Rejuvenation Research, Volume 23, Issue 2, Page 159-170, April 2020.
Fri Apr 17, 2020 10:00
Abstract Abamectin (ABA) constitutes a big commodity for pharmaceutical companies because it generates about one billion dollar annual sale. Avermectins (AVMs) and their naturally occurring analogues, milbemycins (MILs), meilingmycins (MEIs), ivermectin (IVE), abamectin (ABA), and nemadectin (NEM), represent one of the most developed antiparasitic agents. Abamectin is a mixture of avermectin B1a and avermectin B1b. The production of abamectin by Streptomyces avermitilis is a complicated...
Thu Apr 23, 2020 03:00
Adapting to our new circumstances is necessary, and the earlier we start, the better off we are. There is a lot of reason for hope, but be prepared for the bad news as well.
Tue Apr 21, 2020 21:52
Since February 2020, as U.S. public health efforts have focused on containing the spread of COVID-19, gun sales in the country have skyrocketed, physical distancing necessary to curb transmission has disrupted social networks, and Americans have faced an unprecedented combination of a public health and economic disaster. Combined, these forces create a climate with the potential to increase firearm-related suicides.
Wed Apr 22, 2020 03:00
Tue Apr 21, 2020 03:00
Clearly, when people think who might be at high risk of complications from COVID-19, they do not think of me. Why would someone in their mid-thirties with no elders at home be worried about Coronavirus? Aside from the mounting evidence that younger people have had serious complications related to COVID-19, I meet not one but three CDC categories for “higher risk of severe illness”: 1) moderate to severe asthma, 2) being immunocompromised, and 3) a BMI over 40. The second of these has given me hard-earned...
Wed Apr 22, 2020 21:30
Heather Lazrus is an environmental anthropologist who studies perceptions of and responses to extreme weather in the context of a changing climate. Image description: An illustrated portrait of a woman’s torso, with long dark hair, and wearing a green shirt. In the background leaves and clouds swirl across patches of blue sky. Charlotte Hollands1. The complexity of the current climate crisis demands multiple disciplines working together to innovate creative solutions. Understanding diverse disciplinary...
Wed Apr 22, 2020 18:31
IPCC reports are hailed as objective, empirical evidence. But the social life of their production and circulation has much to do with conflicting politics, values, and choices. In early fall of 2019, Swedish climate activist Greta Thunberg made a well-publicized tour of the United States, including a stop in Washington, DC, to appear before Congress. The usually staid hearing room filled with young people who had come to hear her, and reporters crowded in for a photo of the diminutive teenager....
Wed Apr 22, 2020 18:29
In New York, the sustainable city is being built on its own undoing. In 2014, residents of Staten Island’s Elm Park neighborhood found their cars covered in dust. Periodic blasts shook their homes. Construction noise dinned all day and often all night. The air smelled of diesel, thanks to a never-ending line of trucks waiting to cross into New Jersey. Throughout that summer, the Port Authority of New York and New Jersey (PANYNJ) instructed residents to keep windows closed. After several months and...
Wed Apr 22, 2020 18:27
The Antarctic ice sheets are losing mass at an accelerating rate. How do scientists explain and engage with this increasingly urgent climate crisis? Antarctic ice looms. Literally. Much of the ice edge of Antarctica is made up of massive cliffs, its size and expanse almost incomprehensible from photographs. The Ross Ice Shelf, for example, is more than 370 miles long and stands starkly up to 160 feet high, a barrier into the continent. It also looms as a threat to coastlines, the settlements built...
Wed Apr 22, 2020 18:25
In 2018, a wildfire swept through Northern California. Forensic anthropologists were called in to identify skeletal remains in a devastated recovery scene. In a smoke-filled parking lot, our team of anthropologists lined up, outfitted in protective gear and ready to receive search and recovery assignments for the day. After a long morning of planning, we climbed into small buses to travel to the fire-ravaged town of Paradise. The bus dodged downed power lines and drove around burned trees in the...
Wed Apr 22, 2020 18:23
For women of color on Louisiana’s Gulf Coast, everyday environmental and climate activism is entangled with intimate lives. It is April, and it is hot and humid in New Orleans. I am on my way to the Broad Theatre to watch My Louisiana Love, a documentary produced by Indigenous storyteller Monique Verdin. This is the first day of the first annual Fossil Free Fest, a week of art, food, music, film screenings, and conversation. The fest is dedicated to creating an open space for Gulf Coast communities...
Wed Apr 22, 2020 18:21
The deterministic view that climate change invariably causes migration, competition, violence, and collapse is overly simplistic. Bioarchaeology shows us that human responses are far more complex and diverse. My husband turned to me recently and lamented, “Have you seen what is happening in Italy right now? It’s like the Middle Ages!” Today one-third of the global community is “sheltering in place” in their homes as we try to reduce the spread of COVID-19. My husband was referring to the moment...
