Cells, Vol. 8, Pages 813: Cell–Cell Adhesion and Myosin Activity Regulate Cortical Actin Assembly in Mammary Gland Epithelium on Concaved Surface Cells doi: 10.3390/cells8080813 Authors: Wei-Hung Jung Khalid Elawad Sung Hoon Kang Yun Chen It has been demonstrated that geometry can affect cell behaviors. Though curvature-sensitive proteins at the nanoscale are studied, it is unclear how cells sense curvature at the cellular and multicellular levels. To characterize and determine...
Cells, Vol. 8, Pages 814: Interplay between Phosphatases and the Anaphase-Promoting Complex/Cyclosome in Mitosis Cells doi: 10.3390/cells8080814 Authors: Meghna Kataria Hiroyuki Yamano Accurate division of cells into two daughters is a process that is vital to propagation of life. Protein phosphorylation and selective degradation have emerged as two important mechanisms safeguarding the delicate choreography of mitosis. Protein phosphatases catalyze dephosphorylation of thousands...
IJMS, Vol. 20, Pages 3780: Formation Mechanism of Ion Channel in Channelrhodopsin-2: Molecular Dynamics Simulation and Steering Molecular Dynamics Simulations International Journal of Molecular Sciences doi: 10.3390/ijms20153780 Authors: Ting Yang Wenying Zhang Jie Cheng Yanhong Nie Qi Xin Shuai Yuan Yusheng Dou Channelrhodopsin-2 (ChR2) is a light-activated and non-selective cationic channel protein that can be easily expressed in specific neurons to control neuronal...
IJMS, Vol. 20, Pages 3781: Effect of the Hydrophilic-Hydrophobic Balance of Antigen-Loaded Peptide Nanofibers on Their Cellular Uptake, Cellular Toxicity, and Immune Stimulatory Properties International Journal of Molecular Sciences doi: 10.3390/ijms20153781 Authors: Tomonori Waku Saki Nishigaki Yuichi Kitagawa Sayaka Koeda Kazufumi Kawabata Shigeru Kunugi Akio Kobori Naoki Tanaka Recently, nanofibers (NFs) formed from antigenic peptides conjugated to β-sheet-forming...
IJMS, Vol. 20, Pages 3782: Study of the Mechanism Underlying the Onset of Diabetic Xeroderma Focusing on an Aquaporin-3 in a Streptozotocin-Induced Diabetic Mouse Model International Journal of Molecular Sciences doi: 10.3390/ijms20153782 Authors: Nobutomo Ikarashi Nanaho Mizukami Risako Kon Miho Kaneko Ryogo Uchino Izumi Fujisawa Natsuko Fukuda Hiroyasu Sakai Junzo Kamei Xeroderma is a frequent complication in diabetic patients. In this study, we investigated...
Antibodies, Vol. 8, Pages 43: Design and Production of Bispecific Antibodies Antibodies doi: 10.3390/antib8030043 Authors: Qiong Wang Yiqun Chen Jaeyoung Park Xiao Liu Yifeng Hu Tiexin Wang Kevin McFarland Michael J. Betenbaugh With the current biotherapeutic market dominated by antibody molecules, bispecific antibodies represent a key component of the next-generation of antibody therapy. Bispecific antibodies can target two different antigens at the same time, such...
Social Sciences, Vol. 8, Pages 231: Trends in International PISA Scores over Time: Which Countries Are Actually Improving? Social Sciences doi: 10.3390/socsci8080231 Authors: Kristie J. Rowley Shelby M. McNeill Mikaela J. Dufur Chrisse Edmunds Jonathan A. Jarvis Many countries attempt to increase their Program for International Student Assessment (PISA) rankings and scores over time. However, despite providing a more accurate assessment of the achievement-based improvements...
Nutrients, Vol. 11, Pages 1789: Self-Report Dieters: Who Are They? Nutrients doi: 10.3390/nu11081789 Authors: Laura Sares-Jäske Paul Knekt Satu Männistö Olavi Lindfors Markku Heliövaara Dieting attempts have become popular worldwide. Dieting, however, seems to have both positive and negative health-related consequences. So far, only a few studies have focused on the determinants of dieting in detail. This study explores the association between self-report dieting attempts...
