate and good‐quality DNA. Genomic examination of cytology samples was conventionally performed on cell block (CB) or smear specimens than on residual liquid‐based cytology (LBC) specimens, which are high‐quality DNA sources even after long‐term storage. Methods We estimated tumor fractions of 37 residual LBC specimens, including 30 fine needle aspiration (FNA) samples from...
Abstract Background Carcinoma of the gall bladder is the most common malignancy of the biliary tract. Ultrasonography guided Fine Needle Aspiration Cytology (FNAC) plays a crucial role in early detection of gall bladder (GB) lesions. Early diagnosis of GB lesions is a necessity in view of rising trend in GB carcinoma related mortality in India. The aim of this study is to determine the diagnostic accuracy of pre‐operative ultrasonography guided FNAC in the diagnosis of GB masses. Methods...
Abstract Background Salivary gland fine needle aspiration (FNA) has a well‐established role in the evaluation of salivary gland lesions. The Milan system for reporting salivary gland cytopathology (MSRSGC) was developed in 2018 to accomplish a standardized reporting across institutions. This classification is predominantly based on the use of direct smears. This single center study aims to evaluate and further validate the MSRSGC based on the sole use of cell blocks and carry out a risk assessment...
Abstract Fine needle aspiration (FNA), the cornerstone of diagnosis in thyroid swellings, fails to render a definitive diagnosis in about 20% to 30% of cases that are reported as indeterminate on cytology. Since the clinical management in thyroid rests on the risk of malignancy (ROM) in a given nodule, this distinction between “benign” and “possibly malignant” assumes paramount clinical importance. Over the last two decades, tremendous progress has been achieved in our understanding of the molecular...
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Daxor Corporation, a company based in New York, has developed the BVA-100, a blood volume analysis test. The test is the first to be FDA approved for the quantification of blood volume and composition. Following the injection of a radio-labeled tracer, a blood sample is obtained from the patient and analyzed. The entire process takes less than one hour and provides clinicians with information on total blood volume, red blood cell volume, and plasma volume. Blood volume adjustments are important...
Manufacturing artificial red blood cells may turn out to be significant in treating a number of diseases and conditions. This has been tried in the past by a number of teams, but some important functions were missing in every design. Now, a team of scientists at the University of New Mexico have developed artificial red blood cells that can perform all the main functions of the real cells that they mimic. The artificial cells, which are as squeezable as the real ones, can carry hemoglobin,...
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Abstract Medicine can be broadly divided into two fields: clinical medicine that aims to save existing patients and basic medical research that aims to save the lives of future patients. In terms of disseminating basic medical research, medical journals play a vital role for physicians and scientists, as they enable them to share experiences. The author, who has been serving as an Associate Editor of the Brazilian journal Acta Cirurgica Brasileira over a long period of time, wishes to encourage physicians...
Abstract Medicine can be broadly divided into two fields: clinical medicine that aims to save existing patients and basic medical research that aims to save the lives of future patients. In terms of disseminating basic medical research, medical journals play a vital role for physicians and scientists, as they enable them to share experiences. The author, who has been serving as an Associate Editor of the Brazilian journal Acta Cirurgica Brasileira over a long period of time, wishes to encourage physicians...
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Abstract Purpose To determine outcomes and toxicities after reirradiation for locally recurrent nasopharyngeal carcinoma (rNPC) and to apply a prognostic index in a non-endemic region. Methods We retrospectively reported progression-free survival (PFS), overall survival (OS), and treatment-related toxicities in patients treated with curative intent...
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Publication date: Available online 8 June 2020Source: NeuroImageAuthor(s): Subechhya Pradhan, Kushal Kapse, Marni Jacobs, Nickie Niforatos-Andescavage, Jessica Lynn Quistorff, Catherine Lopez, Kathryn Lee Bannantine, Nicole Reinholdt Andersen, Gilbert Vezina, Catherine Limperopoulos
Publication date: Available online 6 June 2020Source: NeuroImageAuthor(s): Juan P. Ramirez-Mahaluf, Vicente Medel, Ángeles Tepper, Luz Maria Alliende, Joao R. Sato, Tomas Ossandon, Nicolas A. Crossley
Publication date: Available online 6 June 2020Source: NeuroImageAuthor(s): Pierrick Coupé, Boris Mansencal, Michaël Clément, Rémi Giraud, Baudouin Denis de Senneville, Vinh-Thong Ta, Vincent Lepetit, José V. Manjon
Publication date: Available online 6 June 2020Source: NeuroImageAuthor(s): Lucilla Lanzoni, Daniela Ravasio, Hannah Thompson, Deniz Vatansever, Daniel Margulies, Jonathan Smallwood, Elizabeth Jefferies
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