Publication date: Available online 7 September 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Axel Largent, Anaïs Barateau, Jean-Claude Nunes, Eugenia Mylona, Joël Castelli, Caroline Lafond, Peter B. Greer, Jason A. Dowling, John Baxter, Hervé Saint-Jalmes, Oscar Acosta, Renaud de CrevoisierAbstractPurposeDeep learning methods (DLMs) have recently been proposed to generate pseudo-CT (pCT) for MRI-based dose planning. This study aims to evaluate and compare DLMs...
Sun Sep 08, 2019 17:04
Publication date: Available online 7 September 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Wee Loon Ong, Farshad Foroudi, Roger L. Milne, Jeremy L. MillarAbstractPurposeTo evaluate the use of single-fraction palliative radiotherapy (SFRT) for the management of bone metastases (BM) in Victoria, AustraliaMethods and materialsThis is a population-based cohort of cancer patients who received RT for BM between 2012 and 2017 as captured in the Victorian Radiotherapy...
Sun Sep 08, 2019 17:04
Publication date: Available online 7 September 2019Source: Medical Image AnalysisAuthor(s): Tanya Nair, Doina Precup, Douglas L. Arnold, Tal ArbelAbstractDeep learning networks have recently been shown to outperform other segmentation methods on various public, medical-image challenge datasets, particularly on metrics focused on large pathologies. For diseases such as Multiple Sclerosis (MS), however, monitoring all the focal lesions visible on MRI sequences, even very small ones, is essential for...
Sun Sep 08, 2019 15:06
Abstract We derive a variational multiscale (VMS) finite element formulation for a viscoelastic, tensor‐based blood damage model. The tensor equation is numerically stabilized by a logarithmic shape tensor description that prevents unphysical, negative eigenvalues. The resulting VMS stabilization terms for this so‐called log‐morph equation are presented together with their special numerical treatment. Results for a 2D rotating stirrer test case obtained from log‐morph simulations with both SUPG...
Sat Sep 07, 2019 21:18
Publication date: Available online 6 September 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Chien-Yu Lin, Kang-Hsing Fan, Li-Yu Lee, Chuen Hsueh, Lan Yan Yang, Shu-Hang Ng, Hung-Ming Wang, Chia-Hsun Hsieh, Chih-Hung Lin, Chung-Kan Tsao, Chung-Jan Kang, Tuan-Jen Fang, Li-Ang Lee, Shiang-Fu Huang, Kai-Ping Chang, Tzu-Chen Yen, Ze Yun Tay, Yu-Wen Wen, Shu Ru Lee, Chun-Ta LiaoAbstractPurposeThe evidence for adjuvant therapy of oral cavity squamous cell carcinoma (OCSCC)...
Sat Sep 07, 2019 15:16
Publication date: Available online 6 September 2019Source: Medical Image AnalysisAuthor(s): Zehui Lin, Shengli Li, Dong Ni, Yimei Liao, Huaxuan Wen, Jie Du, Siping Chen, Tianfu Wang, Baiying LeiAbstractIt is essential to measure anatomical parameters in prenatal ultrasound images for the growth and development of the fetus, which is highly relied on obtaining a standard plane. However, the acquisition of a standard plane is, in turn, highly subjective and depends on the clinical experience of sonographers....
Sat Sep 07, 2019 14:35
Publication date: Available online 6 September 2019Source: Medical Image AnalysisAuthor(s): Seung Yeon Shin, Soochahn Lee, Il Dong Yun, Kyoung Mu LeeAbstractWe propose a novel deep learning based system for vessel segmentation. Existing methods using CNNs have mostly relied on local appearances learned on the regular image grid, without consideration of the graphical structure of vessel shape. Effective use of the strong relationship that exists between vessel neighborhoods can help improve the vessel...
Sat Sep 07, 2019 14:35
Abstract Although fractional flow reserve (FFR) and coronary flow reserve (CFR) are both frequently used to assess the functional severity of coronary artery stenosis, discordant results of diagnosis between FFR and CFR in some patient cohorts have been reported. In the present study, a computational model was employed to quantify the impacts of various pathophysiological factors on FFR and CFR. In addition, a hyperemic myocardial ischemic index (HMIx) was proposed as a reference for comparing the...
