IJNS, Vol. 5, Pages 31: The Reliable, Automatic Classification of Neonates in First-Tier MALDI-MS Screening for Sickle Cell Disease International Journal of Neonatal Screening doi: 10.3390/ijns5030031 Authors: Marven El Osta Pierre Naubourg Olivier Grunewald Gilles Renom Patrick Ducoroy Jean Marc Périni Previous research has shown that a MALDI-MS technique can be used to screen for sickle cell disease (SCD), and that a system combining automated sample preparation, MALDI-MS...
Sat Aug 31, 2019 03:00
IJNS, Vol. 5, Pages 30: Newborn Sickle Cell and Thalassaemia Screening Programme: Automating and Enhancing the System to Evaluate the Screening Programme International Journal of Neonatal Screening doi: 10.3390/ijns5030030 Authors: Catherine Coppinger Robyn O’Loughlin Good information is needed to demonstrate that a screening programme is meeting its objectives, to measure performance against standards and to ensure that action is taken if standards are not met. In 2010, the NHS Sickle...
Sat Aug 31, 2019 03:00
IJNS, Vol. 5, Pages 29: Diagnosis of Carnitine Deficiency in Extremely Preterm Neonates Related to Parenteral Nutrition: Two Step Newborn Screening Approach International Journal of Neonatal Screening doi: 10.3390/ijns5030029 Authors: Mamatha Ramaswamy Victor Anthony Skrinska Rola Fayez Mitri Ghassan Abdoh Currently, there is no evidence in the literature to support the routine supplementation of all parenterally fed premature infants with l-carnitine. In our study, we found...
Sat Aug 31, 2019 03:00
IJNS, Vol. 5, Pages 28: A Cost-Effectiveness Analysis of Newborn Screening for Severe Combined Immunodeficiency in the UK International Journal of Neonatal Screening doi: 10.3390/ijns5030028 Authors: Alice Bessey James Chilcott Joanna Leaviss Carmen de la Cruz Ruth Wong Severe combined immunodeficiency (SCID) can be detected through newborn bloodspot screening. In the UK, the National Screening Committee (NSC) requires screening programmes to be cost-effective at standard...
Fri Aug 30, 2019 03:00
JCM, Vol. 8, Pages 1364: Transcatheter Aortic Valve Replacement Is Associated with Less Oxidative Stress and Faster Recovery of Antioxidant Capacity than Surgical Aortic Valve Replacement Journal of Clinical Medicine doi: 10.3390/jcm8091364 Authors: Anna Komosa Bartłomiej Perek Piotr Rzymski Maciej Lesiak Jolanta M. Siller-Matula Marek Grygier Mateusz Puślecki Marcin Misterski Anna Olasińska-Wiśniewska Mariola Ropacka-Lesiak Zbigniew Krasiński Przemysław Niedzielski...
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JCM, Vol. 8, Pages 1365: Towards Circulating-Tumor DNA-Based Precision Medicine Journal of Clinical Medicine doi: 10.3390/jcm8091365 Authors: Ai Hironaka-Mitsuhashi Anna Sanchez Calle Takahiro Ochiya Shin Takayama Akihiko Suto In the era of precision medicine, targeted therapies have been implemented for various diseases. Genomic information guides decision-making in cancer treatment. The improvements in next-generation sequencing and polymerase chain reaction have made it...
