Παρασκευή 3 Απριλίου 2020


The Importance of Sleep Fragmentation on the Hemodynamic Dipping in Obstructive Sleep Apnea Patients.
Related ArticlesThe Importance of Sleep Fragmentation on the Hemodynamic Dipping in Obstructive Sleep Apnea Patients. Front Physiol. 2020;11:104 Authors: Staats R, Barros I, Fernandes D, Grencho D, Reis C, Matos F, Valença J, Marôco J, de Almeida AB, Bárbara C Abstract Introduction: Obstructive sleep apnea (OSA) has been associated with non-dipping blood pressure (BP). The precise mechanism is still under investigation, but repetitive oxygen desaturation...
pubmed: sleep apnea
Thu Apr 02, 2020 13:47
Commentary - "Maxillomandibular Advancement for Obstructive Sleep Apnea Is Associated with Very Long-Term Overall Sleep-Related Quality-of-Life Improvement".
Related ArticlesCommentary - "Maxillomandibular Advancement for Obstructive Sleep Apnea Is Associated with Very Long-Term Overall Sleep-Related Quality-of-Life Improvement". J Oral Maxillofac Surg. 2020 Apr;78(4):e1-e4 Authors: Dolan JM, Weyh AM, Gomez J, Salman SO PMID: 32229018 [PubMed - in process]
pubmed: sleep apnea
Thu Apr 02, 2020 13:47
Denoising improves visualization of evoked potentials with limited number of trials.
Related ArticlesDenoising improves visualization of evoked potentials with limited number of trials. J Clin Neurosci. 2020 Mar 27;: Authors: Ahmadi M Abstract Ensemble averaging is typically used to enhance the signal to noise ratio (SNR) of event related potentials (ERPs). This approach has the disadvantage of extending the recording time. We present an alternative approach to achieve SNRs similar to the ones obtained with ensemble averaging but with...
J Clin Neurosci
Thu Apr 02, 2020 13:45
Expression and prognostic value of mRNAs in lower grade glioma with MGMT promoter methylated.
Related ArticlesExpression and prognostic value of mRNAs in lower grade glioma with MGMT promoter methylated. J Clin Neurosci. 2020 Mar 27;: Authors: Wang W, Li J, Lin F, Guo J, Zhao J Abstract Due to the varied overall survival (OS), limited studies focus on the factors that affect the prognosis for lower grade glioma patients (LGGs) with MGMT promoter methylated. A total of 579 samples (TCGA LGGs 456; CGGA LGGs 123) were included to identify potential...
J Clin Neurosci
Thu Apr 02, 2020 13:45
Early Adverse Events predict Survival Outcomes in HER2-positive Advanced Breast Cancer Patients treated with Lapatinib plus Capecitabine.
Related ArticlesEarly Adverse Events predict Survival Outcomes in HER2-positive Advanced Breast Cancer Patients treated with Lapatinib plus Capecitabine. J Cancer. 2020;11(11):3327-3333 Authors: Ang FLI, Rowland A, Modi ND, McKinnon RA, Sorich MJ, Hopkins AM Abstract Background: This study aimed to investigate the impact of early adverse events (AE) following the initiation of lapatinib plus capecitabine on the progression-free survival (PFS) and overall...
pubmed: her2-positive breast...
Thu Apr 02, 2020 13:45
Breast Cancer Patient with Li-Fraumeni Syndrome: A Case Report Highlighting the Importance of Multidisciplinary Management.
Related ArticlesBreast Cancer Patient with Li-Fraumeni Syndrome: A Case Report Highlighting the Importance of Multidisciplinary Management. Case Rep Oncol. 2020 Jan-Apr;13(1):130-138 Authors: Cirauqui B, Morán T, Estival A, Quiroga V, Etxaniz O, Balana C, Navarro M, Villà S, Ballester R, Margelí M Abstract Germline mutations in TP53, a tumor suppressor gene, are involved in the development of Li-Fraumeni syndrome, a rare disorder that predisposes carriers...
pubmed: her2-positive breast...
