Pharmaceuticals, Vol. 12, Pages 136: Cellular Mechanisms for Antinociception Produced by Oxytocin and Orexins in the Rat Spinal Lamina II—Comparison with Those of Other Endogenous Pain Modulators Pharmaceuticals doi: 10.3390/ph12030136 Authors: Eiichi Kumamoto Much evidence indicates that hypothalamus-derived neuropeptides, oxytocin, orexins A and B, inhibit nociceptive transmission in the rat spinal dorsal horn. In order to unveil cellular mechanisms for this antinociception, the effects...
Mon Sep 16, 2019 03:00
Pharmaceuticals, Vol. 12, Pages 137: Metal-Based Complexes as Pharmaceuticals for Molecular Imaging of the Liver Pharmaceuticals doi: 10.3390/ph12030137 Authors: Julia Greiser Wolfgang Weigand Martin Freesmeyer This article reviews the use of metal complexes as contrast agents (CA) and radiopharmaceuticals for the anatomical and functional imaging of the liver. The main focus was on two established imaging modalities: magnetic resonance imaging (MRI) and nuclear medicine, the latter...
Mon Sep 16, 2019 03:00
Pharmaceuticals, Vol. 12, Pages 135: Predictive Power of In Silico Approach to Evaluate Chemicals against M. tuberculosis: A Systematic Review Pharmaceuticals doi: 10.3390/ph12030135 Authors: Giulia Oliveira Timo Rodrigo Souza Silva Valle dos Reis Adriana Françozo de Melo Thales Viana Labourdette Costa Pérola de Oliveira Magalhães Mauricio Homem-de-Mello Mycobacterium tuberculosis (Mtb) is an endemic bacterium worldwide that causes tuberculosis (TB) and involves long-term...
Mon Sep 16, 2019 03:00
Pharmaceutics, Vol. 11, Pages 479: Assessing Drug Interaction and Pharmacokinetics of Loxoprofen in Mice Treated with CYP3A Modulators Pharmaceutics doi: 10.3390/pharmaceutics11090479 Authors: Paudel Shrestha Cho Shrestha Kim Lee Kim Jeong Lee Lee Loxoprofen (LOX) is a non-selective cyclooxygenase inhibitor that is widely used for the treatment of pain and inflammation caused by chronic and transitory conditions. Its alcoholic metabolites are formed...
Mon Sep 16, 2019 03:00
Pharmacy, Vol. 7, Pages 133: Training Community Pharmacy Staff How to Help Manage Urgent Mental Health Crises Pharmacy doi: 10.3390/pharmacy7030133 Authors: Nathaniel Rickles Albert Wertheimer Yifan Huang Nearly 44 million Americans are affected by mental illness every year. Many individuals, however, are not diagnosed and/or do not receive treatment. The present manuscript reviews the incidence of mental illness, the continuum from mental wellness to mental illness, and the role...
Mon Sep 16, 2019 03:00
Plants, Vol. 8, Pages 351: H2O2 Induces Association of RCA with the Thylakoid Membrane to Enhance Resistance of Oryza meyeriana to Xanthomonas oryzae pv. oryzae Plants doi: 10.3390/plants8090351 Authors: Mei Yang Ye Liang Wang Zhou Yu Yan Chen Oryza meyeriana is a wild species of rice with high resistance to Xanthomonas oryzae pv. oryzae (Xoo), but the detailed resistance mechanism is unclear. Ribulose-1, 5-bisphosphate carboxylase/oxygenase (Rubisco)...
Mon Sep 16, 2019 03:00
Plasma, Vol. 2, Pages 369-379: Experimental Investigation on the Influence of Target Physical Properties on an Impinging Plasma Jet Plasma doi: 10.3390/plasma2030029 Authors: Emanuele Simoncelli Augusto Stancampiano Marco Boselli Matteo Gherardi Vittorio Colombo The present work aims to investigate the interaction between a plasma jet and targets with different physical properties. Electrical, morphological and fluid-dynamic characterizations were performed on a plasma jet...
Mon Sep 16, 2019 03:00
Psych, Vol. 1, Pages 482-490: Medial Cortical Structures Mediate Implicit Trustworthiness Judgments about Kin Faces, but Not Familiar Faces: A Brief Report Psych doi: 10.3390/psych1010037 Authors: Steven M. Platek Judson C. Hendry Human kin recognition activates substrates of the extended facial processing network, notably the right-hemisphere structures involved in self-face recognition and posterior medial cortical substrates. To understand the mechanisms underlying prosociality...
Mon Sep 16, 2019 03:00
Religions, Vol. 10, Pages 531: Gods, Gurus, Prophets and the Poor: Exploring Informal, Interfaith Exchanges among Working Class Female Workers in an Indian City Religions doi: 10.3390/rel10090531 Authors: Atreyee Sen This article revolves around the narratives of Sabita (Muslim), Radha (Hindu) and Sharleen (Christian), migrant women in their mid-forties, who have been working as maids, cooks and cleaners in middle-class housing colonies in Kolkata, a city in eastern India. Informal understandings...
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Religions, Vol. 10, Pages 530: Arguing over the Buddhist Pedigree of Tibetan Medicine: A Case Study of Empirical Observation and Traditional Learning in 16th- and 17th-Century Tibet Religions doi: 10.3390/rel10090530 Authors: James Duncan Gentry This article examines the relationship between the practice and theory of medicine and Buddhism in premodern Tibet. It considers a polemical text composed by the 16th–17th-century Tibetan physician and tantric Buddhist expert Sokdokpa...
Mon Sep 16, 2019 03:00
Risks, Vol. 7, Pages 97: DeepTriangle: A Deep Learning Approach to Loss Reserving Risks doi: 10.3390/risks7030097 Authors: Kevin Kuo We propose a novel approach for loss reserving based on deep neural networks. The approach allows for joint modeling of paid losses and claims outstanding, and incorporation of heterogeneous inputs. We validate the models on loss reserving data across lines of business, and show that they improve on the predictive accuracy of existing stochastic methods....
Mon Sep 16, 2019 03:00
Sci, Vol. 1, Pages 54: Are Scientific Models of Life Testable? A Lesson from Simpson’s Paradox Sci doi: 10.3390/sci1020054 Authors: Bandyopadhyay Grunska Dcruz Greenwood We address the need for a model by considering two competing theories regarding the origin of life: (i) the Metabolism First theory and (ii) the RNA World theory. We discuss two inter-related points. (I) Models are valuable tools in understanding both the processes and intricacies of the origin of life issues....
Mon Sep 16, 2019 03:00
Social Sciences, Vol. 8, Pages 263: Implementation of the ISO 26000 Guidelines on Active Participation and Community Development Social Sciences doi: 10.3390/socsci8090263 Authors: Oscar Daniel Licandro Adán Guillermo Ramírez García Lisandro José Alvarado-Peña Luis Alfredo Vega Osuna Patricia Correa The ISO 26000 Guidance provides valuable conceptual and methodological guidelines for making corporate social action an effective tool through which organizations contribute to...
Mon Sep 16, 2019 03:00
Sports, Vol. 7, Pages 213: Effects of Protective American Football Headgear on Peripheral Vision Reaction Time and Visual Target Detection in Division I NCAA Football Players Sports doi: 10.3390/sports7090213 Authors: Rachel A. Miller Rebecca R. Rogers Tyler D. Williams Mallory R. Marshall Justin R. Moody Robert W. Hensarling Christopher G. Ballmann The purpose of this study was to examine the effects of protective football headgear on peripheral vision reaction time...
Mon Sep 16, 2019 03:00
Toxins, Vol. 11, Pages 539: Identification of a Novel Saxitoxin Analogue, 12β-Deoxygonyautoxin 3, in the Cyanobacterium, Anabaena circinalis (TA04) Toxins doi: 10.3390/toxins11090539 Authors: Minowa Cho Oshima Konoki Yotsu-Yamashita Saxitoxin (STX) and its analogues, the potent voltage-gated sodium channel blockers, are biosynthesized by freshwater cyanobacteria and marine dinoflagellates. We previously identified several biosynthetic intermediates in the extract of...
Mon Sep 16, 2019 03:00
Vaccines, Vol. 7, Pages 116: Role of Antisperm Antibodies in Infertility, Pregnancy, and Potential forContraceptive and Antifertility Vaccine Designs: Research Progress and Pioneering Vision Vaccines doi: 10.3390/vaccines7030116 Authors: A. S. Dhama Chakraborty Samad Latheef Sharun Khurana K. Tiwari Bhatt K. Chaicumpa Sperm of humans, non-human primates, and other mammalian subjects is considered to be antigenic. The effect of changes in autoimmunity...
Mon Sep 16, 2019 03:00
Vaccines, Vol. 7, Pages 115: Immunological Analysis of a CCHFV mRNA Vaccine Candidate in Mouse Models Vaccines doi: 10.3390/vaccines7030115 Authors: Touraj Aligholipour Farzani Katalin Földes Koray Ergünay Hakan Gurdal Aliye Bastug Aykut Ozkul Development of new vaccine platforms against viral diseases is considered urgent. In recent years, mRNA constructs have attracted great interest in this field due to unique advantages over conventional gene transfer platforms. In...
Mon Sep 16, 2019 03:00
Viruses, Vol. 11, Pages 863: Clinical and Virological Aspects of HBV Reactivation: A Focus on Acute Liver Failure Viruses doi: 10.3390/v11090863 Authors: Olympia E. Anastasiou Martin Theissen Jens Verheyen Barbara Bleekmann Heiner Wedemeyer Marek Widera Sandra Ciesek Hepatitis B virus (HBV) reactivation in immunosuppressed patients can cause considerable morbidity and mortality. The aim of our study was to evaluate factors associated with acute liver failure (ALF) in...
Mon Sep 16, 2019 03:00
Viruses, Vol. 11, Pages 862: Diverse Morphology and Structural Features of Old and New World Hantaviruses Viruses doi: 10.3390/v11090862 Authors: Amar Parvate Evan P. Williams Mariah K. Taylor Yong-Kyu Chu Jason Lanman Erica Ollmann Saphire Colleen B. Jonsson To further understanding of the structure and morphology of the Orthohantavirus, family Hantaviridae, we have employed cryo-electron microscopy (cryo-EM) for three New World hantaviruses: Andes (ANDV), Sin Nombre...
Mon Sep 16, 2019 03:00
Viruses, Vol. 11, Pages 861: A Metabolomics Approach to Unravel Cricket Paralysis Virus Infection in Silkworm Bm5 Cells Viruses doi: 10.3390/v11090861 Authors: Luo-Luo Wang Luc Swevers Caroline Rombouts Ivan Meeus Lieven Van Meulebroek Lynn Vanhaecke Guy Smagghe How a host metabolism responds to infection with insect viruses and how it relates to pathogenesis, is little investigated. Our previous study observed that Cricket paralysis virus (CrPV, Dicistroviridae) causes...
Mon Sep 16, 2019 03:00
Vision, Vol. 3, Pages 47: An Adaptive Homeostatic Algorithm for the Unsupervised Learning of Visual Features Vision doi: 10.3390/vision3030047 Authors: Perrinet The formation of structure in the visual system, that is, of the connections between cellswithin neural populations, is by and large an unsupervised learning process. In the primary visualcortex of mammals, for example, one can observe during development the formation of cells selectiveto localized, oriented features, which...
Mon Sep 16, 2019 03:00
Water, Vol. 11, Pages 1933: Groundwater Autochthonous Microbial Communities as Tracers of Anthropogenic Pressure Impacts: Example from a Municipal Waste Treatment Plant (Latium, Italy) Water doi: 10.3390/w11091933 Authors: David Rossi Anna Barra Caracciolo Paola Grenni Flavia Cattena Martina Di Lenola Luisa Patrolecco Nicoletta Ademollo Ruggiero Ciannarella Giuseppe Mascolo Stefano Ghergo The groundwater behavior at a municipal solid waste disposal dump, located...
Mon Sep 16, 2019 03:00
Water, Vol. 11, Pages 1932: Improving Flows in Misaligned Culverts Water doi: 10.3390/w11091932 Authors: Rick Jaeger Carolyn Jacobs Katharina Tondera Neil Tindale This study investigated different approaches to optimize flows in misaligned culverts. Structures aligned with the natural stream are always preferred, as misalignments cause a change of direction at the culvert inlet associated with lower performance and sedimentation and erosion problems. This optimal positioning...
Mon Sep 16, 2019 03:00
Water, Vol. 11, Pages 1930: The Influence of Riparian Corridor Land Use on the Pesquería River’s Macroinvertebrate Community (N.E. Mexico) Water doi: 10.3390/w11091930 Authors: Daniel Castro-López Pablo Rodríguez-Lozano Rebeca Arias-Real Víctor Guerra-Cobián Narcís Prat The Earth’s freshwater ecosystems are currently under threat, particularly in developing countries. In Mexico, intensive land use and inadequate monitoring policies have resulted in the severe degradation...
Mon Sep 16, 2019 03:00
Water, Vol. 11, Pages 1931: The Effect of Chironomid Larvae on Nitrogen Cycling and Microbial Communities in Soft Sediments Water doi: 10.3390/w11091931 Authors: Aurelija Samuiloviene Marco Bartoli Stefano Bonaglia Ulisse Cardini Irma Vybernaite-Lubiene Ugo Marzocchi Jolita Petkuviene Tobia Politi Anastasija Zaiko Mindaugas Zilius The combination of biogeochemical methods and molecular techniques has the potential to uncover the black-box of the nitrogen (N)...
Mon Sep 16, 2019 03:00
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