Related ArticlesParticipant retention in follow-up studies of prematurely born children. BMC Public Health. 2019 Sep 06;19(1):1233 Authors: MacBean V, Drysdale SB, Zivanovic S, Peacock JL, Greenough A Abstract BACKGROUND: Follow-up studies of infants born prematurely are essential to understand the long-term consequences of preterm birth and the efficacy of interventions delivered in the neonatal period. Retention of participants for follow-up studies,...
Related ArticlesCost-effectiveness of a statewide public health intervention to reduce cardiovascular disease risk. BMC Public Health. 2019 Sep 06;19(1):1234 Authors: Smith L, Atherly A, Campbell J, Flattery N, Coronel S, Krantz M Abstract BACKGROUND: The cost-effectiveness of community health worker (CHW)-based cardiovascular disease (CVD) risk-reduction interventions is not well established. Colorado Heart Healthy Solutions is a CHW-based intervention...
Related ArticlesAcceptability and potential impact of delivering sexual health promotion information through social media and dating apps to MSM in England: a qualitative study. BMC Public Health. 2019 Sep 06;19(1):1236 Authors: Kesten JM, Dias K, Burns F, Crook P, Howarth A, Mercer CH, Rodger A, Simms I, Oliver I, Hickman M, Hughes G, Weatherburn P Abstract BACKGROUND: Increasing rates of sexually transmitted infections (STIs) in men-who-have-sex-with-men...
Patterns of seasonal and pandemic influenza-associated health care and mortality in Ontario, Canada.
Related ArticlesPatterns of seasonal and pandemic influenza-associated health care and mortality in Ontario, Canada. BMC Public Health. 2019 Sep 06;19(1):1237 Authors: Li M, Bolker BM, Dushoff J, Ma J, Earn DJD Abstract BACKGROUND: Mathematical and statistical models are used to project the future time course of infectious disease epidemics and the expected future burden on health care systems and economies. Influenza is a particularly important disease...
Related ArticlesPrevalence of diarrheal diseases and associated factors among under-five children in Dale District, Sidama zone, Southern Ethiopia: a cross-sectional study. BMC Public Health. 2019 Sep 06;19(1):1235 Authors: Melese B, Paulos W, Astawesegn FH, Gelgelu TB Abstract BACKGROUND: Globally childhood diarrhoeal diseases continue to be the second leading cause of death, while in Ethiopia it kills half-million under-five children each year. Sanitation,...
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Related Articlesmycelyso - high-throughput analysis of Streptomyces mycelium live cell imaging data. BMC Bioinformatics. 2019 Sep 04;20(1):452 Authors: Sachs CC, Koepff J, Wiechert W, Grünberger A, Nöh K Abstract BACKGROUND: Streptomycetes are filamentous microorganisms of high biotechnological relevance, especially for the production of antibiotics. In submerged cultures, the productivity of these microorganisms is closely linked to their growth morphology....
Related ArticlesSamPler - a novel method for selecting parameters for gene functional annotation routines. BMC Bioinformatics. 2019 Sep 05;20(1):454 Authors: Cruz F, Lagoa D, Mendes J, Rocha I, Ferreira EC, Rocha M, Dias O Abstract BACKGROUND: As genome sequencing projects grow rapidly, the diversity of organisms with recently assembled genome sequences peaks at an unprecedented scale, thereby highlighting the need to make gene functional annotations...
Related ArticlesFast and accurate average genome size and 16S rRNA gene average copy number computation in metagenomic data. BMC Bioinformatics. 2019 Sep 05;20(1):453 Authors: Pereira-Flores E, Glöckner FO, Fernandez-Guerra A Abstract BACKGROUND: Metagenomics caused a quantum leap in microbial ecology. However, the inherent size and complexity of metagenomic data limit its interpretation. The quantification of metagenomic traits in metagenomic analysis...
Related ArticlesPTPD: predicting therapeutic peptides by deep learning and word2vec. BMC Bioinformatics. 2019 Sep 06;20(1):456 Authors: Wu C, Gao R, Zhang Y, De Marinis Y Abstract *: Background In the search for therapeutic peptides for disease treatments, many efforts have been made to identify various functional peptides from large numbers of peptide sequence databases. In this paper, we propose an effective computational model that uses deep learning...
Related ArticlesSibe: a computation tool to apply protein sequence statistics to predict folding and design in silico. BMC Bioinformatics. 2019 Sep 06;20(1):455 Authors: Cheung NJ, Yu W Abstract BACKGROUND: Evolutionary information contained in the amino acid sequences of proteins specifies the biological function and fold, but exactly what information contained in the protein sequence drives both of these processes? Considerable progress has been made...
