Δευτέρα 2 Σεπτεμβρίου 2019

ERα-mediated alterations in circ_0023642 and miR-490-5p signaling suppress bladder cancer invasion

Longxiang Wu, Mengda Zhang, Lin Qi, Xiongbing Zu, Yuan Li et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1827-3

The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer

Marina Kazantseva, Sunali Mehta, Ramona A. Eiholzer, Gregory Gimenez, Sara Bowie et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1861-1

Protopanaxadiol inhibits epithelial–mesenchymal transition of hepatocellular carcinoma by targeting STAT3 pathway

Lan Yang, Xue-ying Zhang, Kun Li, An-ping Li, Wen-dong Yang et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1733-8

Ferroportin downregulation promotes cell proliferation by modulating the Nrf2–miR-17-5p axis in multiple myeloma

Yuanyuan Kong, Liangning Hu, Kang Lu, Yingcong Wang, Yongsheng Xie et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1854-0

UPF1 regulates the malignant biological behaviors of glioblastoma cells via enhancing the stability of Linc-00313

Lianqi Shao, Qianru He, Yunhui Liu, Xiaobai Liu, Jian Zheng et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1845-1

Deletion of OSBPL2 in auditory cells increases cholesterol biosynthesis and drives reactive oxygen species production by inhibiting AMPK activity

Hongshun Wang, Changsong Lin, Jun Yao, Hairong Shi, Cui Zhang et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1858-9

Regulating autophagy facilitated therapeutic efficacy of the sonic Hedgehog pathway inhibition on lung adenocarcinoma through GLI2 suppression and ROS production

Jiajun Fan, Xuyao Zhang, Shaofei Wang, Wei Chen, Yubin Li et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1840-6

NudC-like protein 2 restrains centriole amplification by stabilizing HERC2

Min Li, Xiaoyang Xu, Jun Zhang, Min Liu, Wei Wang et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1843-3

Downregulation of eukaryotic translation initiation factor 3b inhibited proliferation and metastasis of gastric cancer

Fang Ma, Xue Li, Juchao Ren, Ruiting Guo, Yuwei Li et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1846-0

SIRT1-targeted miR-543 autophagy inhibition and epithelial–mesenchymal transition promotion in Helicobacter pylori CagA-associated gastric cancer

Yanyan Shi, Ziwei Yang, Ting Zhang, Lijuan Shen, Yuan Li et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1859-8

Inhibition of IRE1α RNase activity reduces NLRP3 inflammasome assembly and processing of pro-IL1β

Aaron Talty, Shane Deegan, Mila Ljujic, Katarzyna Mnich, Serika D. Naicker et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1847-z

Characterization of TNF-induced cell death in Drosophila reveals caspase- and JNK-dependent necrosis and its role in tumor suppression

Mingli Li, Shiyao Sun, Jessica Priest, Xiaolin Bi & Yun Fan
Cell Death & Disease 2019 10: 10.1038/s41419-019-1862-0

The POU4F2/Brn-3b transcription factor is required for the hypertrophic response to angiotensin II in the heart

Laura Mele, Lauren J. Maskell, Daniel J. Stuckey, James E. Clark, Richard J. Heads et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1848-y

Long noncoding RNA ABHD11-AS1 functions as a competing endogenous RNA to regulate papillary thyroid cancer progression by miR-199a-5p/SLC1A5 axis

Xi Zhuang, Houchao Tong, Yu Ding, Luyao Wu, Jingsheng Cai et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1850-4

Sirtuin 3-mediated pyruvate dehydrogenase activity determines brown adipocytes phenotype under high-salt conditions

Tong Wei, Gaojian Huang, Penghao Liu, Jing Gao, Chenglin Huang et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1834-4

mTOR direct crosstalk with STAT5 promotes de novo lipid synthesis and induces hepatocellular carcinoma

Ting Li, Jun Weng, Yue Zhang, Kangyan Liang, Gongbo Fu et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1828-2

Circular RNA PRKCI promotes glioma cell progression by inhibiting microRNA-545

Xuebang Zhang, Han Yang, Lihao Zhao, Gang Li & Yuxia Duan
Cell Death & Disease 2019 10: 10.1038/s41419-019-1863-z

MLP-deficient human pluripotent stem cell derived cardiomyocytes develop hypertrophic cardiomyopathy and heart failure phenotypes due to abnormal calcium handling

Xiaowei Li, Wen-Jing Lu, Ya’nan Li, Fujian Wu, Rui Bai et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1826-4

Increased clusterin levels after myocardial infarction is due to a defect in protein degradation systems activity

Annie Turkieh, Sina Porouchani, Olivia Beseme, Maggy Chwastyniak, Philippe Amouyel et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1857-x

Aurora-A/ERK1/2/mTOR axis promotes tumor progression in triple-negative breast cancer and dual-targeting Aurora-A/mTOR shows synthetic lethality

