Best practice in reducing the suicide risk in head and neck cancer patients: a structured review. Br J Oral Maxillofac Surg. 2020 Jul 15;: Authors: Twigg JA, Anderson JM, Humphris G, Nixon I, Rogers SN, Kanatas A Abstract The treatment of head and neck cancer (HNC) is often radical and the patient's journey challenging, especially for individuals who are struggling with pre-existing mental health problems and who lack social support. Patients...
Mon Jul 20, 2020 14:11
Postoperative recovery of accelerometer-based physical activity in older cancer patients. Eur J Surg Oncol. 2020 Jun 24;: Authors: Jonker LT, Hendriks S, Lahr MM, van Munster BC, de Bock GH, van Leeuwen BL Abstract INTRODUCTION: Recovery of physical activity is an important functional outcome measure after cancer surgery. However, objective data on physical activity for older cancer patients is scarce. The aims of this study were to quantify...
Mon Jul 20, 2020 14:11
Patients' confidence in treatment decisions for early stage non-small cell lung cancer (NSCLC). Health Qual Life Outcomes. 2020 Jul 18;18(1):237 Authors: Pompili C, Holch P, Rogers Z, Absolom K, Clayton B, Franks K, Bekker H, Velikova G Abstract BACKGROUND: In early-stage Non-Small Cell Lung Cancer (NSCLC) patients, little is known about how to measure patient participation in Shared-Decision Making (SDM). We examined the psychometric properties...
Mon Jul 20, 2020 14:11
Transient Hepatotoxicity Induced by Vinblastine in a Young Girl with Chiasmatic low Grade Glioma. Curr Drug Saf. 2020 Jul 18;: Authors: Franke NE, Blok GJ, Voll ML, Schouten-van Meeteren AY Abstract BACKGROUND: Vinblastine (VBL) is a cytostatic drug frequently applied in children with lymphoma and progressive low-grade glioma (LGG) in children, with hematotoxicity as main side effect. CASE REPORT: Here we present a 7-month-old girl...
Mon Jul 20, 2020 14:11
The Influence of Different Disease States on Rituximab Pharmacokinetics. Curr Drug Metab. 2020 Jul 18;: Authors: Wang X, Du W, Zhang X, Li P Abstract BACKGROUND: The anti-CD20 antibody rituximab, which promotes the selective depletion of CD20 positive B cells, was the first targeted therapy that was approved for the treatment of B-cell malignancies, and it is now widely prescribed in both malignant and non-malignant, immune-related diseases....
Mon Jul 20, 2020 14:11
Publication date: Available online 19 July 2020Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): I. Sani, H. Bux, Y. Hamza
Mon Jul 20, 2020 14:10
Predominance of an altered sense of smell or taste among long-lasting symptoms in patients with mildly symptomatic COVID-19. Rhinology. 2020 Jul 19;: Authors: Boscolo-Rizzo P, Polesel J, Spinato G, Fabbris C, Menegaldo A, Borsetto D, Hopkins C PMID: 32683438 [PubMed - as supplied by publisher]
Mon Jul 20, 2020 14:01
Publication date: Available online 19 July 2020Source: Pathology - Research and PracticeAuthor(s): Zhihua Zuo, Yao Jiang, Shanshui Zeng, Yiqin Li, Jia Fan, Yongcan Guo, Hualin Tao
Mon Jul 20, 2020 13:58
Publication date: Available online 19 July 2020Source: American Journal of Infection ControlAuthor(s): Silpa N. Tadavarthy, KerriAnn Finnegan, Gretchen Bernatowicz, Elisha Lowe, Susan E Coffin, MaryLou Manning
Mon Jul 20, 2020 13:58
Nature Communications, Published online: 20 July 2020; doi:10.1038/s41467-020-17357-4OTX2 promotes tumour growth in Group 3 medulloblastoma. Here, the authors show that OTX2 regulates PAX3 to induce neural de-differentiation and promote tumourigenesis in Group 3 medulloblastoma.
Mon Jul 20, 2020 03:00
Nature Communications, Published online: 20 July 2020; doi:10.1038/s41467-020-17380-5The immune system can eradicate tumours, and several chemotherapy strategies have been reported to augment the immune system. Here, the authors report an exogenous magnetic field triggered strategy to boost Ferroptosis-like death and endow responsive MRI by using a biosafe hybrid core-shell vesicle for cancer therapy.
