RECENT TECHNICAL ADVANCEMENTS OF ENDOSCOPIC SPINE SURGERY WITH DISPARATE OR DISRUPTIVE TECHNOLOGIES AND PATENTS. World Neurosurg. 2020 Jul 16;: Authors: Akbary K, Kim JS PMID: 32683003 [PubMed - as supplied by publisher]
Caudal regression syndrome (Spinal thoraco-lumbo-sacro-coccygeal agenesis). World Neurosurg. 2020 Jul 16;: Authors: Akhaddar A Abstract This is a case report of a 2-year-old male presented with walking disability and sphincter incontinence since birth. His mother has a diabetes mellitus. The patient had a normal mental function and his lower extremities were hypoplastic and akinetic. Spinal neuroimaging investigations revealed agenesis of the...
Stepping Up: How United States Neurosurgery Training Programs Can Innovatively Assess Resident Applicants in a Post-Step 1 World. World Neurosurg. 2020 Jul 16;: Authors: Bhandarkar AR, Graffeo CS, Johnson J PMID: 32683001 [PubMed - as supplied by publisher]
Individualized Prediction of Overall Survival for Primary Intramedullary Spinal Cord Grade II/III Ependymoma. World Neurosurg. 2020 Jul 16;: Authors: Wang C, Yuan X, Zuo J Abstract OBJECTIVE: The purpose of this study was to develop and validate a nomogram to predict overall survival (OS) for adult patients with primary intramedullary spinal cord grade II/III ependymoma (PISCGE). We also elucidated the effectiveness of postoperative radiotherapy...
Intraoperative head slippage with the head clamp system may occur during epileptic surgery. World Neurosurg. 2020 Jul 16;: Authors: Sakakura K, Fujimoto A, Ishikawa E, Enoki H, Okanishi T Abstract BACKGROUND: During neurosurgery, we use a head clamp system for firm head fixation. We have faced slippage with the head clamp system, but this has not been adequately studied. In this study, to increase the reliability of analysis using a more homogeneous...
Effect of Comorbid Depression on Surgical Outcomes Following Craniotomy for Malignant Brain Tumors: A Nationwide Readmission Database Analysis. World Neurosurg. 2020 Jul 16;: Authors: Rumalla K, Lin M, Orloff E, Ding L, Zada G, Mack W, Attenello F Abstract OBJECTIVE: Quality of life is paramount in advanced cancer patients and may be adversely affected by comorbid depression. We hypothesized that comorbid depression is associated with higher...
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Clinical impact of follicular oncocytic (Hürthle cell) carcinoma in comparison with corresponding classical follicular thyroid carcinoma. Eur J Nucl Med Mol Imaging. 2020 Jul 18;: Authors: Wenter V, Albert NL, Unterrainer M, Ahmaddy F, Ilhan H, Jellinek A, Knösel T, Bartenstein P, Spitzweg C, Lehner S, Todica A Abstract PURPOSE: There are controversial debates if patients with Hürthle cell carcinoma, also known as oxyphilic or oncocytic...
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Publication date: Available online 19 July 2020Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): M.A. Mashrah, T.A. Aldhohrah, A. Abdelrehem Moustafa, H.M. Al-Sharani, A. Alrmali, L. Wang
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The novel corona virus and rhinology: Impact on practice patterns and future directions. Am J Otolaryngol. 2020 Jun 01;41(6):102569 Authors: Setzen M, Svider PF, Setzen S, Setzen G, Eloy JA, Johnson AP Abstract OBJECTIVES: To evaluate the impact of the novel coronavirus pandemic on practice patterns, clinical behavior, personal health, and emotional/psychological concerns of rhinologists. METHODS: A 15-question survey was sent out...
Fabrication of chitosan/polyvinylpyrrolidone hydrogel scaffolds containing PLGA microparticles loaded with dexamethasone for biomedical applications. Int J Biol Macromol. 2020 Jul 16;: Authors: Garakani SS, Davachi SM, Bagher Z, Esfahani AH, Jenabi N, Atoufi Z, Khanmohammadi M, Abbaspourrad A, Rashedi H, Jalessi M Abstract One of the most effective approaches for treatment of chronic rhinosinusitis is the use of hydrogel scaffolds with the...
