Related ArticlesDeterminants of Inter-Individual Variability in Corticomotor Excitability Induced by Paired Associative Stimulation. Front Neurosci. 2019;13:841 Authors: Minkova L, Peter J, Abdulkadir A, Schumacher LV, Kaller CP, Nissen C, Klöppel S, Lahr J Abstract Transcranial magnetic stimulation (TMS) is a well-established tool in probing cortical plasticity in vivo. Changes in corticomotor excitability can be induced using paired associative stimulation...
Tue Sep 03, 2019 13:19
Related ArticlesBrain Structural Correlates of Odor Identification in Mild Cognitive Impairment and Alzheimer's Disease Revealed by Magnetic Resonance Imaging and a Chinese Olfactory Identification Test. Front Neurosci. 2019;13:842 Authors: Wu X, Geng Z, Zhou S, Bai T, Wei L, Ji GJ, Zhu W, Yu Y, Tian Y, Wang K Abstract Alzheimer's disease (AD) is a common memory-impairment disorder frequently accompanied by olfactory identification (OI) impairments....
Tue Sep 03, 2019 13:19
Related ArticlesRisk Factors and Neuropsychological Assessments of Subjective Cognitive Decline (plus) in Chinese Memory Clinic. Front Neurosci. 2019;13:846 Authors: Hao L, Xing Y, Li X, Mu B, Zhao W, Wang G, Wang T, Jia J, Han Y Abstract Background: Since subjective cognitive decline (SCD) was standardized in 2014, many studies have investigated its features. However, the risk of SCD (plus) progressing to AD is much higher, and yet there have been few...
Tue Sep 03, 2019 13:19
Related ArticlesInhibition of Brain Area and Functional Connectivity in Idiopathic Sudden Sensorineural Hearing Loss With Tinnitus, Based on Resting-State EEG. Front Neurosci. 2019;13:851 Authors: Cai Y, Li J, Chen Y, Chen W, Dang C, Zhao F, Li W, Chen G, Chen S, Liang M, Zheng Y Abstract This study aimed to identify the mechanism behind idiopathic sudden sensorineural hearing loss (ISSNHL) in patients with tinnitus by investigating aberrant activity...
Tue Sep 03, 2019 13:19
Related ArticlesThe Relationship Between Sleep Duration and Participation in Home, School, and Community Activities Among School-Aged Children. Front Neurosci. 2019;13:860 Authors: Chien CW, Cheung P, Chen CY Abstract Sleep duration has important implications for children's participation in daily activities; however, past attempts to examine this relationship has been limited to specific types of physical or educational activities. The present study...
Tue Sep 03, 2019 13:19
Related ArticlesPre-plaque Aß-Mediated Impairment of Synaptic Depotentiation in a Transgenic Rat Model of Alzheimer's Disease Amyloidosis. Front Neurosci. 2019;13:861 Authors: Qi Y, Klyubin I, Hu NW, Ondrejcak T, Rowan MJ Abstract How endogenously produced soluble amyloid ß-protein (Aß) affects synaptic plasticity in vulnerable circuits should provide insight into early Alzheimer's disease pathophysiology. McGill-R-Thy1-APP transgenic rats, modeling...
Tue Sep 03, 2019 13:19
Related ArticlesMRS Reveals Chronic Inflammation in T2w MRI-Negative Perilesional Cortex - A 6-Months Multimodal Imaging Follow-Up Study. Front Neurosci. 2019;13:863 Authors: Yasmin A, Pitkänen A, Jokivarsi K, Poutiainen P, Gröhn O, Immonen R Abstract Sustained inflammation in the injured cortex is a promising therapeutic target for disease-modification after traumatic brain injury (TBI). However, its extent and dynamics of expansion are incompletely...
Tue Sep 03, 2019 13:19
Related ArticlesReconciling Color Vision Models With Midget Ganglion Cell Receptive Fields. Front Neurosci. 2019;13:865 Authors: Patterson SS, Neitz M, Neitz J Abstract Midget retinal ganglion cells (RGCs) make up the majority of foveal RGCs in the primate retina. The receptive fields of midget RGCs exhibit both spectral and spatial opponency and are implicated in both color and achromatic form vision, yet the exact mechanisms linking their responses...
Tue Sep 03, 2019 13:19
Related ArticlesMicroRNA-126-3p Attenuates Intracerebral Hemorrhage-Induced Blood-Brain Barrier Disruption by Regulating VCAM-1 Expression. Front Neurosci. 2019;13:866 Authors: Fu X, Niu T, Li X Abstract Background: miR-126 is closely related to the occurrence of various complications after intracerebral hemorrhage (ICH), but the molecular mechanism is not fully elucidated. This study aimed to explore the mechanism of miR-126-3p in alleviating brain...