Nutrients, Vol. 11, Pages 1790: Early Probiotic Supplementation and the Risk of Celiac Disease in Children at Genetic Risk Nutrients doi: 10.3390/nu11081790 Authors: Ulla Uusitalo Carin Andren Aronsson Xiang Liu Kalle Kurppa Jimin Yang Edwin Liu Jennifer Skidmore Christiane Winkler Marian Rewers William Hagopian Jin-Xiong She Jorma Toppari Anette-G. Ziegler Beena Akolkar Jill Norris Suvi Virtanen Jeffrey Krischer Daniel Agardh on behalf...
Sci. Pharm., Vol. 87, Pages 18: Antinociceptive Effect of Single Components Isolated from Agrimonia pilosa Ledeb. Extract Scientia Pharmaceutica doi: 10.3390/scipharm87030018 Authors: Jing Hui Feng Hee Jung Lee Set Byeol Kim Jeon Sub Jung Soon Sung Lim Hong Won Suh Agrimonia pilosa Ledeb. produces an antinociceptive effect in ICR mice in both chemically induced and thermal pain models. In the present study, we examined the antinociceptive effects of single components isolated...
Molecules, Vol. 24, Pages 2824: Effect of Preheating Treatment before Defatting on the Flavor Quality of Skim Milk Molecules doi: 10.3390/molecules24152824 Authors: Lingjun Tong Huaxi Yi Jing Wang Minghui Pan Xuelu Chi Haining Hao Nasi Ai Skim milk has a poor flavor due to the lack of fat. Finding ways to improve the flavor quality of skim milk has attracted the attention of more and more researchers. The purpose of this study was to create a skim milk product with...
Water, Vol. 11, Pages 1605: Groundwater as a Source of Drinking Water in Southeast Asia and the Pacific: A Multi-Country Review of Current Reliance and Resource Concerns Water doi: 10.3390/w11081605 Authors: Naomi Carrard Tim Foster Juliet Willetts Groundwater is widely acknowledged to be an important source of drinking water in low-income regions, and it, therefore, plays a critical role in the realization of the human right to water. However, the proportion of households using...
Water, Vol. 11, Pages 1604: Hotel Water Demand: The Impact of Changing from Linear to Increasing Block Rates Water doi: 10.3390/w11081604 Authors: Bartolomé Deyà-Tortella Celso Garcia William Nilsson Dolores Tirado Water is a key aspect for any tourist destination. The pressure of tourism on water resources, and specifically by the hotel sector on islands and coastal areas, threatens the sustainability of the resource and, ultimately, of the destination. Several international...
Water, Vol. 11, Pages 1603: Hydrologic Response in an Urban Watershed as Affected by Climate and Land-Use Change Water doi: 10.3390/w11081603 Authors: Mohamed Aboelnour Margaret W. Gitau Bernard A. Engel The change in both streamflow and baseflow in urban catchments has received significant attention in recent decades as a result of their drastic variability. In this research, effects of climate variation and dynamics of land use are measured separately and in combination with...
IJERPH, Vol. 16, Pages 2762: The Predictive Value of Emotional Intelligence for Internet Gaming Disorder: A 1-Year Longitudinal Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16152762 Authors: Della L. Dang Meng Xuan Zhang Karlas Kin-hei Leong Anise M. S. Wu This one-year longitudinal study examined trait emotional intelligence as a predictor of Internet gaming disorder (IGD). To date, only cross-sectional research has been conducted...
IJERPH, Vol. 16, Pages 2763: Environmental Influences on Food Behaviour International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16152763 Authors: Catherine Paquet The ubiquitous presence of food cues in our modern environment is believed to contribute to the rising trends in overconsumption and associated obesity observed over the last few decades [...]