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JCM, Vol. 8, Pages 1363: Mitochondrial Structural Changes in the Pathogenesis of Diabetic Retinopathy Journal of Clinical Medicine doi: 10.3390/jcm8091363 Authors: Roy Kim Sankaramoorthy Abstract: At the core of proper mitochondrial functionality is the maintenance of its structure and morphology. Physical changes in mitochondrial structure alter metabolic pathways inside mitochondria, affect mitochondrial turnover, disturb mitochondrial dynamics, and promote mitochondrial fragmentation,...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1355: Pregabalin Failed to Prevent Dry Eye Symptoms after Laser-Assisted in Situ Keratomileusis (LASIK) in a Randomized Pilot Study Journal of Clinical Medicine doi: 10.3390/jcm8091355 Authors: Anat Galor Sneh Patel Leslie R. Small Adriana Rodriguez Michael J. Venincasa Stephen E. Valido William Feuer Roy C. Levitt Constantine D. Sarantopoulos Elizabeth R. Felix Purpose: Perioperative pregabalin administration has been found to reduce the...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1361: Alterations in Alzheimer’s Disease-Associated Gene Expression in Severe Obstructive Sleep Apnea Patients Journal of Clinical Medicine doi: 10.3390/jcm8091361 Authors: Hsueh-Yu Li Ming-Shao Tsai Chung-Guei Huang Robert Y. L. Wang Li-Pang Chuang Ning-Hung Chen Chi-Hung Liu Cheng-Ming Hsu Wen-Nuan Cheng Li-Ang Lee Background: Obstructive sleep apnea (OSA) increases the risk of Alzheimer’s disease (AD), and inflammation may be...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1360: Prognostic Factors for Re-Arrest with Shockable Rhythm during Target Temperature Management in Out-Of-Hospital Shockable Cardiac Arrest Patients Journal of Clinical Medicine doi: 10.3390/jcm8091360 Authors: Ryoo Lee Lee Youn Kim Kim Kim Kim Re-arrest during post-cardiac arrest care after the return of spontaneous circulation is not uncommon. However, little is known about the risk factors associated with re-arrest. A previous study...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1353: A Prospective Assessment of the Diagnostic Value of Contrast-Enhanced Ultrasound, Dynamic Computed Tomography and Magnetic Resonance Imaging for Patients with Small Liver Tumors Journal of Clinical Medicine doi: 10.3390/jcm8091353 Authors: Hsiao Chen Huang Aim: This prospective study assessed the diagnostic value of contrast-enhanced ultrasound (CEUS) using long Kupffer phase enhancement for adults with liver tumor size of less than 3 cm. Performance...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1358: Prognostic Significance of Abdominal-to-Gluteofemoral Adipose Tissue Distribution in Patients with Breast Cancer Journal of Clinical Medicine doi: 10.3390/jcm8091358 Authors: Lee Kim Lee Han Lee Lee This study aimed to evaluate the association between abdominal-to-gluteofemoral adipose tissue (AT) distribution and recurrence-free survival (RFS) in breast cancer patients. Staging F-18 fluorodexoyglucose (FDG) positron emission tomography/computed...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1356: Comparison of Percutaneous Endoscopic Surgery and Traditional Anterior Open Surgery for Treating Lumbar Infectious Spondylitis Journal of Clinical Medicine doi: 10.3390/jcm8091356 Authors: Fu Wang Lin Chang Wong Su Minimally invasive surgery is becoming popular for treating spinal disorders. The advantages of percutaneous endoscopic debridement and drainage (PEDD) for infectious spondylitis include direct observation of the lesion, direct...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1359: Significant Correlation Between Grip Strength and m2bpgi in Patients with Chronic Liver Diseases Journal of Clinical Medicine doi: 10.3390/jcm8091359 Authors: Nishikawa Enomoto Yoh Iwata Sakai Kishino Ikeda Takashima Aizawa Takata Hasegawa Ishii Yuri Nishimura Iijima Nishiguchi : We sought to compare the impact upon grip strength (GS) between the Mac-2 binding protein glycosylation isomer (M2BPGi) and...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1354: Distal Femoral Shortening Osteotomy for Severe Knee Flexion Contracture and Crouch Gait in Cerebral Palsy Journal of Clinical Medicine doi: 10.3390/jcm8091354 Authors: Hoon Park Byoung Kyu Park Kun-Bo Park Sharkawy Wagih Abdel-Baki Isaac Rhee Chan Woo Kim Hyun Woo Kim Although there have been advancements of surgical techniques to correct gait abnormalities seen in patients with cerebral palsy, the crouch gait remains one of the most difficult...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1357: Low Serum Paraoxonase-1 Activity Associates with Incident Cardiovascular Disease Risk in Subjects with Concurrently High Levels of High-Density Lipoprotein Cholesterol and C-Reactive Protein Journal of Clinical Medicine doi: 10.3390/jcm8091357 Authors: James P. Corsetti Charles E. Sparks Richard W. James Stephan J. L. Bakker Robin P. F. Dullaart Paroxonase-1 (PON1) is a key enzyme that inhibits low-density lipoprotein oxidation and consequently atherogenesis....
