Πέμπτη 15 Αυγούστου 2019


Towards endemicity: large-scale expansion of the NDM-1-producing Klebsiella pneumoniae ST11 lineage in Poland, 2015-16.
Towards endemicity: large-scale expansion of the NDM-1-producing Klebsiella pneumoniae ST11 lineage in Poland, 2015-16. J Antimicrob Chemother. 2019 Aug 13;: Authors: Baraniak A, Machulska M, Å»abicka D, Literacka E, Izdebski R, Urbanowicz P, Bojarska K, Herda M, KoziÅska A, Hryniewicz W, Gniadkowski M, NDM-PL Study Group Abstract OBJECTIVES: In 2015 and 2016 Poland recorded rapid proliferation of New Delhi MBL (NDM)-producing Enterobacterales, with...
Oncology
1d
Resistance to TRK inhibition mediated by convergent MAPK pathway activation.
Resistance to TRK inhibition mediated by convergent MAPK pathway activation. Nat Med. 2019 Aug 12;: Authors: Cocco E, Schram AM, Kulick A, Misale S, Won HH, Yaeger R, Razavi P, Ptashkin R, Hechtman JF, Toska E, Cownie J, Somwar R, Shifman S, Mattar M, Selçuklu SD, Samoila A, Guzman S, Tuch BB, Ebata K, de Stanchina E, Nagy RJ, Lanman RB, Houck-Loomis B, Patel JA, Berger MF, Ladanyi M, Hyman DM, Drilon A, Scaltriti M Abstract TRK fusions are found in...
Oncology
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In order for the light to shine so brightly, the darkness must be present-why do cancers fluoresce with 5-aminolaevulinic acid?
In order for the light to shine so brightly, the darkness must be present-why do cancers fluoresce with 5-aminolaevulinic acid? Br J Cancer. 2019 Aug 13;: Authors: McNicholas K, MacGregor MN, Gleadle JM Abstract Photodynamic diagnosis and therapy have emerged as a promising tool in oncology. Using the visible fluorescence from photosensitisers excited by light, clinicians can both identify and treat tumour cells in situ. Protoporphyrin IX, produced in...
Oncology
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HER2, chromosome 17 polysomy and DNA ploidy status in breast cancer; a translational study.
HER2, chromosome 17 polysomy and DNA ploidy status in breast cancer; a translational study. Sci Rep. 2019 Aug 12;9(1):11679 Authors: Halilovic A, Verweij DI, Simons A, Stevens-Kroef MJPL, Vermeulen S, Elsink J, Tops BBJ, Otte-Höller I, van der Laak JAWM, van de Water C, Boelens OBA, Schlooz-Vries MS, Dijkstra JR, Nagtegaal ID, Tol J, van Cleef PHJ, Span PN, Bult P Abstract Breast cancer treatment depends on human epidermal growth factor receptor-2 (HER2)...
Oncology
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Biosimilars in oncology: A decade of experience with granulocyte colony-stimulating factor and its implications for monoclonal antibodies.
Biosimilars in oncology: A decade of experience with granulocyte colony-stimulating factor and its implications for monoclonal antibodies. Crit Rev Oncol Hematol. 2019 Jul 23;: Authors: Krendyukov A, Schiestl M Abstract Biosimilars offer the potential for improved sustainability of cancer care. In oncology, granulocyte colony-stimulating factor and erythropoiesis-stimulating agent biosimilars have been available for almost a decade, with biosimilars...
Oncology
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Breast Cancer Epidemiology among Lebanese Women: An 11-Year Analysis.
Related ArticlesBreast Cancer Epidemiology among Lebanese Women: An 11-Year Analysis. Medicina (Kaunas). 2019 Aug 10;55(8): Authors: Fares MY, Salhab HA, Khachfe HH, Khachfe HM Abstract Background and Objectives: Breast cancer is the most prevalent cancer in women worldwide. Lebanon is a developing country in the Middle East with a prominent breast cancer incidence. The aim of our study was to explore the incidence rates of breast cancer in Lebanon from...
Oncology
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Downregulation of microRNA-1246 inhibits tumor growth and promotes apoptosis of cervical cancer cells by targeting thrombospondin-2.
Related ArticlesDownregulation of microRNA-1246 inhibits tumor growth and promotes apoptosis of cervical cancer cells by targeting thrombospondin-2. Oncol Lett. 2019 Sep;18(3):2491-2499 Authors: Du P, Lai YH, Yao DS, Chen JY, Ding N Abstract Cervical cancer pathogenesis is regulated by numerous factors, including microRNAs. MicroRNA 1246 (miR-1246) has been shown to serve a role in cervical cancer tumorigenesis. However, the mechanisms through which...
Oncology
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Antibiotic use is a negative predictor of the efficacy and toxicity of epidermal growth factor receptor-targeted therapy in advanced non-small cell lung cancer.
Related ArticlesAntibiotic use is a negative predictor of the efficacy and toxicity of epidermal growth factor receptor-targeted therapy in advanced non-small cell lung cancer. Oncol Lett. 2019 Sep;18(3):2677-2683 Authors: Liu K, Zhang W, Tan Q, Jiang G, Jia J Abstract Non-small cell lung cancer (NSCLC) is closely associated with inflammation and chronic infection. Antibiotics are frequently prescribed for NSCLC patients in combination with epidermal...
Oncology
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Meta-analysis of gene expression alterations and clinical significance of the HECT domain-containing ubiquitin ligase HUWE1 in cancer.
Related ArticlesMeta-analysis of gene expression alterations and clinical significance of the HECT domain-containing ubiquitin ligase HUWE1 in cancer. Oncol Lett. 2019 Sep;18(3):2292-2303 Authors: Su C, Wang T, Zhao J, Cheng J, Hou J Abstract E3 ubiquitin-protein ligase (HUWE1) has previously been identified as a HECT domain-containing ubiquitin ligase (E3) that is involved in several signaling pathways, transcriptional regulation, neural differentiation,...
Oncology
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Allocation of Treatment Responsibility and Adherence to Hydroxyurea Among Adolescents With Sickle Cell Disease.
Related ArticlesAllocation of Treatment Responsibility and Adherence to Hydroxyurea Among Adolescents With Sickle Cell Disease. J Pediatr Psychol. 2019 Aug 12;: Authors: Creary SE, Modi AC, Stanek JR, Chisolm DJ, O'Brien SH, Nwankwo C, Crosby LE Abstract OBJECTIVE: Adolescents with sickle cell disease (SCD) are at increased risk for complications. Hydroxyurea is a medication that can ameliorate risk but to benefit, adolescents must adhere to treatment....
Oncology
1d
Clinicopathologic Diagnostic Approach to Aggressive Variant Prostate Cancer.
Related ArticlesClinicopathologic Diagnostic Approach to Aggressive Variant Prostate Cancer. Arch Pathol Lab Med. 2019 Aug 12;: Authors: Manucha V, Henegan J Abstract CONTEXT.—: Aggressive variant prostate cancer (AVPCa) develops in a subset of patients with metastatic castration-resistant prostate cancer. The clinical and histologic overlap of AVPCa with other neuroendocrine carcinomas of the prostate has resulted in a lack of consensus on its terminology...
Oncology
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Platelets and Immune Responses During Thromboinflammation.