Related ArticlesModel annotation and discovery with the Physiome Model Repository. BMC Bioinformatics. 2019 Sep 06;20(1):457 Authors: Sarwar DM, Kalbasi R, Gennari JH, Carlson BE, Neal ML, Bono B, Atalag K, Hunter PJ, Nickerson DP Abstract BACKGROUND: Mathematics and Phy sics-based simulation models have the potential to help interpret and encapsulate biological phenomena in a computable and reproducible form. Similarly, comprehensive descriptions of...
Related ArticlesA novel evolutionary model for constructing gene coexpression networks with comprehensive features. BMC Bioinformatics. 2019 Sep 06;20(1):460 Authors: Gu Y, Zu J, Li Y Abstract BACKGROUND: Uncovering the evolutionary principles of gene coexpression network is important for our understanding of the network topological property of new genes. However, most existing evolutionary models only considered the evolution of duplication genes and...
Related ArticlesVisualization methods for differential expression analysis. BMC Bioinformatics. 2019 Sep 06;20(1):458 Authors: Rutter L, Moran Lauter AN, Graham MA, Cook D Abstract BACKGROUND: Despite the availability of many ready-made testing software, reliable detection of differentially expressed genes in RNA-seq data is not a trivial task. Even though the data collection is considered high-throughput, data analysis has intricacies that require careful...
Related ArticlesMultiple-level biomedical event trigger recognition with transfer learning. BMC Bioinformatics. 2019 Sep 06;20(1):459 Authors: Chen Y Abstract BACKGROUND: Automatic extraction of biomedical events from literature is an important task in the understanding biological systems, allowing for faster update of the latest discoveries automatically. Detecting trigger words which indicate events is a critical step in the process of event extraction,...
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Related ArticlesInorganic ions on hemozoin surface provide a glimpse into Plasmodium biology. J Inorg Biochem. 2019 Aug 27;200:110808 Authors: Guerra ED, Baakdah F, Gourgas O, Tam M, Stevenson MM, Georges E, Bohle DS, Cerruti M Abstract In malaria, Plasmodium parasites produce hemozoin (Hz) as a route to detoxify free heme released from the catabolism of hemoglobin. Hz isolated from the parasites is encapsulated in an organic layer constituted by parasite...
Related ArticlesIn vitro tyrosinase, acetylcholinesterase, and HSA evaluation of dioxidovanadium (V) complexes: An experimental and theoretical approach. J Inorg Biochem. 2019 Aug 29;200:110800 Authors: Chaves OA, de Oliveira MCC, de Salles CMC, Martins FM, Iglesias BA, Back DF Abstract The present study reports the biological evaluation of vanadium(V) complexes (1-3) against three different proteins: tyrosinase, acetylcholinesterase (AChE), and human...
Related ArticlesAddition of sodium ascorbate to extend the shelf-life of tuna meat fish: A risk or a benefit for consumers? J Inorg Biochem. 2019 Aug 26;200:110813 Authors: Howes BD, Milazzo L, Droghetti E, Nocentini M, Smulevich G Abstract We investigate the effects of antimicrobial (sodium citrate tribasic, E331) and antioxidant (ascorbic acid, E300 and sodium ascorbate, E301) additives on the meat drip from defrosted yellowfin tuna fish loins obtained...
Related ArticlesHigh antiparasitic activity of silver complexes of 5,7-dimethyl-1,2,4-triazolo[1,5 a]pyrimidine. J Inorg Biochem. 2019 Aug 29;201:110810 Authors: Esteban-Parra GM, Méndez-Arriaga JM, Rodríguez-Diéguez A, Quirós M, Salas JM, Sánchez-Moreno M Abstract Two dinuclear silver complexes containing 5,7-dimethyl[1,2,4]triazolo[1,5-a]pyrimidine (dmtp) were synthesized, [Ag2(dmtp)3]2[Ag2(dmtp)2](BF4)6(H2O)2 and [Ag2(dmtp)2(ClO4)2][Ag2(dmtp)2(H2O)2](ClO4)2....
Related ArticlesAssembly behavior of amylin fragment hIAPP19-37 regulated by Au(III) complexes. J Inorg Biochem. 2019 Aug 29;201:110807 Authors: Huang X, Xu J, Du W Abstract Human islet amyloid polypeptide (hIAPP, amylin) may self-aggregate and rupture the membrane of β cells, which is closely correlated with the pathogenesis of type 2 diabetes mellitus (T2DM). Hence, suppressing amyloidogenic hIAPP may be beneficial for the treatment of diabetes. As...
Related ArticlesAntiproliferative activity of heterometallic sodium and potassium-dioxidovanadium(V) polymers. J Inorg Biochem. 2019 Aug 27;200:110811 Authors: Sutradhar M, Alegria ECBA, Ferretti F, Raposo LR, Guedes da Silva MFC, Baptista PV, Fernandes AR, Pombeiro AJL Abstract The syntheses of the heterometallic sodium and potassium-dioxidovanadium 2D polymers, [NaVO2(1κNOO';2κO"-L)(H2O)]n(1) and [KVO2(1κNOO';2κO';3κO"-L)(EtOH)]n(2) (where the κ notation...