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1362: Characteristics of Patients Showing Discrepancy Between Bruch’s Membrane Opening-Minimum Rim Width and Peripapillary Retinal Nerve Fiber Layer Thickness Journal of Clinical Medicine doi: 10.3390/jcm8091362 Authors: Cho Kee Background: To investigate clinical characteristics of patients showing discrepancy between Bruch’s membrane opening minimum rim width (BMO-MRW) and peripapillary retinal nerve fiber layer (RNFL) thickness. Correlation with the...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1351: State of Art of Idiosyncratic Drug-Induced Neutropenia or Agranulocytosis, with a Focus on Biotherapies Journal of Clinical Medicine doi: 10.3390/jcm8091351 Authors: Andrès Villalba Zulfiqar Serraj Mourot-Cottet Gottenberg Introduction: Idiosyncratic drug-induced neutropenia and agranulocytosis is seldom discussed in the literature, especially for new drugs such as biotherapies outside the context of oncology. In the present paper, we report...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1352: A Prognostic Model for the Outcome of Nobel Biocare Dental Implants with Peri-Implant Disease after One Year Journal of Clinical Medicine doi: 10.3390/jcm8091352 Authors: Nobre Salvado Nogueira Rocha Ilg Maló Background: This investigation, based on a 1-year retrospective cohort study, aimed to estimate and validate a prognostic model for ailing and failing implants due to peri-implant disease. Methods: A total of 240 patients (male: 97;...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1350: TSLP Exacerbates Septic Inflammation via Murine Double Minute 2 (MDM2) Signaling Pathway Journal of Clinical Medicine doi: 10.3390/jcm8091350 Authors: Han Moon Kim Jeong Thymic stromal lymphopoietin (TSLP) is crucial for Th2-mediated inflammation. Sepsis is a serious systemic inflammatory reaction with organ dysfunction by infection. However, the function of TSLP during sepsis is poorly understood. Thus, we investigated a role and regulatory mechanism...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1349: Long Non-Coding RNAs Modulate Sjögren’s Syndrome Associated Gene Expression and Are Involved in the Pathogenesis of the Disease Journal of Clinical Medicine doi: 10.3390/jcm8091349 Authors: Dolcino Tinazzi Vitali Papa Puccetti Lunardi Primary Sjögren’s syndrome (pSjS) is a chronic systemic autoimmune disorder, primarily affecting exocrine glands; its pathogenesis is still unclear. Long non-coding RNAs (lncRNAs) are thought...
Sun Sep 01, 2019 03:00
JCM, Vol. 8, Pages 1348: Moderate Cardiovascular Exercise Speeds Up Neural Markers of Stimulus Evaluation During Attentional Control Processes Journal of Clinical Medicine doi: 10.3390/jcm8091348 Authors: Winneke Hübner Godde Voelcker-Rehage Moderate intensity cardiovascular exercise appears to provide a low-cost “intervention” on neurocognitive processes such as attentional control, yet the effects vary depending, for example, on cognitive task, time...
Fri Aug 30, 2019 03:00
JCM, Vol. 8, Pages 1347: Interventional Radiology Suite: A Primer for Trainees Journal of Clinical Medicine doi: 10.3390/jcm8091347 Authors: Bedros Taslakian Ross Ingber Eric Aaltonen Jeremy Horn Ryan Hickey Familiarity with different instruments and understanding the basics of image guidance techniques are essential for interventional radiology trainees. However, there are no structured references in the literature, and trainees are left to “pick it up as they...
Fri Aug 30, 2019 03:00
JoF, Vol. 5, Pages 79: Central Nervous System Infections Due to Aspergillus and Other Hyaline Molds Journal of Fungi doi: 10.3390/jof5030079 Authors: Marisa H. Miceli Central nervous system infections due to Aspergillus spp and other hyaline molds such as Fusarium and Scedosporium spp are rare but fatal conditions. Invasion of the central nervous system (CNS) tends to occur as a result of hematogenous dissemination among immunocompromised patients, and by local extension or direct inoculation...