Related ArticlesPlatelets and Immune Responses During Thromboinflammation. Front Immunol. 2019;10:1731 Authors: Mezger M, Nording H, Sauter R, Graf T, Heim C, von Bubnoff N, Ensminger SM, Langer HF Abstract Besides mediating hemostatic functions, platelets are increasingly recognized as important players of inflammation. Data from experiments in mice and men revealed various intersection points between thrombosis, hemostasis, and inflammation, which...
Oncology
1d
Targeted gene therapy in human-induced pluripotent stem cells from a patient with primary hyperoxaluria type 1 using CRISPR/Cas9 technology.
Related ArticlesTargeted gene therapy in human-induced pluripotent stem cells from a patient with primary hyperoxaluria type 1 using CRISPR/Cas9 technology. Biochem Biophys Res Commun. 2019 Aug 08;: Authors: Estève J, Blouin JM, Lalanne M, Azzi-Martin L, Dubus P, Bidet A, Harambat J, Llanas B, Moranvillier I, Bedel A, Moreau-Gaudry F, Richard E Abstract Primary hyperoxaluria type 1 (PH1) is an inherited metabolic disorder caused by a deficiency of the...
Oncology
1d
Dacomitinib in non-small-cell lung cancer: a comprehensive review for clinical application.
Related ArticlesDacomitinib in non-small-cell lung cancer: a comprehensive review for clinical application. Future Oncol. 2019 Aug 12;: Authors: Sun H, Wu Y Abstract Dacomitinib is a second-generation EGFR tyrosine kinase inhibitor (TKI) that irreversibly binds to and inhibits EGFR/Her1, Her2 and Her4 subtypes with an efficacy comparable to other TKIs. In the ARCHER 1050 trial, progression-free survival was improved by dacomitinib compared with gefitinib,...
Oncology
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The Microbiome and Genitourinary Cancer: A Collaborative Review.
Related ArticlesThe Microbiome and Genitourinary Cancer: A Collaborative Review. Eur Urol. 2019 04;75(4):637-646 Authors: Markowski MC, Boorjian SA, Burton JP, Hahn NM, Ingersoll MA, Maleki Vareki S, Pal SK, Sfanos KS Abstract CONTEXT: The recent discovery of the existence of a human genitourinary microbiome has led to the investigation of its role in mediating the pathogenesis of genitourinary malignancies, including bladder, kidney, and prostate cancers....
Oncology
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Hypothyroidism in patients with hepatocellular carcinoma receiving cabozantinib: an unassessed issue.
Related ArticlesHypothyroidism in patients with hepatocellular carcinoma receiving cabozantinib: an unassessed issue. Future Oncol. 2019 Feb;15(6):563-565 Authors: Di Nunno V, Frega G, Gatto L, Brandi G, Massari F PMID: 30648889 [PubMed - indexed for MEDLINE]
Oncology
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Role of the receptor tyrosine kinase Axl in hepatocellular carcinoma and its clinical relevance.
Related ArticlesRole of the receptor tyrosine kinase Axl in hepatocellular carcinoma and its clinical relevance. Future Oncol. 2019 Feb;15(6):653-662 Authors: Niu ZS, Niu XJ, Wang WH Abstract The receptor tyrosine kinase Axl and its ligand Gas6 regulate fundamental biological processes, including cell proliferation, survival and motility, through multiple downstream signaling pathways. Evidence to date suggests that aberrant Axl expression frequently...
Oncology
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Early Integration of Palliative and Oncological Care: Con.
Related ArticlesEarly Integration of Palliative and Oncological Care: Con. Oncol Res Treat. 2019;42(1-2):19-24 Authors: Schuler US Abstract For almost a decade, 'early integration' has become a buzzword in the palliative care community. Can this still be an issue of controversy? The goals of care in palliative medicine are beyond any criticism and in fact should be, at least in theory, goals of good oncological care. However, the reality presents a...
Oncology
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Pilot study of the potential of 3D ultrasound to measure tonsillar volume and hypertrophy.
Pilot study of the potential of 3D ultrasound to measure tonsillar volume and hypertrophy. Int J Pediatr Otorhinolaryngol. 2019 Jul 31;126:109612 Authors: Chung D, Bandarkar A, Rana MS, Tabrizi PR, Preciado D, Jago J, Linguraru MG, Reilly BK Abstract OBJECTIVE: Obstructive sleep apnea (OSA), results in approximately 4-5 million outpatient visits per year in the United States. In pediatric patients, OSA is primarily caused by adenotonsillar hypertrophy,...
International journal of pediatric otorhinolaryngology,http://goo.gl/4YdRhz
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The bacteriome of otitis media with effusion: Does it originate from the adenoid?
The bacteriome of otitis media with effusion: Does it originate from the adenoid? Int J Pediatr Otorhinolaryngol. 2019 Aug 07;126:109624 Authors: Ari O, Karabudak S, Kalcioglu MT, Gunduz AY, Durmaz R Abstract OBJECTIVE: The aim of this study was to evaluate the composition and the diversity of bacteriome in middle ear effusion (MEE) and adenoid specimens of pediatric patients having otitis media with effusion (OME). MATERIALS AND METHODS: Sample...
International journal of pediatric otorhinolaryngology,http://goo.gl/4YdRhz
1d
In vitro inhibitory activity of N-acetylcysteine on tympanostomy tube biofilms from methicillin-resistant Staphylococcus aureus and quinolone-resistant Pseudomonas aeruginosa.
Related ArticlesIn vitro inhibitory activity of N-acetylcysteine on tympanostomy tube biofilms from methicillin-resistant Staphylococcus aureus and quinolone-resistant Pseudomonas aeruginosa. Int J Pediatr Otorhinolaryngol. 2019 Aug 06;126:109622 Authors: Jun Y, Youn CK, Jo ER, Cho SI Abstract OBJECTIVES: Biofilm formation in tympanostomy tubes causes persistent and refractory otorrhea. In the present study, we investigated the in vitro antibiofilm activity...
International journal of pediatric otorhinolaryngology,http://goo.gl/4YdRhz
1d
Button battery versus stacked coin ingestion: A conundrum for radiographic diagnosis.
Related ArticlesButton battery versus stacked coin ingestion: A conundrum for radiographic diagnosis. Int J Pediatr Otorhinolaryngol. 2019 Aug 06;126:109627 Authors: Whelan R, Shaffer A, Dohar JE Abstract OBJECTIVES: Given the potential for devastating complications associated with esophageal impaction of a button battery, there is a need to distinguish between a button battery and look-alike stacked coins at the time of presentation. Given there have...
International journal of pediatric otorhinolaryngology,http://goo.gl/4YdRhz
1d
Commentary on "Correlation between students' and trainers' evaluations while learning delegated surgical procedures: a prospective cohort study".
Commentary on "Correlation between students' and trainers' evaluations while learning delegated surgical procedures: a prospective cohort study". Int J Surg. 2019 Aug 10;: Authors: Nazim SM, Talati JJ PMID: 31408747 [PubMed - as supplied by publisher]
International Journal of Surgery
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A novel hybrid fixation versus dual plating for both-bone forearm fractures in older children: a prospective comparative study.