Mon Jul 20, 2020 03:00
Nature Communications, Published online: 20 July 2020; doi:10.1038/s41467-020-17399-8The molecular mechanisms regulating macrophage recruitment to tumors are unclear. Here, the authors use a Drosophila overgrowth model to show how damaged basement membranes recruit macrophages to undead tissue, via an interdependent effect of reactive oxygen species and matrix metalloproteinase 2.
Mon Jul 20, 2020 03:00
Nature Communications, Published online: 20 July 2020; doi:10.1038/s41467-020-17467-zTherapy-induced senescence reflects a biological effector principle that is underrecognized in lesion-focused cancer precision medicine. Here the authors utilize mouse lymphoma genetics to functionally dissect senescence and cross-species apply a novel senescence-based prognosticator to lymphoma patients.
Mon Jul 20, 2020 03:00
Nature Communications, Published online: 20 July 2020; doi:10.1038/s41467-020-17434-8Anion vacancies are a hurdle for technologies based on chalcogenide semiconductors and topological insulators. Even at room temperature, oxidation and cyanide etching can lead to selenium vacancies in CuInSe2 photovoltaic material but suitable post deposition treatments can mitigate their effect.
Mon Jul 20, 2020 03:00
Nature Communications, Published online: 20 July 2020; doi:10.1038/s41467-020-17456-2Malaria prevalence in Papua New Guinea has risen in recent years after almost a decade of decline. In this study, the authors demonstrate that long-lasting insecticidal nets used in the country that were manufactured since 2013 have significantly reduced bioefficacy.
Mon Jul 20, 2020 03:00
Nature Communications, Published online: 20 July 2020; doi:10.1038/s41467-020-17378-zFamilial carpal tunnel syndrome (CTS) is common, but causal genes are not characterized. Here the authors report two CTS-related mutations in two large families that impair secretion of COMP in tenocytes, leading to ER stress-induced unfolded protein response, inflammation and fibrosis in patients and mouse models.
Mon Jul 20, 2020 03:00
Nature Communications, Published online: 20 July 2020; doi:10.1038/s41467-020-17451-7Membrane contact sites between organelles have been shown to play important biological roles. Here, the authors show that at the ER, PDZD8 associates with Protrudin and also with Rab7 endosomes and recruits mitochondria to form three-way contacts.
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Publication date: Available online 20 July 2020Source: Sleep MedicineAuthor(s): Samu Kainulainen, Juha Töyräs, Arie Oksenberg, Henri Korkalainen, Isaac O. Afara, Akseli Leino, Laura Kalevo, Sami Nikkonen, Natan Gadoth, Antti Kulkas, Sami Myllymaa, Timo Leppänen
Mon Jul 20, 2020 13:54
Publication date: Available online 19 July 2020Source: Sleep MedicineAuthor(s): Mei Ling Song, Kyung Min Park, Gholam K. Motamedi, Yong Won Cho
Mon Jul 20, 2020 13:54
Publication date: Available online 19 July 2020Source: Sleep MedicineAuthor(s): Kendra N. Krietsch, Christopher D. King, Dean W. Beebe
Mon Jul 20, 2020 13:54
Abstract Purpose Our previous cross-sectional study showed that periodic limb movements during sleep (PLMS) were frequently found in patients with obstructive sleep apnea (OSA) and that both OSA and PLMS were associated with higher plasma fibrinogen levels. We explored the longitudinal relationships among these factors. Methods Plasma fibrinogen levels...
Mon Jul 20, 2020 03:00
Treatment for Brodie's abscess of the radius in an adolescent: A case report. Int J Surg Case Rep. 2020 Jul 10;73:134-140 Authors: Ushijima T, Arai K Abstract INTRODUCTION: Brodie's abscess is an uncommon type subacute osteomyelitis. It is typically localized in the metaphysis of tubular bones, particularly in the lower extremities. We herein report a rare case of the abscess appearing in the upper extremities. Furthermore, we successfully...
Mon Jul 20, 2020 13:53
Treatment of complex complications after choledochal cyst resection by multiple minimal invasive therapies: A case report. Int J Surg Case Rep. 2020 Jul 11;73:130-133 Authors: Nguyen HV, Do DH, Nguyen HV, Vu TH, Hong QQ, Vo CT, Dang THT, Nguyen NB, Le DT, Tran PH, Nguyen LT Abstract INTRODUCTION: Choledochal cyst is a rare benign congenital dilation of the bile duct, which causes recurring disturbing symptoms without totally resection. Nonetheless,...
