A Rare Nasopharyngeal Presentation of Amyloidosis.

A Rare Nasopharyngeal Presentation of Amyloidosis.:

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A Rare Nasopharyngeal Presentation of Amyloidosis.

Ear Nose Throat J. 2020 Mar 30;:145561320914432

Authors: Crosetti E, Manca A, Maldi E, Succo G

Abstract

Amyloidosis is a heterogeneous group of diseases characterized by the extracellular deposition of insoluble proteins whose pathogenesis is not yet fully understood. The deposition of amyloid proteins can be systemic or localized, idiopathic or related to systemic diseases, mostly multiple myeloma or chronic inflammatory diseases. Localized head and neck amyloidosis is a rare entity, mainly involving the larynx. Given the rarity of the disease and the absence of a lasting follow-up protocol, there is no standard treatment defined for localized amyloidosis. We report a rare case of localized nasopharyngeal amyloidosis, treated with complete transoral resection and confirmed by histological examination.

PMID: 32228034 [PubMed - as supplied by publisher]