Thu Sep 05, 2019 11:28
Obsidio Inc., a medical device company based in Columbia, South Carolina, has developed an embolic hydrogel (called a gel embolic material: GEM) designed to be delivered minimally invasively through a clinical catheter for blood vessel occlusion. Applications include controlling blood flow in vascular injuries and aneurysms, reducing tumor blood supply, and preventing abnormal blood flow between arteries and veins, such as arteriovenous malformations. Currently, the gold standard treatment...
Fri Sep 06, 2019 21:30
In recognition of Polycystic Ovary Syndrome (PCOS) Awareness Month, Flo, a digital platform for women’s health and wellbeing, has announced the successful launch of PCOS Health Assistant, a self-assessment tool to help identify the risk of PCOS. PCOS is a hormonal disorder found in women that can cause irregular periods, higher than normal levels of androgen, a male hormone, and enlarged or malfunctioning ovaries. The condition can also lead to infertility, diabetes, cardiovascular...
Fri Sep 06, 2019 20:40
SoniVie, a company based in Israel, won FDA Breakthrough Device Designation for its TIVUS intravascular ultrasound system for patients suffering from pulmonary arterial hypertension (PAH). Currently there are only medications available for PAH and even those don’t do so well at improving mortality rates, so the new designation is potentially a quick path to approval for the new technology. The TIVUS system is designed to help improve pulmonary vascular resistance by ablating...
Fri Sep 06, 2019 20:03
Clinicians in India have teamed up to demonstrate the feasibility of having a physician remotely perform percutaneous coronary intervention (PCI) procedures. Using the CorPath GRX, an FDA cleared cath lab robot that lets physicians stay away from the radiation produced by fluoroscopes, the team from the Apex Heart Institute in Ahmedabad positioned the control mechanism in a building 20 miles away from where the patients were to be treated. They were then able to perform five separate...
Fri Sep 06, 2019 18:41
Publication date: Available online 6 September 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Marloes Duijm, Noëlle C. van der Voort van Zyp, Paul van de Vaart, Esther Oomen-de Hoop, Mirjam E. Mast, Mischa S. Hoogeman, Joost J. NuyttensAbstractBackgroundThe treatment of central lung tumors with Stereotactic Body Radiotherapy (SBRT) is challenged by the risk of excessive esophageal toxicity. To improve clinical decision making we aimed to derive Normal Tissue Complication...
Fri Sep 06, 2019 13:54
Publication date: Available online 5 September 2019Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Nguyen H. Tran, Vaibhav Sahai, Kent A. Griffith, Hari Nathan, Ravi Kaza, Kyle C. Cuneo, Jiaqi Shi, Edward Kim, Christopher J. Sonnenday, Clifford S. Cho, Theodore S. Lawrence, Mark M. ZalupskiAbstractBackgroundPreoperative therapy in borderline resectable pancreatic cancer (BRPC) is intended to increase R0 resection rates. An optimal approach in BRPC is yet to be defined.MethodsPatients...
Fri Sep 06, 2019 13:54
Publication date: October 2019Source: Medical Image Analysis, Volume 57Author(s):
Fri Sep 06, 2019 13:50
Publication date: Available online 5 September 2019Source: Medical Image AnalysisAuthor(s): Tianjiao Liu, Qianqian Guo, Chunfeng Lian, Xuhua Ren, Shujun Liang, Jing Yu, Lijuan Niu, Weidong Sun, Dinggang ShenAbstractAccurate diagnosis of thyroid nodules using ultrasonography is a valuable but tough task even for experienced radiologists, considering both benign and malignant nodules have heterogeneous appearances. Computer-aided diagnosis (CAD) methods could potentially provide objective suggestions...
Fri Sep 06, 2019 13:50
Okinawa is the largest and most populated island of the Ryukyu Archipelago in southern Japan and is renowned for its natural resources and beauty. Similar as to what has been happening in the rest of the country, Okinawa Island has been affected by an increasing amount of development and construction work. The trend has been particularly acute after reversion to Japanese sovereignty in 1972, following 27 years of post-war American administration. A coastline once characterized by extended sandy beaches...
Fri Sep 06, 2019 03:00
Background Injection of adipose-derived stem cells (ASCs) is a promising treatment for facial contour deformities. However, its treatment mechanisms remain largely unknown. The study aimed to explain the molecular mechanisms of adipogenic differentiation from ASCs based on the roles of long noncoding RNAs (lncRNAs). Methods Datasets of mRNA–lncRNA (GSE113253) and miRNA (GSE72429) expression profiling were collected from Gene Expression Omnibus database. The differentially expressed genes...
