Methicillin-resistant Staphylococcus aureus (MRSA) is one of a medically important Gram-positive bacteria, which can be harboured majorly in the nasal cavity. Risk of consequent infection in a person colonized wi...
Thu Sep 05, 2019 03:00
Summary Cancer treatment is challenging, mainly due to high levels of drug toxicity and the resistance of tumours to chemotherapy. Hydroxamic acid derivatives have recently aroused attention due to their potential to treat malignancies. In the present study, we sought to investigate the anticancer effects of a new series of synthetic acetohydroxamates. The in vitro cytotoxic and antiproliferative effects of 11 synthetic acetohydroxamates were evaluated against the melanoma cell...
Fri Sep 06, 2019 03:00
Abstract Objectives The purpose of the study is to investigate feasibility of early activation after cochlear implantation by evaluating long term impedance change and speech perception. Methods We designed a case‐control study including 40 patients who underwent cochlear implantation surgeries. Between July 2015 and December 2016, we prospectively enrolled 20 subjects for early activation (within 24 hours after cochlear implantation). On the other hand, from November 2013 to July 2015,...
Thu Sep 05, 2019 19:57
Chronic Respiratory Disease, Volume 16, Issue , January-December 2019. The endurance shuttle walk test (ESWT) is frequently used as an outcome measure for pulmonary rehabilitation (PR). The minimal important difference (MID) for the ESWT after a course of rehabilitation has not been conclusively confirmed in the literature. The aim was to establish the MID for the ESWT following the 6-week PR programme in patients with chronic obstructive pulmonary disease (COPD). Following the completion of the...
Fri Sep 06, 2019 10:40
Publication date: Available online 5 September 2019Source: American Journal of Infection ControlAuthor(s): Carole Lemarié, Clément Legeay, Achille Kouatchet, Rafael Mahieu, Sigismond Lasocki, Pamela Holecska, Laura Onillon, Maxime Corre, Marie Kempf, Matthieu EveillardWe report a high prevalence (28%) of sink drains contaminated with carbapenemase-producing Enterobacteriaceae (CPE) in 4 intensive care units with a history of CPE carriage in hospitalized patients within the previous 5 years, but apart...
Fri Sep 06, 2019 13:47
Publication date: Available online 5 September 2019Source: Computer Speech & LanguageAuthor(s): Jean-François Bonastre, Tomi Kinnunen, Anthony Larcher, Junichi Yamagishi
Fri Sep 06, 2019 15:06
Background: Compensatory deglutition strategies such as change of posture, swallowing maneuvers, and sensory stimulation have been used by speech-language pathologists (SLPs) to alter oral and pharyngeal biodynamics. Objective: To analyze the immediate effect of the dry swallowing maneuver in patients with neurogenic dysphagia. Methodology: The participants were 11 individuals with neurogenic dysphagia who underwent videofluoroscopic swallowing study while performing dry swallow maneuvers for different...
Fri Sep 06, 2019 13:41
Related Articles[Dysphagia in cervical spine diseases]. HNO. 2019 Sep 04;: Authors: Riepl R, Hoffmann TK, Goldberg-Bockhorn E, Richter P, Reiter R Abstract Dysphagia is a common symptom and can be indicative of a variety of heterogeneous diseases. "Classical" diseases of the head and neck region, such as acute tonsillitis, peritonsillar abscesses, diverticula, and benign or malignant tumors are common causes of dysphagia. However, it can also occur in...
Fri Sep 06, 2019 17:37
Related Articles[Incomplete partition type III revisited-long-term results following cochlear implant. German version]. HNO. 2019 Sep 04;: Authors: Alballaa A, Aschendorff A, Arndt S, Hildenbrand T, Becker C, Hassepass F, Laszig R, Beck R, Speck I, Wesarg T, Ketterer MC Abstract BACKGROUND: Incomplete partition type III (IP III) is defined by a missing lamina cribrosa between the cochlea and the internal auditory canal (IAC). Cochlear implantation (CI)...
Fri Sep 06, 2019 17:37
Related ArticlesElectric field simulations for transcranial brain stimulation using FEM: an efficient implementation and error analysis. J Neural Eng. 2019 Sep 05;: Authors: Saturnino GB, Madsen KH, Thielscher A Abstract OBJECTIVE: Transcranial magnetic stimulation (TMS) and transcranial electric stimulation (TES) modulate brain activity non-invasively by generating electric fields either by electromagnetic induction or by injecting currents via skin...
Fri Sep 06, 2019 17:37
1975–2019 Sonja Luehrmann, anthropologist and historian, passed away on August 24, 2019. Luehrmann began her studies in Germany. Early on, she focused on topics that would become central to her wide-ranging, prodigious, brilliant, and yet all-too-brief scholarly career, especially the politics of religious and cultural difference as well as the contested and shifting meanings of history. While Luehrmann’s specific topics would change, from indigeneity to internet matchmaking to secularism, prayer,...
Fri Sep 06, 2019 17:58
Abstract Background Tooth brushing with fluoride toothpaste is a key recommendation in evidence-based guidelines for caries prevention. Parents generally have sufficient knowledge to practice tooth brushing for their child, yet many experience barriers to actually implement the behaviour. Common barriers are associated with difficult child behaviour, stress, poor family organisation and management of routines. These underlying determinants...
Fri Sep 06, 2019 03:00
Abstract Background The purpose of this study was to assess the salivary cortisol and salivary alpha-amylase levels in children aged between 6 and 9 years, 3 months and 1 year after the successful completion of dental treatment through either pharmacological or non-pharmacological behavior management techniques. Methods A total of 1567 patients...
Fri Sep 06, 2019 03:00
Related ArticlesC-Terminal HSP90 Inhibitors Block the HIF-1 Hypoxic Response by Degrading HIF-1α through the Oxygen-Dependent Degradation Pathway. Cell Physiol Biochem. 2019;53(3):480-495 Authors: Kataria N, Martinez CA, Kerr B, Zaiter SS, Morgan M, McAlpine SR, Cook KM Abstract BACKGROUND/AIMS: Hypoxia Inducible Factor-1α (HIF-1α) is involved in cancer progression and is stabilized by the chaperone HSP90 (Heat Shock Protein 90), preventing degradation....
Fri Sep 06, 2019 18:13
Related ArticlesStorage Primes Erythrocytes for Necroptosis and Clearance. Cell Physiol Biochem. 2019;53(3):496-507 Authors: McCaig WD, Hodges AL, Deragon MA, Haluska RJ, Bandyopadhyay S, Ratner AJ, Spitalnik SL, Hod EA, LaRocca TJ Abstract BACKGROUND/AIMS: Like nucleated cells, erythrocytes (red blood cells, RBCs) are capable of executing programmed cell death pathways. RBCs undergo necroptosis in response to CD59-specific pore-forming toxins (PFTs)....
Fri Sep 06, 2019 18:13
Objectives: The main objective of this study is to determine whether chronic sound deprivation leads to poorer speech discrimination in humans. Design: We reviewed the audiologic profile of 240 patients presenting normal and symmetrical bone conduction thresholds bilaterally, associated with either an acute or chronic unilateral conductive hearing loss of different etiologies. Results: Patients with chronic conductive impairment and a moderate, to moderately severe, hearing loss had...
Thu Sep 05, 2019 03:00
Objective To explore the application value of postlabeling delay (PLD) in 3D pseudocontinuous arterial spin–labeled (3D-pcASL) perfusion imaging in normal children and to find the optimal PLD values for children at each age group. Methods Five groups of children, with 50 patients in each group, who underwent routine magnetic resonance imaging scans with normal results were included. The patients were stratified according to the following ages: younger than 1 month, more than 1 month to 6...
Thu Sep 05, 2019 03:00
Purpose This study aimed to describe the computed tomographic (CT) findings of gastric hepatoid adenocarcinoma (GHA) and determine features distinguishing it from gastric adenocarcinoma (GA). Methods Computed tomographic images of pathologically verified GHA (n = 11) and GA (n = 38) were retrospectively reviewed. α-Fetoprotein (AFP), carcinoembryonic antigen (CEA), and CT findings were assessed in our study. Computed tomographic findings included the location, distribution, growth pattern,...
Thu Sep 05, 2019 03:00
Objectives The aims of this study were to compare the difference of computed tomography (CT) features between intrahepatic cholangiocarcinomas (ICCs) with and without lymph node metastasis (LNM) and to construct a nomogram to predict LNM and overall survival preoperatively. Methods Clinicopathological and contrast-enhanced CT features of 63 patients with ICC were analyzed. Multivariate logistic regression analysis was performed to construct a nomogram to predict LNM preoperatively. Survival...
Thu Sep 05, 2019 03:00
Purpose The aim of the study was to refine and validate the NeuroImaging Radiological Interpretation System (NIRIS), which was developed to predict management and clinical outcome based on noncontrast head computerized tomography findings in patients suspected of acute traumatic brain injury (TBI). Methods We assessed the performance of the NIRIS score in a prospective, single-center cohort of patients suspected of TBI (n = 648) and compared the performance of NIRIS with that of the Marshall...
Thu Sep 05, 2019 03:00
Objective The objective of this study was to evaluate a prototype, ultrahigh-resolution computed tomography offering higher reconstruction matrix (1024 × 1024) and spatial resolution (0.15 mm) for chest imaging. Methods Higher (1024) matrix reconstruction enabled by ultrahigh-resolution computed tomography scanner (128-detector rows; detector width, 0.25 mm; spatial resolution, 0.15 mm) was compared with conventional (512) reconstruction with image quality grading on a Likert scale (1, excellent;...
Thu Sep 05, 2019 03:00
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These articles are published with open access at Springerlink.com.
Fri Sep 06, 2019 03:00
Sickness presenteeism among healthcare professionals can compromise patient safety. To better understand what motivates this phenomenon, especially among trainees, the authors investigated attitudes of medical...
Thu Sep 05, 2019 03:00
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