A novel hybrid fixation versus dual plating for both-bone forearm fractures in older children: a prospective comparative study. Int J Surg. 2019 Aug 10;: Authors: Zhu S, Yang D, Gong C, Chen C, Chen L Abstract OBJECTIVE: The aim of the present study was to compare the clinical outcomes of hybrid fixation using elastic stable intramedullary nailing (ESIN) for the ulna and plate screw fixation for the radius (Hybrid group) with dual plating fixation for...
International Journal of Surgery
1d
Systematic review and meta-analysis Comparing weight loss outcomes by laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy; a systematic review and meta-analysis.
Systematic review and meta-analysis Comparing weight loss outcomes by laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy; a systematic review and meta-analysis. Int J Surg. 2019 Aug 10;: Authors: Guraya SY, Strate T Abstract OBJECTIVE: Laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic sleeve gastrectomy (LSG) are commonly performed weight loss procedures worldwide. Unfortunately, few studies have compared percentage total weight...
International Journal of Surgery
1d
Commentary on "Short-term efficacy of transvaginal specimen extraction for right colon cancer based on propensity score matching: a retrospective cohort study".
Commentary on "Short-term efficacy of transvaginal specimen extraction for right colon cancer based on propensity score matching: a retrospective cohort study". Int J Surg. 2019 Aug 10;: Authors: Coskun AK PMID: 31408744 [PubMed - as supplied by publisher]
International Journal of Surgery
1d
Thermal ablation versus parathyroidectomy for secondary hyperparathyroidism: A Meta-analysis.
Related ArticlesThermal ablation versus parathyroidectomy for secondary hyperparathyroidism: A Meta-analysis. Int J Surg. 2019 Aug 09;: Authors: Gong L, Tang W, Lu J, Xu W Abstract OBJECTIVE: Thermal ablation and parathyroidectomy (PTX) have been recommended for patients with secondary hyperparathyroidism (SHPT). However, it is uncertain which is the better method. The aim of the present meta-analysis was to evaluate the efficacy and surgical complications...
International Journal of Surgery
1d
Bedside ultrasonography for acute appendicitis: an updated diagnostic meta-analysis.
Related ArticlesBedside ultrasonography for acute appendicitis: an updated diagnostic meta-analysis. Int J Surg. 2019 Aug 09;: Authors: Shen G, Wang J, Fei F, Mao M, Mei Z Abstract BACKGROUND: Bedside ultrasonography is a promising tool for identification of acute appendicitis. We assessed the accuracy and clinical value of bedside ultrasonography for diagnosis of acute appendicitis in the emergency department. METHODS: Pubmed, Embase and Cochrane...
International Journal of Surgery
1d
Effect of micro-computed tomography reconstruction protocols on bone fractal dimension analysis.
Effect of micro-computed tomography reconstruction protocols on bone fractal dimension analysis. Dentomaxillofac Radiol. 2019 Aug 13;:20190235 Authors: Gaêta-Araujo H, Oliveira-Santos N, Brasil DM, do Nascimento EHL, Madlum DV, Haiter-Neto F, Oliveira-Santos C Abstract OBJECTIVES: To evaluate the influence of the level of three micro-CT reconstruction tools: beam-hardening correction (BHC), smoothing filter (SF), and ring artefact correction (RAC) on...
dentomaxillofac rad
1d
Discrimintion and Mapping of the Primary and Processed Transcripts in Maize Mitochondrion Using a Circular RT-PCR-based Strategy.
Related ArticlesDiscrimintion and Mapping of the Primary and Processed Transcripts in Maize Mitochondrion Using a Circular RT-PCR-based Strategy. J Vis Exp. 2019 Jul 29;(149): Authors: Zhang Y, Liao X, Luo P, Peng K, Ye W, Lian T, Ma Q, Nian H Abstract In plant mitochondria, some steady-state transcripts have 5' triphosphate derived from transcription initiation (primary transcripts), while the others contain 5' monophosphate generated post-transcriptionally...
Journal of visualized experiments : JoVE,http://www.jove.com/
1d
Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography.
Related ArticlesDetecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography. J Vis Exp. 2019 Jul 26;(149): Authors: Rassi E, Fuscà M, Weisz N, Demarchi G Abstract Pre-stimulus oscillatory brain activity influences upcoming perception. The characteristics of this pre-stimulus activity can predict whether a near-threshold stimulus will be perceived or not perceived, but can they also predict which one of two competing stimuli...
Journal of visualized experiments : JoVE,http://www.jove.com/
1d
Use of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes.
Related ArticlesUse of an Influenza Antigen Microarray to Measure the Breadth of Serum Antibodies Across Virus Subtypes. J Vis Exp. 2019 Jul 26;(149): Authors: Khan S, Jain A, Taghavian O, Nakajima R, Jasinskas A, Supnet M, Felgner J, Davies J, de Assis RR, Jan S, Obiero J, Strahsburger E, Pone EJ, Liang L, Davies DH, Felgner PL Abstract The influenza virus remains a significant cause of mortality worldwide due to the limited effectiveness of currently...
Journal of visualized experiments : JoVE,http://www.jove.com/
1d
Detection of Retrotransposition Activity of Hot LINE-1s by Long-Distance Inverse PCR.
Related ArticlesDetection of Retrotransposition Activity of Hot LINE-1s by Long-Distance Inverse PCR. J Vis Exp. 2019 Jul 27;(149): Authors: Pradhan B, Kauppi L Abstract Long interspersed nuclear elements 1 (LINE-1s) are the only family of mobile genetic elements in the human genome that can move autonomously. They do so by a process called retrotransposition wherein they transcribe to form an mRNA intermediate which is then consequently inserted into...
Journal of visualized experiments : JoVE,http://www.jove.com/
1d
Application of Biolayer Interferometry (BLI) for Studying Protein-Protein Interactions in Transcription.
Related ArticlesApplication of Biolayer Interferometry (BLI) for Studying Protein-Protein Interactions in Transcription. J Vis Exp. 2019 Jul 26;(149): Authors: Desai M, Di R, Fan H Abstract A transcription factor (TF) is a protein that regulates gene expression by interacting with the RNA polymerase, another TF, and/or template DNA. GrgA is a novel transcription activator found specifically in the obligate intracellular bacterial pathogen Chlamydia....
Journal of visualized experiments : JoVE,http://www.jove.com/
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4D Printed Bifurcated Stents with Kirigami-Inspired Structures.
Related Articles4D Printed Bifurcated Stents with Kirigami-Inspired Structures. J Vis Exp. 2019 Jul 25;(149): Authors: Kim D, Kim T, Lee YG Abstract Branched vessels, typically in the form of the letter "Y," can be narrowed or blocked, resulting in serious health problems. Bifurcated stents, which are hollow in the interior and exteriorly shaped to the branched vessels, surgically inserted inside the branched vessels, act as a supporting structure so...
Journal of visualized experiments : JoVE,http://www.jove.com/
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Ultrasonic-augmented Primary Adult Fibroblast Isolation.
Related ArticlesUltrasonic-augmented Primary Adult Fibroblast Isolation. J Vis Exp. 2019 Jul 29;(149): Authors: Künzel SR, Schaeffer C, Sekeres K, Mehnert CS, Schacht Wall SM, Newe M, Kämmerer S, El-Armouche A Abstract Primary adult fibroblasts have become an important tool to study fibrosis, fibroblast interactions and inflammation in all body tissues. Since primary fibroblasts cannot divide indefinitely due to myofibroblast differentiation or senescence...