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Related ArticlesEffects of type 1 diabetes mellitus on efferent auditory system in children and adolescents. Int J Pediatr Otorhinolaryngol. 2019 Aug 25;127:109660 Authors: Braite N, da Cruz Fernandes L, Rissatto Lago MR, de Aragão Dantas Alves C Abstract AIM: To investigate whether type 1 diabetes mellitus (T1DM) could affect the efferent auditory system by analyzing the relationship between the activation of the medial olivocochlear reflex with disease...
Related ArticlesCharacterization of acute otitis media otopathogens before the introduction of the pneumococcal conjugated vaccine into the national immunization program in Poland. Int J Pediatr Otorhinolaryngol. 2019 Aug 31;127:109666 Authors: Górska-Kot A, Greenberg D, Gastoł K, Zieliński A, Givon-Lavi N Abstract BACKGROUND: Bacterial etiologic data for acute otitis media (AOM) otopathogens in Poland are scarce. The aim of this study was to determine...
Related ArticlesSurgical management of midline cervical cleft. Int J Pediatr Otorhinolaryngol. 2019 Aug 23;127:109657 Authors: D'Souza JN, Valika T, Maddalozzo J Abstract INTRODUCTION: Midline Cervical Cleft (MCC) is a midline cervical congenital anomaly that manifests as a vertical cutaneous/subcutaneous defect with abnormal dermal elements as well as an underlying fibrous cord that extends from the sternum to the mentum of the mandible, which can lead...
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Related ArticlesStapes footplate defect as a source of CSF leak and otogenic meningitis in a patient with a cochlear implant. Ear Nose Throat J. 2018 Dec;97(12):E31-E32 Authors: Vartanyan M, Hill F, Orimoto K, O'Leary S PMID: 30540900 [PubMed - indexed for MEDLINE]
Related ArticlesIntrasphenoidal encephalocele (ISE) with spontaneous CSF rhinorrhea in idiopathic intracranial hypertension: A need for clarity in terminology & imaging delineation. World Neurosurg. 2019 Sep 03;: Authors: Manjubashini D, Kiran M, Akshaya S, Nagarajan K Abstract BACKGROUND: Magnetic Resonance (MR) imaging plays an important role in identification of any underlying structural cause in spontaneous cerebrospinal fluid (CSF) leaks - either...
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Related Articles[Clinical Application of New Antiepileptic Drugs]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2019 Aug 30;41(4):566-571 Authors: Wang DL, Song HD, Xu K, Liu R Abstract Epilepsy has high incidence and complex etiologies,and its treatment remains challenging.For around 70% of people with epilepsy,seizures can be controlled after proper antiepileptic treatment.The availability of some new antiepileptic drugs in recent years has offered new options...
Related ArticlesN-Benzyl-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) with Hybrid Structure as a Candidate for a Broad-Spectrum Antiepileptic Drug. Neurotherapeutics. 2019 Sep 04;: Authors: Kamiński K, Socała K, Zagaja M, Andres-Mach M, Abram M, Jakubiec M, Pieróg M, Nieoczym D, Rapacz A, Gawel K, Esguerra CV, Latacz G, Lubelska A, Szulczyk B, Szewczyk A, Łuszczki JJ, Wlaź P Abstract In our recent studies, we identified compound N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide...
Related ArticlesSelf-management for adults with epilepsy: Aggregate Managing Epilepsy Well Network findings on depressive symptoms. Epilepsia. 2019 Sep 05;: Authors: Sajatovic M, Johnson EK, Fraser RT, Cassidy KA, Liu H, Pandey DK, Quarells RC, Scal P, Schmidt S, Shegog R, Spruill TM, Janevic MR, Tatsuoka C, Jobst BC Abstract OBJECTIVE: To assess depressive symptom outcomes in a pooled sample of epilepsy self-management randomized controlled trials (RCTs)...
Related ArticlesDynorphin-based "release on demand" gene therapy for drug-resistant temporal lobe epilepsy. EMBO Mol Med. 2019 Sep 05;:e9963 Authors: Agostinho AS, Mietzsch M, Zangrandi L, Kmiec I, Mutti A, Kraus L, Fidzinski P, Schneider UC, Holtkamp M, Heilbronn R, Schwarzer C Abstract Focal epilepsy represents one of the most common chronic CNS diseases. The high incidence of drug resistance, devastating comorbidities, and insufficient responsiveness...
