Nutrients, Vol. 12, Pages 2220: Effect of Choline Forms and Gut Microbiota Composition on Trimethylamine-N-Oxide Response in Healthy Men Nutrients doi: 10.3390/nu12082220 Authors: Clara E. Cho Niklas D. J. Aardema Madison L. Bunnell Deanna P. Larson Sheryl S. Aguilar Janet R. Bergeson Olga V. Malysheva Marie A. Caudill Michael Lefevre Background: Trimethylamine-N-oxide (TMAO), a choline-derived gut microbiota-dependent metabolite, is a newly recognized risk marker...
Sat Jul 25, 2020 03:00
Nutrients, Vol. 12, Pages 2219: High Serum Folate Concentration Is Associated with Better Lung Function in Male Chronic Obstructive Pulmonary Disease Patients Who Are Current Smokers: Analysis of Nationwide Population-Based Survey Nutrients doi: 10.3390/nu12082219 Authors: Taeyun Kim Chul-Ho Oak Mann-Hong Jung Tae-Won Jang Jehun Kim Folate, folic acid, has a role in mitigating inflammatory reactions in the human body. This study aimed to evaluate the association of serum...
Sat Jul 25, 2020 03:00
Nutrients, Vol. 12, Pages 2222: GLIM Criteria for Malnutrition in Surgical IBD Patients: A Pilot Study Nutrients doi: 10.3390/nu12082222 Authors: Camilla Fiorindi Cristina Luceri Gabriele Dragoni Guya Piemonte Stefano Scaringi Fabio Staderini Anita Nannoni Ferdinando Ficari Francesco Giudici Background: A gold standard method for malnutrition diagnosis is still lacking in Inflammatory Bowel Disease (IBD). Objective: The aims of this study are to determine the...
Sat Jul 25, 2020 03:00
Nutrients, Vol. 12, Pages 2221: B12 as a Treatment for Peripheral Neuropathic Pain: A Systematic Review Nutrients doi: 10.3390/nu12082221 Authors: Thomas Julian Rubiya Syeed Nicholas Glascow Efthalia Angelopoulou Panagiotis Zis Neuropathic pain describes a range of unpleasant sensations caused by a lesion or disease of the somatosensory nervous system. The sensations caused by neuropathic pain are debilitating and improved treatment regimens are sought in order to improve...
Sat Jul 25, 2020 03:00
Nutrients, Vol. 12, Pages 2223: Ingestion of Carbohydrate Prior to and during Maximal, Sprint Interval Cycling Has No Ergogenic Effect: A Randomized, Double-Blind, Placebo Controlled, Crossover Study Nutrients doi: 10.3390/nu12082223 Authors: Gerard McMahon Aaron Thornbury Carbohydrate (CHO) ingestion may improve intermittent sprint performance in repeated sprint efforts ≤15 s. Yet, evidence for its efficacy on sprint interval durations ~30 s is lacking. The purpose of this...
Sat Jul 25, 2020 03:00
Nutrients, Vol. 12, Pages 2218: Comparative Effect of Statins and Omega-3 Supplementation on Cardiovascular Events: Meta-Analysis and Network Meta-Analysis of 63 Randomized Controlled Trials Including 264,516 Participants Nutrients doi: 10.3390/nu12082218 Authors: Hoang Kim Statins and omega-3 supplementation have been recommended for cardiovascular disease prevention, but comparative effects have not been investigated. This study aimed to summarize current evidence of the effect...
Sat Jul 25, 2020 03:00
Nutrients, Vol. 12, Pages 2217: Main Factors Influencing Whole Grain Consumption in Children and Adults—A Narrative Review Nutrients doi: 10.3390/nu12082217 Authors: Alexandra Meynier Aurélie Chanson-Rollé Elisabeth Riou Despite their recognized health benefits, intakes of whole grains (WG) are below recommended levels in almost all countries worldwide. This observation highlights the need to increase WG consumption by understanding factors influencing this consumption and how...
Sat Jul 25, 2020 03:00
Nutrients, Vol. 12, Pages 2216: Adverse Impact of Desulfovibrio spp. and Beneficial Role of Anaerostipes spp. on Renal Function: Insights from a Mendelian Randomization Analysis Nutrients doi: 10.3390/nu12082216 Authors: Mohsen Mazidi Niloofar Shekoohi Adrian Covic Dimitri P. Mikhailidis Maciej Banach Background: The microbiota composition is now considered as one of the main modifiable risk factors for health. No controlled study has been performed on the association between...
Sat Jul 25, 2020 03:00
Nutrients, Vol. 12, Pages 2215: Overfeeding and Substrate Availability, but Not Age or BMI, Alter Human Satellite Cell Function Nutrients doi: 10.3390/nu12082215 Authors: Dane W. Fausnacht Ryan P. McMillan Nabil E. Boutagy Ryan A. Lupi Mordecai M. Harvey Brenda M. Davy Kevin P. Davy Robert P. Rhoads Matthew W. Hulver Satellite cells (SC) aid skeletal muscle growth and regeneration. SC-mediated skeletal muscle repair can both be influenced by and exacerbate several...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2214: What Healthcare Professionals Think of “Nutrition & Diet” Apps: An International Survey Nutrients doi: 10.3390/nu12082214 Authors: Maria F. Vasiloglou Stergios Christodoulidis Emilie Reber Thomai Stathopoulou Ya Lu Zeno Stanga Stavroula Mougiakakou Accurate dietary assessment is crucial for both the prevention and treatment of nutrition-related diseases. Since mobile-based dietary assessment solutions are promising, we sought to examine...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2212: Mediterranean Diet and Endothelial Function: A Review of Its Effects at Different Vascular Bed Levels Nutrients doi: 10.3390/nu12082212 Authors: Jose D. Torres-Peña Oriol A. Rangel-Zuñiga Juan F. Alcala-Diaz Jose Lopez-Miranda Javier Delgado-Lista The Mediterranean diet has recently been the focus of considerable attention as a palatable model of a healthy diet. Its influence on many cardiovascular risk factors, combined with its proven effect...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2213: Salt Reduction Strategies in Portuguese School Meals, from Pre-School to Secondary Education—The Eat Mediterranean Program Nutrients doi: 10.3390/nu12082213 Authors: Ana Isabel Rito Sofia Mendes Mariana Santos Francisco Goiana-da-Silva Francesco Paolo Cappuccio Stephen Whiting Ana Dinis Carla Rascôa Isabel Castanheira Ara Darzi João Breda High sodium (salt) consumption is associated with an increased risk of developing non-communicable...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2210: Effect of the Flipped Classroom and Gamification Methods in the Development of a Didactic Unit on Healthy Habits and Diet in Primary Education Nutrients doi: 10.3390/nu12082210 Authors: Gerardo Gómez-García José Antonio Marín-Marín José-María Romero-Rodríguez Magdalena Ramos Navas-Parejo Carmen Rodríguez Jiménez Currently, there are several methodological models that have broken into different disciplines of knowledge with the aim of making...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2211: Recovery of Saccharomyces cerevisiae CNCM I-3856 in Vaginal Samples of Healthy Women after Oral Administration Nutrients doi: 10.3390/nu12082211 Authors: Amelie Decherf Elodie Dehay Mickaël Boyer Mathieu Clément-Ziza Bertrand Rodriguez Sophie Legrain-Raspaud Bacterial vaginosis and vulvovaginal candidiasis are common causes of impaired health and quality of life for women. Although antimicrobial agents remain the main strategy for the treatment...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2209: Third-Trimester Glucose Homeostasis in Healthy Women Is Differentially Associated with Human Milk Oligosaccharide Composition at 2 Months Postpartum by Secretor Phenotype Nutrients doi: 10.3390/nu12082209 Authors: Jessica L. Saben Ann Abraham Lars Bode Clark R. Sims Aline Andres Human milk oligosaccharides (HMOs) are bioactive molecules in human milk that play a critical role in infant health. Obesity and associated metabolic aberrations can...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2208: Effects of Lifestyle Modification Interventions to Prevent and Manage Child and Adolescent Obesity: A Systematic Review and Meta-Analysis Nutrients doi: 10.3390/nu12082208 Authors: Rehana A. Salam Zahra A. Padhani Jai K. Das Amina Y. Shaikh Zahra Hoodbhoy Sarah Masroor Jeelani Zohra S. Lassi Zulfiqar A. Bhutta The objective of this review was to assess the impact of lifestyle interventions (including dietary interventions, physical...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2206: Early-Life Supplementation of Bovine Milk Osteopontin Supports Neurodevelopment and Influences Exploratory Behavior Nutrients doi: 10.3390/nu12082206 Authors: Sangyun Joung Joanne E. Fil Anne B. Heckmann Anne S. Kvistgaard Ryan N. Dilger Introduction: Osteopontin (OPN) is a whey protein found at high concentration in human milk and is involved in processes such as bone cell proliferation and differentiation. Milk OPN has shown to be involved...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2205: Uniformity of Food Protein Interpretation Amongst Dietitians for Patients with Phenylketonuria (PKU): 2020 UK National Consensus Statements Nutrients doi: 10.3390/nu12082205 Authors: Sharon Evans Sarah Adam Sandra Adams Heather Allen Catherine Ashmore Sarah Bailey Janette Banks Harriet Churchill Barbara Cochrane Jennifer Cook Clare Dale Anne Daly Marjorie Dixon Carolyn Dunlop Charlotte Ellerton Anita Emm Sarah...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2207: Effect of Food with Low Enrichment of N-3 Fatty Acids in a Two-Month Diet on the Fatty Acid Content in the Plasma and Erythrocytes and on Cardiovascular Risk Markers in Healthy Young Men Nutrients doi: 10.3390/nu12082207 Authors: Martin Jaček Dana Hrnčířová Jolana Rambousková Pavel Dlouhý Petr Tůma Polyunsaturated fatty acids of the n-3 series (n-3 PUFA) exhibit a number of favorable effects on the human organism and it is desirable to increase...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2204: The Impact of Dietary Glycemic Index and Glycemic Load on Postprandial Lipid Kinetics, Dyslipidemia and Cardiovascular Risk Nutrients doi: 10.3390/nu12082204 Authors: Vaia Lambadiari Emmanouil Korakas Vasilios Tsimihodimos Many recent studies have acknowledged postprandial hypetriglyceridemia as a distinct risk factor for cardiovascular disease. This dysmetabolic state is the result of the hepatic overproduction of very low-density lipoproteins (VLDLs)...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2203: A Dairy Product to Reconstitute Enriched with Bioactive Nutrients Stops Bone Loss in High-Risk Menopausal Women without Pharmacological Treatment Nutrients doi: 10.3390/nu12082203 Authors: Marina Morato-Martínez Bricia López-Plaza Cristina Santurino Samara Palma-Milla Carmen Gómez-Candela Osteoporosis is a multifactorial disease characterized by the loss of bone mass and deterioration of the internal structure of the bone, increasing the risk...
Fri Jul 24, 2020 03:00
Nutrients, Vol. 12, Pages 2202: Failure to Thrive in the Outpatient Clinic: A New Insight Nutrients doi: 10.3390/nu12082202 Authors: Antonella Lezo Letizia Baldini Monica Asteggiano Failure to thrive (FTT) is an abnormal growth pattern determined by inadequate nutrition. It is a common problem in children, representing 5% to 10% of patients seen in an outpatient setting. Many definitions have been proposed based on anthropometric deterioration; however, they show poor concordance....
Fri Jul 24, 2020 03:00
Pathogens, Vol. 9, Pages 607: MCMV Dissemination from Latently-Infected Allografts Following Transplantation into Pre-Tolerized Recipients Pathogens doi: 10.3390/pathogens9080607 Authors: Sahil Shah Matthew DeBerge Andre Iovane Shixian Yan Longhui Qiu Jiao-Jing Wang Yashpal S. Kanwar Mary Hummel Zheng J. Zhang Michael M. Abecassis Xunrong Luo Edward B. Thorp Transplantation tolerance is achieved when recipients are unresponsive to donor alloantigen yet...
Sun Jul 26, 2020 03:00
Pathogens, Vol. 9, Pages 606: Molecular Characterization and Pathogenicity of Chicken Parvovirus (ChPV) in Specific Pathogen-Free Chicks Infected Experimentally Pathogens doi: 10.3390/pathogens9080606 Authors: Luis Fabian N. Nuñez Silvana H. Santander-Parra David I. De la Torre Lilian R. M. de Sá Marcos R. Buim Claudete S. Astolfi-Ferreira Antonio J. Piantino Ferreira Chicken parvovirus (ChPV) is an agent frequently associated with runting stunting syndrome (RSS). This...
