Abstract To compare short and long-term graft uptake and hearing outcome of type I cartilage tympanoplasty between small, medium and large perforations using reinforced sliced conchal cartilage. A retrospective study conducted in a tertiary center. Fifty patients who under went type I tympanoplasty were enrolled. Their mean age was 29.30 years and follow-up time was 6 and 18 months. The preoperative, postoperative short-term and long-term hearing and graft uptake results were analyzed....
Publication date: Available online 12 August 2019Source: Operative Techniques in Otolaryngology-Head and Neck SurgeryAuthor(s): Jacob R. Brodsky, Guangwei ZhouVestibular disorders can be difficult to accurately diagnose and manage. A careful history and focused physical examination are typically adequate to establish a diagnosis and initiate medical treatment. Vestibular testing is an important component of the work-up, but it is particularly essential for patients being considered for surgical intervention...
Condition: Esophageal Squamous Cell CarcinomaIntervention: Drug: DurvalumabSponsor: Tiago BiachiNot yet recruiting
Publication date: Available online 13 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Abel Abera Negash, Daniel Asrat, Workeabeba Abebe, Tewodros Hailemariam, Meseret Gebre, Abraham Aseffa, Mario VaneechoutteAbstractIntroductionIn Ethiopia, there is a lack of data on pneumococcal serotypes causing acute otitis media (AOM) in children. We aimed to study the etiology, pneumococcal serotypes and antimicrobial resistance patterns of isolates from children with AOM...
Publication date: Available online 13 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Sydney Jiang, Catherina Yang, John Bent, Christina J. Yang, Mona Gangar, Michel Nassar, Barrie Suskin, Peer DarAbstractObjectiveCurrently no established criteria exist to guide use of ex utero intrapartum treatment (EXIT) for fetal neck mass management. This study aims to correlate prenatal radiographic findings with incidence of ex utero intrapartum treatment and necessity of...
Publication date: Available online 13 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Stephen O’Leary, Amelia Darke, Kathy Currie, Katie Davis, Hemi PatelAbstractAimTo report the surgical and audiological outcomes of myringoplasty (Type I tympanoplasty) in Indigenous Australian children living in remote and regional communities in northern Australia.MethodAn observational cohort study, with prospective recording of the details of surgery. Audiological outcomes...
Publication date: Available online 13 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Jonathan Hanna, Philip R. Brauer, Elliot Morse, Elisa Berson, Saral MehraAbstractObjectivesTo characterize cases of croup presenting to emergency departments (EDs) nationwide, analyze trends, and determine readmission rates.MethodsRetrospective review of the Nationwide Emergency Department Sample (2007-2014) and the National Hospital Ambulatory Medical Care Survey (2008- 2015).ResultsBoth...
Publication date: Available online 13 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Catherine F. Roy, Luhe Yang, Sam J. DanielAbstractMedulloblastoma is the most common pediatric malignant brain tumor and carries a relatively grim prognosis despite recent advances in multimodality therapy. Delays in diagnosis and treatment initiation may contribute to worst outcomes. Signs of increased intracranial pressure and ataxia are known presentations of posterior fossa...
Publication date: Available online 12 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): A.S. Quriba, E.M. Hassan
Publication date: Available online 12 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Pirabu Sakthivel, David Victor Kumar Irugu, Aanchal Kakkar, Kanwalpreet Kaur, Surabhi Jain, Raja Pramanik, Ahitagni BiswasAbstractSomatic-type malignancy arising in a teratoma of the sinonasal region is extremely unusual, creating a diagnostic dilemma. There are no definite guidelines for management of such cases.A 15-year-old male with a maxillary mass was misdiagnosed as angiomyolipoma,...
Publication date: Available online 12 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Mariann Gjervik Heldahl, Beth Eksveen, Marie BunneAbstractObjectivesA small proportion of children with Down Syndrome (DS) have severe to profound hearing loss and may potentially benefit from a cochlear implant (CI). Evidence on outcomes in DS is very limited, and there is a need for further investigation to provide a basis for clinical evaluation of candidates and outcomes....
Abstract Background This study assessed changes over time of survival of head and neck cutaneous squamous cell carcinoma (HNcSCC) with lymph node metastases. Methods A multicenter analysis of 1301 patients with metastatic HNcSCC treated between 1980 and 2017. Differences in disease‐specific survival (DSS) and overall survival (OS) by decade were assessed using multivariate Cox regression. Results Over the study period, we noted an increase in the proportion of patients aged over 80 years...
Abstract Background The aims of this study were to report our center's experience with infratemporal fossa (ITF) tumors, to review the treatment modalities and outcomes. Methods Data of patients that underwent resection of ITF tumors in a single tertiary referral medical center were collected and analyzed. Results Sixty‐three patients were included. Sarcoma was the most common pathology (18; 29%). The most common surgical approach was the preauricular‐orbitozygomatic approach (24;...
Abstract Background Common in head and neck cancer patients, trismus can make speech and swallowing difficult and can compromise quality of life (QOL). Jaw range of motion exercise therapy may prevent or treat trismus in surgical patients. While the importance of these exercises is well‐documented, there is little literature regarding the optimal timing of exercise initiation. Methods A prospective pilot study investigated the effects of early vs late jaw exercise intervention on postoperative...
Zusammenfassung Hintergrund Die chronische Rhinosinusitis (CRS) gehört zu den häufigsten chronischen Erkrankungen überhaupt. Die Prävalenz von Immundefekten ist bei diesen Patienten höher als in der Normalbevölkerung. Methodik Es wurden eine selektive Literaturrecherche in Pubmed und Medline für den Zeitraum 2008 bis 2018 durchgeführt und zusätzlich die aktuellen...
Zusammenfassung Die im Rahmen der transnasalen funktionellen Endoskopie erhobenen Befunde „Insuffizienz des oberen ösophagealen Sphinkters“, „Kardiainsuffizienz“, „Ösophagitis“, „gastrale Heterotopie“, „axiale Gleithernie“ und „sichtbare Aerosole“ werden in Beziehung zur pharyngealen Säureexposition durch Messung des pH-Werts im Oropharynx gesetzt. Signifikant erhöhte pharyngeale Säurebelastungen zeigten sich bei den Merkmalen gastrale Heterotopie und axiale Gleithernie. Für alle...
Zusammenfassung Als Folge der aktuellen demographischen Entwicklungen rücken vermehrt auch rechtliche Fragen im Zusammenhang mit der Behandlung älterer Menschen in den Fokus. Auch wenn Patienten im fortgeschrittenen Lebensalter natürlich erst einmal ganz normale Patienten sind, benötigen sie oftmals besondere ärztliche und pflegerische Begleitung. Dies schlägt sich nicht zuletzt auch in erhöhten Sorgfaltsanforderungen nieder, die ärztlicherseits zu beachten sind. Besondere rechtliche...
Abstract Background Physician practice patterns regarding diagnosis and management of malnutrition in the head and neck cancer patient population are not well studied. Methods A 17‐question survey was distributed to 1392 members of the American Head and Neck Society (AHNS). The impact of hospital type, fellowship training, experience, and specialty was assessed. Results Among AHNS members, there were 124 total respondents (9% response rate), including both otolaryngologists and radiation...
Objectives To evaluate the safety/efficacy of performing open bedside tracheotomy (OBT) in intensive care unit (ICU) patients and identify predictive factors for outcomes. Methods This is a retrospective cohort study. We identified 1000 consecutive patients undergoing OBT at a single university hospital starting from August 1, 2007. Complication rate, 30‐day mortality, decannulation rate, time to surgery (TTS) from initial consult, and ICU length of stay were analyzed. Multivariate analysis...
AbstractSensory systems such as the olfactory system detect chemical stimuli and thereby determine the relationships between the animal and its surroundings. Olfaction is one of the most conserved and ancient sensory systems in vertebrates. The vertebrate olfactory epithelium is colonized by complex microbial communities, but microbial contribution to host olfactory gene expression remains unknown. In this study, we show that colonization of germ-free zebrafish and mice with microbiota leads to widespread...
Condition: Ovarian CancerIntervention: Other: DNA and RNA extraction from FFPE or frozen tissue sampleSponsor: Institut BergoniéNot yet recruiting
Abstract Although anatomical development of the cochlear duct is thought to be complete by term birth, human newborns continue to show postnatal immaturities in functional measures such as otoacoustic emissions (OAEs). Some of these OAE immaturities are no doubt influenced by incomplete maturation of the external and middle ears in infants; however, the observed prolongation of distortion-product OAE phase-gradient delays in newborns cannot readily be explained by conductive factors....
Abstract Although anatomical development of the cochlear duct is thought to be complete by term birth, human newborns continue to show postnatal immaturities in functional measures such as otoacoustic emissions (OAEs). Some of these OAE immaturities are no doubt influenced by incomplete maturation of the external and middle ears in infants; however, the observed prolongation of distortion-product OAE phase-gradient delays in newborns cannot readily be explained by conductive factors....
Related ArticlesPretreatment low prognostic nutritional index and low albumin-globulin ratio are predictive for overall survival in nasopharyngeal cancer. Eur Arch Otorhinolaryngol. 2019 Aug 10;: Authors: Gundog M, Basaran H Abstract PURPOSE: We designed this retrospective study to identify predictive value of prognostic nutritional index (PNI) and albumin-globulin ratio (AGR) in nasopharyngeal cancer patients (NPC). METHODS: 95 non-metastatic...
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Abstract In 1997, deShazo et al.1, 2 conducted a literature review and proposed a novel classification of fungal rhinosinusitis. The authors divided fungal rhinosinusitis into invasive and noninvasive forms. The classification included acute and chronic invasive fungal rhinosinusitis (AIFRS and CIFRS), chronic granulomatous fungal rhinosinusitis, fungus ball, and allergic fungal rhinosinusitis (AFRS). Nowadays, the classification proposed by deShazo et al. is widely accepted and is frequently cited...