Pulsatile tinnitus caused by an aberrant artery running over the surface of mastoid bone. Auris Nasus Larynx. 2020 Jul 15;: Authors: Hsieh YL, Xu X, Guo P, Wang W Abstract OBJECTIVE: Pulsatile tinnitus (PT) caused by an aberrant artery is rare. We report an unprecedented cause of PT resulting from an aberrant artery coursing the mastoid surface, and qualitatively discuss the pathophysiology of PT. METHODS: This case study reports a...
Role of craniofacial surgery in oral and maxillofacial tumors involving the skull base: A retrospective analysis of 126 patients. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Jun 17;: Authors: Yang L, Li JY, Xiao YD, Deng W, Qiao YJ, Liang YJ, Liao GQ Abstract OBJECTIVES: Oral and maxillofacial tumors involving the skull base (SB) are rare and complex, making treatment difficult and controversial. The purpose of the present study was to...
Perioperative Pain Management Following Otologic Surgery. Otolaryngol Clin North Am. 2020 Jul 15;: Authors: Morrison DR, Moore LS, Walsh EM Abstract Otologic surgery involves a broad range of procedures. In general, postoperative pain from most otologic surgeries can be managed with little to no opioids, and surgeons should make a concerted effort to minimize narcotic prescriptions in the midst of the opioid crisis. Many procedures, including...
Pain Management for the Otolaryngologist: Overview of Perioperative Analgesia and Introduction to Opioids. Otolaryngol Clin North Am. 2020 Jul 15;: Authors: Svider PF, Pashkova AA, Eloy JA Abstract Nearly 50,000 US adults experience opioid-overdose deaths annually and 1.7 million experience a substance use disorder from prescription opioids. Hence, understanding analgesia strategies is of utmost importance. A pre-operative analgesic plan can...
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Unexpected endometrial malacoplakia related to abortion and placental rests retention: a case report. Diagn Pathol. 2020 Jul 18;15(1):88 Authors: d'Amati A, Bellitti E, Resta L Abstract BACKGROUND: Malacoplakia is a rare chronic inflammatory disease. The name derives from the Greek "μαλακός" meaning "soft" and "πλάξ" meaning "plaque", describing its usual macroscopic presentation as a friable yellow soft plaque. It was first described by von...
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Superior sagittal sinus thrombosis after spinal anesthesia. Neurosciences (Riyadh). 2020 Jul;25(3):210-213 Authors: Daqqaq TS, Naqshabandi AA, Rajih ES Abstract Superior sagittal sinus thrombosis is an uncommon phenomenon that could occur in patients with a risk for thrombosis. It has been reported after spinal anesthesia with persistent cerebrospinal fluid leak. The current case is a young 29-year-old man who was complaining of persistent...
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Abstract Introduction Vandetanib is indicated for adults with advanced medullary thyroid cancer (MTC). Objectives To describe the efficacy and toxicity profile of vandetanib treatment with a maximal follow-up of 11 years at Institut Gustave Roussy/France. Methods ...
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Risk of cerebrovascular disease among 13,457 five-year survivors of childhood cancer: a population based cohort study. Int J Cancer. 2020 Jul 19;: Authors: Reulen RC, Guha J, Bright CJ, Henson KE, Feltbower RG, Hall M, Kelly JS, Winter DL, Kwok-Williams M, Skinner R, Cutter DJ, Frobisher C, Hawkins MM Abstract Survivors of childhood cancer treated with cranial irradiation are at risk of cerebrovascular disease (CVD), but the risks beyond...
The "unnatural" history of colorectal cancer in Lynch syndrome: lessons from colonoscopy surveillance. Int J Cancer. 2020 Jul 19;: Authors: Ahadova A, Seppälä TT, Engel C, Gallon R, Burn J, Holinski-Feder E, Steinke-Lange V, Möslein G, Nielsen M, Ten Broeke S, Laghi L, Dominguez-Valentin M, Capella G, Macrae F, Scott R, Hüneburg R, Nattermann J, Hoffmeister M, Brenner H, Bläker H, von Knebel Doeberitz M, Sampson JR, Vasen H, Mecklin JP, Møller P, Kloor M...