Metabolites, Vol. 9, Pages 162: rMSIKeyIon: An Ion Filtering R Package for Untargeted Analysis of Metabolomic LDI-MS Images Metabolites doi: 10.3390/metabo9080162 Authors: Esteban del Castillo Lluc Sementé Sònia Torres Pere Ràfols Noelia Ramírez Manuela Martins-Green Manel Santafe Xavier Correig Many MALDI-MS imaging experiments make a case versus control studies of different tissue regions in order to highlight significant compounds affected by the variables of...
Nutrients, Vol. 11, Pages 1788: Assessing and Managing the Metabolic Syndrome in Children and Adolescents Nutrients doi: 10.3390/nu11081788 Authors: Mark D. DeBoer The metabolic syndrome (MetS) is a group of cardiovascular risk factors that are associated with insulin resistance and are driven by underlying factors, including visceral obesity, systemic inflammation, and cellular dysfunction. These risks increasingly begin in childhood and adolescence and are associated with a high likelihood...
JCM, Vol. 8, Pages 1155: Effect of Iron Supplementation on the Outcome of Non-Progressive Pulmonary Mycobacterium tuberculosis Infection Journal of Clinical Medicine doi: 10.3390/jcm8081155 Authors: Afsal Kolloli Pooja Singh G. Marcela Rodriguez Selvakumar Subbian The human response to Mycobacterium tuberculosis (Mtb) infection is affected by the availability of iron (Fe), which is necessary for proper immune cell function and is essential for the growth and virulence of bacteria....
JCM, Vol. 8, Pages 1156: Outpatient Readmission in Rheumatology: A Machine Learning Predictive Model of Patient’s Return to the Clinic Journal of Clinical Medicine doi: 10.3390/jcm8081156 Authors: Alfredo Madrid-García Judit Font-Urgelles Mario Vega-Barbas Leticia León-Mateos Dalifer Dayanira Freites Cristina Jesus Lajas Esperanza Pato Juan Angel Jover Benjamín Fernández-Gutiérrez Lydia Abásolo-Alcazar Luis Rodríguez-Rodríguez Our objective is to develop...
IJMS, Vol. 20, Pages 3779: JA-Induced Endocytosis of AtRGS1 Is Involved in G-Protein Mediated JA Responses International Journal of Molecular Sciences doi: 10.3390/ijms20153779 Authors: Li Li Bodan Su Xueying Qi Xi Zhang Susheng Song Xiaoyi Shan Arabidopsis heterotrimeric G proteins regulate diverse plant growth and defense processes by coupling to 7TM AtRGS1 proteins. Although G protein mutants display alterations in response to multiple plant hormones, the underlying...
Cells, Vol. 8, Pages 812: Molecular Mechanisms Associated with ROR1-Mediated Drug Resistance: Crosstalk with Hippo-YAP/TAZ and BMI-1 Pathways Cells doi: 10.3390/cells8080812 Authors: Hanna Karvonen Harlan Barker Laura Kaleva Wilhelmiina Niininen Daniela Ungureanu Signaling via the Wnt-related receptor tyrosine kinase-like orphan receptor 1 (ROR1) triggers tumorigenic features associated with cancer stem cells (CSCs) and epithelial–mesenchymal transition (EMT), while...
Antioxidants, Vol. 8, Pages 268: Role of Selenium and Selenoproteins in Male Reproductive Function: A Review of Past and Present Evidences Antioxidants doi: 10.3390/antiox8080268 Authors: Izhar Hyder Qazi Christiana Angel Haoxuan Yang Evangelos Zoidis Bo Pan Zhenzheng Wu Zhang Ming Chang-Jun Zeng Qingyong Meng Hongbing Han Guangbin Zhou Selenium (Se) is an important trace mineral having many essential roles at the cellular and organismal levels in animal...
Antioxidants, Vol. 8, Pages 267: Hepatoprotection of Mentha aquatica L., Lavandula dentata L. and Leonurus cardiaca L. Antioxidants doi: 10.3390/antiox8080267 Authors: Olívia R. Pereira Rocio I. R. Macias Maria R. M. Domingues Jose J. G. Marin Susana M. Cardoso The phenolic composition of hydroethanolic extracts of Mentha aquatica L., Lavandula dentata L. and Leonurus cardiaca L., obtained from plants grown under organic cultivation, was determined and their hepatoprotective...