Wed Apr 22, 2020 18:19
To navigate the growing storms of climate change, St. Croix is doubling down on the fiscal promise of oil. Residents demand otherwise. St. Croix stands at a climate crucible. For 50 years, a massive oil refinery underwrote economic development on this US territory in the Caribbean before the plant closed abruptly in 2012. Today, the aftershocks of fossil fuels—whether in a legacy of toxic pollution or the rising fury of superstorms—threaten life on St. Croix. Facing up to these challenges is a...
Wed Apr 22, 2020 18:17
In 2014, the first of Iceland’s named glaciers suffered death by human-made climate change. Two anthropologists decided to mark its passing. Sometime around the year 2000, no one knows exactly when, something small died in Iceland. Its name was Ok. And it was a glacier. Ok was relatively slight and not particularly handsome as Icelandic glaciers go. It hadn’t received much attention from Icelanders during its 700-year life. But Icelandic children did learn about it in school and some recalled laughing...
Wed Apr 22, 2020 18:15
Abstract Background This pilot study was part of a larger study which compared the effect of subgingival air-polishing using trehalose powder with sonic scaling on clinical parameters during supportive periodontal therapy. Within this microbiological part of the investigation subgingival samples were taken from 10 participants to analyze the survival of different bacterial species after the two different treatments as a proof...
Wed Apr 22, 2020 03:00
Abstract Background Dental sealants have been covered by the National Health Insurance Service (NHIS) since December 2009 in South Korea. This study aims to determine whether the socioeconomic inequality in untreated dental caries decreased after implementing the extended coverage policy for dental sealant. Methods The data were derived...
Wed Apr 22, 2020 03:00
Abstract In 1566, Pedro Menéndez de Avilés arrived at the capital of the Calusa kingdom. During that same year Menéndez issued the order to construct Fort San Antón de Carlos, which was occupied until 1569. This fort was also the location of one of the first Jesuit missions (1567) in what is now the United States. We now can confirm what archaeologists and historians have long suspected: the location of the fort and the capital of the Calusa was Mound Key (8LL2), located in Estero...
Wed Apr 22, 2020 03:00
Abstract Radon therapy has been traditionally performed globally for oxidative stress-related diseases. Many researchers have studied the beneficial effects of radon exposure in living organisms. However, the effects of thoron, a radioisotope of radon, have not been fully examined. In this study, we aimed to compare the biological effects of radon and thoron inhalation on mouse organs with a focus on oxidative stress. Male BALB/c mice were randomly divided into 15 groups: sham...
Wed Apr 22, 2020 03:00
The original article [1] contains errors in Table 1 in rows ktrans and Ve; the correct version of Table 1 can be viewed in this Correction article.
Wed Apr 22, 2020 03:00
Abstract Apical periodontitis (AP) is an inflammatory disease caused by bacteria infection and is regarded as a common disease in the world. In the progression of AP, the function of nucleotide-binding oligomerization, leucine-rich repeat and pyrin domain domains-containing protein 3 (NLRP3) inflammasome has been revealed. Although tripartite motif 31 (TRIM31) has been suggested to regulate many chronic inflammations by mediating NLRP3 inflammasome, such mechanism in AP remains...
Wed Apr 22, 2020 03:00
Abstract Purpose of Review We performed this study and associated review to examine whether a one prognostic block is sufficient to proceed with radiofrequency ablation. Recent Findings To perform one or two prognostic blocks before performing radiofrequency ablation is a very controversial issue. The practice is inconsistent and insurance...
Wed Apr 22, 2020 03:00
Abstract Purpose of Review Approximately 20% of patients undergoing surgery develop persistent lower extremity pain following total knee arthroplasty. Animal studies have confirmed that prolonged tourniquet time increases the risk of endoneural ischemia and can mediate or modulate the development of chronic pain. The use of Near InfraRed Spectroscopy (NIRS) adjacent to nerve tissue, previously described as ONG has been shown to...
Wed Apr 22, 2020 03:00
Abstract Purpose of Review The purpose of this manuscript is to provide a comprehensive review of postdural puncture headache (PDPH) with a focus on epidemiology, pathophysiology, treatment, and prophylaxis. Recent Findings PDPH is an adverse iatrogenic complication of neuraxial anesthesia that occurs following inadvertent puncture of...
Wed Apr 22, 2020 03:00
Objective. Inflammation plays an extremely considerable role in the development and progression of malignancies. Absolute neutrophil count (ANC) and mean platelet volume (MPV) in blood are associated with various inflammatory conditions and resulted in independent prognostic factors for lung cancer. However, whether ANC and MPV can be diagnostic markers for lung cancer remains unknown. This retrospective study investigated the roles of ANC and MPV, either alone or combined, in diagnosing lung cancer....
