Plants, Vol. 8, Pages 265: Antioxidant, Antidiabetic, and Anticholinesterase Activities and Phytochemical Profile of Azorella glabra Wedd Plants doi: 10.3390/plants8080265 Authors: Immacolata Faraone Dilip K. Rai Daniela Russo Lucia Chiummiento Eloy Fernandez Alka Choudhary Luigi Milella Oxidative stress is involved in different diseases, such as diabetes and neurodegenerative diseases. The genus Azorella includes about 70 species of flowering plant species; most of...
Sat Aug 03, 2019 03:00
Molecules, Vol. 24, Pages 2832: MMI-0100 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice through Targeting MK2 Pathway Molecules doi: 10.3390/molecules24152832 Authors: Zhe Wang Xue Ya Liang Xin Chang Yao Yan Nie Chen Guo Jin Hong Jiang Min Chang Backgrounds: This study aimed to investigate the protective effects of MMI-0100, a cell-penetrating peptide inhibitor of MAPK-activated protein kinase II (MK2), on acute colitis induced by dextran sodium sulfate...
Sat Aug 03, 2019 03:00
IJMS, Vol. 20, Pages 3803: Arabidopsis Trichome Contains Two Plasma Membrane Domains with Different Lipid Compositions Which Attract Distinct EXO70 Subunits International Journal of Molecular Sciences doi: 10.3390/ijms20153803 Authors: Zdeňka Kubátová Přemysl Pejchar Martin Potocký Juraj Sekereš Viktor Žárský Ivan Kulich Plasma membrane (PM) lipid composition and domain organization are modulated by polarized exocytosis. Conversely, targeting of secretory vesicles at specific...
Sat Aug 03, 2019 03:00
IJMS, Vol. 20, Pages 3802: Dihydroxy-Substituted Coumarins as Fluorescent Probes for Nanomolar-Level Detection of the 4-Amino-TEMPO Spin Label International Journal of Molecular Sciences doi: 10.3390/ijms20153802 Authors: Krzysztof Żamojć Magdalena Zdrowowicz Aleksandra Hać Maciej Witwicki Paweł Błażej Rudnicki-Velasquez Dariusz Wyrzykowski Wiesław Wiczk Lech Chmurzyński This paper reports on dihydroxycoumarins as fluorescent probes suitable for the detection and...
Sat Aug 03, 2019 03:00
IJMS, Vol. 20, Pages 3798: Claudin-7 Modulates Cl− and Na+ Homeostasis and WNK4 Expression in Renal Collecting Duct Cells International Journal of Molecular Sciences doi: 10.3390/ijms20153798 Authors: Junming Fan Rodney Tatum John Hoggard Yan-Hua Chen Claudin-7 knockout (CLDN7−/−) mice display renal salt wasting and dehydration phenotypes. To address the role of CLDN7 in kidneys, we established collecting duct (CD) cell lines from CLDN7+/+ and CLDN7−/−...
Sat Aug 03, 2019 03:00
IJMS, Vol. 20, Pages 3801: Flexible and Expedited Regulatory Review Processes for Innovative Medicines and Regenerative Medical Products in the US, the EU, and Japan International Journal of Molecular Sciences doi: 10.3390/ijms20153801 Authors: Sumimasa Nagai Several expedited regulatory review projects for innovative drugs and regenerative medical products have been developed in the US, the EU, and Japan. Each regulatory agency has elaborated an original regulatory framework and adopted...
Sat Aug 03, 2019 03:00
IJMS, Vol. 20, Pages 3800: Therapeutic Effect of Ecdysterone Combine Paeonol Oral Cavity Direct Administered on Radiation-Induced Oral Mucositis in Rats International Journal of Molecular Sciences doi: 10.3390/ijms20153800 Authors: Li Yang Jian Pan Radiation-induced oral mucositis represents an influential factor in cancer patients’ accepted radiation therapy, especially in head and neck cancer. This research investigates the treatment effect of Ecdysterone (a steroid derived...
Sat Aug 03, 2019 03:00
IJERPH, Vol. 16, Pages 2783: Children Exposure-Related Behavior Patterns and Risk Perception Associated with Recreational Beach Use International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16152783 Authors: Alesia Ferguson Courtney Del Donno Emmanuel Obeng-Gyasi Kristina Mena Tanu Kaur Altomare Rosalía Guerrero Maribeth Gidley Larissa Montas Helena M. Solo-Gabriele Background: Oil spill chemicals (OSCs) result not only from the crude...