Wenfeng Zhang, Ding Xia, Zhangyun Li, Tao Zhou, Tingting Chen et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1855-z

The NEDD8-activating enzyme inhibitor MLN4924 sensitizes a TNFR1+ subgroup of multiple myeloma cells for TNF-induced cell death

Mohamed El-Mesery, Tina Rosenthal, Hilka Rauert-Wunderlich, Martin Schreder, Thorsten Stühmer et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1860-2

MCT1 relieves osimertinib-induced CRC suppression by promoting autophagy through the LKB1/AMPK signaling

Ping Jin, Jingwen Jiang, Na Xie, Li Zhou, Zhao Huang et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1844-2

Paeonol induces cytoprotective autophagy via blocking the Akt/mTOR pathway in ovarian cancer cells

Likun Gao, Zhi Wang, Danhua Lu, Jinling Huang, Jin Liu et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1849-x

Targeting HIBCH to reprogram valine metabolism for the treatment of colorectal cancer

Yunlong Shan, Yuan Gao, Wei Jin, Minmin Fan, Ying Wang et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1832-6

A mechanism for increased sensitivity of acute myeloid leukemia to mitotoxic drugs

Svetlana B. Panina, Natalia Baran, Fabio H. Brasil da Costa, Marina Konopleva & Natalia V. Kirienko
Cell Death & Disease 2019 10: 10.1038/s41419-019-1851-3

SOCS5 inhibition induces autophagy to impair metastasis in hepatocellular carcinoma cells via the PI3K/Akt/mTOR pathway

Mao Zhang, Shihai Liu, Mei-Sze Chua, Haoran Li, Dingan Luo et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1856-y

Excess hepsin proteolytic activity limits oncogenic signaling and induces ER stress and autophagy in prostate cancer cells

Ramona Willbold, Katharina Wirth, Thomas Martini, Holger Sültmann, Christian Bolenz et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1830-8

The Hippo effector TAZ promotes cancer stemness by transcriptional activation of SOX2 in head neck squamous cell carcinoma

Jin Li, Zhongwu Li, Yaping Wu, Yanling Wang, Dongmiao Wang et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1838-0

CDK7 inhibitor THZ1 inhibits MCL1 synthesis and drives cholangiocarcinoma apoptosis in combination with BCL2/BCL-XL inhibitor ABT-263

Tianlu Huang, Xiwei Ding, Guifang Xu, Gang Chen, Yu Cao et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1831-7

The transcriptional landscape of lncRNAs reveals the oncogenic function of LINC00511 in ER-negative breast cancer

Jian Zhang, Shiyao Sui, Hao Wu, Jinfeng Zhang, Xingda Zhang et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1835-3

Differentiation of human adipose-derived stem cells into neuron/motoneuron-like cells for cell replacement therapy of spinal cord injury

Shane Gao, Xuanxuan Guo, Simeng Zhao, Yinpeng Jin, Fei Zhou et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1772-1

Folate can promote the methionine-dependent reprogramming of glioblastoma cells towards pluripotency

Racha Zgheib, Shyue-Fang Battaglia-Hsu, Sébastien Hergalant, Maelle Quéré, Jean-Marc Alberto et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1836-2

The synergistic effects of oxaliplatin and piperlongumine on colorectal cancer are mediated by oxidative stress

WeiQian Chen, WeiShuai Lian, YiFeng Yuan & MaoQuan Li
Cell Death & Disease 2019 10: 10.1038/s41419-019-1824-6

PUM1 knockdown prevents tumor progression by activating the PERK/eIF2/ATF4 signaling pathway in pancreatic adenocarcinoma cells

Haisu Dai, Kaicheng Shen, Yishi Yang, Xingxing Su, Yuandeng Luo et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1839-z

CXCR2 expression on granulocyte and macrophage progenitors under tumor conditions contributes to mo-MDSC generation via SAP18/ERK/STAT3

Xiaoqing Han, Huifang Shi, Yingying Sun, Chao Shang, Tao Luan et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1837-1

LncRNA NR_003923 promotes cell proliferation, migration, fibrosis, and autophagy via the miR-760/miR-215-3p/IL22RA1 axis in human Tenon’s capsule fibroblasts

Yang Zhao, Feng Zhang, Zheng Pan, Haomin Luo, Ke Liu et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1829-1

Autophagy inhibition-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis

Charlotte Hill, Juanjuan Li, Dian Liu, Franco Conforti, Christopher J. Brereton et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1820-x

Avenanthramide A triggers potent ROS-mediated anti-tumor effects in colorectal cancer by directly targeting DDX3

Rong Fu, Peng Yang, Zongwei Li, Wen Liu, Sajid Amin et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1825-5

O-cyclic phytosphingosine-1-phosphate stimulates HIF1α-dependent glycolytic reprogramming to enhance the therapeutic potential of mesenchymal stem cells

Hyun Jik Lee, Young Hyun Jung, Gee Euhn Choi, Jun Sung Kim, Chang Woo Chae et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1823-7