Fri Sep 06, 2019 03:00
A series of novel 1,3,5-thiadiazine-2-thione derivatives containing a 1,3,4-thiadiazole group was designed and synthesized. The structures of all the compounds were well characterized using 1H NMR, 13C NMR and high-resolution mass spectrometer, and further confirmed by the X-ray diffraction analysis of 8d. The antimicrobial activities of all the target compounds against Xanthomonas oryzae pv. oryzicola, X. oryzae pv. oryzae, Rhizoctonia solani and Fusarium graminearum were evaluated. The in vitro...
Fri Sep 06, 2019 03:00
The long-term use of herbicides to remove weeds in fallow croplands can impair soil biodiversity, affect the quality of agricultural products, and threaten human health. Consequently, the identification of methods that can effectively limit the weed seed bank and maintain fallow soil fertility without causing soil pollution for the next planting is a critical task. In this study, four weeding treatments were established based on different degrees of disturbance to the topsoil: natural fallow (N),...
Fri Sep 06, 2019 03:00
Ortleppascaris sinensis is the dominant nematode species infecting the gastrointestinal tract of the captive Chinese alligator, a critically endangered species. Gastrointestinal nematode infection may cause a loss of appetite, growth, a development disorder, and even mortality in alligators, especially young ones. This research first establishment a loop-mediated isothermal amplification (LAMP) assay in rapidly identifying O. sinensis, upon the basis of the complete internal transcribed spacers (ITS)...
Fri Sep 06, 2019 03:00
Hepatocellular carcinoma (HCC) is a common yet deadly form of malignant cancer. However, the specific mechanisms involved in HCC diagnosis have not yet fully elucidated. Herein, we screened four publically available Gene Expression Omnibus (GEO) expression profiles (GSE14520, GSE29721, GSE45267 and GSE60502), and used them to identify 409 differentially expressed genes (DEGs), including 142 and 267 up- and down-regulated genes, respectively. The DAVID database was used to look for functionally enriched...
Fri Sep 06, 2019 03:00
Atmospheric nitrogen (N) deposition and phosphorus (P) addition both can change soil bacterial and fungal community structure with a consequent impact on ecosystem functions. However, which factor plays an important role in regulating responses of bacterial and fungal community to N and P enrichments remains unclear. We conducted a manipulative experiment to simulate N and P inputs (10 g N · m−2 · yr−1 NH4NO3 or 10 g P · m−2 · yr−1 NaH2PO4) and compared their effects on soil bacterial and fungal...
Fri Sep 06, 2019 03:00
Dendrobium alkaloids decrease Aβ by regulating α- and β-secretases in hippocampal neurons of SD rats
Background Alzheimer’s disease (AD) is the primary cause of dementia in the elderly. The imbalance between production and clearance of amyloid β (Aβ) is a very early, often initiating factor in AD. Dendrobium nobile Lindl. alkaloids (DNLA) extracted from a Chinese medicinal herb, which have been shown to have anti-aging effects, protected against neuronal impairment in vivo and in vitro. Moreover, we confirmed that DNLA can improve learning and memory function in elderly normal mice,...
Fri Sep 06, 2019 03:00
Due to the misuse of chemical pesticides, small green leafhoppers (Empoasca onukii Matsuda) have developed resistance to pesticides, thereby posing a serious problem to the tea industry. Glutathione S-transferases (GSTs) are an important family of enzymes that are involved in pesticide resistance in Empoasca onukii Matsuda. Empoasca onukii GST sigma 1 (EoGSTs1, GenBank: MK443501) is a member of the GST family. In this study, the full-length cDNA of EoGSTs1 was cloned by reverse transcription polymerase...
Fri Sep 06, 2019 03:00
Notodasus Fauchald, 1972 is a small genus of the polychaete family Capitellidae, including 10 described species worldwide. The genus is unusual in the Central Indo-Pacific, and there is no taxonomic record of Notodasus in this region. In this study, two new species of Notodasus are described and illustrated, namely Notodasus celebensis sp. nov. and N. chinensis sp. nov. The former species, collected from the mixed-species seagrass beds in the Indonesian island of Sulawesi, is mainly characterized...
Fri Sep 06, 2019 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου