Publication date: Available online 8 September 2019Source: Archives of Oral BiologyAuthor(s): Hélène Brignot, Gilles FeronAbstractObjectivesThis systematic literature review aims to summarize the existing scientific evidence on the association of oral lipolysis with diet and with the perception and digestion of lipids in humans and rodents.MethodsA validated search strategy of two databases (PubMed and ISI Web of Knowledge) was carried out and the contents were screened by two independent reviewers....
Mon Sep 09, 2019 18:38
Abstract Background Although performance of the Nordic hamstring exercise (NHE) has been shown to elicit adaptations that may reduce hamstring strain injury (HSI) risk and occurrence, compliance in NHE interventions in professional soccer teams is low despite a high occurrence of HSI in soccer. A possible reason for low compliance is the high dosages prescribed within the recommended interventions. The aim of this review was to investigate...
Mon Sep 09, 2019 03:00
First Key Point, sentence 2, which previously read:
Mon Sep 09, 2019 03:00
Abstract In combat sports, athletes continuously co-adapt their behavior to that of the opponent. We consider this interactive aspect of combat to be at the heart of skilled performance, yet combat sports research often neglects or limits interaction between combatants. To promote a more interactive approach, the aim of this paper is to understand combat sports from the combined perspective of ecological psychology and dynamic systems. Accordingly, combat athletes are driven by...
Mon Sep 09, 2019 03:00
Abstract Immunotherapy with checkpoint inhibitors revolutionized melanoma treatment in both the adjuvant and metastatic setting, yet not all metastatic patients respond, and metastatic disease still often recurs among immunotherapy-treated patients with locally advanced disease. TNFSF4 is a co-stimulatory checkpoint protein expressed by several types of immune and non-immune cells, and was shown in the past to enhance the anti-neoplastic activity of T cells. Here, we assessed its...
Mon Sep 09, 2019 03:00
Following publication of the original article [1], the authors opted to correct the following reference on page 3:
Sat Sep 07, 2019 03:00
Researchers in Daegu Gyeongbuk Institute of Science and Technology in South Korea have developed biodegradable microrobots that can be magnetically controlled to deliver drugs and provide hyperthermia treatment at the site of a tumor. This latest research effort attempts to provide a delivery option for two different therapy pypes by creating biodegradable microrobots that can be activated when they are in the vicinity of a tumor. The microrobots consist of a biodegradable polymer loaded with...
Mon Sep 09, 2019 18:17
For people with hearing loss, use of a mobile or smartphone can be challenging and with limited options. While Bluetooth-connected hearing devices are available, these solutions impose a significant energy requirement that drains battery life. Most available Bluetooth hearing devices today do not allow users to have access to their mobile device for an entire day without requiring a recharge. For the past few years, Apple has offered the company’s users with hearing loss connectivity by directing...
Mon Sep 09, 2019 17:33
Researchers at Harvard have developed a way to 3D print vascular channels in large matrices composed of stem cell-derived organ building blocks. The technique could pave the way for 3D-printed organs. Living embryoid bodies surround a hollow vascular channel printed using the SWIFT method. Creating human organs using 3D printing would help to address the current shortfall in available transplants. However, to date, this has proved to be pretty tricky. One of the major stumbling...
Mon Sep 09, 2019 16:56
Nature Chemistry, Published online: 09 September 2019; doi:10.1038/s41557-019-0323-9Polytheonamides are potently cytotoxic hypermodified ribosomal peptides that are produced by an uncultivated bacterium. Now, a bioinformatic mining strategy has enabled the development of a bacterial production host that can be cultivated in a laboratory. The host generates polytheonamide-like compounds within 2 days, and can efficiently introduce multiple d-amino acids, asparagine N-methylations and C-methyl groups...
Mon Sep 09, 2019 03:00
Abstract Purpose Gigantomastia refers to pathological breast enlargement usually occurring in the peripubertal or peripartum period. Idiopathic gigantomastia, however, is a rare entity with hypotheses citing local expression of hormones and growth factors in causing this disease, none of which have been systemically analysed. The purpose of this study was to delve deeper into the mechanistic pathways causing this condition. ...
Mon Sep 09, 2019 03:00
Abstract One of the sequelae of head and neck cancer treatment is secondary lymphedema, with important impact on breathing, swallowing and vocal functions. The aim of the study was to assess the presence, staging characteristics and relationship of external and internal lymphedema and dysphagia after head and neck cancer treatment. The MDACC Lymphedema Rating Scale in Head and Neck Cancer was employed for the assessment and staging of face and neck lymphedema; the Radiotherapy...
Mon Sep 09, 2019 03:00
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Xinyu Li, Yong Zhou, Yongshuang Li, Liang Yang, Yingbo Ma, Xueqiang Peng, Shuo Yang, Jingang Liu, Hangyu LiAbstractThe success of targeted drug therapy for cancer patients has attracted extensive attention from academia and society. However, the rapid development of acquired drug resistance is becoming a major challenge. Autophagy, as an essential homeostatic and catabolic process, is crucial for the degradation...