Molecules, Vol. 24, Pages 2823: Analysis of the Carry-Over of Ochratoxin A from Feed to Milk, Blood, Urine, and Different Tissues of Dairy Cows Based on the Establishment of a Reliable LC-MS/MS Method Molecules doi: 10.3390/molecules24152823 Authors: Zhiqi Zhang Zhichen Fan Dongxia Nie Zhihui Zhao Zheng Han A rapid and reliable liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed for simultaneous determination of ochratoxin A (OTA) and its metabolite...
IJERPH, Vol. 16, Pages 2761: Dynamic Anemia Status from Infancy to Preschool-Age: Evidence from Rural China International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16152761 Authors: Lei Wang Mengjie Li Sarah-Eve Dill Yiwei Hu Scott Rozelle Anemia is a serious nutritional deficiency among infants and toddlers in rural China. However, it is unclear how the anemia status changes among China’s rural children as they age. This study investigates...
Nanomaterials, Vol. 9, Pages 1108: Multimaterial 3D Printing for Arbitrary Distribution with Nanoscale Resolution Nanomaterials doi: 10.3390/nano9081108 Authors: Fengqiang Zhang Changhai Li Zhenlong Wang Jia Zhang Yukui Wang At the core of additive manufacturing (3D printing) is the ability to rapidly print with multiple materials for arbitrary distribution with high resolution, which can remove challenges and limits of traditional assembly and enable us to make increasingly...
Atmosphere, Vol. 10, Pages 446: Comparison of Columnar, Surface, and UAS Profiles of Absorbing Aerosol Optical Depth and Single-Scattering Albedo in South-East Poland Atmosphere doi: 10.3390/atmos10080446 Authors: Michał T. Chiliński Krzysztof M. Markowicz Olga Zawadzka Iwona S. Stachlewska Justyna Lisok Przemysław Makuch The impact of absorbing aerosols on climate is complex, with their potential positive or negative forcing, depending on many factors, including their...
Foods, Vol. 8, Pages 312: Identification of a Lactic Acid Bacteria to Degrade Biogenic Amines in Chinese Rice Wine and Its Enzymatic Mechanism Foods doi: 10.3390/foods8080312 Authors: Tianjiao Niu Xing Li Yongjie Guo Ying Ma A L. plantarum, CAU 3823, which can degrade 40% of biogenic amines (BAs) content in Chinese rice wine (CRW) at the end of post-fermentation, was selected and characterized in this work. It would be an optimal choice to add 106 cfu/mL of selected strain into...
Pharmaceutics, Vol. 11, Pages 386: Physico-Chemical and Biological Evaluation of PLCL/SF Nanofibers Loaded with Oregano Essential Oil Pharmaceutics doi: 10.3390/pharmaceutics11080386 Authors: Atta ur Rehman Khan Muhammad Nadeem M. Aqeel Bhutto Fan Yu Xianrui Xie Hany El-Hamshary Ayman El-Faham Usama A. Ibrahim Xiumei Mo Essential oils are complex volatile compounds, extracted from specific plant species, with promising therapeutic potentials. However, their volatile...
Pharmaceutics, Vol. 11, Pages 383: Investigation of Dissolution Mechanism and Release Kinetics of Poorly Water-Soluble Tadalafil from Amorphous Solid Dispersions Prepared by Various Methods Pharmaceutics doi: 10.3390/pharmaceutics11080383 Authors: Tereza Školáková Michaela Slámová Andrea Školáková Alena Kadeřábková Jan Patera Petr Zámostný The aims of this study were to investigate how the release of tadalafil is influenced by two grades of polyvinylpyrrolidone (Kollidon®...
Pharmaceutics, Vol. 11, Pages 387: Sustained Release of Minor-Groove-Binding Antibiotic Netropsin from Calcium-Coated Groove-Rich DNA Particles Pharmaceutics doi: 10.3390/pharmaceutics11080387 Authors: Hyunsu Jeon Hyangsu Nam Jong Bum Lee Control of the release properties of drugs has been considered a key factor in the development of drug delivery systems (DDSs). However, drug delivery has limitations including cytotoxicity, low loading efficiency, and burst release. To overcome...
