Related ArticlesTumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy. Oncoimmunology. 2020;9(1):1730538 Authors: Georganaki M, Ramachandran M, Tuit S, Núñez NG, Karampatzakis A, Fotaki G, van Hooren L, Huang H, Lugano R, Ulas T, Kaunisto A, Holland EC, Ellmark P, Mangsbo SM, Schultze J, Essand M, Tugues S, Dimberg A Abstract CD40-stimulating immunotherapy...
Thu Apr 02, 2020 14:26
Related ArticlesThe power of deep learning to ligand-based novel drug discovery. Expert Opin Drug Discov. 2020 Mar 31;:1-10 Authors: Baskin II Abstract Introduction: Deep discriminative and generative neural-network models are becoming an integral part of the modern approach to ligand-based novel drug discovery. The variety of different architectures of neural networks, the methods of their training, and the procedures of generating new molecules require...
Thu Apr 02, 2020 14:26
Related ArticlesApproaches for designing and discovering purinergic drugs for gastrointestinal diseases. Expert Opin Drug Discov. 2020 Mar 31;:1-17 Authors: Dal Ben D, Antonioli L, Lambertucci C, Spinaci A, Fornai M, D'Antongiovanni V, Pellegrini C, Blandizzi C, Volpini R Abstract Introduction: Purines finely modulate physiological motor, secretory, and sensory functions in the gastrointestinal tract. Their activity is mediated by the purinergic signaling...
Thu Apr 02, 2020 14:26
Related ArticlesSynthetic lethality on drug discovery: an update on cancer therapy. Expert Opin Drug Discov. 2020 Mar 31;:1-10 Authors: Yar MS, Haider K, Gohel V, Siddiqui NA, Kamal A Abstract Introduction: A novel anticancer therapy is the need of the hour due to growing incidences of resistance to first line cancer chemotherapy. Synthetic lethality (SL) is one of the new age treatment methods being explored for combating the resistance to anticancer...
Thu Apr 02, 2020 14:26
Related ArticlesSurface plasmon resonance, Orbitrap mass spectrometry and Raman advancements: exciting new techniques in drug discovery. Expert Opin Drug Discov. 2020 Mar 31;:1-4 Authors: Jadhav GP, Prathipati PK, Chauhan H PMID: 32228102 [PubMed - as supplied by publisher]
Thu Apr 02, 2020 14:26
Related ArticlesBreastfeeding and child survival from 0 to 5 years in Côte d'Ivoire. J Health Popul Nutr. 2020 Mar 30;39(1):5 Authors: Yapo YV Abstract BACKGROUND: One of the main objectives of health policy-makers is to promote children's growth, development, and survival. The current research evaluates the impact of breastfeeding on infant survival and highlights the major socio-economic determinants of child survival from 0 to 5 years old in Côte...
Thu Apr 02, 2020 14:26
Related ArticlesOur Response to COVID-19 as Endocrinologists and Diabetologists. J Clin Endocrinol Metab. 2020 May 01;105(5): Authors: Kaiser UB, Mirmira RG, Stewart PM PMID: 32232480 [PubMed - in process]
Thu Apr 02, 2020 14:21
Related ArticlesVery infrequent zoledronate therapy - Somehow still promisingly effective. J Clin Endocrinol Metab. 2020 Mar 31;: Authors: Farr JN PMID: 32232405 [PubMed - as supplied by publisher]
Thu Apr 02, 2020 14:21
Related ArticlesSemaglutide in Cystic Fibrosis-Related Diabetes. J Clin Endocrinol Metab. 2020 Mar 31;: Authors: Gnanapragasam H, Mustafa N, Bierbrauer M, Andrea Providence T, Dandona P Abstract CONTEXT AND OBJECTIVE: In spite of the evidence that inadequately controlled glycemia is associated with worse clinical outcomes, CFRD is not well controlled in a majority of patients. The objective of this report is to demonstrate the effect of the addition...