Mon Sep 09, 2019 17:47
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Qifang Liu, Lidan Liu, Hongmei Liu, Jingjing Jiang, Shanbin Guo, Cong Wang, Yi Jia, Yue TianAbstractAimsPost-operative cognitive dysfunction (POCD) occurs after major surgery in elderly patients and affects the quality of patients’ lives. The present study aims to explore the protective effects and possible mechanisms of compound K in old mice with POCD caused by partial hepatectomy.MethodsSixteen month-old...
Mon Sep 09, 2019 17:47
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Jiaping Zheng, Jun Luo, Hui Zeng, Liwen Guo, Guoliang ShaoAbstractObjectivesIodine-125 (125I) irradiation has been widely applied in the treatment of advanced multiple malignant tumors. However, the underlying mechanism of 125I exerted an anti-tumor effect on hepatocellular carcinoma (HCC) was largely unknown.MethodsIn both HCCLM3 and SMMC-7721 cells, the effect of 125I irradiation on the glycolysis was...
Mon Sep 09, 2019 17:47
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Chu Zhang, Jie Liu, Yang Zhang, Chengyan Luo, Tong Zhu, Rongrong Zhang, Ruiqin YaoAbstractBackgroundIn recent years, a large number of studies have shown that differentially expressed lncRNAs in tumors are capable of inducing tumorigenesis and promoting tumor development. However, the role of LINC01210 in OC still remains unclear.MethodsRelative levels of LINC01210 and KLF4 in OC tissues containing in the...
Mon Sep 09, 2019 17:47
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Honghua Yue, Weitao Liang, Jun Gu, Xueshan Zhao, Tailong Zhang, Xiaoli Qin, Guonian Zhu, Zhong WuAbstractIn recent years, colchicine has been used to reduce the risk of cardiovascular events; in particular, it has been effectively used for the treatment of atrial fibrillation (AF). We first discovered that colchicine can treat AF in a rat model and that it can reverse the effects of atrial fibrosis. To...
Mon Sep 09, 2019 17:47
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Luiz Philippe da Silva Sergio, Andre Luiz Mencalha, Adenilson de Souza da Fonseca, Flavia de PaoliAbstractAcute pulmonary injury, or acute respiratory distress syndrome, has a high incidence in elderly individuals and high mortality in its most severe degree, becoming a challenge to public health due to pathophysiological complications and increased economic burden. Acute pulmonary injury can develop from...
Mon Sep 09, 2019 17:47
Publication date: November 2019Source: Biomedicine & Pharmacotherapy, Volume 119Author(s): Shangwen Liu, Yadong Wang, Wengang Li, Shaolong Yu, Zhipeng Wen, Zhifeng Chen, Feng LinAbstractBackgroundRenal cell carcinoma(RCC) is one of the most common malignancies in kidney, and usually leads to poor prognosis. Therefore, identifying novel biomarkers for predicting the progression and prognosis of RCC is essential. The purpose of this study is aimed to evaluate the function of miR-221-5p in RCC and...
Mon Sep 09, 2019 17:47
Abstract A novel in‐office and minimally‐invasive ossicular chain reconstruction using hydroxyapatite bone cement between the incus and stapes is demonstrated. Better adhesion between the cement and the bones was attained via partly removing the mucosa on the incus and stapes capitulum as well as preserving the fibrous band between the incus and stapes. This case is a proof of concept, with audiometric improvements in both 2‐month and 6‐month follow‐up periods, especially for selected patients...
Mon Sep 09, 2019 15:57
Abstract The present study aimed to identify and compare the microbial signatures between periodontally healthy and periodontitis subjects using 454 sequences of 16S rRNA genes. Subgingival plaque samples were collected from ten periodontally healthy subjects and ten matched chronic periodontitis patients. Bacterial DNA was extracted and next-generation sequencing of 16S rRNA genes was performed. The microbial composition differed between healthy subjects and periodontitis patients...
Mon Sep 09, 2019 03:00
Cancers, Vol. 11, Pages 1336: XIAP as a Target of New Small Organic Natural Molecules Inducing Human Cancer Cell Death Cancers doi: 10.3390/cancers11091336 Authors: Muñoz Brucoli Zecchini Sandoval-Hernandez Arboleda Lopez-Vallejo Delgado Giovarelli Coazzoli Catalani De Palma Perrotta Cuca Clementi Cervia X-linked inhibitor of apoptosis protein (XIAP) is an emerging crucial therapeutic target in cancer. We report on the discovery...
Mon Sep 09, 2019 03:00
Cancers, Vol. 11, Pages 1335: Genetically Engineered Mouse Models of Gliomas: Technological Developments for Translational Discoveries Cancers doi: 10.3390/cancers11091335 Authors: Imran Noorani The most common brain tumours, gliomas, have significant morbidity. Detailed biological and genetic understanding of these tumours is needed in order to devise effective, rational therapies. In an era generating unprecedented quantities of genomic sequencing data from human cancers, complementary...
Mon Sep 09, 2019 03:00
Cancers, Vol. 11, Pages 1334: Triple-Negative Breast Cancer: Current Understanding and Future Therapeutic Breakthrough Targeting Cancer Stemness Cancers doi: 10.3390/cancers11091334 Authors: Kha-Liang Lee Yung-Che Kuo Yuan-Soon Ho Yen-Hua Huang Triple-negative breast cancer (TNBC) is cancer that tested as negative for estrogen receptors (ER), progesterone receptors (PR), and excess human epidermal growth factor receptor 2 (HER2) protein which accounts for 15%–20% of...
Mon Sep 09, 2019 03:00
Abstract Alcohol is mainly consumed in social settings, in which people often adapt their drinking behavior to that of others, also called imitation of drinking. Yet, it remains unclear what drives this drinking in a social setting. In this study, we expected to see stronger brain and behavioral responses to social compared to non‐social alcohol cues, that would be associated with drinking in a social setting. The sample consisted of 153 beer‐drinking males, aged 18‐25 years. Brain responses to...
Mon Sep 09, 2019 16:26
Abstract Background Chromobox protein homolog 3 (CBX3) is one of the heterochromatin protein 1 (HP1) family members. Among multiple cancers, it is usually overexpressed. However, the mechanism and function of CBX3 in glioma remain incompletely illustrated. Methods The expression level of CBX3 as well as its correlation with glioma are detected through TCGA...
Mon Sep 09, 2019 03:00
In the original article, the names of authors Mariantonia Carosi and Tatiana Koudriavtseva were incorrectly captured, and author Francesco Cognetti's affiliation was incorrect. The information is correctly shown here.
Mon Sep 09, 2019 03:00
Abstract Purpose The purpose of this study was to determine outcomes in recurrent pediatric ependymoma. Methods We performed a systematic review of PubMed, Embase, Web of Science and the Cochrane Library for studies reporting on survival outcomes for pediatric patients with recurrent ependymoma. We then performed a meta-analysis of all eligible results. Survival...
Mon Sep 09, 2019 03:00
Journal of Investigative Medicine High Impact Case Reports, Volume 7, Issue , January-December 2019. Acquired isolated factor VII deficiency is a rare bleeding disorder and has been reported in 31 cases. This is in contrast to congenital factor VII deficiency, which while also infrequent is the most common rare congenital bleeding disorder. Acquired isolated factor VII deficiency has been described primarily in patients with solid malignancies, sepsis, and in the presence of anti-factor VII autoantibodies....
Mon Sep 09, 2019 14:59
Crisponi/cold‐induced sweating syndrome: differential diagnosis, pathogenesis and treatment concepts
Abstract Crisponi/cold‐induced sweating syndrome (CS/CISS) is an autosomal recessive disease characterized by hyperthermia, camptodactyly, feeding and respiratory difficulties often leading to sudden death in the neonatal period. The affected individuals who survived the first critical years of life, develop cold‐induced sweating and scoliosis in early childhood. The disease is caused by variants in the CRLF1 or in the CLCF1 gene. Both proteins form a heterodimeric complex that acts on...
Mon Sep 09, 2019 14:49
Severe acute asthma (SAA) can lead to respiratory failure and can be fatal. For rational use of intravenous (IV) bronchodilators, evidence regarding the pharmacokinetics and pharmacodynamics is lacking in children. The use of a loading dose IV salbutamol is not mentioned in any international guideline, and its use varies greatly between PICUs worldwide. We describe a 17-year-old Caucasian female with SAA resulting in an out-of-hospital cardiac arrest. After basic life support and return of spontaneous...
Mon Sep 09, 2019 14:05
Publication date: Available online 8 September 2019Source: Behavioural Brain ResearchAuthor(s): Jianxing Lian, Kai Li, Jing Gao, Xiaoyue Tan, Zhuo YangAbstractCognitive impairment has been widely recognized as a central feature of depression. Legumain, a lysosomal cysteine protease, plays an important role in cancer, atherosclerosis, inflammation and other pathological conditions. Meanwhile, it has been reported that the activation of legumain aggravates the cognitive impairment in neurodegenerative...
Mon Sep 09, 2019 15:51
24 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Mon Sep 09, 2019 15:39
24 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Mon Sep 09, 2019 13:37
Publication date: Available online 9 September 2019Source: Archives of Physical Medicine and RehabilitationAuthor(s): Shannon R. Miles, Lisa A. Brenner, Dawn Neumann, Flora M. Hammond, Susan Ropacki, Xinyu Tang, Blessen C. Eapen, Austin Smith, Risa Nakase-RichardsonObjectiveExamine the relationship between staff perceived irritability, anger, and aggression (IAA) and posttraumatic stress disorder (PTSD) in veterans with traumatic brain injury (TBI) of all severity levels.DesignLongitudinal cohort...
Mon Sep 09, 2019 15:28
493 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Mon Sep 09, 2019 15:20
493 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Mon Sep 09, 2019 13:19
31 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMJ Open"[jour] These pubmed results were generated on 2019/09/09PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Mon Sep 09, 2019 15:14
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