Sat Aug 03, 2019 03:00
Cells, Vol. 8, Pages 823: Combination Therapy of Mesenchymal Stromal Cells and Interleukin-4 Attenuates Rheumatoid Arthritis in a Collagen-Induced Murine Model Cells doi: 10.3390/cells8080823 Authors: Shaimaa M. Haikal Nourtan F. Abdeltawab Laila A. Rashed Tarek I. Abd El-Galil Heba A. Elmalt Magdy A. Amin Rheumatoid arthritis (RA) is a disease of the joints that causes decreased quality of life. Mesenchymal stromal cells (MSCs) have immunosuppressive properties, with...
Sat Aug 03, 2019 03:00
Cells, Vol. 8, Pages 825: The Molecular Basis for Remyelination Failure in Multiple Sclerosis Cells doi: 10.3390/cells8080825 Authors: Joel Gruchot Vivien Weyers Peter Göttle Moritz Förster Hans-Peter Hartung Patrick Küry David Kremer Myelin sheaths in the central nervous system (CNS) insulate axons and thereby allow saltatory nerve conduction, which is a prerequisite for complex brain function. Multiple sclerosis (MS), the most common inflammatory autoimmune disease...
Sat Aug 03, 2019 03:00
Cells, Vol. 8, Pages 826: WNT Signaling in Disease Cells doi: 10.3390/cells8080826 Authors: Ng Kaur Bunnag Suresh Sung Tan Gruber Tolwinski Developmental signaling pathways control a vast array of biological processes during embryogenesis and in adult life. The WNT pathway was discovered simultaneously in cancer and development. Recent advances have expanded the role of WNT to a wide range of pathologies in humans. Here, we discuss the WNT pathway and its...
Sat Aug 03, 2019 03:00
Cells, Vol. 8, Pages 824: Investigation of Cytokine Changes in Osteoarthritic Knee Joint Tissues in Response to Hyperacute Serum Treatment Cells doi: 10.3390/cells8080824 Authors: Dorottya Kardos Bence Marschall Melinda Simon István Hornyák Adél Hinsenkamp Olga Kuten Zsuzsanna Gyevnár Gábor Erdélyi Tamás Bárdos Tamás Mirkó Paukovits Krisztián Magos György Béres Kálmán Szenthe Ferenc Bánáti Susan Szathmary Stefan Nehrer Zsombor Lacza One...
Sat Aug 03, 2019 03:00
Biomolecules, Vol. 9, Pages 339: Acute vs. Chronic vs. Cyclic Hypoxia: Their Differential Dynamics, Molecular Mechanisms, and Effects on Tumor Progression Biomolecules doi: 10.3390/biom9080339 Authors: Saxena Jolly Hypoxia has been shown to increase the aggressiveness and severity of tumor progression. Along with chronic and acute hypoxic regions, solid tumors contain regions of cycling hypoxia (also called intermittent hypoxia or IH). Cyclic hypoxia is mimicked in vitro and in...
Sat Aug 03, 2019 03:00
Biomolecules, Vol. 9, Pages 340: Vaccine Adjuvants Derived from Marine Organisms Biomolecules doi: 10.3390/biom9080340 Authors: Nina Sanina Vaccine adjuvants help to enhance the immunogenicity of weak antigens. The adjuvant effect of certain substances was noted long ago (the 40s of the last century), and since then a large number of adjuvants belonging to different groups of chemicals have been studied. This review presents research data on the nonspecific action of substances originated...
Sat Aug 03, 2019 03:00
Biomolecules, Vol. 9, Pages 341: The TGF-β1/p53/PAI-1 Signaling Axis in Vascular Senescence: Role of Caveolin-1 Biomolecules doi: 10.3390/biom9080341 Authors: Rohan Samarakoon Stephen P. Higgins Craig E. Higgins Paul J. Higgins Stress-induced premature cellular senescence is a significant factor in the onset of age-dependent disease in the cardiovascular system. Plasminogen activator inhibitor-1 (PAI-1), a major TGF-β1/p53 target gene and negative regulator of the plasmin-based...
Sat Aug 03, 2019 03:00
IJMS, Vol. 20, Pages 3797: Inhibition of Ihh Reverses Temporomandibular Joint Osteoarthritis via a PTH1R Signaling Dependent Mechanism International Journal of Molecular Sciences doi: 10.3390/ijms20153797 Authors: Hongxu Yang Mian Zhang Qian Liu Hongyun Zhang Jing Zhang Lei Lu Mianjiao Xie Di Chen Meiqing Wang The temporomandibular joint (TMJ), which is biomechanically related to dental occlusion, is often insulted by osteoarthritis (OA). This study was conducted...
Sat Aug 03, 2019 03:00
IJMS, Vol. 20, Pages 3799: Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrates International Journal of Molecular Sciences doi: 10.3390/ijms20153799 Authors: Josè Manuel Pioner Lorenzo Santini Chiara Palandri Daniele Martella Flavia Lupi Marianna Langione Silvia Querceto Bruno Grandinetti Valentina Balducci Patrizia Benzoni Sara Landi Andrea Barbuti Federico Ferrarese Lupi Luca Boarino...
Sat Aug 03, 2019 03:00
Water, Vol. 11, Pages 1612: A New National Water Quality Model to Evaluate the Effectiveness of Catchment Management Measures in England Water doi: 10.3390/w11081612 Authors: Barry Hankin Johan Strömqvist Chris Burgess Charlotta Pers Sally Bielby Beatriz Revilla-Romero Linda Pope This investigation reports on a new national model to evaluate the effectiveness of catchment sensitive farming in England, and how pollution mitigation measures have improved water quality...
Sat Aug 03, 2019 03:00
IJERPH, Vol. 16, Pages 2778: Effects of Parenting Styles on Self-Regulated Learning and Academic Stress in Spanish Adolescents International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16152778 Authors: María C. Fuentes Rafael García-Ros Francisco Pérez-González Dolores Sancerni Research has repeatedly highlighted the important influence of parental socialization styles on children’s psychosocial adjustment. However, previous studies about...
Sat Aug 03, 2019 03:00
IJERPH, Vol. 16, Pages 2781: Costs of Hospitalization for Dementia in Urban China: Estimates from Two Urban Health Insurance Scheme Claims Data in Guangzhou City International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16152781 Authors: Hui Zhang Donglan Zhang Yujie Yin Chao Zhang Yixiang Huang Background: Dementia is one of the public health priorities in China. This study aimed to examine the hospitalization costs of patients with dementia and...
Sat Aug 03, 2019 03:00
IJERPH, Vol. 16, Pages 2780: Construction and Validation of an Analytical Grid about Video Representations of Suicide (“MoVIES”) International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16152780 Authors: Christophe Gauld Marielle Wathelet François Medjkane Nathalie Pauwels Thierry Bougerol Charles-Edouard Notredame Background. Exposure to fictional suicide scenes raises concerns about the risk of suicide contagion. However, researchers and clinicians...
Sat Aug 03, 2019 03:00
IJERPH, Vol. 16, Pages 2779: Community Advantage and Individual Self-Efficacy Promote Disaster Preparedness: A Multilevel Model among Persons with Disabilities International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16152779 Authors: Rachel M. Adams David P. Eisenman Deborah Glik Disaster preparedness initiatives are increasingly focused on building community resilience. Preparedness research has correspondingly shifted its attention to community-level...
Sat Aug 03, 2019 03:00
IJERPH, Vol. 16, Pages 2782: Popularity and Friendships and Their Relationship to Physical Activity Before and After Transition to a Higher School Grade International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16152782 Authors: Kenda C. Swanson Alberto Nettel-Aguirre Gavin R. McCormack Background This study investigated the relationships between children’s friendship ties and their physical activity (PA) both before and after their transition...
Sat Aug 03, 2019 03:00
Antibiotics, Vol. 8, Pages 110: Mitochondrial Toxicity of Azithromycin Results in Aerobic Glycolysis and DNA Damage of Human Mammary Epithelia and Fibroblasts Antibiotics doi: 10.3390/antibiotics8030110 Authors: Xianpeng Jiang Catherine Baucom Robert L. Elliott Mitochondria evolved from free-living bacteria via endocytosis within eukaryotic host cells millions of year ago. We hypothesized that antibiotics cause mammalian mitochondrial damage while causing bacterial lethality. Mitochondrial...
Sat Aug 03, 2019 03:00
Molecules, Vol. 24, Pages 2831: Antibacterial Activity and Mode of Action of Dihydromyricetin from Ampelopsis grossedentata Leaves against Food-Borne Bacteria Molecules doi: 10.3390/molecules24152831 Authors: Xiao-Nian Xiao Fan Wang Yi-Ting Yuan Jing Liu Yue-Zhen Liu Xing Yi Dihydromyricetin (DMY) has recently attracted increased interest due to its considerable health-promoting activities but there are few reports on its antibacterial activity and mechanism. In this paper,...
Sat Aug 03, 2019 03:00
Molecules, Vol. 24, Pages 2830: An Explanation about the Use of (S)-Citronellal as a Chiral Derivatizing Agent (CDA) in 1H and 13C NMR for Sec-Butylamine, Methylbenzylamine, and Amphetamine: A Theoretical-Experimental Study Molecules doi: 10.3390/molecules24152830 Authors: Viviani Nardini Vinicius Palaretti Luis Gustavo Dias Gil Valdo José da Silva A chiral derivatizing agent (CDA) with the aldehyde function has been widely used in discriminating chiral amines because of the...
Sat Aug 03, 2019 03:00
Microorganisms, Vol. 7, Pages 237: Development of a Biocontrol Method Applying Bacteriophage-Containing Aerosol against Mycobacterium tuberculosis Using the Bacteriophage BTCU-1 and M. smegmatis as Models Microorganisms doi: 10.3390/microorganisms7080237 Authors: Chun-Chieh Tseng Dan Chi Chang Kai-Chih Chang The application of bacteriophages for biocontrol has attracted increasing attention. Here, we applied ϕBTCU-1 as a model phage to develop a method for controlling Mycobacterium...
Sat Aug 03, 2019 03:00
Microorganisms, Vol. 7, Pages 238: Symbiosis in Sustainable Agriculture: Can Olive Fruit Fly Bacterial Microbiome Be Useful in Pest Management? Microorganisms doi: 10.3390/microorganisms7080238 Authors: Tânia Nobre The applied importance of symbiosis has been gaining recognition. The relevance of symbiosis has been increasing in agriculture, in developing sustainable practices, including pest management. Insect symbiotic microorganisms’ taxonomical and functional diversity...
Sat Aug 03, 2019 03:00
IJMS, Vol. 20, Pages 3796: GmFAD3A, A ω-3 Fatty Acid Desaturase Gene, Enhances Cold Tolerance and Seed Germination Rate under Low Temperature in Rice International Journal of Molecular Sciences doi: 10.3390/ijms20153796 Authors: Xin Wang Chao Yu Yi Liu Lu Yang Yang Li Wen Yao Yicong Cai Xin Yan Shaobo Li Yaohui Cai Shaoqing Li Xiaojue Peng Low temperature is an environmental stress factor that is always been applied in research on improving crop growth,...
Sat Aug 03, 2019 03:00
IJMS, Vol. 20, Pages 3795: Peroxisomes and Innate Immunity: Antiviral Response and Beyond International Journal of Molecular Sciences doi: 10.3390/ijms20153795 Authors: Ana Rita Ferreira Mariana Marques Daniela Ribeiro Peroxisomes are ubiquitous organelles with well-defined functions in lipid and reactive oxygen species metabolism, having a significant impact on a large number of important diseases. Growing evidence points to them, in concert with mitochondria, as important players...
Sat Aug 03, 2019 03:00
Religions, Vol. 10, Pages 462: The “Original Position” as Public Performance: Liberalism, Pluralism, and Asceticism Religions doi: 10.3390/rel10080462 Authors: Joseph Rivera John Rawls’ well-known device of representation (his terminology) that he names the “original position” is put into play by the veil of ignorance. This imaginative device, found in both his early and late works, is often dismissed because it is misunderstood as an exercise in moral geometry....
Sat Aug 03, 2019 03:00
Religions, Vol. 10, Pages 463: Mediatized Catholicism—Minority Voices and Religious Authority in the Digital Sphere Religions doi: 10.3390/rel10080463 Authors: Alberta Giorgi Over the last decade, many scholars have explored the thesis of the mediatization of religion proposed by Hjarvard and how mediatization has impacted religious authority. While some scholars have underlined the increasing opportunities for marginalized religious actors to make their voices heard, others have explored...
