Tumor. Year 2019 Issue 06 is now available on CAOD.

In this issue: Effects of lymphoma cell-derived exosomes on malignant biological behaviors of human lymphoma cells (淋巴瘤细胞来源性的外泌体对人淋巴瘤细胞恶性生物学行为的影响) ZHANG Shuxian, ,XU Biyu, ,JIAN Chenglian, ,YE Fen, ,XIAO Fei, ,HAN Xiaofeng, ,HUANG Honghui, ,HOU Jian, ,WANG Ting, ,Department of Hematology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, ,Department of Hematology, Dongguan People’s Hospital, , ...... page:427-438 CD44v16 contributes to chemoresistance via the modulation of autophagy in breast cancer MCF7 cells (CD44v16通过细胞自噬途径增强乳腺癌MCF7细胞的化疗耐药性) QIAN Fuyanwen, ,FENG Fan, ,XU Wenlin, ,Central Laboratory, Fourth People’s Hospital Affiliated to Jiangsu University, ,Clinical Medicine Research Office, Medicine School of Jiangsu University, , ...... page:439-449 Dihydrotanshinone Ⅰ inhibits proliferation, migration and invasion of human osteosarcoma 143B cells and promotes apoptosis (二氢丹参酮Ⅰ抑制人骨肉瘤143B细胞的增殖、迁移和侵袭并促进其凋亡) TAN Tao, ,WANG Nan, ,LIN Duanyang, ,YANG Shengdong, ,LIN Hao, ,DENG Zhongqi, ,LUO Jinyong, ,LUO Xiaoji, ,Department of Orthopaedics, First Affiliated Hospital of Chongqing Medical University, ,Key Laboratory of Clinical Diagnostics Founded by Ministry of Education, College of Laboratory Medicine,Chongqing Medical University, , ...... page:450-459 Silencing ACLY gene inhibits migration and invasion of colon cancer HCT116 cells (沉默ACLY基因可抑制结肠癌HCT116细胞的迁移和侵袭) WEN Jun, ,MIN Xuejie, ,ZHAO Li, ,TANG Dewei, ,LIU Jianjun, ,HUANG Gang, ,ZHAO Xiaoping, ,Department of Nuclear Medicine, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, ,Department of Oncology, The First Affiliated Hospital of Nanyang Medical College, ,Shanghai University of Medicine and Health Sciences, , ...... page:460-468 Clinical efficacy of bevacizumab combined with chemotherapy in the treatment of HER2 negative metastatic breast cancer (贝伐单抗联合化疗治疗HER2阴性晚期乳腺癌的疗效分析) LIU Yaxin, ,ZHANG Jiayang, ,HUANG Wenfa, ,SHAO Bin, ,RAN Ran, ,KONG Weiyao, ,LIU Xiaoran, ,LI Kun, ,ZHANG Ruyan, ,YAN Ying, ,SONG Guohong, ,DI Lijun, ,JIANG Hanfang, ,LI Huiping, ,Key Laborator y of Carcinogenesis and Translational Research (Ministry of Education),Department of Breast Oncology, Peking University Cancer & Institute, , ...... page:469-476 Expression of Opa interacting protein 5 in gastric cancer tissues and its clinical significance (胃癌中Opa相互作用蛋白5的表达及其临床意义) WEI Wei, ,ZHANG Xiao, ,WANG Yi, ,Department of Medical Oncology, Shanghai Punan Hospital of Pudong New District, ,Department of Medical Oncology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, ,State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, ,Department of Medical Oncology,Shanghai General Hospital, Shanghai Jiao Tong University, , ...... page:477-483 Sensitivities and impact factors of biopsy choices in diagnosis of ductal carcinoma in situ : A single-center report (单中心回顾性分析乳腺导管原位癌患者活检方式的敏感度及影响其选择的相关因素) SI Jing, ,QUAN Chenlian, ,GUO Rong, ,YANG Benlong, ,CHEN Jiajian, ,WU Jiong, ,Department of Breast Surgery, Fudan University Shanghai Cancer Center, ,Collaborative Innovation Center for Cancer Medicine, Fudan University Shanghai Cancer Center, , ...... page:484-492 Challenges and strategies for chimeric antigen receptor T cell immunotherapy (嵌合抗原受体T细胞治疗面临的挑战与对策) DONG Yiwei, ,JIANG Hua, ,State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital,Shanghai Jiao Tong University School of Medicine, , ...... page:493-499+507 Molecular biomarkers for prognosis of hepatocellular carcinoma (肝癌预后相关生物标志物) TANG Wenhua, ,LIU Sunfang, ,CHEN Fuping, ,CHEN Xiuqiong, ,ZHOU Yangmei, ,LONG Guoxian, ,Department of Oncology, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, , ...... page:500-507 Mechanism and application prospects of Toll-like receptor in cancer therapy (Toll样受体在肿瘤治疗中的作用机制及应用前景) LIU Caiqi, ,HAN Ci, ,ZHANG Dekai, ,Department of Gastroenterology, Second Affiliated Hospital of Harbin Medical University, , ...... page:508-514