Wed Apr 22, 2020 12:20
Background. Postoperative lymphocyte to monocyte ratio (post-LMR) change (LMRc) reflects the dynamic change of balance between inflammatory reaction and immune reaction after curative operation. An elevated preoperative LMR (pre-LMR) has been shown to be a prognostic factor in patients with esophageal squamous cell carcinoma (ESCC), but the clinical value of the LMRc remains unknown. Methods. 674 patients in ESCC undergoing curative operation were enrolled in this study. LMRc () was counted on the...
Wed Apr 22, 2020 10:35
Mon Apr 20, 2020 22:00
Summary Skin lesions associated with internal malignancy may present as cutaneous metastases or as typical lesions occurring in the context of certain cancer‐associated genetic syndromes. Paraneoplastic syndromes, on the other hand, are only indirectly associated with an underlying malignancy and are not malignant per se. Historically, a distinction has been made between “obligate” and “facultative” paraneoplastic disorders, depending on the likelihood with which they are potentially associated...
Mon Apr 20, 2020 13:30
Summary Background Psoriasis is a chronic, relapsing disease often associated with comorbidities. While its associations with cardiovascular and metabolic factors have been investigated, little is known about its association with impairment of renal function. Materials and methods We performed a cohort study of 219 psoriatic patients in which we evaluated chronic kidney disease (CKD) and eGFR as well as albuminuria according to their KDIGO stratification risk criteria. We also evaluated...
Mon Apr 20, 2020 13:30
Summary To date, there have been only few studies investigating rechallenge with checkpoint inhibitors in melanoma patients. Herein, we present the first review of all internationally published, English‐language articles. A total of 570 patients were included in our analysis, divided into four groups: 1) rechallenge with anti‐PD1 following disease progression on anti‐PD1 therapy; 2) rechallenge with anti‐PD1 and anti‐CTLA4 following disease progression on anti‐PD1 therapy; 3) rechallenge with anti‐CLTA‐4...
Mon Apr 20, 2020 13:30
Journal of Cutaneous Medicine and Surgery, Ahead of Print. BackgroundAccelerators in medical gloves are a common cause of allergic contact dermatitis among healthcare workers.ObjectiveA systematic review of medical and nursing literature, patch testing reports, and chemical analyses of gloves was conducted to assess accelerator contents reported in the literature and to identify accelerator-free gloves.MethodsA systematic literature search was performed in OVID Medline and OVID EMBASE. Hand-searching...
Wed Apr 22, 2020 11:51
Journal of Cutaneous Medicine and Surgery, Ahead of Print. BackgroundAtopic dermatitis (AD) in adults is not uncommon, and its prevalence has been increasing in the recent decades. However, there is a paucity of data about the differences between early-onset and late-onset adult AD.ObjectiveThe objective of this study is to investigate the clinical and laboratory characteristics of adult AD, focusing on the differences between early-onset and late-onset adult AD.MethodsWe retrospectively reviewed...
Wed Apr 22, 2020 11:47
Journal of Cutaneous Medicine and Surgery, Ahead of Print. BackgroundHyaluronic acid (HA) fillers have increased in popularity. While complications are rare, practitioners should focus on their prevention. Preinjection aspiration remains controversial as an effective safety checkpoint.ObjectivesOur study investigated the utility of preinjection aspiration as a safety checkpoint for HA fillers through comparison of physiochemical and rheological properties in a novel in vivo human model.MethodsAn...
Wed Apr 22, 2020 10:34
Hematological malignancies, including chronic myeloid leukemia (CML), exhibit ASXL1 mutations; however, the function and molecular mechanism of these mutations remain unclear. ASXL1 was originally identified as tumor suppressor gene, in which loss of function causes myelodysplastic syndrome (MDS). ASXL1 mutations are common and associated with disease progression in myeloid malignancies including MDS, acute myeloid leukemia, and similarly in CML. In MDS, ASXL1 mutations have been associated with...
Wed Apr 22, 2020 10:25
Neutropenic enterocolitis is a clinical condition characterized by inflammation of the colic mucosa, usually the caecum, associated with bowel wall thickening in patients with compromised immune system due to chemotherapy treatments. It can occur as well in other clinical conditions that lead to immunosuppression. Clinically, patients present with abdominal pain, fever, and neutropenia on blood tests. A number of major and minor criteria have been suggested for the clinical diagnosis of typhlitis....
Wed Apr 22, 2020 10:24
Abstract YouTube is the world's most popular video‐sharing site that in recent years has become an important platform for patients in finding educational information about their disease. The purpose of this study was to assess the quality and reliability of narcolepsy‐related YouTube videos. We searched the key terms “Narcolepsy”, “Narcolepsy‐cataplexy,” “Narcolepsy excessive daytime sleepiness” and “Narcolepsy excessive drowsiness” on YouTube. 80 videos were analyzed as they meet the inclusion...
Tue Apr 21, 2020 16:10
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