Sat Aug 03, 2019 03:00
JCM, Vol. 8, Pages 1162: Review of Systemic Antibiotic Treatments in Children with Rhinosinusitis Journal of Clinical Medicine doi: 10.3390/jcm8081162 Authors: Sara Torretta Lorenzo Drago Paola Marchisio Lorenzo Gaini Claudio Guastella Antonio Moffa Vittorio Rinaldi Manuel Casale Lorenzo Pignataro Antibiotic treatment in paediatric rhinosinusitis is still a matter of debate, as the current guidelines have been drafted mainly based on clinical studies published...
Sat Aug 03, 2019 03:00
JCM, Vol. 8, Pages 1164: Efficacy and Safety of Belatacept Treatment in Renal Allograft Recipients at High Cardiovascular Risk—A Single Center Experience Journal of Clinical Medicine doi: 10.3390/jcm8081164 Authors: Hannes Neuwirt Irmgard Leitner-Lechner Julia Kerschbaum Michael Ertl Florian Pöggsteiner Nicolas Pölt Julius Mätzler Hannelore Sprenger-Mähr Michael Rudnicki Peter Schratzberger Iris E. Eder Gert Mayer Belatacept is an attractive option for...
Sat Aug 03, 2019 03:00
Foods, Vol. 8, Pages 314: Influence of Variety and Storage Time of Fresh Garlic on the Physicochemical and Antioxidant Properties of Black Garlic Foods doi: 10.3390/foods8080314 Authors: M. Ángeles Toledano Medina Jesús Pérez-Aparicio Alicia Moreno-Ortega Rafael Moreno-Rojas Black garlic is made from the fresh kind, submitting it to a controlled temperature (~65 °C) and humidity (>85 °C) for a prolonged period of time. The aim of this study was to assess...
Sat Aug 03, 2019 03:00
Foods, Vol. 8, Pages 315: Effect of Season and Factory on Cheese-Making Efficiency in Parmigiano Reggiano Manufacture Foods doi: 10.3390/foods8080315 Authors: Piero Franceschi Massimo Malacarne Paolo Formaggioni Claudio Cipolat-Gotet Giorgia Stocco Andrea Summer The assessment of the efficiency of the cheese-making process (ECMP) is crucial for the profitability of cheese-factories. A simple way to estimate the ECMP is the measure of the estimated cheese-making losses...
Sat Aug 03, 2019 03:00
Nanomaterials, Vol. 9, Pages 1117: Detwinning Mechanism for Nanotwinned Cubic Boron Nitride with Unprecedented Strength: A First-Principles Study Nanomaterials doi: 10.3390/nano9081117 Authors: Bo Yang Xianghe Peng Sha Sun Cheng Huang Deqiang Yin Xiang Chen Tao Fu Synthesized nanotwinned cubic boron nitride (nt-cBN) and nanotwinned diamond (nt-diamond) exhibit extremely high hardness and excellent stability, in which nanotwinned structure plays a crucial role. Here...
Sat Aug 03, 2019 03:00
Nanomaterials, Vol. 9, Pages 1116: Ferroelectric Polarization-Enhanced Photocatalysis in BaTiO3-TiO2 Core-Shell Heterostructures Nanomaterials doi: 10.3390/nano9081116 Authors: Xiaoyan Liu Siyi Lv Baoyan Fan An Xing Bi Jia Suppressing charge recombination and improving carrier transport are key challenges for the enhancement of photocatalytic activity of heterostructured photocatalysts. Here, we report a ferroelectric polarization-enhanced photocatalysis on the basis of BaTiO3-TiO2...
Sat Aug 03, 2019 03:00
Pharmacy, Vol. 7, Pages 105: Deprescribing of Medicines in Care Homes—A Five-Year Evaluation of Primary Care Pharmacist Practices Pharmacy doi: 10.3390/pharmacy7030105 Authors: Ana Alves Shaun Green Delyth H James (1) Background: This project evaluates the outcomes of a novel pharmacy-led model of deprescribing unnecessary medications for care home patients. A feasibility study was conducted in 2015 to explore exposure to inappropriate polypharmacy in patients residing in care...
Sat Aug 03, 2019 03:00
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