Thu Apr 02, 2020 14:21
Related ArticlesUsing Kisspeptin to Predict Pubertal Outcomes for Youth with Pubertal Delay. J Clin Endocrinol Metab. 2020 Mar 31;: Authors: Chan YM, Lippincott MF, Sales Barroso P, Alleyn C, Brodsky J, Granados H, Roberts SA, Sandler C, Srivatsa A, Seminara SB Abstract CONTEXT: The management of youth with delayed puberty is hampered by difficulty in predicting who will eventually progress through puberty and who will fail to attain adult reproductive...
Thu Apr 02, 2020 14:21
Related ArticlesDemethylation status of somatic DNA extracted from pituitary neuroendocrine tumors indicates proliferative behavior. J Clin Endocrinol Metab. 2020 Mar 31;: Authors: Szabó B, Németh K, Mészáros K, Szücs N, Czirják S, Reiniger L, Rajnai H, Krencz I, Karászi K, Krokker L, Patócs A, Butz H Abstract BACKGROUND: Cytosine intermediers 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) as epigenetic hallmarks have never been investigated...
Thu Apr 02, 2020 14:21
Related ArticlesShort-term high-fat overfeeding does not induce NF-κB inflammatory signaling in subcutaneous white adipose tissue. J Clin Endocrinol Metab. 2020 Mar 31;: Authors: Dewhurst-Trigg R, Wadley AJ, Woods RM, Sherar LB, Bishop NC, Hulston CJ, Markey O Abstract CONTEXT: It is unclear how white adipose tissue (WAT) inflammatory signaling proteins respond during the early stages of overnutrition. OBJECTIVE: To investigate the effect of...
Thu Apr 02, 2020 14:21
Related ArticlesAcute Effects of Glucagon on Reproductive Hormone Secretion in Healthy Men. J Clin Endocrinol Metab. 2020 Mar 31;: Authors: Izzi-Engbeaya C, Jones S, Crustna Y, Machenahalli PC, Papadopoulou D, Modi M, Starikova J, Chan D, Eng PC, Phylactou M, Ratnasabathy R, Mills E, Yang L, Pacuszka E, Bech P, Minnion J, Tharakan G, Tan T, Veldhuis J, Abbara A, Comninos AN, Dhillo WS Abstract CONTEXT: Glucagon increases energy expenditure; consequently,...
Thu Apr 02, 2020 14:21
Related ArticlesElectroacupuncture mimics exercise-induced changes in skeletal muscle gene expression in polycystic ovary syndrome women. J Clin Endocrinol Metab. 2020 Mar 31;: Authors: Benrick A, Pillon NJ, Nilsson E, Lindgren E, Krook A, Ling C, Stener-Victorin E Abstract CONTEXT: Autonomic nervous system activation mediates the increase in whole-body glucose uptake in response to electroacupuncture but the mechanisms are largely unknown. ...
Thu Apr 02, 2020 14:21
Related ArticlesGermline CDKN1B loss-of-function variants cause pediatric Cushing's disease with or without an MEN4 phenotype. J Clin Endocrinol Metab. 2020 Mar 31;: Authors: Chasseloup F, Pankratz N, Lane J, Faucz FR, Keil MF, Chittiboina P, Kay DM, Hussein Tayeb T, Stratakis CA, Mills JL, Hernández-Ramírez LC Abstract CONTEXT: Germline loss-of-function CDKN1B gene variants cause the autosomal dominant syndrome of multiple endocrine neoplasia type 4...
Thu Apr 02, 2020 14:21
Related Articlescentral adrenal insufficiency is rare in adults with Prader-Willi syndrome. J Clin Endocrinol Metab. 2020 Mar 31;: Authors: Rosenberg AGW, Pellikaan K, Poitou C, Goldstone AP, Høybye C, Markovic T, Grugni G, Crinò A, CaixàS A, Coupaye M, Van Den Berg SAA, Van Der Lely AJ, De Graaff LCG Abstract CONTEXT: Prader-Willi syndrome (PWS) is associated with several hypothalamic-pituitary hormone deficiencies. There is no agreement on the prevalence...
Thu Apr 02, 2020 14:21
Abstract Purpose To evaluate effectiveness of the apparent diffusion coefficient (ADC) values of the peripancreatic lymphadenopathy to differentiate tuberculous lymphadenopathy from metastatic lymphadenopathy. Materials and methods Twenty-nine patients with 65 peripancreatic necrotic tuberculous lymphadenopathy and 31 patients with 47 peripancreatic necrotic...
Thu Apr 02, 2020 03:00
Related ArticlesRadiology Department Preparedness for COVID-19: Facing an Unexpected Outbreak of the Disease. Radiology. 2020 Mar 31;:201214 Authors: Orsi MA, Oliva AG, Cellina M PMID: 32228364 [PubMed - as supplied by publisher]
Thu Apr 02, 2020 14:18
Related ArticlesCOVID-19-associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features. Radiology. 2020 Mar 31;:201187 Authors: Poyiadji N, Shahin G, Noujaim D, Stone M, Patel S, Griffith B PMID: 32228363 [PubMed - as supplied by publisher]
Thu Apr 02, 2020 14:18
Related Articles3D CT of Novel Coronavirus (COVID-19) Pneumonia. Radiology. 2020 Mar 31;:201183 Authors: Ufuk F Abstract This article has online supplemental material.PMID: 32228362 [PubMed - as supplied by publisher]
Thu Apr 02, 2020 14:18
Related ArticlesCombining Volumetric and Wall Shear Stress Analysis from CT to Assess Risk of Abdominal Aortic Aneurysm Progression. Radiology. 2020 Mar 31;:192112 Authors: Meyrignac O, Bal L, Zadro C, Vavasseur A, Sewonu A, Gaudry M, Saint-Lebes B, De Masi M, Revel-Mouroz P, Sommet A, Darcourt J, Negre-Salvayre A, Jacquier A, Bartoli JM, Piquet P, Rousseau H, Moreno R Abstract Background Despite known limitations, the decision to operate on abdominal...
Thu Apr 02, 2020 14:18
Related ArticlesVolume Doubling Times of Lung Adenocarcinomas: Correlation with Predominant Histologic Subtypes and Prognosis. Radiology. 2020 Mar 31;:191835 Authors: Park S, Lee SM, Kim S, Lee JG, Choi S, Do KH, Seo JB Abstract Background The volume doubling time (VDT) is a key parameter in the differentiation of aggressive tumors from slow-growing tumors. How different histologic subtypes of primary lung adenocarcinomas vary in their VDT and the...
Thu Apr 02, 2020 14:18
Related ArticlesMuscle-invasive Urothelial Cancer: Association of Mutational Status with Metastatic Pattern and Survival. Radiology. 2020 Mar 31;:191770 Authors: Alessandrino F, Williams K, Nassar AH, Gujrathi R, Silverman SG, Sonpavde G, Shinagare AB Abstract Background Muscle-invasive urothelial cancer (MIUC) is characterized by substantial genetic heterogeneity and high mutational frequency. Correlation between frequently mutated genes with clinical...
Thu Apr 02, 2020 14:18
Related ArticlesMultiphase Liver MRI for Identifying the Macrotrabecular-Massive Subtype of Hepatocellular Carcinoma. Radiology. 2020 Mar 31;:192230 Authors: Mulé S, Galletto Pregliasco A, Tenenhaus A, Kharrat R, Amaddeo G, Baranes L, Laurent A, Regnault H, Sommacale D, Djabbari M, Pigneur F, Tacher V, Kobeiter H, Calderaro J, Luciani A Abstract Background The recently described "macrotrabecular-massive" (MTM) histologic subtype of hepatocellular...
Thu Apr 02, 2020 14:18
Related ArticlesKinetic Heterogeneity of Breast Cancer Determined Using Computer-aided Diagnosis of Preoperative MRI Scans: Relationship to Distant Metastasis-Free Survival. Radiology. 2020 Mar 31;:192039 Authors: Kim JY, Kim JJ, Hwangbo L, Suh HB, Kim S, Choo KS, Nam KJ, Kang T Abstract Background Higher peak enhancement and washout component values measured on preoperative breast MRI scans with computer-aided diagnosis (CAD) are presumed to be...
Thu Apr 02, 2020 14:18
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