Παρασκευή 3 Απριλίου 2020

An Uncomplicated Delivery in a Patient with Covid-19 in the United States
To rapidly communicate information on the global clinical effort against Covid-19, the Journal has initiated a series of case reports that offer important teaching points or novel findings. The case reports should be viewed as observations rather than as recommendations for evaluation or treatment.…
The New England Journal of Medicine: Search Results in Emergency Medicine
Wed Apr 01, 2020 03:00
Genetics and Gender in Acute Pain and Perioperative Opioid Analgesia
Publication date: Available online 1 April 2020Source: Anesthesiology ClinicsAuthor(s): Albert Hyukjae Kwon, Pamela Flood
ScienceDirect Publication: Anesthesiology Clinics
Thu Apr 02, 2020 13:53
Ethical Issues Confronting Muslim Patients in Perioperative and Critical Care Environments: A Survey of Islamic Jurisprudence
Publication date: Available online 1 April 2020Source: Anesthesiology ClinicsAuthor(s): Andrew C. Miller, Abba M. Khan, Karim Hebishi, Alberto A. Castro Bigalli, Amir Vahedian-Azimi
ScienceDirect Publication: Anesthesiology Clinics
Thu Apr 02, 2020 13:53
Gender, Racial, and Socioeconomic Issues in Perioperative Medicine
Publication date: Available online 1 April 2020Source: Anesthesiology ClinicsAuthor(s): Lee A. Fleisher
ScienceDirect Publication: Anesthesiology Clinics
Thu Apr 02, 2020 13:53
Gender Differences in Postoperative Outcomes After Cardiac Surgery
Publication date: Available online 1 April 2020Source: Anesthesiology ClinicsAuthor(s): Allison J. Bechtel, Julie L. Huffmyer
ScienceDirect Publication: Anesthesiology Clinics
Thu Apr 02, 2020 13:53
Two Sides of the Same Coin: Addressing Racial and Gender Disparities Among Physicians and the Impact on the Community They Serve
Publication date: Available online 1 April 2020Source: Anesthesiology ClinicsAuthor(s): Ebony J. Hilton, Nadia Lunardi, Roshni Sreedharan, Kristina L. Goff, Mariam Batakji, Dorothea S. Rosenberger
ScienceDirect Publication: Anesthesiology Clinics
Thu Apr 02, 2020 13:53
Gender, Racial, and Socioeconomic Issues in Perioperative Medicine
Publication date: Available online 1 April 2020Source: Anesthesiology ClinicsAuthor(s): Katherine T. Forkin, Lauren K. Dunn, Edward C. Nemergut
ScienceDirect Publication: Anesthesiology Clinics
Thu Apr 02, 2020 13:53
The Flaw of Medicine: Addressing Racial and Gender Disparities in Critical Care
Publication date: Available online 1 April 2020Source: Anesthesiology ClinicsAuthor(s): Ebony J. Hilton, Kristina L. Goff, Roshni Sreedharan, Nadia Lunardi, Mariam Batakji, Dorothea S. Rosenberger
ScienceDirect Publication: Anesthesiology Clinics
Thu Apr 02, 2020 13:53
Use of psycho-oncological services by prostate cancer patients: A multilevel analysis.
Related ArticlesUse of psycho-oncological services by prostate cancer patients: A multilevel analysis. Cancer Med. 2020 Mar 31;: Authors: Breidenbach C, Roth R, Ansmann L, Wesselmann S, Dieng S, Carl EG, Feick G, Oesterle A, Bach P, Beyer B, Borowitz R, Erdmann J, Kunath F, Oostdam SJ, Tsaur I, Zengerling F, Kowalski C Abstract BACKGROUND: Cancer patients often suffer from psychological distress. Psycho-oncological services (POS) have been established...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Reprograming the tumor immunologic microenvironment by neoadjuvant chemotherapy in osteosarcoma.
Related ArticlesReprograming the tumor immunologic microenvironment by neoadjuvant chemotherapy in osteosarcoma. Cancer Sci. 2020 Mar 30;: Authors: Deng C, Xu Y, Fu J, Zhu X, Chen H, Xu H, Wang G, Song Y, Song G, Lu J, Liu R, Tang Q, Huang W, Wang J Abstract Tumor-infiltrating immune cells play a crucial role in tumor progression and response to treatment. However, limited studies on infiltrating immune cells have shown inconsistent and even controversial...
pubmed: future oncology
Thu Apr 02, 2020 13:51
The CRISP(Y) Future of Pediatric Soft Tissue Sarcomas.
Related ArticlesThe CRISP(Y) Future of Pediatric Soft Tissue Sarcomas. Front Chem. 2020;8:178 Authors: Pomella S, Rota R Abstract The RNA-guided clustered regularly interspaced palindromic repeats (CRISPR)/associated nuclease 9 (Cas9)-based genome editing technology has increasingly become a recognized method for translational research. In oncology, the ease and versatility of CRISPR/Cas9 has made it possible to obtain many results in the identification...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Automated endoscopic detection and classification of colorectal polyps using convolutional neural networks.
Related ArticlesAutomated endoscopic detection and classification of colorectal polyps using convolutional neural networks. Therap Adv Gastroenterol. 2020;13:1756284820910659 Authors: Ozawa T, Ishihara S, Fujishiro M, Kumagai Y, Shichijo S, Tada T Abstract Background: Recently the American Society for Gastrointestinal Endoscopy addressed the 'resect and discard' strategy, determining that accurate in vivo differentiation of colorectal polyps (CP)...
pubmed: future oncology
Thu Apr 02, 2020 13:51
The Interplay Between Reproductive Tract Microbiota and Immunological System in Human Reproduction.
Related ArticlesThe Interplay Between Reproductive Tract Microbiota and Immunological System in Human Reproduction. Front Immunol. 2020;11:378 Authors: Al-Nasiry S, Ambrosino E, Schlaepfer M, Morré SA, Wieten L, Voncken JW, Spinelli M, Mueller M, Kramer BW Abstract In the last decade, the microbiota, i.e., combined populations of microorganisms living inside and on the surface of the human body, has increasingly attracted attention of researchers...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Dose assessment in dental cone-beam computed tomography: Comparison of optically stimulated luminescence dosimetry with Monte Carlo method.
Related ArticlesDose assessment in dental cone-beam computed tomography: Comparison of optically stimulated luminescence dosimetry with Monte Carlo method. PLoS One. 2020;15(3):e0219103 Authors: Lee C, Yoon J, Han SS, Na JY, Lee JH, Kim YH, Hwang JJ Abstract The variety of cone-beam computed tomography (CBCT) machines and their applications has rapidly increased in recent years, making the dose evaluation of individual devices an important issue....
pubmed: future oncology
Thu Apr 02, 2020 13:51
Hyperprogression Under Immune Checkpoint-Based Immunotherapy-Current Understanding, The Role of PD-1/PD-L1 Tumour-Intrinsic Signalling, Future Directions and a Potential Large Animal Model.
Related ArticlesHyperprogression Under Immune Checkpoint-Based Immunotherapy-Current Understanding, The Role of PD-1/PD-L1 Tumour-Intrinsic Signalling, Future Directions and a Potential Large Animal Model. Cancers (Basel). 2020 Mar 27;12(4): Authors: Kocikowski M, Dziubek K, Parys M Abstract Immune evasion is a major challenge for the development of successful cancer treatments. One of the known mechanisms is the expression of immune checkpoints...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Time-driven activity-based costing of a novel form of CT-guided high-dose-rate brachytherapy intraoperative radiation therapy compared with conventional breast intraoperative radiation therapy for early stage breast cancer.
Related ArticlesTime-driven activity-based costing of a novel form of CT-guided high-dose-rate brachytherapy intraoperative radiation therapy compared with conventional breast intraoperative radiation therapy for early stage breast cancer. Brachytherapy. 2020 Mar 28;: Authors: Suralik G, Rudra S, Dutta SW, Yu J, Sanders JC, Schad MD, Janowski EM, Su L, Libby B, Showalter SL, Lobo JM, Showalter TN Abstract INTRODUCTION: Intraoperative radiation therapy...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Using big data in pediatric oncology: Current applications and future directions.
Related ArticlesUsing big data in pediatric oncology: Current applications and future directions. Semin Oncol. 2020 Feb 29;: Authors: Major A, Cox SM, Volchenboum SL Abstract Pediatric cancer is a rare disease with a low annual incidence, which presents a significant challenge in being able to collect enough data to fuel clinical discoveries. Big data registry trials hold promise to advance the study of pediatric cancers by allowing for the combination...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Low expression of NCALD is associated with chemotherapy resistance and poor prognosis in epithelial ovarian cancer.
Related ArticlesLow expression of NCALD is associated with chemotherapy resistance and poor prognosis in epithelial ovarian cancer. J Ovarian Res. 2020 Mar 30;13(1):35 Authors: Feng LY, Li L Abstract BACKGROUND: Low expression of NCALD(neurocalcin delta) in peripheral blood of ovarian cancer patients predicts poor prognosis. However, the molecular mechanism of NCALD in ovarian cancer and its relationship with chemotherapy outcomes is unclear. The...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Impact of individual background on the unmet needs of cancer survivors and caregivers - a mixed-methods analysis.
Related ArticlesImpact of individual background on the unmet needs of cancer survivors and caregivers - a mixed-methods analysis. BMC Cancer. 2020 Mar 30;20(1):263 Authors: Watanabe K, Katayama K, Yoshioka T, Narimatsu H Abstract BACKGROUND: Cancer survivors and their caregivers may have various unmet needs that are medically difficult to solve. Previous studies have suggested the relations between individuals' backgrounds and their unmet needs....
pubmed: future oncology
Thu Apr 02, 2020 13:51
Functionally Significant Coumarin-Related Variant Alleles and Time to Therapeutic Range in Chilean Cardiovascular Patients.
Related ArticlesFunctionally Significant Coumarin-Related Variant Alleles and Time to Therapeutic Range in Chilean Cardiovascular Patients. Clin Appl Thromb Hemost. 2020 Jan-Dec;26:1076029620909154 Authors: Rojo M, Roco AM, Suarez M, Lavanderos MA, Verón G, Bertoglia MP, Arredondo A, Nieto E, Rubilar JC, Tamayo F, Cruz D, Muñoz J, Bravo G, Salas P, Mejías F, Véliz P, Godoy G, Varela NM, Llull G, Quiñones LA Abstract Despite the development of new...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Quality of life with second or third line nab-paclitaxel-based regimens in advanced non-small-cell lung cancer.
Related ArticlesQuality of life with second or third line nab-paclitaxel-based regimens in advanced non-small-cell lung cancer. Future Oncol. 2020 Mar 31;: Authors: Ponce Aix S, Talbot D, Govindan R, Dols MC, Postmus PE, Lewanski C, Bennouna J, Fischer JR, Juan-Vidal O, Stewart DJ, Ardizzoni A, Bhore R, Wolfsteiner M, Reck M, Ong TJ, Morgensztern D Abstract Aim: Evaluate quality of life (QoL) in patients with advanced non-small cell lung cancer treated...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Radiation awareness in an Italian multispecialist sample assessed with a web-based survey.
Related ArticlesRadiation awareness in an Italian multispecialist sample assessed with a web-based survey. Acta Cardiol. 2020 Mar 31;:1-5 Authors: Giaccardi M, Anselmino M, Del Greco M, Mascia G, Paoletti Perini A, Mascia P, De Ferrari GM, Picano E Abstract Introduction: The awareness of radiation doses and risks, also during interventional cardiology procedures, is essential today in order to apply the risk-benefit assessment and to reinforce the...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Adverse events in women switching from olaparib capsules to tablets: retrospective observational study of US claims data.
Related ArticlesAdverse events in women switching from olaparib capsules to tablets: retrospective observational study of US claims data. Future Oncol. 2020 Mar 31;: Authors: Banerjee S, Davidson R, McLaurin K, Sawyer W, Long GH Abstract Aim: Describe rates of prespecified adverse events in patients who switched from olaparib capsules to tablets. Patients & methods: Retrospective, observational cohort analysis using self-controlled, pre-post...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Association between genetically predicted polycystic ovary syndrome and ovarian cancer: a Mendelian randomization study.
Related ArticlesAssociation between genetically predicted polycystic ovary syndrome and ovarian cancer: a Mendelian randomization study. Int J Epidemiol. 2019 06 01;48(3):822-830 Authors: Harris HR, Cushing-Haugen KL, Webb PM, Nagle CM, Jordan SJ, Australian Ovarian Cancer Study Group, Risch HA, Rossing MA, Doherty JA, Goodman MT, Modugno F, Ness RB, Moysich KB, Kjær SK, Høgdall E, Jensen A, Schildkraut JM, Berchuck A, Cramer DW, Bandera EV, Rodriguez L, Wentzensen N,...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Next generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors.
Related ArticlesNext generation sequencing of PD-L1 for predicting response to immune checkpoint inhibitors. J Immunother Cancer. 2019 01 24;7(1):18 Authors: Conroy JM, Pabla S, Nesline MK, Glenn ST, Papanicolau-Sengos A, Burgher B, Andreas J, Giamo V, Wang Y, Lenzo FL, Bshara W, Khalil M, Dy GK, Madden KG, Shirai K, Dragnev K, Tafe LJ, Zhu J, Labriola M, Marin D, McCall SJ, Clarke J, George DJ, Zhang T, Zibelman M, Ghatalia P, Araujo-Fernandez I, de la Cruz-Merino...
pubmed: future oncology
Thu Apr 02, 2020 13:51
Evaluating the immunoproteasome as a potential therapeutic target in cisplatin-resistant small cell and non-small cell lung cancer.
Related ArticlesEvaluating the immunoproteasome as a potential therapeutic target in cisplatin-resistant small cell and non-small cell lung cancer. Cancer Chemother Pharmacol. 2020 Mar 30;: Authors: Shoji T, Kikuchi E, Kikuchi J, Takashima Y, Furuta M, Takahashi H, Tsuji K, Maeda M, Kinoshita I, Dosaka-Akita H, Sakakibara-Konishi J, Konno S Abstract PURPOSE: We evaluated the expression of proteasome subunits to assess whether the proteasome could...
pubmed: cell cycle arrest
Thu Apr 02, 2020 13:49
The dual role of BI 2536, a small-molecule inhibitor that targets PLK1, in induction of apoptosis and attenuation of autophagy in neuroblastoma cells.
Related ArticlesThe dual role of BI 2536, a small-molecule inhibitor that targets PLK1, in induction of apoptosis and attenuation of autophagy in neuroblastoma cells. J Cancer. 2020;11(11):3274-3287 Authors: Li Z, Yang C, Li X, Du X, Tao Y, Ren J, Fang F, Xie Y, Li M, Qian G, Xu L, Cao X, Wu Y, Lv H, Hu S, Lu J, Pan J Abstract Neuroblastoma (NB) is the most common extra-cranial solid tumor in childhood with the overall 5 years' survival less than...
pubmed: cell cycle arrest
Thu Apr 02, 2020 13:49
Overexpression of DUSP6 enhances chemotherapy-resistance of ovarian epithelial cancer by regulating the ERK signaling pathway.
Related ArticlesOverexpression of DUSP6 enhances chemotherapy-resistance of ovarian epithelial cancer by regulating the ERK signaling pathway. J Cancer. 2020;11(11):3151-3164 Authors: Gao Y, Li H, Han Q, Li Y, Wang T, Huang C, Mao Y, Wang X, Zhang Q, Tian J, Irwin DM, Tan H, Guo H Abstract Objective: DUSP6 is a negative regulator of the ERK signaling pathway and plays an important role in chemotherapy-resistance. Previously we showed that DUSP6 is...
pubmed: cell cycle arrest
Thu Apr 02, 2020 13:49
Riluzole Enhances the Response of Human Nasopharyngeal Carcinoma Cells to Ionizing Radiation via ATM/P53 Signalling Pathway.