Tue Sep 03, 2019 13:19
Related ArticlesThe Relevance of Insulin Action in the Dopaminergic System. Front Neurosci. 2019;13:868 Authors: Fiory F, Perruolo G, Cimmino I, Cabaro S, Pignalosa FC, Miele C, Beguinot F, Formisano P, Oriente F Abstract The advances in medicine, together with lifestyle modifications, led to a rising life expectancy. Unfortunately, however, aging is accompanied by an alarming boost of age-associated chronic pathologies, including neurodegenerative and...
Tue Sep 03, 2019 13:19
Related ArticlesBulbar Problems Self-Reported by Children and Adults with Spinal Muscular Atrophy. J Neuromuscul Dis. 2019 Aug 26;: Authors: van der Heul AMB, Wijngaarde CA, Wadman RI, Asselman F, van den Aardweg MTA, Bartels B, Cuppen I, Gerrits E, van den Berg LH, van der Pol WL, van den Engel-Hoek L Abstract BACKGROUND: Spinal muscular atrophy (SMA) is hereditary motor neuron disorder, characterised by the degeneration of motor neurons and progressive...
Tue Sep 03, 2019 13:25
Related ArticlesTongue stretching exercises improve tongue motility and oromotor function in patients with dysphagia after stroke: A preliminary randomized controlled trial. Arch Oral Biol. 2019 Aug 12;108:104521 Authors: Hwang NK, Kim HH, Shim JM, Park JS Abstract OBJECTIVES: This study investigated the effect of tongue stretching exercises (TSE) on tongue motility and oromotor function in patients with dysphagia after stroke. DESIGN: This...
Tue Sep 03, 2019 13:25
Related ArticlesSupplementation of All-Trans-Retinoic Acid Below Cytotoxic Levels Promotes Adipogenesis in 3T3-L1 Cells. Lipids. 2019 01;54(1):99-107 Authors: Kim DH, Lee JW, Lee K Abstract Vitamin A, referred to as retinol, is an essential nutrient that affects the cell growth and differentiation including adipogenesis. Although previous studies using supraphysiological doses (over 1 μM) of all-trans-retinoic acid (atRA) demonstrated antiadipogenic...
Tue Sep 03, 2019 13:30
Related ArticlesRA-XII Suppresses the Development and Growth of Liver Cancer by Inhibition of Lipogenesis via SCAP-dependent SREBP Supression. Molecules. 2019 May 12;24(9): Authors: Guo D, Wang Y, Wang J, Song L, Wang Z, Mao B, Tan N Abstract Lipogenesis plays a critical role in the growth and metastasis of tumors, which is becoming an attractive target for anti-tumor drugs. RA-XII, one of the cyclopeptide glycosides isolated from Rubia yunnanensis,...
Tue Sep 03, 2019 13:30
Related ArticlesCinobufagin Promotes Cell Cycle Arrest and Apoptosis to Block Human Esophageal Squamous Cell Carcinoma Cells Growth via the p73 Signalling Pathway. Biol Pharm Bull. 2019;42(9):1500-1509 Authors: Deng X, Sheng J, Liu H, Wang N, Dai C, Wang Z, Zhang J, Zhao J, Dai E Abstract Cinobufagin isolated from traditional Chinese herbs has antitumour, anaesthetic, analgesic and anti-inflammatory effects. Recently, the antitumour activity of cinobufagin...
Tue Sep 03, 2019 13:30
Related ArticlesDNA-binding activity and cytotoxic and cell-cycle arrest properties of some new coumarin derivatives: a multispectral and computational investigation. Luminescence. 2019 Sep 02;: Authors: Khosravifar F, Dehghan G, Bidoki SK, Mahdavi M Abstract Coumarins are the most important class of natural compounds found widely in various plants. Many coumarin derivatives with different biological and pharmacological activities have been synthesized....
Tue Sep 03, 2019 13:30
Related ArticlesCombination therapies of Artemisinin and its derivatives as a viable approach for future cancer treatment. Curr Pharm Des. 2019 Sep 02;: Authors: Kumar MS, Yadav TT, Khair RR, Peters GJ, Yergeri MC Abstract BACKGROUND: Many anticancer drugs have been developed for clinical usage till now, but the major problem is the development of drug-resistance over a period of time in the treatment of cancer. Anticancer drugs produce huge adverse...
Tue Sep 03, 2019 13:30
Related ArticlesSynthesis, anticancer activity and molecular docking studies on 1,2-diarylbenzimidazole analogues as anti-tubulin agents. Bioorg Chem. 2019 Aug 26;92:103219 Authors: Zhang YL, Yang R, Xia LY, Man RJ, Chu YC, Jiang AQ, Wang ZC, Zhu HL Abstract Twenty-four 1,2-diarylbenzimidazole derivatives were designed, synthesized and biologically evaluated. It turned out that most of them were potential anticancer drugs. Among them, compound c24 showed...
Tue Sep 03, 2019 13:30
The Journal of Antibiotics, Published online: 03 September 2019; doi:10.1038/s41429-019-0232-6Inhibition of Mycobacterium abscessus, M. chelonae, and M. fortuitum biofilms by Methylobacterium sp
Tue Sep 03, 2019 03:00
Related ArticlesTargeting Mutant KRAS for Anticancer Therapy. Curr Top Med Chem. 2019 Sep 02;: Authors: Chen F, Alphonse MP, Liu Y, Liu Q Abstract Over the past decades, designing therapeutic strategies to target KRAS-mutant cancers, which is one of the most frequent mutant oncogenes among all cancer types, have proven unsuccessful regardless of many concerted attempts. There are key challenges for KRAS-mutant anticancer therapy, as the complex cellular...
Tue Sep 03, 2019 13:40
Related ArticlesRecent Advances in Developing K-Ras Plasma Membrane Localization Inhibitors. Curr Top Med Chem. 2019 Sep 02;: Authors: Ye N, Xu Q, Li W, Wang P, Zhou J Abstract The Ras proteins play an important role in cell growth, differentiation, proliferation and survival by regulating diverse signaling pathways. Oncogenic mutant K-Ras is the most frequently mutated class of Ras superfamily and highly prevalent in many human cancers. Despite intensive...
Tue Sep 03, 2019 13:40
Related ArticlesDrug Combinatorial Therapies for Treatment of KRAS Mutated Lung Cancers. Curr Top Med Chem. 2019 Sep 02;: Authors: He H, Xu C, Cheng Z, Qian X, Zheng L Abstract KRAS is the most common oncogene to be mutated in lung cancer, and therapeutics directly targeting KRAS has proven to be challenging. The mutations of KRAS are associated with poor prognosis, resistance to both adjuvant therapy and targeted EGFR TKI. The EGFR TKI provide significant...
Tue Sep 03, 2019 13:40
Related ArticlesOverexpression of Spexin 1 in the Dorsal Habenula Reduces Anxiety in Zebrafish. Front Neural Circuits. 2019;13:53 Authors: Jeong I, Kim E, Seong JY, Park HC Abstract Spexin (SPX) is an evolutionarily conserved neuropeptide that is expressed in the mammalian brain and peripheral tissue. Two orthologs are present in the teleost, SPX1 and SPX2. SPX1 is involved in reproduction and food intake. Recently, SPX1 neurons have been found to be...
Tue Sep 03, 2019 13:50
Related ArticlesAuditory and audio-vocal responses of single neurons in the monkey ventral premotor cortex. Hear Res. 2018 09;366:82-89 Authors: Hage SR Abstract Monkey vocalization is a complex behavioral pattern, which is flexibly used in audio-vocal communication. A recently proposed dual neural network model suggests that cognitive control might be involved in this behavior, originating from a frontal cortical network in the prefrontal cortex and...
Tue Sep 03, 2019 13:52
Related ArticlesIdentifying the relationship between oscillatory dynamics and event-related responses. Int J Psychophysiol. 2018 11;133:182-192 Authors: Schneider JM, Maguire MJ Abstract Event related potentials (ERPs) and time frequency analysis of the EEG can identify the temporally distinct coordination of groups of neurons across brain regions during sentence processing. Although there are strong arguments that ERP components and neural oscillations...
Tue Sep 03, 2019 13:52
Related ArticlesStimulus complexity matters when you hear your own voice: Attention effects on self-generated voice processing. Int J Psychophysiol. 2018 11;133:66-78 Authors: Conde T, Gonçalves ÓF, Pinheiro AP Abstract The ability to discriminate self- and non-self voice cues is a fundamental aspect of self-awareness and subserves self-monitoring during verbal communication. Nonetheless, the neurofunctional underpinnings of self-voice perception and...
Tue Sep 03, 2019 13:52
Related ArticlesGender effects on auditory P300: A systematic review. Int J Psychophysiol. 2018 11;133:55-65 Authors: Melynyte S, Wang GY, Griskova-Bulanova I Abstract The evidence suggests that gender-related effects could influence the electrophysiological P300 parameters and stand as an additional source of variation for both clinical and non-clinical subjects. The aim of this paper is to characterize gender-related differences in P300 potential...
Tue Sep 03, 2019 13:52
Related ArticlesCognitive disorders in a patient with an arachnoid cyst of the sylvian fissure and improvement after surgical treatment: Case description. Appl Neuropsychol Child. 2019 Apr-Jun;8(2):182-186 Authors: Kwiatkowska K, Hałabuda A, Rybus J, Kwiatkowski S Abstract Arachnoid cysts cause a wide spectrum of clinical symptoms. Often it is difficult to clearly establish the relation between the presence of an arachnoid cyst and problems reported...
Tue Sep 03, 2019 13:54
Related ArticlesAssessment of craniofacial hyperhidrosis and flushing by sphenopalatine blockade - a randomized trial. Rhinology. 2019 Sep 02;: Authors: Lehrer E, Nogues A, Jaume F, Mullol J, Alobid I Abstract BACKGROUND: Craniofacial hyperhidrosis (CFH) and flushing express nervous system autonomic dysfunction. Available reference treatments lack good compliance. The study objective was to investigate variations of CFH/flushing after two methods of...
Tue Sep 03, 2019 13:54
Related ArticlesA Novel Technique for Endoscopic Repair of Large Anterior Skull Base Defects: The PDS Wrap. Am J Rhinol Allergy. 2019 Sep 02;:1945892419873991 Authors: Jolly K, Okonkwo O, Tsermoulas G, Ahmed SK PMID: 31475860 [PubMed - as supplied by publisher]
Tue Sep 03, 2019 13:54
Related ArticlesEvolving strategies for resection of sellar/parasellar synchronous tumors via endoscopic endonasal approach - a technical case report and systematic review of the literature. World Neurosurg. 2019 Aug 30;: Authors: Roethlisberger M, Jayapalan RR, Hostettler IC, Kadir KABA, Mun KS, Brand Y, Mariani L, Prepageran N, Waran V Abstract BACKGROUND: Data on the endonasal endoscopic approach (EEA) to treat sellar/parasellar synchronous tumors...
Tue Sep 03, 2019 13:54
Publication date: Available online 3 September 2019Source: Annals of Diagnostic PathologyAuthor(s): Tariq N. Aladily, Ahmad T. Mansour, Randa Mahgoob, Joseph D. Khoury, Pembe Oltulu, L. Jeffrey Medeiros
Tue Sep 03, 2019 13:55
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Jinakan Aksorn, Siriwan TeepooAbstractHerein, we propose the first fabrication of a microfluidic paper-based analytical device (μPAD) as a simple, rapid and selective method for the simultaneous detection of sucrose, fructose and glucose for quality monitoring in the sugar industry. Multiplex detection of the three analytes was achieved by three detection zones designed on a single device. Each detection zone on the μPAD was modified...
Tue Sep 03, 2019 13:58
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Yanna Lin, Yuanling Sun, Yuxue Dai, Weiyan Sun, Xiaodong Zhu, Hao Liu, Rui Han, Dandan Gao, Chuannan Luo, Xueying WangAbstractA “signal-on” chemiluminescence biosensor was established for detecting thrombin. The thrombin aptamer1-functionalized magnetic sodium alginate (Malg-Apt1) hydrogel was synthesized by physical interaction between sodium alginate and Ca2+, and it was used in the biosensor for separating and enriching thrombin....
Tue Sep 03, 2019 13:58
Related ArticlesLow UBE4B expression increases sensitivity of chemoresistant neuroblastoma cells to EGFR and STAT5 inhibition. Cancer Biol Ther. 2019 Sep 01;:1-14 Authors: Memarzadeh K, Savage DJ, Bean AJ Abstract Neuroblastoma is the most common malignancy in infants. Overexpression of the epidermal growth factor receptor (EGFR) in neuroblastoma tumors underlies resistance to chemotherapeutics. UBE4B, an E3/E4 ubiquitin ligase involved in EGFR degradation,...
Tue Sep 03, 2019 14:03
Related ArticlesThe impact of non-invasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) on the diagnosis of thyroid nodules. Gland Surg. 2019 Aug;8(Suppl 2):S86-S97 Authors: Pusztaszeri M, Bongiovanni M Abstract More than 70 years ago, Prof. Pierre Masson, a renowned French-Canadian pathologist (1880-1959), advised us that "No classification is more difficult to establish than that of thyroid carcinomas…Of all cancers, they...
Tue Sep 03, 2019 14:03
Related ArticlesMotoric Recovery After Transplantation of Bone Marrow Derived Mesenchymal Stem Cells in Chronic Spinal Cord Injury: A Case Report. Am J Case Rep. 2019 Sep 02;20:1299-1304 Authors: Phedy P, Djaja YP, Gatam L, Kusnadi Y, Wirawan RP, Tobing IMS, Subakir N, Mappalilu A, Prawira MA, Yauwenas R, Gatam AR Abstract BACKGROUND For the past 20 years, numerous of clinical trials focusing on the use of mesenchymal stem cells (MSC) in spinal cord...
Tue Sep 03, 2019 14:07
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου