Abstract Purpose Chronic granulomatous disease (CGD) is the most common phagocyte defect disease. Here, we describe 114 CGD patients in our center and report a rare female infant with XL-CGD to provide a better understanding of diagnosis, treatment, and prenatal diagnosis of CGD. Method Patients were diagnosed by DHR-1,2,3 flow cytometry assays and gene analysis....
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Special populations, which include the morbidly obese and patients with chronic, complex medical conditions that require long-term health care services and infrastructure, are at increased risk for morbidity and mortality when these services are disrupted ... (Source: SafetyLit)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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Death rates from heart disease, diabetes and stroke have been decreasing, but the rates are not decreasing as much as they once were — amplifying concerns that the obesity epidemic is undoing progress in the fight for heart health. (Source: Washington Post: To Your Health)
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Although the study was carried out in rats, the researchers at Binghamton University in New York say the likelihood of the same results occurring in obese humans is 'good'. (Source: the Mail online | Health)
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£18m funding for cancer support workers Related items fromOnMedica Better cancer treatment remains a ‘major’ public ‘priority’ Obesity as cause of cancer set to overtake smoking Is the NHS ready for ‘Cutting edge’ CAR T cell immunotherapy? Scotland launches its ‘Detect Cancer Early’ campaign Cancer patients using complementary meds die sooner (Source: OnMedica Latest News)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of...
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TUESDAY, Aug. 27, 2019 -- Rising obesity rates, coupled with an associated jump in diabetes and high blood pressure cases, appears to be undoing decades of gains made against heart disease, a new study finds. After 2010, the rate of deaths from... (Source: Drugs.com - Daily MedNews)
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Increasing childhood obesity rates are associated with not only adverse physical, but also mental health outcomes, including depression. These negative outcomes may be caused and/or exacerbated by the bullying and shaming overweight individuals experience.... (Source: SafetyLit)
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(Natural News) Green tea is a popular health drink in many parts of the world. In a recent study published in the Journal of Nutritional Biochemistry, researchers found that green tea helps regulate weight and prevent gut inflammation. “Two-thirds of American adults are overweight or obese, and we know that just telling people to eat less and... (Source: NaturalNews.com)
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We have a childhood obesity problem, but there are also problems with encouraging children to lose weight. (Source: NYT Health)
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From new employee entitlements to soap opera storylines, older women ’s health needs a bigger profileConnected as it is with ageing, it is not surprising that the menopause has a bad reputation. Even for women who have generally found their periods to be a nuisance, the cessation of the monthly cycle of egg production often comes as a shock. As well as the psychological impact of what used to euphemistically be called “the change”, the menopause brings with it symptoms for which a lot of women find...
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HOW TO sleep: Sleep is essential yet many people struggle to get the required amount. While there are many reasons for not getting enough sleep, mood is often one of the main contributors. Here are three telltale signs a person ’s mood is affecting their sleep. (Source: Daily Express - Health)MedWorm Message: Have you tried our new medical search engine? More powerful than before. Log on with your social media account. 100% free.
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As kids are spending more time using social media, new research suggests an adverse impact on mental health, especially in girls, mediated by poorer sleep, less exercise, and cyberbullying.Medscape Medical News (Source: Medscape Medical News Headlines)
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Experts share why bad dreams happen and how to stop them so you can get some damn sleep. (Source: Healthy Living - The Huffington Post)
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A study of British children by Loughborough University and University College London found that the blue light from their device screens is disrupting sleeping patterns. (Source: the Mail online | Health)
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Periodic limb movements in sleep with arousals are known to increase the risk for atrial fibrillation, but new research suggests they are also linked to increased risk for nonsustained ventricular tachycardia.Medscape Medical News (Source: Medscape Cardiology Headlines)
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BACKGROUND: Insufficient sleep, ... (Source: SafetyLit)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm running.
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Might giving high school students more sleep time by starting school later reduce their incidence of migraine?Headache (Source: Medscape Today Headlines)
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When most people think about sun-related damage, they probably worry about their skin. But the sun’s ultraviolet rays also pose a threat to a person’s eyes. According to a 2014 study funded by the U.S. National Eye Institute, part of the National Institutes of Health, UV radiation can damage proteins in the eye’s lens. Over time, this damage can raise a person’s risk for cataracts, which impair vision. “When you don’t wear protection, ultraviolet radiation you cannot see is penetrating the eye,...
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J reconstr MicrosurgDOI: 10.1055/s-0039-1695753 Background Regardless of the antecedent etiology, lower extremity salvage and reconstruction attempts to avoid amputation, restore limb function, and improve quality of life outcomes. This goal requires a treatment team well versed in neurovascular pathology, skeletal and soft tissue reconstruction, and physical rehabilitation. Methods A review was performed of historical milestones that lead to the development of orthoplastic...
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J reconstr MicrosurgDOI: 10.1055/s-0039-1695053 Background The use of the venous flap for simultaneous revascularization and coverage of soft tissue defects has been documented in the literature for over 30 years. First described in 1981, Nakayama et al demonstrated that a vein and overlying skin, or a venous flap, may be transposed from one area of the body to another with complete survival of the graft. The aim of this study was to conduct a systematic review of the literature to...
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Abstract Though researchers have documented that adolescents are vulnerable to coercion focused on reproductive and sexual autonomy, measures to assess this type of coercion for both adolescent females and males have not been validated in a population-based sample. The present study used secondary data collected from high school students across Kentucky (n = 16,137 from two independent samples in 2010 and 2014) to 1) determine if five items measuring adolescent reproductive and...
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Abstract Background Hypothyroidism is a common medical disorder which results in many metabolic effects, such as dyslipidemia, hypertension, accelerated atherosclerosis, and coronary artery disease. Hypothyroidism affects the renal physiology by affecting the renal blood flow, vascular resistance, and sodium handling. Recent studies have shown hypothyroidism is associated with decreased estimated renal function and proteinuria. Rhabdomyolysis...
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BOSTON, MA – Considered to be the Michael Jordan, Wayne Gretzky, and Serena Williams combined of this year’s graduating medical school class, outstanding fourth-year medical student Tanya Cash has currently amassed 4,986 letters of recommendation (LoRs) on ERAS. ERAS, which stands for Electronic Residency Application Service, is an online service fourth-year medical students use to apply to residency programs. “Only a maximum of 4 letters of recommendation can be assigned to any...
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Charleston, SC- In an effort to cut down on cost and auscultation, hospitals are deciding to change to a illustrated picture of a stethoscope. “This is much better,” Harris Sumfeld told reporters. Mr. Sumfeld, the hospital’s infection control officer, recently transferred last week from Staples Headquaters. Like most hospital administration, it only takes a week to understand the ins-and-outs of medicine. “I’ve been here a week and noticed that the current stethoscopes are major source...
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J Neurol Surg BDOI: 10.1055/s-0039-1694968 Objectives The incidence of seizures following a craniotomy for tumor removal varies between 15 and 20%. There has been increased use of endoscopic endonasal approaches (EEAs) for a variety of intracranial lesions due to its more direct approach to these pathologies. However, the incidence of postoperative seizures in this population is not well described. Methods This is a single-center, retrospective review of consecutive patients...
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Pre-entry tuberculosis screening, early primary care registration, and LTBI screening are strongly and independently associated with a lower tuberculosis incidence in new-entrant migrants.
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Global migration is increasing. Current estimates suggest that some 244 million people, representing 3·3% of the world's population, are living as international migrants.1 Migration has important implications for tuberculosis control because a high proportion of tuberculosis cases in low-incidence countries are in people who have migrated from countries where the disease is more frequent.2 Countries with a low incidence of tuberculosis have adopted policies for targeted testing of prospective migrants...
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Macrophages are important for effective iron recycling and erythropoiesis, but also play a crucial role in wound healing, orchestrating tissue repair. Recently, we demonstrated a significant accumulation of iron in healing wounds, and a requirement of iron for effective repair. Here, we sought to determine the influence of iron on macrophage function in the context of wound healing. Interestingly, wound macrophages extensively sequestered iron throughout healing, associated with a pro-healing M2...
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Solid organ transplantation is uncommon in ageing childhood cancer survivors. Organ-specific exposures were associated with increased solid organ transplantation incidence. Survival outcomes showed that solid organ transplantation should be considered for 5-year childhood cancer survivors with severe end-organ failure.
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Do anti-cancer and immunosuppressive agents cause cancer in man? What is the effect of these agents on existing cancers? These key fundamental questions were raised in 1972 by Penn and Starzl in their article entitled ‘The effect of immunosuppression on cancer’.1 Resulting speculations, which are highly relevant for the topic of solid organ transplantation in childhood cancer survivors, are considered by Andrew C Dietz and colleagues2 in The Lancet Oncology.
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Nature Medicine, Published online: 27 August 2019; doi:10.1038/s41591-019-0577-1Publisher Correction: Mapping exclusive breastfeeding in Africa between 2000 and 2017
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Try our specials of the day from NEJM Group: NEJM Catalyst: Health information initiatives will succeed only if they focus on patients' motivation to engage...
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All adults from ages 18 to 79 should be screened for hepatitis C virus (HCV) infection at least once, according to a draft recommendation from...
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High-dose vitamin D supplements don't appear to improve bone mineral density in healthy adults and may even have a negative impact, according to a...
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