Nutrients, Vol. 11, Pages 1787: Dietary Micronutrients Intake Status among Chinese Elderly People Living at Home: Data from CNNHS 2010–2012 Nutrients doi: 10.3390/nu11081787 Authors: Zhen Liu Liyun Zhao Qingqing Man Jingzhong Wang Wenhua Zhao Jian Zhang The aim of this study was to examine the status of usual dietary micronutrient intakes among Chinese elderly living at home. The data was based on China National Nutrition and Health Survey (CNNHS) 2010–2012....
Water, Vol. 11, Pages 1602: Impact of Climate Change and Land-Use on the Propagation from Meteorological Drought to Hydrological Drought in the Eastern Qilian Mountains Water doi: 10.3390/w11081602 Authors: Junju Zhou Qiaoqiao Li Lanying Wang Li Lei Meihua Huang Juan Xiang Wei Feng Yaru Zhao Dongxiang Xue Chunfang Liu Wei Wei Guofeng Zhu As one of the most destructive and costly natural disasters, drought has far-reaching negative effects on agriculture,...
Water, Vol. 11, Pages 1601: Assessing Surface Sediment Contamination by PBDE in a Recharge Point of Guarani Aquifer in Ribeirão Preto, Brazil Water doi: 10.3390/w11081601 Authors: Raissa S. Ferrari Alecsandra O. de Souza Daniel L. R. Annunciação Fernando F. Sodré Daniel J. Dorta Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in several products, although they can act as neurotoxic, hepatotoxic and endocrine disruptors in organisms. In Brazil, their levels...
Plants, Vol. 8, Pages 263: Transcriptome Analysis of Young Ovaries Reveals Candidate Genes Involved in Gamete Formation in Lantana camara Plants doi: 10.3390/plants8080263 Authors: Ze Peng Krishna Bhattarai Saroj Parajuli Zhe Cao Zhanao Deng Lantana (Lantana camara L., Verbenaceae) is an important ornamental crop, yet can be a highly invasive species. The formation of unreduced female gametes (UFGs) is a major factor contributing to its invasiveness and has severely hindered...
IJMS, Vol. 20, Pages 3778: Ovarian Expression of Adipokines in Polycystic Ovary Syndrome: A Role for Chemerin, Omentin, and Apelin in Follicular Growth Arrest and Ovulatory Dysfunction? International Journal of Molecular Sciences doi: 10.3390/ijms20153778 Authors: Alice Bongrani Namya Mellouk Christelle Rame Marion Cornuau Fabrice Guérif Pascal Froment Joëlle Dupont Adipokines are a potential link between reproduction and energy metabolism and could partly explain some...
Molecules, Vol. 24, Pages 2821: Broad-Spectrum Antiviral Natural Products from the Marine-Derived Penicillium sp. IMB17-046 Molecules doi: 10.3390/molecules24152821 Authors: Jiao Li Yujia Wang Xiaomeng Hao Shasha Li Jia Jia Yan Guan Zonggen Peng Hongkai Bi Chunling Xiao Shan Cen Maoluo Gan A new pyrazine derivative, trypilepyrazinol (1), a new α-pyrone polyketide, (+)-neocitreoviridin (2), and a new ergostane analogue, 3β-hydroxyergosta-8,14,24(28)-trien-7-one...
Molecules, Vol. 24, Pages 2822: Effects of Halogen, Chalcogen, Pnicogen, and Tetrel Bonds on IR and NMR Spectra Molecules doi: 10.3390/molecules24152822 Authors: Jia Lu Steve Scheiner Complexes were formed pairing FX, FHY, FH2Z, and FH3T (X = Cl, Br, I; Y = S, Se, Te; Z = P, As, Sb; T = Si, Ge, Sn) with NH3 in order to form an A⋯N noncovalent bond, where A refers to the central atom. Geometries, energetics, atomic charges, and spectroscopic characteristics of these complexes were...
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