Related ArticlesClinical Application of Targeted Next-Generation Sequencing Panels and Whole Exome Sequencing in Childhood Epilepsy. Neuroscience. 2019 Sep 02;: Authors: Costain G, Cordeiro D, Matviychuk D, Mercimek-Andrews S Abstract Genetic diagnosis of childhood epilepsy is crucial to provide disease-specific treatments. This report describes the genetic landscape of childhood epilepsy revealed by targeted next-generation sequencing panels for epilepsy...
Related ArticlesTreatment patterns in patients with a new diagnosis of epilepsy and psychiatric comorbidities. Epilepsy Behav. 2019 Sep 02;99:106405 Authors: Kalilani L, Friesen D, Murray P Abstract OBJECTIVE: The objective of this study was to describe antiepileptic drug (AED) treatment patterns in patients with epilepsy, with and without psychiatric comorbidities. METHODS: This was a retrospective claims-based cohort study using Truven Health...
Related ArticlesQuality improvement in neurology: Epilepsy Quality Measurement Set 2017 update. Neurology. 2018 10 30;91(18):829-836 Authors: Patel AD, Baca C, Franklin G, Herman ST, Hughes I, Meunier L, Moura LMVR, Munger Clary H, Parker-McFadden B, Pugh MJ, Schultz RJ, Spanaki MV, Bennett A, Josephson SA PMID: 30282773 [PubMed - indexed for MEDLINE]
Related ArticlesLong-Term Follow-Up in Children With Focal Cortical Dysplasia IIId for Early Brain Injuries, Including Neuropathological Findings. Pediatr Neurol. 2018 11;88:40-47 Authors: Yan L, Yue-Shan P, Yunlin L, Yongling L, Zhichao W, Yuandong H Abstract BACKGROUND: Early cerebral injury has a close relationship with epilepsy and focal cortical dysplasia Ⅲd. We investigated children with focal cortical dysplasia Ⅲd who underwent surgery for epilepsy....
Related ArticlesA Comparison of Evoked and Non-evoked Functional Networks. Brain Topogr. 2019 05;32(3):405-417 Authors: Hebbink J, van Blooijs D, Huiskamp G, Leijten FSS, van Gils SA, Meijer HGE Abstract The growing interest in brain networks to study the brain's function in cognition and diseases has produced an increase in methods to extract these networks. Typically, each method yields a different network. Therefore, one may ask what the resulting...
Related ArticlesMEG Assessment of Expressive Language in Children Evaluated for Epilepsy Surgery. Brain Topogr. 2019 05;32(3):492-503 Authors: Foley E, Cross JH, Thai NJ, Walsh AR, Bill P, Furlong P, Wood AG, Cerquiglini A, Seri S Abstract Establishing language dominance is an important step in the presurgical evaluation of patients with refractory epilepsy. In the absence of a universally accepted gold-standard non-invasive method to determine language...
Related ArticlesCirculating high mobility group box-1 and toll-like receptor 4 expressions increase the risk and severity of epilepsy. Braz J Med Biol Res. 2019;52(7):e7374 Authors: Kan M, Song L, Zhang X, Zhang J, Fang P Abstract This study aimed to investigate the association of serum high-mobility group box-1 (HMGB1) and toll-like receptor 4 (TLR4) expressions with the risk of epilepsy as well as their correlations with disease severity and resistance...
Related ArticlesSubstantial Remission in Subacute Sclerosing Panencephalitis by Following the Ketogenic Diet: A Case Report. Cureus. 2019 Aug 25;11(8):e5485 Authors: Nathan J, Khedekar Kale D, Naik VD, Thakker F, Bailur S Abstract An eight-year-old boy presented with rhythmic myoclonic jerks that stretched back to the age of four years. He was diagnosed as having subacute sclerosing panencephalitis (SSPE). This is a progressive and almost uniformly fatal...
Related ArticlesTowards Successes in the Management of Nonconvulsive Status Epilepticus: Tracing the Detection-to-Needle Trajectories. J Clin Neurophysiol. 2019 Aug 29;: Authors: Baang HY, Swingle N, Sajja K, Madhavan D, Shostrom VK, Taraschenko O Abstract PURPOSE: Data on the timeliness of emergent medication delivery for nonconvulsive status epilepticus (NCSE) are currently lacking. METHODS: Retrospective chart reviews (between 2015 and 2018)...
Related ArticlesmiR-125a-5p alleviates dysfunction and inflammation of pentylenetetrazol-induced epilepsy through targeting calmodulin-dependent protein kinase IV (CAMK4). Curr Neurovasc Res. 2019 Sep 06;: Authors: Liu Q, Wang L, Yan G, Zhang W, Huan Z, Li J Abstract BACKGROUND: MicroRNAs (miRNA) are known as a key role in the etiology and treatment of epilepsy through controlling the expression of gene. However, miR-125a-5p in the epilepsy is little...
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