Thu Apr 02, 2020 13:45
International Consensus Conference for Advanced Breast Cancer, Lisbon 2019: ABC5 Consensus - Assessment by a German Group of Experts.
Related ArticlesInternational Consensus Conference for Advanced Breast Cancer, Lisbon 2019: ABC5 Consensus - Assessment by a German Group of Experts. Breast Care (Basel). 2020 Feb;15(1):82-95 Authors: Thomssen C, Lüftner D, Untch M, Haidinger R, Würstlein R, Harbeck N, Augustin D, Briest S, Ettl J, Fasching PA, Förster F, Kurbacher CM, Lück HJ, Marschner N, Müller L, Müller V, Perlova-Griff L, Radke I, Ruckhäberle E, Scheffen I, Schumacher-Wulf E, Schwoerer M, Steinfeld-Birg...
pubmed: her2-positive breast...
Thu Apr 02, 2020 13:45
Using Phosphatidylinositol Phosphorylation as Markers for Hyperglycemic Related Breast Cancer.
Related ArticlesUsing Phosphatidylinositol Phosphorylation as Markers for Hyperglycemic Related Breast Cancer. Int J Mol Sci. 2020 Mar 27;21(7): Authors: Devanathan N, Jones S, Kaur G, Kimble-Hill AC Abstract Studies have suggested that type 2 diabetes (T2D) is associated with a higher incidence of breast cancer and related mortality rates. T2D postmenopausal women have an ~20% increased chance of developing breast cancer, and women with T2D and breast...
pubmed: her2-positive breast...
Thu Apr 02, 2020 13:45
Prognostic and Predictive Impact of Beta-2 Adrenergic Receptor Expression in HER2-Positive Breast Cancer.
Related ArticlesPrognostic and Predictive Impact of Beta-2 Adrenergic Receptor Expression in HER2-Positive Breast Cancer. Clin Breast Cancer. 2020 Mar 04;: Authors: Caparica R, Richard F, Brandão M, Awada A, Sotiriou C, de Azambuja E Abstract BACKGROUND: Beta-2 adrenergic receptor (ADRB2) mediates proliferation and treatment resistance in preclinical models of human epidermal growth factor receptor 2 positive (HER2+) breast cancer. We evaluated ADRB2...
pubmed: her2-positive breast...
Thu Apr 02, 2020 13:45
Multifunctional hybrid nanoparticles as magnetic delivery systems for siRNA targeting the HER2 gene in breast cancer cells.
Related ArticlesMultifunctional hybrid nanoparticles as magnetic delivery systems for siRNA targeting the HER2 gene in breast cancer cells. Mater Sci Eng C Mater Biol Appl. 2020 Apr;109:110555 Authors: Cristofolini T, Dalmina M, Sierra JA, Silva AH, Pasa AA, Pittella F, Creczynski-Pasa TB Abstract Breast cancer is a major cause of death among women worldwide. Resistance to conventional therapies has been observed in HER2-positive breast cancer patients,...
pubmed: her2-positive breast...
Thu Apr 02, 2020 13:45
Prompt rewetting of drained peatlands reduces climate warming despite methane emissions
Nature Communications, Published online: 02 April 2020; doi:10.1038/s41467-020-15499-zDrained peatlands are sources of CO2, and though rewetting could curb emissions, this strategy results in elevated methane release. Here, the authors model peatland emissions scenarios and show that rewetting is a critical way to mitigate climate change despite potential methane increases.
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
A solution-processable and ultra-permeable conjugated microporous thermoset for selective hydrogen separation
Nature Communications, Published online: 02 April 2020; doi:10.1038/s41467-020-15503-6Rigidity, as seen in crosslinked polymers, and plastic processability are mutually exclusive properties. Here, the authors prepare a solution-processable conjugated microporous thermoset with permanent pores and demonstrate its application as a two-dimensional molecular sieving membrane for hydrogen separation.