Fri Aug 30, 2019 03:00
JPM, Vol. 9, Pages 42: Evidence to Support Inclusion of Pharmacogenetic Biomarkers in Randomised Controlled Trials Journal of Personalized Medicine doi: 10.3390/jpm9030042 Authors: Danielle Johnson Dyfrig Hughes Sir Munir Pirmohamed Andrea Jorgensen Pharmacogenetics and biomarkers are becoming normalised as important technologies to improve drug efficacy rates, reduce the incidence of adverse drug reactions, and make informed choices for targeted therapies. However, their wider...
Sun Sep 01, 2019 03:00
Medical Sciences, Vol. 7, Pages 93: Diuretic Activity of a Novel Peripherally-Restricted Orally-Active Kappa Opioid Receptor Agonist Medical Sciences doi: 10.3390/medsci7090093 Authors: Tyler C. Beck Matthew A. Hapstack Gautam S. Ghatnekar Thomas A. Dix Kappa-opioid agonists (KOAs) enhance cardiac performance, as well as reduce infarct size and prevent deleterious cardiac remodeling following myocardial infarction. Additionally, KOAs promote diuresis; however, there has been...
Sat Aug 31, 2019 03:00
Medical Sciences, Vol. 7, Pages 92: Incidence and Prevalence of Polymyalgia Rheumatica (PMR): The Importance of the Epidemiological Context. The Italian Case Medical Sciences doi: 10.3390/medsci7090092 Authors: Ciro Manzo Objectives: to evaluate incidence and prevalence rates of polymyalgia rheumatica (PMR) in Italy, depending on the epidemiological methodology used from time to time. Materials and Methods: A comprehensive literature search in MEDLINE and EMBASE was carried out. The...
Fri Aug 30, 2019 03:00
Medicina, Vol. 55, Pages 555: Long-Term Relationship between Psychological Distress and Continuous Sedentary Behavior in Healthy Older Adults: A Three Panel Study Medicina doi: 10.3390/medicina55090555 Authors: Yutaka Owari Nobuyuki Miyatake Background and objectives: Psychological distress (PD) is associated with continuous sedentary behaviors (CSB; based on the ratio of 1.5 metabolic equivalents (METs) sessions or more continuing for over 30 min) in older adults, but the long-term...
Sat Aug 31, 2019 03:00
Medicina, Vol. 55, Pages 554: Efficacy of Low-Dose Paroxetine for the Treatment of Hot Flushes in Surgical and Physiological Postmenopausal Women: Systematic Review and Meta-Analysis of Randomized Trials Medicina doi: 10.3390/medicina55090554 Authors: Gaetano Riemma Antonio Schiattarella Marco La Verde Giuseppina Zarobbi Simone Garzon Gaspare Cucinella Gloria Calagna Domenico Labriola Pasquale De Franciscis Background and Objectives: Hot flushes and sleep disturbances...
Sat Aug 31, 2019 03:00
Medicina, Vol. 55, Pages 556: The Morphopathogenetic Aspects of Intraabdominal Adhesions in Children under One Year of Age Medicina doi: 10.3390/medicina55090556 Authors: Anna Junga Māra Pilmane Zane Ābola Olafs Volrāts Background and Objectives: The morphopathogenesis of adhesions is a complex process, characterized by the accumulation of an extracellular matrix, inflammation and hypoxia. The regulatory role between morphopathogenic factors in adhesions has not yet been defined....
Sat Aug 31, 2019 03:00
Medicina, Vol. 55, Pages 552: A Population-Based Analysis of Incidence, Mortality, and Survival in Testicular Cancer Patients in Lithuania Medicina doi: 10.3390/medicina55090552 Authors: Drevinskaite Patasius Kincius Jievaltas Smailyte Background and objectives: The aim of this study was to analyze trends in testicular cancer incidence, mortality, and survival in Lithuania during the period 1998–2013. Materials and Methods: The study was based on all cases...
Fri Aug 30, 2019 03:00
Medicina, Vol. 55, Pages 553: Influence of Burnout on Patient Safety: Systematic Review and Meta-Analysis Medicina doi: 10.3390/medicina55090553 Authors: Garcia Abreu Ramos Castro Smiderle Santos Bezerra Background and Objectives: Several factors can compromise patient safety, such as ineffective teamwork, failed organizational processes, and the physical and psychological overload of health professionals. Studies about associations between burn out and patient...