Journal of visualized experiments : JoVE,http://www.jove.com/
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Optimization, Design and Avoiding Pitfalls in Manual Multiplex Fluorescent Immunohistochemistry.
Related ArticlesOptimization, Design and Avoiding Pitfalls in Manual Multiplex Fluorescent Immunohistochemistry. J Vis Exp. 2019 Jul 26;(149): Authors: Lazarus J, Akiska Y, Perusina Lanfranca M, Delrosario L, Sun L, Long D, Shi J, Crawford H, Di Magliano MP, Zou W, Frankel T Abstract Microenvironment evaluation of intact tissue for analysis of cell infiltration and spatial organization are essential in understanding the complexity of disease processes....
Journal of visualized experiments : JoVE,http://www.jove.com/
1d
Induced Differentiation of M Cell-like Cells in Human Stem Cell-derived Ileal Enteroid Monolayers.
Related ArticlesInduced Differentiation of M Cell-like Cells in Human Stem Cell-derived Ileal Enteroid Monolayers. J Vis Exp. 2019 Jul 26;(149): Authors: Fasciano AC, Blutt SE, Estes MK, Mecsas J Abstract M (microfold) cells of the intestine function to transport antigen from the apical lumen to the underlying Peyer's patches and lamina propria where immune cells reside and therefore contribute to mucosal immunity in the intestine. A complete understanding...
Journal of visualized experiments : JoVE,http://www.jove.com/
1d
Identification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry.
Related ArticlesIdentification of Inositol Phosphate or Phosphoinositide Interacting Proteins by Affinity Chromatography Coupled to Western Blot or Mass Spectrometry. J Vis Exp. 2019 Jul 26;(149): Authors: Cestari I Abstract Inositol phosphates and phosphoinositides regulate several cellular processes in eukaryotes, including gene expression, vesicle trafficking, signal transduction, metabolism, and development. These metabolites perform this regulatory...
Journal of visualized experiments : JoVE,http://www.jove.com/
1d

Fluorescence Angiography for Evaluation of Aneurysm Perfusion and Parent Artery Patency in Rat and Rabbit Aneurysm Models.
Related ArticlesFluorescence Angiography for Evaluation of Aneurysm Perfusion and Parent Artery Patency in Rat and Rabbit Aneurysm Models. J Vis Exp. 2019 Jul 24;(149): Authors: Strange F, Sivanrupan S, Gruter BE, Rey J, Taeschler D, Fandino J, Marbacher S Abstract Brain aneurysm treatment focuses on achieving complete occlusion, as well as preserving blood flow in the parent artery. Fluorescein sodium and indocyanine green are used to enable the observation...
Journal of visualized experiments : JoVE,http://www.jove.com/
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Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease.
Related ArticlesDynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease. J Vis Exp. 2019 Jul 24;(149): Authors: Ryu J, Vero J, Dobkin RD, Torres EB Abstract As Parkinson's disease (PD) is a heterogeneous disorder, personalized medicine is truly required to optimize care. In their current form, standard scores from paper and pencil symptom- measures traditionally used to track disease progression are too coarse (discrete) to...
Journal of visualized experiments : JoVE,http://www.jove.com/
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Human Blastocyst Biopsy and Vitrification.
Related ArticlesHuman Blastocyst Biopsy and Vitrification. J Vis Exp. 2019 Jul 26;(149): Authors: Maggiulli R, Giancani A, Cimadomo D, Ubaldi FM, Rienzi L Abstract Blastocyst biopsy is performed to obtain a reliable genetic diagnosis during IVF cycles with preimplantation genetic testing. Then, the ideal workflow entails a safe and efficient vitrification protocol, due to the turnaround time of the diagnostic techniques and to transfer the selected embryo(s)...
Journal of visualized experiments : JoVE,http://www.jove.com/
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Simple Homemade Tools to Handle Fruit Flies-Drosophila melanogaster.
Related ArticlesSimple Homemade Tools to Handle Fruit Flies-Drosophila melanogaster. J Vis Exp. 2019 Jul 24;(149): Authors: Yang D Abstract The fruit fly, Drosophila melanogaster, is widely used both in biological research and biology education. Handling adult flies is common but difficult in practice, as adult flies fly. Demonstrated here is how to make some simple and cost-effective tools to address difficult issues in the handling of Drosophila. Holes...
Journal of visualized experiments : JoVE,http://www.jove.com/
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In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy.
Related ArticlesIn Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy. J Vis Exp. 2019 Jul 29;(149): Authors: Sweeney AM, Plá V, Du T, Liu G, Sun Q, Peng S, Plog BA, Kress BT, Wang X, Mestre H, Nedergaard M Abstract Cerebrospinal fluid (CSF) flow in rodents has largely been studied using ex vivo quantification of tracers. Techniques such as two-photon microscopy and magnetic resonance imaging (MRI)...
Journal of visualized experiments : JoVE,http://www.jove.com/
1d
In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones.
Related ArticlesIn Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones. J Vis Exp. 2019 Jul 25;(149): Authors: Masclef L, Maxime U, Ahmed O, Sen Nkwe N, Barbour H, Iannantuono NVG, Boubekeur A, Daou S, Affar EB Abstract Ubiquitination is a post-translational modification that plays important roles in various signaling pathways and is notably involved in the coordination of chromatin function and DNA-associated processes. This modification...
Journal of visualized experiments : JoVE,http://www.jove.com/
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Assaying Circuit Specific Regulation of Adult Hippocampal Neural Precursor Cells.
Related ArticlesAssaying Circuit Specific Regulation of Adult Hippocampal Neural Precursor Cells. J Vis Exp. 2019 Jul 24;(149): Authors: Quintanilla LJ, Yeh CY, Bao H, Catavero C, Song J Abstract Adult neurogenesis is a dynamic process by which newly activated neural stem cells (NSCs) in the subgranular zone (SGZ) of the dentate gyrus (DG) generate new neurons, which integrate into an existing neural circuit and contribute to specific hippocampal functions....
Journal of visualized experiments : JoVE,http://www.jove.com/
1d
Using Caenorhabditis elegans for Studying Trans- and Multi-Generational Effects of Toxicants.
Related ArticlesUsing Caenorhabditis elegans for Studying Trans- and Multi-Generational Effects of Toxicants. J Vis Exp. 2019 Jul 29;(149): Authors: Li Z, Ai F, Zhang J, Yu Z, Yin D Abstract Information about toxicities of chemicals are essential in their application and waste management. For chemicals at low concentrations, the long-term effects are very important in judging their consequences in the environment and on human health. In demonstrating...
Journal of visualized experiments : JoVE,http://www.jove.com/
1d
Studying Normal Tissue Radiation Effects using Extracellular Matrix Hydrogels.
Related ArticlesStudying Normal Tissue Radiation Effects using Extracellular Matrix Hydrogels. J Vis Exp. 2019 Jul 24;(149): Authors: Alves SM, Zhu T, Shostak A, Rossen NS, Rafat M Abstract Radiation is a therapy for patients with triple negative breast cancer. The effect of radiation on the extracellular matrix (ECM) of healthy breast tissue and its role in local recurrence at the primary tumor site are unknown. Here we present a method for the decellularization,...
Journal of visualized experiments : JoVE,http://www.jove.com/
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Isolation of Atrial Myocytes from Adult Mice.
Related ArticlesIsolation of Atrial Myocytes from Adult Mice. J Vis Exp. 2019 Jul 25;(149): Authors: Jansen HJ, Rose RA Abstract The electrophysiological properties of atrial myocytes importantly affect overall cardiac function. Alterations in the underlying ionic currents responsible for the action potential can cause pro-arrhythmic substrates that underlie arrhythmias, such as atrial fibrillation, which are highly prevalent in many conditions and disease...
Journal of visualized experiments : JoVE,http://www.jove.com/
1d
upper respiratory tract infection; +23 new citations
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/08/15PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Upper respiratory tract infection
16h
upper respiratory tract infection; +23 new citations
23 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/08/15PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Upper respiratory tract infection
18h
upper respiratory tract infection; +108 new citations
108 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/08/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Upper respiratory tract infection
1d
upper respiratory tract infection; +108 new citations
108 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/08/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Upper respiratory tract infection
1d
Feasibility of an ultrasound-guided approach to radiofrequency ablation of the superolateral, superomedial and inferomedial genicular nerves: a cadaveric study.
Related ArticlesFeasibility of an ultrasound-guided approach to radiofrequency ablation of the superolateral, superomedial and inferomedial genicular nerves: a cadaveric study. Reg Anesth Pain Med. 2019 Aug 12;: Authors: Vanneste B, Tomlinson J, Desmet M, Krol A Abstract INTRODUCTION: Genicular nerve radiofrequency (RF)denervation appears to be a promising treatment for knee pain in patients with degenerative osteoarthritis of the knee, when candidates...
anesth pain med
17h
Letter to the editor: Pending challenges in passenger contact tracing in air transport - a German perspective.
Related ArticlesLetter to the editor: Pending challenges in passenger contact tracing in air transport - a German perspective. Euro Surveill. 2019 Aug;24(32): Authors: Seidel J, Matysiak-Klose D, Jeglitza M, Litzba N PMID: 31411136 [PubMed - in process]
Institut de veille sanitaire (France) Communicable Disease Surveillance Centre (Great Britain) European Centre for Disease Prevention and Control,http://www.ncbi.nlm.nih.gov/entrez/eutils/erss.cgi?rss
18h
National point prevalence survey on healthcare-associated infections in acute care hospitals, Switzerland, 2017.
Related ArticlesNational point prevalence survey on healthcare-associated infections in acute care hospitals, Switzerland, 2017. Euro Surveill. 2019 Aug;24(32): Authors: Zingg W, Metsini A, Balmelli C, Neofytos D, Behnke M, Gardiol C, Widmer A, Pittet D, On Behalf Of The Swissnoso Network Abstract BackgroundAs a part of the national strategy on the prevention of healthcare-associated infections (HAI), a point prevalence survey (PPS) was conducted in...
Institut de veille sanitaire (France) Communicable Disease Surveillance Centre (Great Britain) European Centre for Disease Prevention and Control,http://www.ncbi.nlm.nih.gov/entrez/eutils/erss.cgi?rss
18h
Molecular and epidemiological characteristics of human Puumala and Dobrava-Belgrade hantavirus infections, Germany, 2001 to 2017.
Related ArticlesMolecular and epidemiological characteristics of human Puumala and Dobrava-Belgrade hantavirus infections, Germany, 2001 to 2017. Euro Surveill. 2019 Aug;24(32): Authors: Faber M, Krüger DH, Auste B, Stark K, Hofmann J, Weiss S Abstract IntroductionTwo hantavirus species, Puumala (PUUV) and Dobrava-Belgrade (DOBV) virus (genotype Kurkino), are endemic in Germany. Recent PUUV outbreaks raised questions concerning increasing frequency of...
Institut de veille sanitaire (France) Communicable Disease Surveillance Centre (Great Britain) European Centre for Disease Prevention and Control,http://www.ncbi.nlm.nih.gov/entrez/eutils/erss.cgi?rss
18h
Urban brown rats (Rattus norvegicus) as possible source of multidrug-resistant Enterobacteriaceae and meticillin-resistant Staphylococcus spp., Vienna, Austria, 2016 and 2017.
Related ArticlesUrban brown rats (Rattus norvegicus) as possible source of multidrug-resistant Enterobacteriaceae and meticillin-resistant Staphylococcus spp., Vienna, Austria, 2016 and 2017. Euro Surveill. 2019 Aug;24(32): Authors: Desvars-Larrive A, Ruppitsch W, Lepuschitz S, Szostak MP, Spergser J, Feßler AT, Schwarz S, Monecke S, Ehricht R, Walzer C, Loncaric I Abstract BackgroundBrown rats (Rattus norvegicus) are an important wildlife species in...
Institut de veille sanitaire (France) Communicable Disease Surveillance Centre (Great Britain) European Centre for Disease Prevention and Control,http://www.ncbi.nlm.nih.gov/entrez/eutils/erss.cgi?rss
18h
PTH immunoassay interference due to human anti-mouse antibodies in an obese subject with normal parathyroid function.
Related ArticlesPTH immunoassay interference due to human anti-mouse antibodies in an obese subject with normal parathyroid function. J Clin Endocrinol Metab. 2019 Aug 14;: Authors: Laudes M, Frohnert J, Ivanova K, Wandinger KP Abstract CONTEXT: Immunoassay interference is most often found for Prolactin measurement. Only few data exist on immunoassay interference for other hormones. CASE DESCRIPTION: A 36 years old obese female subject (BMI...
American Goiter Association
18h

Hepatic Fatty Acid Balance and Hepatic Fat Content in Severely Obese Humans.
Hepatic Fatty Acid Balance and Hepatic Fat Content in Severely Obese Humans. J Clin Endocrinol Metab. 2019 Aug 13;: Authors: Lytle KA, Bush NC, Triay JM, Kellogg TA, Kendrick ML, Swain JM, Gathaiya NW, Hames KC, Jensen MD Abstract PURPOSE: Nonalcoholic fatty liver disease can lead to hepatic inflammation/damage. Understanding the physiological mechanisms that contribute to excess hepatic lipid accumulation may help identify effective treatments. ...
American Goiter Association
1d
Sex hormone phenotypes in young girls and the age at pubertal milestones.
Sex hormone phenotypes in young girls and the age at pubertal milestones. J Clin Endocrinol Metab. 2019 Aug 13;: Authors: Fassler CS, Gutmark-Little I, Xie C, Giannini CM, Chandler DW, Biro FM, Pinney SM Abstract CONTEXT: The age of pubertal onset is influenced by many variables in young girls. Previous studies have not examined sex hormones longitudinally around the time of breast development and their relationship to pubertal onset. OBJECTIVE:...
American Goiter Association
1d
Maternal thyroid function, use of antithyroid drugs in early pregnancy and birth defects.