Mon Jul 20, 2020 13:53
Common iliac artery aneurysm as a cause of massive hematuria post TURBT. Case report. Int J Surg Case Rep. 2020 Jul 11;73:121-124 Authors: Alkhatatbeh H, Alzaghari D, Alharahsheh S, Azab M, Almalkawi A, Alnsour R, ALsamen AAA Abstract INTRODUCTION: Transurethral resection of bladder tumor (TURBT) is an outpatient simple procedure that aims to remove bladder masses. Bleeding post TURBT is usually minimal and resolve completely within days or...
Mon Jul 20, 2020 13:53
Publication date: October 2020Source: International Immunopharmacology, Volume 87Author(s): Lijuan Lyu, Yi Zheng, Yun Hong, Meng Wang, Yujiao Deng, Ying Wu, Peng Xu, Si Yang, Shuqian Wang, Jia Yao, Dai Zhang, Yan Guo, Jun Lyu, Zhijun Dai
Mon Jul 20, 2020 13:52
Traumatic fetal subdural hematoma and unstable maternal spine fracture. World Neurosurg. 2020 Jul 16;: Authors: Young CC, Hofstetter CP Abstract We present a remarkable image of a woman, 24-weeks pregnant, who sustained polytrauma following a high-speed motor vehicle collision. Evaluation revealed traumatic bilateral subdural hematoma in the fetus and an unstable T12/L1 fracture in the patient. The standard of care for her unstable fracture...
Mon Jul 20, 2020 13:52
Intracranial-Intracranial Bypass Using a "Y"-Shaped Artery Graft for Growing Unruptured Gemella Morbillorum Infectious Aneurysm on Artery Supplying Sensory Cortex: A Case Report. World Neurosurg. 2020 Jul 16;: Authors: Shiba M, Toma N, Ikezawa M, Kuroda Y, Suzuki Y, Asada R, Miura Y, Yasuda R, Suzuki H Abstract BACKGROUND: Vascular reconstruction is required to treat infectious intracranial aneurysms (IIAs) on arteries supplying the eloquent...
Mon Jul 20, 2020 13:52
Rescue Surgery in the Flow Diverter Era: Partial Trapping plus Revascularization Technique for a Giant Carotid-Ophthalmic Aneurysm. World Neurosurg. 2020 Jul 16;: Authors: Torné R, Rodríguez-Hernández A, Tercero-Uribe A, Hurtado P, López-Rueda A, Poblete J, Enseñat J Abstract BACKGROUND: Flow-diverters (FDD) are an excellent option for the management of giant carotid artery aneurysms. However, in a non-negligible percent of cases, the aneurysm...
Mon Jul 20, 2020 13:52
Spontaneous Resolution of Dural and Pial Arteriovenous Fistulae Arising after Superficial Temporal Artery to Middle Cerebral Artery Bypass for Moyamoya Disease. World Neurosurg. 2020 Jul 16;: Authors: Peeters SM, Colby GP, Guivatchian E, Sun MZ, Tateshima S, Wang AC Abstract BACKGROUND: Superficial temporal artery (STA) to middle cerebral artery (MCA) bypass is frequently performed for moyamoya disease. We discuss an unusual case in a moyamoya...
Mon Jul 20, 2020 13:52
Adult intracranial myxoid mesenchymal tumor with EWSR1-ATF1 gene fusion. World Neurosurg. 2020 Jul 16;: Authors: Ward B, Wang C, Macaulay RJB, Liu JKC Abstract BACKGROUND: Intracranial myxoid mesenchymal tumors (IMMT) carrying an EWSR1-CREB gene family fusion are extremely rare and have only been identified in ten previous reports. All but one has been found in children or young adults. Although there appear to be similarities a myxoid variant...
Mon Jul 20, 2020 13:52
International medical graduates applying to neurosurgical residency in the United States through the lenses of an applicant versus a program director. World Neurosurg. 2020 Jul 16;: Authors: Lu VM, Chambless LB PMID: 32683004 [PubMed - as supplied by publisher]
Mon Jul 20, 2020 13:52
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