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
Transient microglial absence assists postmigratory cortical neurons in proper differentiation
Nature Communications, Published online: 02 April 2020; doi:10.1038/s41467-020-15409-3Microglia temporarily disappear from the cortical plate in the midembryonic stage. This study demonstrated that microglial transient absence from the cortical plate is required for postmigratory neurons to appropriately fine-tune the expression of molecules needed for their proper differentiation.
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
TNIK signaling imprints CD8<sup>+</sup> T cell memory formation early after priming
Nature Communications, Published online: 02 April 2020; doi:10.1038/s41467-020-15413-7Coordinate expression of multiple factors play critical roles in the regulation between effector and memory CD8+ T cell differentiation. Here the authors show upon acute viral infection TNIK is critically required as a regulator of effector and memory T cell differentiation.
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
Spider-silk inspired polymeric networks by harnessing the mechanical potential of β-sheets through network guided assembly
Nature Communications, Published online: 02 April 2020; doi:10.1038/s41467-020-15312-xIt is known the β-sheet structures in silk-inspired materials generate increased mechanical properties. Here, the authors report on a method of creating silk-inspired materials using in situ formation of β-sheets in an amorphous polymer to replicate the structure of silk and increase the mechanical properties.
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
GPR56/ADGRG1 is associated with response to antidepressant treatment
Nature Communications, Published online: 02 April 2020; doi:10.1038/s41467-020-15423-5It is not fully understood why some patients respond or do not respond to antidepressant treatment. Here the authors show that in the blood of individuals with depression, GPR56 expression increases in responders to antidepressant treatment, but not in non-responders.
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
Phasor field diffraction based reconstruction for fast non-line-of-sight imaging systems
Nature Communications, Published online: 02 April 2020; doi:10.1038/s41467-020-15157-4Current implementations of non-line-of-sight imaging use reconstruction algorithms that are difficult to implement fast enough for real-time application using light efficient equipment. The authors present an algorithm for non-line-of-sight imaging that is low complexity and allows fast and efficient reconstruction on a standard computer.
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
Lamella-nanostructured eutectic zinc–aluminum alloys as reversible and dendrite-free anodes for aqueous rechargeable batteries
Nature Communications, Published online: 02 April 2020; doi:10.1038/s41467-020-15478-4Aqueous rechargeable Zn-ion batteries are attractive energy storage devices, but their wide adoption is impeded by the irreversible metallic Zn anode. Here the authors report lamellar-nanostructured eutectic Zn/Al alloys as reversible and dendrite-free anodes for improved battery performance.
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
Prompt rewetting of drained peatlands reduces climate warming despite methane emissions
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
A solution-processable and ultra-permeable conjugated microporous thermoset for selective hydrogen separation
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
Transient microglial absence assists postmigratory cortical neurons in proper differentiation
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
TNIK signaling imprints CD8<sup>+</sup> T cell memory formation early after priming
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
Spider-silk inspired polymeric networks by harnessing the mechanical potential of β-sheets through network guided assembly
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
GPR56/ADGRG1 is associated with response to antidepressant treatment
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
Phasor field diffraction based reconstruction for fast non-line-of-sight imaging systems
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
Lamella-nanostructured eutectic zinc–aluminum alloys as reversible and dendrite-free anodes for aqueous rechargeable batteries
Nature Communications - current - nature.com science feeds
Thu Apr 02, 2020 03:00
Expert Consensus on Procedures and Operations of Navigation-guided Needle Biopsy Techniques for Skull Base Tumours.
Related ArticlesExpert Consensus on Procedures and Operations of Navigation-guided Needle Biopsy Techniques for Skull Base Tumours. Chin J Dent Res. 2020;23(1):27-32 Authors: Wang J, Guo CB, Zhu JH, Guo YX, Yu GY, He Y, Zhang WB, Zhang Y, Peng X, Liu XJ, Liu YP, Gu XM, Tian WD, Lu L, Li ZB, Zhang SL, Shen GF, Bao S, Li TJ, Fu KY, Society Of Oral And Maxillofacial Surgery, Chinese Stomatological Association Abstract Skull base surgery is an interdisciplinary...
Skull Base
Thu Apr 02, 2020 13:41
Clinical features of newly developed NF2 intracranial meningiomas through comparative analysis of pediatric and adult patients.
Related ArticlesClinical features of newly developed NF2 intracranial meningiomas through comparative analysis of pediatric and adult patients. Clin Neurol Neurosurg. 2020 Mar 19;194:105799 Authors: Li P, Wu T, Wang Y, Zhao F, Wang Z, Wang X, Wang B, Yang Z, Liu P Abstract OBJECTIVE: NF2 patients can develop new meningiomas throughout their lifetime. Little is known about the clinical features of newly developed NF2 meningiomas. In this study, we analyzed...
Skull Base
Thu Apr 02, 2020 13:41
Salvage Free Tissue Transfer for Clival Osteoradionecrosis after Repeat Proton Beam Therapy.
Related ArticlesSalvage Free Tissue Transfer for Clival Osteoradionecrosis after Repeat Proton Beam Therapy. World Neurosurg. 2020 Mar 27;: Authors: Vieira de Oliveira Silva S, Nabil A, Maza G, Shahein M, Vankoevering K, Patel KB, Prevedello D, Carrau R, Ozer E, Bertazo GS, Albonette Felicio T Abstract A 56 years old man presented with a history of chronic headaches and dysarthria with tongue deviation to the right. MRI showed a lesion at the craniocervical...
Skull Base
Thu Apr 02, 2020 13:41
Facial Schwannoma Management Outcomes: A Systematic Review of the Literature.
Related ArticlesFacial Schwannoma Management Outcomes: A Systematic Review of the Literature. Otolaryngol Head Neck Surg. 2020 Mar 31;:194599820913639 Authors: Bartindale M, Heiferman J, Joyce C, Anderson D, Leonetti J Abstract OBJECTIVE: To evaluate facial nerve outcomes of various management strategies for facial schwannomas by assimilating individualized patient data from the literature to address controversies in management. DATA SOURCES:...
Skull Base
Thu Apr 02, 2020 13:41
Authors' Response.
Related ArticlesAuthors' Response. J Forensic Sci. 2020 01;65(1):344 Authors: Crudele GDL, Merelli VG, Vener C, Cattaneo C PMID: 31792969 [PubMed - indexed for MEDLINE]
Skull Base
Thu Apr 02, 2020 13:41
Commentary on: Crudele GDL, Merelli VG, Vener C, Milani S, Cattaneo C. The frequency of cranial base fractures in lethal head trauma. J Forensic Sci doi: 10.1111/1556-4029.14149. Epub 2019 Aug 21.
Related ArticlesCommentary on: Crudele GDL, Merelli VG, Vener C, Milani S, Cattaneo C. The frequency of cranial base fractures in lethal head trauma. J Forensic Sci doi: 10.1111/1556-4029.14149. Epub 2019 Aug 21. J Forensic Sci. 2020 01;65(1):343 Authors: Hu J, Zheng N, Liang M PMID: 31792966 [PubMed - indexed for MEDLINE]
Skull Base
Thu Apr 02, 2020 13:41
Clinical features of nine cases of leucine-rich glioma inactivated 1 protein antibody-associated encephalitis.