Sat Jul 25, 2020 03:00
Pathogens, Vol. 9, Pages 605: Control of Persistent Salmonella Infection Relies on Constant Thymic Output Despite Increased Peripheral Antigen-Specific T Cell Immunity Pathogens doi: 10.3390/pathogens9080605 Authors: J. Alan Goggins Jonathan R Kurtz James B. McLachlan Recent thymic emigrants are the youngest subset of peripheral T cells and their involvement in combating persistent bacterial infections has not been explored. Here, we hypothesized that CD4+ recent thymic emigrants...
Sat Jul 25, 2020 03:00
Pathogens, Vol. 9, Pages 604: Health Surveillance of Wild Brown Trout (Salmo trutta fario) in the Czech Republic Revealed a Coexistence of Proliferative Kidney Disease and Piscine Orthoreovirus-3 Infection Pathogens doi: 10.3390/pathogens9080604 Authors: Pojezdal Adamek Syrová Steinhagen Minářová Papežíková Seidlová Reschová Palíková The population of brown trout (Salmo trutta fario) in continental Europe is on the decline, with infectious diseases confirmed...
Fri Jul 24, 2020 03:00
Pathogens, Vol. 9, Pages 603: FCoV Viral Sequences of Systemically Infected Healthy Cats Lack Gene Mutations Previously Linked to the Development of FIP Pathogens doi: 10.3390/pathogens9080603 Authors: Mirjam Lutz Aline R. Steiner Valentino Cattori Regina Hofmann-Lehmann Hans Lutz Anja Kipar Marina L. Meli Feline infectious peritonitis (FIP)—the deadliest infectious disease of young cats in shelters or catteries—is induced by highly virulent feline...
Fri Jul 24, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 166: Immune Pathogenesis of COVID-19 Intoxication: Storm or Silence?
Pharmaceuticals, Vol. 13, Pages 166: Immune Pathogenesis of COVID-19 Intoxication: Storm or Silence? Pharmaceuticals doi: 10.3390/ph13080166 Authors: Mikhail Kiselevskiy Irina Shubina Irina Chikileva Suria Sitdikova Igor Samoylenko Natalia Anisimova Kirill Kirgizov Amina Suleimanova Tatyana Gorbunova Svetlana Varfolomeeva Dysregulation of the immune system undoubtedly plays an important and, perhaps, determining role in the COVID-19 pathogenesis. While the...
Sun Jul 26, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 165: Population-Based Registry Analysis of Antidiabetics Dispensations: Trend Use in Spain between 2015 and 2018 with Reference to Driving Pharmaceuticals doi: 10.3390/ph13080165 Authors: Eduardo Gutiérrez-Abejón Paloma Criado-Espegel Francisco Herrera-Gómez F. Javier Álvarez Insulins and some oral antidiabetics are considered to be driving-impairing medicines (DIM) and they belong to the Driving under the Influence of Drugs, alcohol, and medicines...
Sat Jul 25, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 164: Phenotypic Screening in C. elegans as a Tool for the Discovery of New Geroprotective Drugs Pharmaceuticals doi: 10.3390/ph13080164 Authors: Bulterijs P. Braeckman Population aging is one of the largest challenges of the 21st century. As more people live to advanced ages, the prevalence of age-related diseases and disabilities will increase placing an ever larger burden on our healthcare system. A potential solution to this conundrum is to develop...
Sat Jul 25, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 163: Sevanol and Its Analogues: Chemical Synthesis, Biological Effects and Molecular Docking Pharmaceuticals doi: 10.3390/ph13080163 Authors: Belozerova Osmakov Vladimirov Koshelev Chugunov Andreev Palikov Palikova Shaykhutdinova Gvozd Dyachenko Efremov Kublitski Kozlov Among acid-sensing ion channels (ASICs), ASIC1a and ASIC3 subunits are the most widespread and prevalent in physiological and pathophysiological...
Fri Jul 24, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 162: A Solid Ultra Fine Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) of Deferasirox for Improved Solubility: Optimization, Characterization, and In vitro Cytotoxicity Studies Pharmaceuticals doi: 10.3390/ph13080162 Authors: Alghananim Özalp Mesut Serakinci Özsoy Güngör The research work was designed to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of deferasirox (DFX). According to the solubility studies...