Resilience process and its protective factors in long-term survivors after lung cancer surgery: a qualitative study. Support Care Cancer. 2020 Jul 18;: Authors: Li X, Chen S, Zhang J, Li L, Li Y, Ye M Abstract BACKGROUND: Resilience was correlated with psychological outcomes and quality of life in lung cancer patients. But the resilience process and its protective factors remained uncertain. PURPOSE: To investigate and analyze...
The FLUKA Monte Carlo code coupled with an OER model for biologically weighted dose calculations in proton therapy of hypoxic tumors. Phys Med. 2020 Jul 16;76:166-172 Authors: Dahle TJ, Rusten E, Stokkevåg CH, Silvoniemi A, Mairani A, Fjæra LF, Rørvik E, Henjum H, Wright P, Boer CG, Forsback S, Minn H, Malinen E, Ytre-Hauge KS Abstract INTRODUCTION: The increased radioresistance of hypoxic cells compared to well-oxygenated cells is quantified...
Best practice in reducing the suicide risk in head and neck cancer patients: a structured review. Br J Oral Maxillofac Surg. 2020 Jul 15;: Authors: Twigg JA, Anderson JM, Humphris G, Nixon I, Rogers SN, Kanatas A Abstract The treatment of head and neck cancer (HNC) is often radical and the patient's journey challenging, especially for individuals who are struggling with pre-existing mental health problems and who lack social support. Patients...
Postoperative recovery of accelerometer-based physical activity in older cancer patients. Eur J Surg Oncol. 2020 Jun 24;: Authors: Jonker LT, Hendriks S, Lahr MM, van Munster BC, de Bock GH, van Leeuwen BL Abstract INTRODUCTION: Recovery of physical activity is an important functional outcome measure after cancer surgery. However, objective data on physical activity for older cancer patients is scarce. The aims of this study were to quantify...
Patients' confidence in treatment decisions for early stage non-small cell lung cancer (NSCLC). Health Qual Life Outcomes. 2020 Jul 18;18(1):237 Authors: Pompili C, Holch P, Rogers Z, Absolom K, Clayton B, Franks K, Bekker H, Velikova G Abstract BACKGROUND: In early-stage Non-Small Cell Lung Cancer (NSCLC) patients, little is known about how to measure patient participation in Shared-Decision Making (SDM). We examined the psychometric...
Transient Hepatotoxicity Induced by Vinblastine in a Young Girl with Chiasmatic low Grade Glioma. Curr Drug Saf. 2020 Jul 18;: Authors: Franke NE, Blok GJ, Voll ML, Schouten-van Meeteren AY Abstract BACKGROUND: Vinblastine (VBL) is a cytostatic drug frequently applied in children with lymphoma and progressive low-grade glioma (LGG) in children, with hematotoxicity as main side effect. CASE REPORT: Here we present a 7-month-old...
The Influence of Different Disease States on Rituximab Pharmacokinetics. Curr Drug Metab. 2020 Jul 18;: Authors: Wang X, Du W, Zhang X, Li P Abstract BACKGROUND: The anti-CD20 antibody rituximab, which promotes the selective depletion of CD20 positive B cells, was the first targeted therapy that was approved for the treatment of B-cell malignancies, and it is now widely prescribed in both malignant and non-malignant, immune-related diseases....
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Publication date: September 2020Source: Journal of Phonetics, Volume 82Author(s): Sam Tilsen
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Bifenthrin impairs the functions of Leydig and Sertoli cells in mice via mitochondrion-endoplasmic reticulum dysregulation. Environ Pollut. 2020 Jul 11;266(Pt 3):115174 Authors: Ham J, You S, Lim W, Song G Abstract Bifenthrin (BF) is a synthetic insecticide that is widely used in fields, resulting in an increase in its exposure to animals. However, reports on the toxic effects of BF on mammalian species and the underlying mechanism are...
Berberine and Emodin abrogates breast cancer growth and facilitates apoptosis through inactivation of SIK3-induced mTOR and Akt signaling pathway. Biochim Biophys Acta Mol Basis Dis. 2020 Jul 16;:165897 Authors: Ponnusamy L, Kothandan G, Manoharan R Abstract Salt-inducible kinases 3 (SIK3) belong to the AMPK-related family of kinases, which have been implicated in the regulation of cell metabolism, cell polarity remodelling, and epithelial-mesenchymal...