Maternal thyroid function, use of antithyroid drugs in early pregnancy and birth defects. J Clin Endocrinol Metab. 2019 Aug 13;: Authors: Andersen SL, Knøsgaard L, Olsen J, Vestergaard P, Andersen S Abstract CONTEXT: Antithyroid drug (ATD) therapy in early pregnancy is associated with birth defects, but more data are needed to substantiate the risk associated with different types of ATD. Furthermore, the role of abnormal maternal thyroid function per...
American Goiter Association
1d
Letter to the Editor: "Comparison of teriparatide and denosumab in patients switching from long-term bisphosphonate use".
Letter to the Editor: "Comparison of teriparatide and denosumab in patients switching from long-term bisphosphonate use". J Clin Endocrinol Metab. 2019 Aug 13;: Authors: Sugiyama T PMID: 31408164 [PubMed - as supplied by publisher]
American Goiter Association
1d
HDL-cholesterol, its variability and the risk of diabetes : a nationwide population-based study.
HDL-cholesterol, its variability and the risk of diabetes : a nationwide population-based study. J Clin Endocrinol Metab. 2019 Aug 13;: Authors: Lee SH, Kim HS, Park YM, Kwon HS, Yoon KH, Han K, Kim MK Abstract CONTEXT: Bidirectional relationship between low HDL-cholesterol (HDL-C) and glucose intolerance is well established. Recent studies suggested an association of lipid variability with various health outcomes. OBJECTIVE: To investigate...
American Goiter Association
1d
Three Discrete Patterns of Primary Aldosteronism Lateralization in Response to Cosyntropin during Adrenal Vein Sampling.
Three Discrete Patterns of Primary Aldosteronism Lateralization in Response to Cosyntropin during Adrenal Vein Sampling. J Clin Endocrinol Metab. 2019 Aug 13;: Authors: Wannachalee T, Zhao L, Nanba K, Nanba AT, Shields JJ, Rainey WE, Auchus RJ, Turcu AF Abstract BACKGROUND: Cosyntropin (ACTH1-24) stimulation during adrenal vein (AV) sampling (AVS) enhances the confidence of successful AV cannulation and circumvents intra-procedure hormonal fluctuations....
American Goiter Association
1d
Testosterone and estrone increase from the age of 70 years; findings from the Sex Hormones in Older Women Study.
Testosterone and estrone increase from the age of 70 years; findings from the Sex Hormones in Older Women Study. J Clin Endocrinol Metab. 2019 Aug 13;: Authors: Davis SR, Bell RJ, Robinson PJ, Handelsman DJ, Gilbert T, Phung J, Desai R, Lockery JE, Woods RL, Wolfe RS, Reid CM, Nelson MR, Murray AM, McNeil JJ Abstract IMPORTANCE: There is a lack of understanding of what is normal in terms of sex steroid levels in older women. OBJECTIVE: To determine...
American Goiter Association
1d
ERRATUM FOR "Increased Incidence Rate of Hypothyroidism After Iodine Fortification in Denmark: A 20-Year Prospective Population-Based Study".
Related ArticlesERRATUM FOR "Increased Incidence Rate of Hypothyroidism After Iodine Fortification in Denmark: A 20-Year Prospective Population-Based Study". J Clin Endocrinol Metab. 2019 Aug 12;: Authors: PMID: 31403671 [PubMed - as supplied by publisher]
American Goiter Association
1d
Brain oscillatory activity and CT perfusion in hyper-acute ischemic stroke.
Related ArticlesBrain oscillatory activity and CT perfusion in hyper-acute ischemic stroke. J Clin Neurosci. 2019 Aug 10;: Authors: Stragapede L, Furlanis G, Ajčević M, Ridolfi M, Caruso P, Naccarato M, Ukmar M, Manganotti P Abstract OBJECTIVES: The combined use of perfusion neuroimaging and brain oscillatory activity may provide a better clinical picture of neurovascular coupling of the injured area in ischemic stroke. The aim is to assess stroke-related...
J Clin Neurosci
18h
Vertigo in patients with cancer: Red flag symptoms.
Related ArticlesVertigo in patients with cancer: Red flag symptoms. J Clin Neurosci. 2019 Aug 10;: Authors: Cacho-Díaz B, Salmerón-Moreno K, Mendoza-Olivas LG, Reynoso-Noverón N, Gómez-Amador JL Abstract INTRODUCTION: Vertigo is a common condition occurring in the general population and is usually self-limited. Reports studying vertigo in patients with brain metastasis (BM), are scarce. Therefore, the aim of this study was to analyze if the presence...
J Clin Neurosci
18h
Hepatic and renal functions and blood cell counts in brain tumor patients during the perioperative period.
Related ArticlesHepatic and renal functions and blood cell counts in brain tumor patients during the perioperative period. J Clin Neurosci. 2019 Aug 10;: Authors: Zhang F, Guo X, Xing B, Yang Y, Xu Z Abstract We aimed to investigate the correlations between biochemical and hematological markers and the clinical conditions of brain tumor patients before and after craniotomy. A retrospective study was conducted in 90 brain tumor patients. Age, gender,...
J Clin Neurosci
18h
Metabolic profiling of human gliomas assessed with NMR.
Related ArticlesMetabolic profiling of human gliomas assessed with NMR. J Clin Neurosci. 2019 Aug 10;: Authors: Lee JE, Jeun SS, Kim SH, Yoo CY, Baek HM, Yang SH Abstract Little is known about the underlying metabolic alterations of gliomas. The objective of this study was to analyze metabolomic profiles of gliomas diagnosed according to revised WHO classification to demonstrate metabolic signatures beyond isocitrate dehydrogenase (IDH) 1/2 mutation....
J Clin Neurosci
18h
Predicting extended operative time and length of inpatient stay in cervical deformity corrective surgery.
Related ArticlesPredicting extended operative time and length of inpatient stay in cervical deformity corrective surgery. J Clin Neurosci. 2019 Aug 08;: Authors: Horn SR, Passias PG, Bortz CA, Pierce KE, Lafage V, Lafage R, Brown AE, Alas H, Smith JS, Line B, Deviren V, Mundis GM, Kelly MP, Kim HJ, Protopsaltis T, Daniels AH, Klineberg EO, Burton DC, Hart RA, Schwab FJ, Bess S, Shaffrey CI, Ames CP, International Spine Study Group Abstract It's increasingly...
J Clin Neurosci
1d
Pituitary abscess following endoscopic endonasal drainage of a suprasellar arachnoid cyst: Case report and review of the literature.
Related ArticlesPituitary abscess following endoscopic endonasal drainage of a suprasellar arachnoid cyst: Case report and review of the literature. J Clin Neurosci. 2019 Aug 08;: Authors: Ovenden CD, Almeida JP, Oswari S, Gentili F Abstract BACKGROUND: Arachnoid cysts are uncommon lesions of the sellar region, and only rarely require decompressive surgery to treat symptoms. Pituitary abscesses are another rare lesion, and are an uncommon complication...
J Clin Neurosci
1d
Paediatric acute lymphoblastic leukaemia causing acute leukaemic occlusion of the proximal middle cerebral artery: Treatment with endovascular thrombectomy.