Long noncoding RNA DANCR regulates proliferation and migration by epigenetically silencing FBP1 in tumorigenesis of cholangiocarcinoma

Ni Wang, Chongguo Zhang, Wulin Wang, Jie Liu, Yang Yu et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1810-z

Inhibition of ZIP4 reverses epithelial-to-mesenchymal transition and enhances the radiosensitivity in human nasopharyngeal carcinoma cells

Qi Zeng, Yi-min Liu, Jun Liu, Jian Han, Jian-xin Guo et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1807-7

C-Jun drives melanoma progression in PTEN wild type melanoma cells

Melanie Kappelmann-Fenzl, Claudia Gebhard, Alexander O. Matthies, Silke Kuphal, Michael Rehli et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1821-9

DPP8/9 inhibitors are universal activators of functional NLRP1 alleles

Kuo Gai, Marian C. Okondo, Sahana D. Rao, Ashley J. Chui, Daniel P. Ball et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1817-5

TOPK inhibits autophagy by phosphorylating ULK1 and promotes glioma resistance to TMZ

Hui Lu, Juanjuan Xiao, Changshu Ke, Xiaofang Ni, Ruijuan Xiu et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1805-9

Inhibition of transmembrane TNF-α shedding by a specific antibody protects against septic shock

Chenxi Li, Haiyan Gu, Mingxia Yu, Peng Yang, Meng Zhang et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1808-6

Asymmetrical methyltransferase PRMT3 regulates human mesenchymal stem cell osteogenesis via miR-3648

Zhang Min, Liu Xiaomeng, Li Zheng, Du Yangge, Liu Xuejiao et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1815-7

miR-425 deficiency promotes necroptosis and dopaminergic neurodegeneration in Parkinson’s disease

Yong-Bo Hu, Yong-Fang Zhang, Hao Wang, Ru-Jing Ren, Hai-Lun Cui et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1809-5

Exogenous WNT5A and WNT11 proteins rescue CITED2 dysfunction in mouse embryonic stem cells and zebrafish morphants

João M. A. Santos, Leonardo Mendes-Silva, Vanessa Afonso, Gil Martins, Rui S. R. Machado et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1816-6

Macrophages exposed to HIV viral protein disrupt lung epithelial cell integrity and mitochondrial bioenergetics via exosomal microRNA shuttling

Zhihong Yuan, Jessica R. Petree, F. Eun-Hyung Lee, Xian Fan, Khalid Salaita et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1803-y

Extracorporeal photochemotherapy induces bona fide immunogenic cell death

Kazuki Tatsuno, Takahiro Yamazaki, Douglas Hanlon, Patrick Han, Eve Robinson et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1819-3

circHECTD1 facilitates glutaminolysis to promote gastric cancer progression by targeting miR-1256 and activating β-catenin/c-Myc signaling

Juan Cai, Zhiqiang Chen, Jinguo Wang, Junfeng Wang, Xianjun Chen et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1814-8

Site-specific phosphorylation of Fbxw7 by Cdk5/p25 and its resulting decreased stability are linked to glutamate-induced excitotoxicity

Yeon Uk Ko, Chiho Kim, Juhyung Lee, Dana Kim, Yoonkyung Kim et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1818-4

The effect of fluoxetine on astrocyte autophagy flux and injured mitochondria clearance in a mouse model of depression

Xiaodong Shu, Yiming Sun, Xiyang Sun, Yuanzhang Zhou, Yaqi Bian et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1813-9

CORRECTION

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Correction: ERβ promotes Aβ degradation via the modulation of autophagy

Yong Wei, Jiawei Zhou, Jun Wu & Jian Huang
Cell Death & Disease 2019 10: 10.1038/s41419-019-1867-8

Correction: Mechanism of Snhg8/miR-384/Hoxa13/FAM3A axis regulating neuronal apoptosis in ischemic mice model

Jie Liu, Ping An, Yixue Xue, Dongfang Che, Xiaobai Liu et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1865-x

Author Correction: Linc-DYNC2H1-4 promotes EMT and CSC phenotypes by acting as a sponge of miR-145 in pancreatic cancer cells

Yuran Gao, Zhicheng Zhang, Kai Li, Liying Gong, Qingzhu Yang et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1852-2

Retraction Note: Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation

Tahereh Javaheri, Zahra Kazemi, Jan Pencik, Ha T. T. Pham, Maximilian Kauer et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1853-1

Correction: H19 lncRNA alters methylation and expression of Hnf4α in the liver of metformin-exposed fetuses

Jie Deng, Martin Mueller, Tingting Geng, Yuanyuan Shen, Ya Liu et al.
Cell Death & Disease 2019 10: 10.1038/s41419-019-1812-x

REVIEW ARTICLE

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Fasting and rapamycin: diabetes versus benevolent glucose intolerance

Mikhail V. Blagosklonny
Cell Death & Disease 2019 10: 10.1038/s41419-019-1822-8
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