Anlotinib Inhibits Cell Proliferation, Migration and Invasion via Suppression of c-met Pathway and Activation of ERK1/2 Pathway in H446 Cells. Anticancer Agents Med Chem. 2020 Jul 18;: Authors: Tang X, Zheng Y, Jiao D, Chen J, Liu X, Xiong S, Chen Q Abstract BACKGROUND: Small Cell Lung Cancer (SCLC) represents the most aggressive pulmonary neoplasm and is often diagnosed at late stage with limited survival, despite combined chemotherapies....
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Publication date: Available online 20 July 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Allinovi Marco, Parise Alberto, Giacalone Martina, Amerio Andrea, Delsante Marco, Odone Anna, Franci Andrea, Gigliotti Fabrizio, Amadasi Silvia, Delmonte Davide, Parri Niccolò, Mangia Angelo
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An Invited Commentary on "The efficacy and safety of low dialysate sodium levels for patients with maintenance hemodialysis" (Int J Surg 2020; Epub ahead of Print). Int J Surg. 2020 Jul 16;: Authors: Alvarez-Garcia L, Sanchez-Villanueva RJ PMID: 32682978 [PubMed - as supplied by publisher]
Invited Commentary on "Initial Surgical versus Non-Surgical treatments for advanced hypopharyngeal cancer; a meta-analysis with trial sequential analysis" (Int J Surg 2020; Epub ahead of Print). Int J Surg. 2020 Jul 16;: Authors: McCaul JA, Nankivell PC, Nutting C PMID: 32682977 [PubMed - as supplied by publisher]
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This article describes the associations between the results of fecal incontinence severity and contemporary anorectal investigations, including high‐resolution anorectal manometry (left), and three‐dimensional endoanal sonography (right). Abstract Background Diagnostic investigations for fecal incontinence (FI) assess the structure and sensorimotor function of the anorectum. Investigations include anorectal manometry, anorectal sensory testing, pudendal nerve terminal motor latencies...
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Abstract At present, the traditional scoring methods generally utilize laboratory measurements to predict mortality. It results in difficulties of early mortality prediction in the rural areas lack of professional laboratorians and medical laboratory equipment. To improve the efficiency, accuracy, and applicability of mortality prediction in the remote areas, a novel mortality prediction method based on machine learning algorithms is proposed, which only uses non-invasive parameters...
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Many researchers in the behavioral sciences depend on research software that presents stimuli, and records response times, with sub-millisecond precision. There are a large number of software packages with which to conduct these behavioral experiments and measure response times and performance of participants. Very little information is available, however, on what timing performance they achieve in practice. Here we report a wide-ranging study looking at the precision and accuracy of visual and auditory...
Baylisascaris procyonis is an important zoonotic nematode of raccoons (Procyon lotor). Infection with this parasite has important health implications for humans, zoo animals, and free-ranging wildlife. As a large, natural habitat zoo, the North Carolina Zoo (NC Zoo) coexists with native wildlife. Raccoons are abundant at the NC Zoo and the prevalence of B. procyonis is unknown. Raccoon latrines were located through employee reporting and systematic searching throughout the zoo and sampled for B....
Safe, efficient and cancer cell targeted delivery of CRISPR/Cas9 is important to increase the effectiveness of available cancer treatments. Although cancer derived exosomes offer significant advantages, the fact that it carries cancer related/inducing signaling molecules impedes them from being used as a reliable drug delivery vehicle. In this study, we report that normal epithelial cell-derived exosomes engineered to have HN3 (HN3LC9-293exo), target tumor cells as efficiently as that of the cancer...
The influenza pandemic causes a large number of hospitalizations and even deaths. There is an urgent need for an efficient and effective method for detecting the outbreak of influenza so that timely, appropriate interventions can be made to prevent or at least prepare for catastrophic epidemics. In this study, we proposed a computational method, the shortest-path-based dynamical network marker (SP-DNM), to detect the pre-outbreak state of influenza epidemics by monitoring the dynamical change of...
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