Fri Jul 24, 2020 03:00
Pharmaceuticals, Vol. 13, Pages 161: Piperazine- and Piperidine-Containing Thiazolo[5,4-d]pyrimidine Derivatives as New Potent and Selective Adenosine A2A Receptor Inverse Agonists Pharmaceuticals doi: 10.3390/ph13080161 Authors: Flavia Varano Daniela Catarzi Erica Vigiani Fabrizio Vincenzi Silvia Pasquini Katia Varani Vittoria Colotta The therapeutic use of A2A adenosine receptor (AR) antagonists for the treatment of neurodegenerative disorders, such as Parkinson and...
Fri Jul 24, 2020 03:00
Pharmaceutics, Vol. 12, Pages 705: Development of New Strategies Using Extracellular Vesicles Loaded with Exogenous Nucleic Acid Pharmaceutics doi: 10.3390/pharmaceutics12080705 Authors: Nicola Salvatore Orefice Gene therapy is a therapeutic strategy of delivering foreign genetic material (encoding for an important protein) into a patient’s target cell to replace a defective gene. Nucleic acids are embedded within the adeno-associated virus (AAVs) vectors; however, preexisting...
Sun Jul 26, 2020 03:00
Pharmaceutics, Vol. 12, Pages 704: Enhanced Corneal Penetration of a Poorly Permeable Drug Using Bioadhesive Multiple Microemulsion Technology Pharmaceutics doi: 10.3390/pharmaceutics12080704 Authors: Ibrahim Maria Wang Simpson Hollingsworth Jablonski Corneal penetration is a key rate limiting step in the bioavailability of topical ophthalmic formulations that incorporate poorly permeable drugs. Recent advances have greatly aided the ocular delivery of such drugs...
Sun Jul 26, 2020 03:00
Pharmaceutics, Vol. 12, Pages 702: Micelles of Progesterone for Topical Eye Administration: Interspecies and Intertissues Differences in Ex Vivo Ocular Permeability Pharmaceutics doi: 10.3390/pharmaceutics12080702 Authors: Adrián M. Alambiaga-Caravaca María Aracely Calatayud-Pascual Vicent Rodilla Angel Concheiro Alicia López-Castellano Carmen Alvarez-Lorenzo Progesterone (PG) may provide protection to the retina during retinitis pigmentosa, but its topical ocular supply...
Sun Jul 26, 2020 03:00
Pharmaceutics, Vol. 12, Pages 703: Intravitreal Dexamethasone Implant as a Sustained Release Drug Delivery Device for the Treatment of Ocular Diseases: A Comprehensive Review of the Literature Pharmaceutics doi: 10.3390/pharmaceutics12080703 Authors: Claudio Iovino Rodolfo Mastropasqua Marco Lupidi Daniela Bacherini Marco Pellegrini Federico Bernabei Enrico Borrelli Riccardo Sacconi Adriano Carnevali Rossella D’Aloisio Alessio Cerquaglia Lucia Finocchio Andrea...
Sun Jul 26, 2020 03:00
Pharmaceutics, Vol. 12, Pages 701: State of the Art Biocompatible Gold Nanoparticles for Cancer Theragnosis Pharmaceutics doi: 10.3390/pharmaceutics12080701 Authors: Kang Lee Kim Han Research on cancer theragnosis with gold nanoparticles (AuNPs) has rapidly increased, as AuNPs have many useful characteristics for various biomedical applications, such as biocompatibility, tunable optical properties, enhanced permeability and retention (EPR), localized surface plasmon resonance...
Sat Jul 25, 2020 03:00
Pharmaceutics, Vol. 12, Pages 700: Polymer Nanomedicines with Ph-Sensitive Release of Dexamethasone for the Localized Treatment of Inflammation Pharmaceutics doi: 10.3390/pharmaceutics12080700 Authors: Libánská Randárová Lager Renault Scherman Etrych Polymer-drug conjugates have several advantages in controlled drug delivery to inflammation as they can accumulate and release the drug in inflamed tissues or cells, which could circumvent the shortcomings of current...
Sat Jul 25, 2020 03:00
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