Related ArticlesPaediatric acute lymphoblastic leukaemia causing acute leukaemic occlusion of the proximal middle cerebral artery: Treatment with endovascular thrombectomy. J Clin Neurosci. 2019 Aug 08;: Authors: Mahadevan J, Bacchi S, Kiley M, Moore L, Manudhane R, Pal M, Scroop R, Kleinig T Abstract Optimal treatment for ischaemic stroke in paediatric acute lymphoblastic leukaemia (ALL) is unclear. We describe an ischaemic stroke in an adolescent with...
J Clin Neurosci
1d
Modeling stimulus-dependent variability improves decoding of population neural responses.
Related ArticlesModeling stimulus-dependent variability improves decoding of population neural responses. J Neural Eng. 2019 Aug 12;: Authors: Ghanbari A, Lee CM, Read HL, Stevenson IH Abstract Neural responses to repeated presentations of an identical stimulus often show substantial trial-to-trial variability. How the mean firing rate varies in response to different stimuli or during different movements (tuning curves) has been extensively modeled in...
J Neural Eng
1d
[Immunodeficiency in chronic rhinosinusitis : An important and often underestimated cause].
[Immunodeficiency in chronic rhinosinusitis : An important and often underestimated cause]. HNO. 2019 Aug 12;: Authors: Klimek L, Chaker A, Matthias C, Sperl A, Gevaert P, Hellings P, Wollenberg B, Koennecke M, Hagemann J, Eckrich J, Becker S Abstract BACKGROUND: Chronic rhinosinusitis (CRS) is one of the most frequent chronic diseases. Among these patients the prevalence of immune defects is higher than in the healthy general population. METHODS:...
Rhinologie
1d
Acceleration of Diabetic Wound Healing with PHD2- and miR-210-Targeting Oligonucleotides.
Related ArticlesAcceleration of Diabetic Wound Healing with PHD2- and miR-210-Targeting Oligonucleotides. Tissue Eng Part A. 2019 01;25(1-2):44-54 Authors: Dallas A, Trotsyuk A, Ilves H, Bonham CA, Rodrigues M, Engel K, Barrera JA, Kosaric N, Stern-Buchbinder ZA, White A, Mandell KJ, Hammond PT, Mansbridge J, Jayasena S, Gurtner GC, Johnston BH Abstract In diabetes-associated chronic wounds, the normal response to hypoxia is impaired and many cellular...
Hypoxia-inducible factors
1d
Oxidative stress promotes ventilator-induced lung injury through activating NLRP3 inflammasome and TRPM2 channel.
Related ArticlesOxidative stress promotes ventilator-induced lung injury through activating NLRP3 inflammasome and TRPM2 channel. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3448-3455 Authors: An X, Sun X, Yang X, Liu D, Hou Y, Chen H, Wu J Abstract Ventilator has been widely used for life support, but ventilator-induced lung injury (VILI) is still a major problem. Oxidative stress has been considered as a key contributor for VILI, but the specific...
Artificial Cells, Nanomedicine, and Biotechnology
18h
Towards osteogenic differentiation of human dental pulp stem cells on PCL-PEG-PCL/zeolite nanofibrous scaffolds.
Related ArticlesTowards osteogenic differentiation of human dental pulp stem cells on PCL-PEG-PCL/zeolite nanofibrous scaffolds. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3431-3437 Authors: Alipour M, Aghazadeh M, Akbarzadeh A, Vafajoo Z, Aghazadeh Z, Raeisdasteh Hokmabad V Abstract Presently, tissue engineering has been developed as an effective option in the restoration and repair of tissue defects. One of the tissue engineering strategies is...
Artificial Cells, Nanomedicine, and Biotechnology
18h

A novel strategy to the formulation of carmustine and bioactive nanoparticles co-loaded PLGA biocomposite spheres for targeting drug delivery to glioma treatment and nursing care.
Related ArticlesA novel strategy to the formulation of carmustine and bioactive nanoparticles co-loaded PLGA biocomposite spheres for targeting drug delivery to glioma treatment and nursing care. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3438-3447 Authors: Yi S, Yang F, Jie C, Zhang G Abstract Gliomas are the most common brain tumors in humans. Different chemotherapeutics are available to treat gliomas. However, they are costly and pose numerous...
Artificial Cells, Nanomedicine, and Biotechnology
18h
Methylation dependent microRNA 1285-5p and sterol carrier proteins 2 in type 2 diabetes mellitus.
Methylation dependent microRNA 1285-5p and sterol carrier proteins 2 in type 2 diabetes mellitus. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3417-3422 Authors: Bai L, Li J, Panagal M, M B, Sekar D Abstract Diabetes mellitus (DM) is one of the severe metabolic diseases found in all types of people's lives in lower, middle and high income countries. It is suggested that the prevalence of diabetes is increasing in many countries and most of the cases...
Artificial Cells, Nanomedicine, and Biotechnology
1d
Circular RNA ZFR accelerates non-small cell lung cancer progression by acting as a miR-101-3p sponge to enhance CUL4B expression.
Circular RNA ZFR accelerates non-small cell lung cancer progression by acting as a miR-101-3p sponge to enhance CUL4B expression. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3410-3416 Authors: Zhang H, Wang X, Hu B, Zhang F, Wei H, Li L Abstract BACKGROUND: Non-small-cell lung carcinoma (NSCLC) is the most common type of lung cancer. Circular RNA ZFR (circZFR) is an identified circular RNA (circRNA) that is correlated with cancer progression. However,...
Artificial Cells, Nanomedicine, and Biotechnology
1d
Development of polypyrrole/collagen/nano-strontium substituted bioactive glass composite for boost sciatic nerve rejuvenation in vivo.
Related ArticlesDevelopment of polypyrrole/collagen/nano-strontium substituted bioactive glass composite for boost sciatic nerve rejuvenation in vivo. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3423-3430 Authors: Lin B, Dun G, Jin D, Du Y Abstract A novel nerve conductor made out of polypyrrole (PPY), collagen (Coll) and nano-strontium substituted bioactive glass (n-Sr@BG) (PPY/Coll/n-Sr@BG) was fabricated by electrospinning. SEM demonstrated that...
Artificial Cells, Nanomedicine, and Biotechnology
1d
Repression of lncRNA-SVUGP2 mediated by EZH2 contributes to the development of non-small cell lung cancer via brisking Wnt/β-catenin signal.
Related ArticlesRepression of lncRNA-SVUGP2 mediated by EZH2 contributes to the development of non-small cell lung cancer via brisking Wnt/β-catenin signal. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3400-3409 Authors: Wei S, Liu J, Li X, Liu X Abstract To grab the possible impact of lncRNA-SVUGP2 in the biology and process of non-small cell lung cancer (NSCLC). Sixty paired NSCLC tumour and the adjacent non-tumour lung tissues were collected for...
Artificial Cells, Nanomedicine, and Biotechnology
1d
A case-control study of dental abnormalities and dental maturity in childhood cancer survivors.
Related ArticlesA case-control study of dental abnormalities and dental maturity in childhood cancer survivors. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Jul 15;: Authors: Quispe RA, Rodrigues ACC, Buaes AMG, Capelozza ALA, Rubira CMF, Santos PSDS Abstract OBJECTIVE: The aim of this study was to evaluate dental abnormalities and dental maturity (DM) in the permanent dentition of childhood cancer survivors (CCSs) in comparison with that of healthy...
oral surg oral med
18h
Multiple adenomatoid odontogenic tumors in a patient with Schimmelpenning syndrome.