Related ArticlesClinical features of nine cases of leucine-rich glioma inactivated 1 protein antibody-associated encephalitis. Acta Neurol Belg. 2020 Mar 31;: Authors: Li Y, Song F, Liu W, Wang Y Abstract To investigate clinical features of leucine-rich glioma inactivated 1 protein (LGI1) antibody-associated autoimmune encephalitis (AE). The clinical data were collected and analyzed in nine patients with LGI1 AE. All nine patients (100%) presented acute/subacute...
pubmed: epilepsy treatment
Thu Apr 02, 2020 13:36
Consumer Reports of "Keto Flu" Associated With the Ketogenic Diet.
Related ArticlesConsumer Reports of "Keto Flu" Associated With the Ketogenic Diet. Front Nutr. 2020;7:20 Authors: Bostock ECS, Kirkby KC, Taylor BV, Hawrelak JA Abstract Background: The ketogenic diet (KD) is a high-fat, low-carbohydrate diet that limits glucose and results in the production of ketones by the liver and their uptake as an alternative energy source by the brain. KD is an evidence-based treatment for intractable epilepsy. KD is also self-administered,...
pubmed: epilepsy treatment
Thu Apr 02, 2020 13:36
Predicting the Type of Tumor-Related Epilepsy in Patients With Low-Grade Gliomas: A Radiomics Study.
Related ArticlesPredicting the Type of Tumor-Related Epilepsy in Patients With Low-Grade Gliomas: A Radiomics Study. Front Oncol. 2020;10:235 Authors: Wang Y, Wei W, Liu Z, Liang Y, Liu X, Li Y, Tang Z, Jiang T, Tian J Abstract Purpose: The majority of patients with low-grade gliomas (LGGs) experience tumor-related epilepsy during the disease course. Our study aimed to build a radiomic prediction model for LGG-related epilepsy type based on magnetic...
pubmed: epilepsy treatment
Thu Apr 02, 2020 13:36
The Apelin/APJ System in Psychosis and Neuropathy.
Related ArticlesThe Apelin/APJ System in Psychosis and Neuropathy. Front Pharmacol. 2020;11:320 Authors: Lv SY, Chen WD, Wang YD Abstract Apelin, an endogenous neuropeptide, has been identified as the cognate ligand for the G-protein-coupled receptor APJ. Apelin, APJ messenger RNA, and protein are widely expressed in the central nervous system and peripheral tissues of humans and animals. The apelin/APJ system has been implicated in diverse physiological...
pubmed: epilepsy treatment
Thu Apr 02, 2020 13:36
Anti-Epileptogenic Effects of Antiepileptic Drugs.
Related ArticlesAnti-Epileptogenic Effects of Antiepileptic Drugs. Int J Mol Sci. 2020 Mar 28;21(7): Authors: Miziak B, Konarzewska A, Ułamek-Kozioł M, Dudra-Jastrzębska M, Pluta R, Czuczwar SJ Abstract Generally, the prevalence of epilepsy does not exceed 0.9% of the population and approximately 70% of epilepsy patients may be adequately controlled with antiepileptic drugs (AEDs). Moreover, status epilepticus (SE) or even a single seizure may produce...
pubmed: epilepsy treatment
Thu Apr 02, 2020 13:36
Retraction: Decreased bone mass and increased bone turnover with valproate therapy in adults with epilepsy.
Related ArticlesRetraction: Decreased bone mass and increased bone turnover with valproate therapy in adults with epilepsy. Neurology. 2020 Mar 30;: Authors: PMID: 32229624 [PubMed - as supplied by publisher]
pubmed: epilepsy treatment
Thu Apr 02, 2020 13:36
Dexmedetomidine in Enhanced Recovery After Surgery (ERAS) Protocols for Postoperative Pain
Abstract Purpose of Review Effective acute pain management has evolved considerably in recent years and is a primary area of focus in attempts to defend against the opioid epidemic. Persistent postsurgical pain (PPP) has an incidence of up to 30–50% and has negative outcome of quality of life and negative burden on individuals, family, and society. The 2016 American Society of Anesthesiologists (ASA) guidelines states that enhanced...
Headache Reports
Thu Apr 02, 2020 03:00

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