Publication date: Available online 10 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Kristen L. Yancey, Loyce J. Cheromei, Jackie Muhando, Jim Reppart, James L. Netterville, Asitha DL. JayawardenaABSTRACTObjectiveTo develop a sustainable, comprehensive, intervention-based approach to pediatric hearing care in low- and middle income countries (LMICs) where global hearing loss is most heavily concentrated.MethodsCommunity health workers (CHWs) in Kilifi county,...
Related ArticlesComparison of prognostic implications between the 7th and 8th edition of AJCC TNM staging system for head and neck soft-tissue sarcoma in adult patients. Eur Arch Otorhinolaryngol. 2019 Aug 09;: Authors: Kim H, Choi N, Baek CH, Son YI, Jeong HS, Chung MK Abstract PURPOSE: This study aimed to investigate the prognostic factors for head and neck soft-tissue sarcoma (HNSTS) in adults, with the comparisons between the 7th and 8th edition...
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Facial nerve baroparesis is a rare complication of middle ear barotrauma reported almost exclusively in overpressure events related to diving and flying. Until the development of Eustachian tube balloon dilation, no diving compatible options existed to effectively and safely prevent recurrence. We present a case of a U.S. Navy diver with a history of repeated ipsilateral facial nerve paresis that occurred during diving. The patient underwent Eustachian tube balloon dilation of the affected side....
Objectives/Hypothesis To report the efficacy and safety of transtympanic plugging of the eustachian tube (ET) using a silicone plug (Kobayashi plug) for chronic patulous ET (PET). Study Design Prospective and multicenter trial conducted in which 30 PET patients were resistant to at least 6 months of conservative treatment. Methods The efficacy and safety of 28 and 27 patients, respectively, were analyzed. All patients fulfilled inclusion and exclusion criteria. The primary end point...
Abstract The human stratum corneum (SC) contains an abundant amount of carotenoid antioxidants, quenching free radicals and thereby protecting the skin. For the precise measurements of the depth‐dependent carotenoid concentration, confocal Raman microscopy is a suitable method. The quantitative concentration can be determined by the carotenoid related peak intensity of a Gaussian function approached at ≈1524 cm−1 using non‐linear regression. Results show that the carotenoid concentration is higher...
Abstract Apolipoprotein B mRNA editing enzyme, catalytic polypeptide‐like (APOBEC) family consists of deaminases. Some isozymes of APOBEC3 are induced upon human papillomavirus infection or development of psoriasis skin lesions. However, the involvement of APOBEC3 in keratinocyte differentiation has not been addressed. We herein sought to evaluate the roles of APOBECs in mouse primary keratinocyte differentiation. We found that expression levels of APOBEC1 and APOBEC3 were increased during calcium‐induced...
Abstract Background Approximately 30% of nonsurgically treated patients with laryngeal squamous cell carcinoma will suffer recurrence, and many will be clinically N0; the indication for elective neck dissection (END) remains uncertain. We aimed to determine whether END is indicated during salvage laryngectomy. Methods Systematic review and meta‐analysis. Results A total of 1141 patients were identified from 17 studies. Occult nodal positivity was 13.7% (106/775) confidence interval...
AbstractRecent studies suggest that frugivorous primates might display a preference for the ethanol produced by microbia in overripe, fermenting fruit as an additional source of calories. We therefore assessed the taste responsiveness of eight spider monkeys (Ateles geoffroyi) to the range of ethanol concentrations found in overripe, fermenting fruit (0.05-3.0%) and determined taste preference thresholds as well as relative taste preferences for ethanol presented in sucrose solutions and in fruit...
Abstract Maxillofacial trauma, a common injury in urban population following road traffic accident or act of interpersonal violence of which orbital floor fractures is common. It impairs the integrity of the extraocular muscles and may be accompanied by enophthalmos, orbital deformity and diplopia. Orbital reconstruction is essential to improve anatomical and visual deformity. Repair of orbital floor is done by autologous bone graft or synthetic implants. Compare outcome of orbital...
Publication date: Available online 10 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Mohammad Soleimani, Sepehr Eslami, Reza Amani-Bei, Sadra Ansaripour
Publication date: Available online 10 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Aaqilah Bhamjee, Talita le Roux, Kurt Schlemmer, Jenny Perold, Nicolize Cass, Kelly Schroeder, Dani Schlesinger, Deon Ceronio, Bart VinckAbstractObjectiveTo determine and describe parent-perceived challenges related to the pediatric cochlear implantation process and support services received.MethodA multicenter survey study across six cochlear implant (CI) programs in South Africa...
Publication date: Available online 9 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Michael A. Belsky, Noel Jabbour
Publication date: Available online 9 August 2019Source: International Journal of Pediatric OtorhinolaryngologyAuthor(s): Malene Nøhr Demant, Ramon Gordon Jensen, Mahmood F. Bhutta, Gunnar Hellmund Laier, Jørgen Lous, Preben HomøeAbstractIntroductionGreenland has one of the highest prevalences of otitis media in the world. However, access to ear specialists throughout Greenland is limited and currently there are no national guidelines for treatment or prevention. Tele-otoscopy may be beneficial in...
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