Related ArticlesRiluzole Enhances the Response of Human Nasopharyngeal Carcinoma Cells to Ionizing Radiation via ATM/P53 Signalling Pathway. J Cancer. 2020;11(11):3089-3098 Authors: Sun L, Wu C, Ming J, Nie X, Guo E, Zhang W, Hu G Abstract Riluzole is approved by the FDA as an amyotrophic lateral sclerosis (ALS) drug. Previous studies showed that treatment with riluzole suppressed the proliferation of many cancer cells. However, little is known about...
pubmed: cell cycle arrest
Thu Apr 02, 2020 13:49
Antiproliferative Effects of Roylea cinerea (D. Don) Baillon Leaves in Immortalized L6 Rat Skeletal Muscle Cell Line: Role of Reactive Oxygen Species Mediated Pathway.
Related ArticlesAntiproliferative Effects of Roylea cinerea (D. Don) Baillon Leaves in Immortalized L6 Rat Skeletal Muscle Cell Line: Role of Reactive Oxygen Species Mediated Pathway. Front Pharmacol. 2020;11:322 Authors: Bhatia A, Singh Buttar H, Arora R, Singh B, Singh A, Kaur S, Arora S Abstract Roylea cinerea (D. Don) Baill. (Lamiaceae) is an indigenous plant of Western Himalayas, and has been used by the native population for the treatment of...
pubmed: cell cycle arrest
Thu Apr 02, 2020 13:49
ANGPTL4 Promotes the Proliferation of Papillary Thyroid Cancer via AKT Pathway.
Related ArticlesANGPTL4 Promotes the Proliferation of Papillary Thyroid Cancer via AKT Pathway. Onco Targets Ther. 2020;13:2299-2309 Authors: Yang L, Wang Y, Sun R, Zhang Y, Fu Y, Zheng Z, Ji Z, Zhao D Abstract Purpose: Although papillary thyroid carcinoma (PTC) is associated with a generally favorable prognosis, about 15% of patients present recurrence and distant metastasis in the next decade leading to death. Angiopoietin-like 4 (ANGPTL4) is secreted...
pubmed: cell cycle arrest
Thu Apr 02, 2020 13:49
miR-4651 inhibits cell proliferation of gingival mesenchymal stem cells by inhibiting HMGA2 under nifedipine treatment.
Related ArticlesmiR-4651 inhibits cell proliferation of gingival mesenchymal stem cells by inhibiting HMGA2 under nifedipine treatment. Int J Oral Sci. 2020 Mar 31;12(1):10 Authors: Han X, Yang R, Yang H, Cao Y, Han N, Zhang C, Shi R, Zhang Z, Fan Z Abstract Drug-induced gingival overgrowth (DIGO) is recognized as a side effect of nifedipine (NIF); however, the underlying molecular mechanisms remain unknown. In this study, we found that overexpressed...
pubmed: cell cycle arrest
Thu Apr 02, 2020 13:49
Implication of the p53-Related miR-34c, -125b, and -203 in the Osteoblastic Differentiation and the Malignant Transformation of Bone Sarcomas.
Related ArticlesImplication of the p53-Related miR-34c, -125b, and -203 in the Osteoblastic Differentiation and the Malignant Transformation of Bone Sarcomas. Cells. 2020 Mar 27;9(4): Authors: Jacques C, Tesfaye R, Lavaud M, Georges S, Baud'huin M, Lamoureux F, Ory B Abstract The formation of the skeleton occurs throughout the lives of vertebrates and is achieved through the balanced activities of two kinds of specialized bone cells: the bone-forming...
pubmed: cell cycle arrest
Thu Apr 02, 2020 13:49
Pulsed low dose-rate irradiation response in isogenic HNSCC cell lines with different radiosensitivity.
Related ArticlesPulsed low dose-rate irradiation response in isogenic HNSCC cell lines with different radiosensitivity. Radiol Oncol. 2020 Mar 27;: Authors: Todorovic V, Prevc A, Zakelj MN, Savarin M, Bucek S, Groselj B, Strojan P, Cemazar M, Sersa G Abstract Background Management of locoregionally recurrent head and neck squamous cell carcinomas (HNSCC) is challenging due to potential radioresistance. Pulsed low-dose rate (PLDR) irradiation exploits...
pubmed: cell cycle arrest
Thu Apr 02, 2020 13:49
Ribociclib mitigates cisplatin-associated kidney injury through retinoblastoma-1 dependent mechanisms.
Related ArticlesRibociclib mitigates cisplatin-associated kidney injury through retinoblastoma-1 dependent mechanisms. Biochem Pharmacol. 2020 Mar 27;:113939 Authors: Young Kim J, Jayne LA, Bai Y, Feng MJHH, Clark MA, Chung S, W Christman J, Cianciolo RE, Singh Pabla N Abstract Aberrant cell cycle activation is a hallmark of carcinogenesis. Recently three cell cycle targeting cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have been approved for...
pubmed: cell cycle arrest
Thu Apr 02, 2020 13:49
From development to aging: the path to cellular senescence.
Related ArticlesFrom development to aging: the path to cellular senescence. Antioxid Redox Signal. 2020 Mar 31;: Authors: Sacco A, Belloni L, Latella L Abstract SIGNIFICANCE: Senescence is a cellular state induced by internal or external stimuli, which result in cell cycle arrest, morphological changes, dysfunctions in mitochondria and lysosome functionality as well as senescence-associated secretory phenotype (SASP). Senescent cells accumulate in...
pubmed: cell cycle arrest
Thu Apr 02, 2020 13:49
Salvage Free Tissue Transfer for Clival Osteoradionecrosis after Repeat Proton Beam Therapy.
Related ArticlesSalvage Free Tissue Transfer for Clival Osteoradionecrosis after Repeat Proton Beam Therapy. World Neurosurg. 2020 Mar 27;: Authors: Vieira de Oliveira Silva S, Nabil A, Maza G, Shahein M, Vankoevering K, Patel KB, Prevedello D, Carrau R, Ozer E, Bertazo GS, Albonette Felicio T Abstract A 56 years old man presented with a history of chronic headaches and dysarthria with tongue deviation to the right. MRI showed a lesion at the craniocervical...
leak of cerebrospinal fluid
Thu Apr 02, 2020 13:48
Hypoxemic features of obstructive sleep apnea and the risk of mortality: a cluster analysis.
Related ArticlesHypoxemic features of obstructive sleep apnea and the risk of mortality: a cluster analysis. Sleep Breath. 2020 Mar 30;: Authors: Labarca G, Jorquera J, Dreyse J, Salas C, Letelier F Abstract INTRODUCTION: Patients with moderate to severe obstructive sleep apnea (OSA) have an increased risk of cardiovascular comorbidities and mortality. Although different subtypes of OSA have been described, data about oximetric parameters and their suitability...
pubmed: sleep apnea
Thu Apr 02, 2020 13:47
Frequency of moderate-to-severe obstructive sleep apnea syndrome among children with snoring and blood pressure in the hypertensive range.
Related ArticlesFrequency of moderate-to-severe obstructive sleep apnea syndrome among children with snoring and blood pressure in the hypertensive range. Pediatr Nephrol. 2020 Mar 30;: Authors: Malakasioti G, Alexopoulos EI, Batziou N, Velentza L, Mylona AM, Lachanas V, Skoulakis C, Gourgoulianis K, Kaditis AG Abstract BACKGROUND: It is recommended that children with hypertension and loud snoring should be referred for polysomnography. We aimed to compare...
pubmed: sleep apnea
Thu Apr 02, 2020 13:47

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