Fri Aug 30, 2019 03:00
Medicina, Vol. 55, Pages 551: What Is the Clinical Evidence Supporting Trauma Team Training (TTT): A Systematic Review and Meta-Analysis Medicina doi: 10.3390/medicina55090551 Authors: Noonan Olaussen Mathew Mitra Smit Fitzgerald Background and Objectives: Major trauma centres manage severely injured patients using multi-disciplinary teams but the evidence-base that targeted Trauma Team Training (TTT) improves patients’ outcomes is unclear. This systematic...
Fri Aug 30, 2019 03:00
Medicina, Vol. 55, Pages 550: Impact of Endometriomas and Deep Infiltrating Endometriosis on Pregnancy Outcomes and on First and Second Trimester Markers of Impaired Placentation Medicina doi: 10.3390/medicina55090550 Authors: Carolina Scala Umberto Leone Roberti Maggiore Fabio Barra Matteo Tantari Simone Ferrero Background and objective: Previous studies did not draw a definitive conclusion about the influence of the role of deep endometriosis (DE) and ovarian endometrioma...
Fri Aug 30, 2019 03:00
Medicina, Vol. 55, Pages 549: The Impact of Hormonal Replacement Treatment in Postmenopausal Women with Uterine Fibroids: A State-of-the-Art Review of the Literature Medicina doi: 10.3390/medicina55090549 Authors: Elisa Moro Eugenia Degli Esposti Giulia Borghese Federica Manzara Margherita Zanello Diego Raimondo Giulia Gava Alessandro Arena Paolo Casadio Maria Cristina Meriggiola Renato Seracchioli Background and Objectives: Hormonal replacement therapy...
Fri Aug 30, 2019 03:00
Membranes, Vol. 9, Pages 113: A Facile Synthesis of (PIM-Polyimide)-(6FDA-Durene-Polyimide) Copolymer as Novel Polymer Membranes for CO2 Separation Membranes doi: 10.3390/membranes9090113 Authors: Iqubal Hossain Abu Zafar Al Munsur Tae-Hyun Kim Random copolymers made of both (PIM-polyimide) and (6FDA-durene-PI) were prepared for the first time by a facile one-step polycondensation reaction. By combining the highly porous and contorted structure of PIM (polymers with intrinsic microporosity)...
Sat Aug 31, 2019 03:00
Membranes, Vol. 9, Pages 112: Electrochemical Synthesis of Ammonia: Recent Efforts and Future Outlook Membranes doi: 10.3390/membranes9090112 Authors: Garagounis Vourros Stoukides Dasopoulos Stoukides Ammonia is a key chemical produced in huge quantities worldwide. Its primary industrial production is via the Haber-Bosch method; a process requiring high temperatures and pressures, and consuming large amounts of energy. In the past two decades, several alternatives to...
Fri Aug 30, 2019 03:00
Membranes, Vol. 9, Pages 111: Biofouling of Polyamide Membranes: Fouling Mechanisms, Current Mitigation and Cleaning Strategies, and Future Prospects Membranes doi: 10.3390/membranes9090111 Authors: Jane Kucera Reverse osmosis and nanofiltration systems are continuously challenged with biofouling of polyamide membranes that are used almost exclusively for these desalination techniques. Traditionally, pretreatment and reactive membrane cleanings are employed as biofouling control methods....
Fri Aug 30, 2019 03:00
MPs, Vol. 2, Pages 76: Quantifying Fluorescently Labeled Ceramide Levels in Human Sarcoma Cell Lines in Response to a Sphingomyelin Synthase Inhibitor Methods and Protocols doi: 10.3390/mps2030076 Authors: Srinath Pashikanti Farjana Afrin Trevor C. Meldrum John L. Stegelmeier Adriene Pavek Yashar A. Habashi Kaniz Fatema Jared J. Barrott Sphingolipid metabolism is an important process in sustaining the growth needs of rapidly dividing cancer cells. Enzymes that synthesize...
Sat Aug 31, 2019 03:00
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