Related ArticlesMultiple adenomatoid odontogenic tumors in a patient with Schimmelpenning syndrome. Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Jun 14;: Authors: Chaves RRM, Júnior AACP, Gomes CC, de Castro WH, Gomez RS Abstract Schimmelpenning syndrome (SS) is a congenital neurocutaneous disorder characterized by the presence of linear nevus sebaceous, ophthalmic, neurologic, skeletal, urologic, and cardiovascular alterations. Oral manifestations...
oral surg oral med
1d
How I do it: combined petrosectomy.
Related ArticlesHow I do it: combined petrosectomy. Acta Neurochir (Wien). 2019 Aug 13;: Authors: Hanakita S, Watanabe K, Champagne PO, Froelich S Abstract BACKGROUND: Petroclival lesions are among the most complex to address in skull base surgery, being closely related to critical neurovascular structures and brainstem. The combined petrosectomy allows a wide exposure of large petroclival lesions with short working distance and provides multiple angles...
Skull Base
18h
Rapamycin Increases Collateral Circulation in Rodent Brain after Focal Ischemia as detected by Multiple Modality Dynamic Imaging.
Related ArticlesRapamycin Increases Collateral Circulation in Rodent Brain after Focal Ischemia as detected by Multiple Modality Dynamic Imaging. Theranostics. 2019;9(17):4923-4934 Authors: Wang J, Lin X, Mu Z, Shen F, Zhang L, Xie Q, Tang Y, Wang Y, Zhang Z, Yang GY Abstract Rationale: Brain collaterals contribute to improving ischemic stroke outcomes. However, dynamic and timely investigations of collateral blood flow and collateral restoration in...
Skull Base
18h
Endoscopically Assisted Middle Cranial Fossa Reconstruction Following Traumatic Intracranial Intrusion of the Mandibular Condyle.
Related ArticlesEndoscopically Assisted Middle Cranial Fossa Reconstruction Following Traumatic Intracranial Intrusion of the Mandibular Condyle. J Craniofac Surg. 2019 Mar/Apr;30(2):563-565 Authors: Liau I, Sambrook P, Cheng A Abstract Traumatic intracranial intrusions of the mandibular condyle are a rare injury pattern that carries significant morbid outcomes due to potential for neurological, otological, temporomandibular joint damage, or joint ankylosis....
Skull Base
18h
Surgical approaches for infratemporal fossa tumor resection: Fifteen years' experience of a single center.
Surgical approaches for infratemporal fossa tumor resection: Fifteen years' experience of a single center. Head Neck. 2019 Aug 12;: Authors: Yafit D, Duek I, Abu-Ghanem S, Ungar OJ, Wengier A, Moshe-Levyn H, Yanko-Arzi R, Zaretski A, Margalit N, Abergel A, Muhanna N, Fliss DM Abstract BACKGROUND: The aims of this study were to report our center's experience with infratemporal fossa (ITF) tumors, to review the treatment modalities and outcomes. ...
Skull Base
1d
Current Open Surgical Indications for Revascularization in Cerebral Ischemia.
Current Open Surgical Indications for Revascularization in Cerebral Ischemia. Acta Neurochir Suppl. 2020;127:195-199 Authors: Eastin MT, Chakravarthy VB, Sharafeddin F, Hoss D, Lopez-Gonzalez MA Abstract Cerebral revascularization was pioneered half a century ago. Gradual improvements in microsurgical instrumentation and training in microsurgical techniques have allowed significant changes that improved outcomes in neurosurgery, extrapolating this knowledge...
Skull Base
1d
Diverse phenotypes and endotypes of fungus balls caused by mixed bacterial colonization in chronic rhinosinusitis.
Related ArticlesDiverse phenotypes and endotypes of fungus balls caused by mixed bacterial colonization in chronic rhinosinusitis. Int Forum Allergy Rhinol. 2019 Aug 12;: Authors: Kim DK, Wi YC, Shin SJ, Kim KR, Kim DW, Cho SH Abstract BACKGROUND: The pathogenic roles of fungus and bacteria in chronic rhinosinusitis (CRS) remain unclear. Recently, we described the bacterial ball, which is distinct from the fungus ball, as an unusual phenotype of bacterial...
Skull Base
1d
Endoscopic repair of spontaneous skull base defects decreases the incidence rate of intracranial complications.
Related ArticlesEndoscopic repair of spontaneous skull base defects decreases the incidence rate of intracranial complications. Int Forum Allergy Rhinol. 2019 Aug 12;: Authors: Allensworth JJ, Rowan NR, Storck KA, Woodworth BA, Schlosser RJ Abstract BACKGROUND: Spontaneous skull base defects can result in life-threatening intracranial complications (ICCs), including meningitis and pneumocephalus. Endoscopic skull base reconstruction (ESBR) has traditionally...
Skull Base
1d
Frontal sinus "mega-trephination" in a tertiary rhinology practice.
Related ArticlesFrontal sinus "mega-trephination" in a tertiary rhinology practice. Int Forum Allergy Rhinol. 2019 Aug 12;: Authors: Geltzeiler M, Mowery A, Detwiller KY, Mace JC, Smith TL Abstract BACKGROUND: Frontal sinus trephination is traditionally performed through a small cutaneous incision and osteotomy, allowing irrigation of the frontal sinus. Utilizing the trephination osteotomy for endoscopic visualization and surgical manipulation requires...
Skull Base
1d
Intraosseous Orbital Cavernous Hemangioma with Frontal Extension and Dural Involvement.
Related ArticlesIntraosseous Orbital Cavernous Hemangioma with Frontal Extension and Dural Involvement. Cureus. 2019 Jun 04;11(6):e4823 Authors: Akhter AS, El Tecle N, Alexopoulos G, Espinoza G, Coppens J Abstract Primary intraosseous cavernous hemangiomas are rare skull lesions that are not typically known to involve the orbital bones or the dura. We describe a rare case of a fronto-orbital bone cavernous hemangioma with extension into the dura. A 68-year-old...
Skull Base
1d
Morphometry of organization of middle meningeal artery through the analysis of bony canal in human's skull: A clinico-anatomical and embryological insight.
Related ArticlesMorphometry of organization of middle meningeal artery through the analysis of bony canal in human's skull: A clinico-anatomical and embryological insight. J Craniovertebr Junction Spine. 2019 Apr-Jun;10(2):127-130 Authors: Honnegowda TM, Dineshan V, Kumar A Abstract Background: Middle meningeal artery (MMA) is the largest branch of the maxillary artery supplying meninges of the cranial cavity. The complexity of MMA development gives...
Skull Base
1d
Epidemiology and short-term surgical outcomes of children presenting with cerebellar tumors.
Related ArticlesEpidemiology and short-term surgical outcomes of children presenting with cerebellar tumors. Clin Neurol Neurosurg. 2018 05;168:97-101 Authors: Totapally BR, Shah AH, Niazi T Abstract OBJECTIVE: Posterior fossa tumor surgery in children poses a significant morbidity and mortality. Large multi-institutional datasets characterizing the epidemiology and morbidity of children undergoing posterior fossa tumor surgery are lacking. The objective...
Skull Base
1d

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