IJMS, Vol. 21, Pages 5196: Phage S144, A New Polyvalent Phage Infecting Salmonella spp. and Cronobacter sakazakii International Journal of Molecular Sciences doi: 10.3390/ijms21155196 Authors: Michela Gambino Anders Nørgaard Sørensen Stephen Ahern Georgios Smyrlis Yilmaz Emre Gencay Hanne Hendrix Horst Neve Jean-Paul Noben Rob Lavigne Lone Brøndsted Phages are generally considered species- or even strain-specific, yet polyvalent phages are able to infect bacteria...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5193: Rapid Alpha-Synuclein Toxicity in a Neural Cell Model and Its Rescue by a Stearoyl-CoA Desaturase Inhibitor International Journal of Molecular Sciences doi: 10.3390/ijms21155193 Authors: Elizabeth Terry-Kantor Arati Tripathi Thibaut Imberdis Zachary M. LaVoie Gary P. H. Ho Dennis Selkoe Saranna Fanning Nagendran Ramalingam Ulf Dettmer Genetic and biochemical evidence attributes neuronal loss in Parkinson’s disease (PD) and...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5190: Molecular and Functional Analysis of Choline Transporters and Antitumor Effects of Choline Transporter-Like Protein 1 Inhibitors in Human Pancreatic Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms21155190 Authors: Kaho Hirai Saiichiro Watanabe Nozomi Nishijima Kaoru Shibata Akane Hase Tsuyoshi Yamanaka Masato Inazu Choline, an organic cation, is one of the biofactors that play an important role in the structure and...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5189: Sulforaphane Elicits Protective Effects in Intestinal Ischemia Reperfusion Injury International Journal of Molecular Sciences doi: 10.3390/ijms21155189 Authors: Zhiquan Chen Annika Mohr Barbara Heitplatz Uwe Hansen Andreas Pascher Jens G. Brockmann Felix Becker Intestinal ischemia reperfusion injury (IRI) is an inherent, unavoidable event of intestinal transplantation, contributing to allograft failure and rejection. The inflammatory state...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5188: Characterization of Fluid Biomarkers Reveals Lysosome Dysfunction and Neurodegeneration in Neuronopathic MPS II Patients International Journal of Molecular Sciences doi: 10.3390/ijms21155188 Authors: Akhil Bhalla Ritesh Ravi Meng Fang Annie Arguello Sonnet S. Davis Chi-Lu Chiu Jessica R. Blumenfeld Hoang N. Nguyen Timothy K. Earr Junhua Wang Giuseppe Astarita Yuda Zhu Damian Fiore Kimberly Scearce-Levie Dolores Diaz Heather...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5192: B-Cell Maturation Antigen (BCMA) as a Target for New Drug Development in Relapsed and/or Refractory Multiple Myeloma International Journal of Molecular Sciences doi: 10.3390/ijms21155192 Authors: Hanley N. Abramson During the past two decades there has been a major shift in the choice of agents to treat multiple myeloma, whether newly diagnosed or in the relapsed/refractory stage. The introduction of new drug classes, such as proteasome inhibitors, immunomodulators,...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5186: The CCL20-CCR6 Axis in Cancer Progression International Journal of Molecular Sciences doi: 10.3390/ijms21155186 Authors: Suguru Kadomoto Kouji Izumi Atsushi Mizokami Chemokines, which are basic proteins that exert their effects via G protein-coupled receptors and a subset of the cytokine family, are mediators deeply involved in leukocyte migration during an inflammatory reaction. Chemokine (C-C motif) ligand 20 (CCL20), also known as macrophage inflammatory...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5185: Investigating the Vascular Toxicity Outcomes of the Irreversible Proteasome Inhibitor Carfilzomib International Journal of Molecular Sciences doi: 10.3390/ijms21155185 Authors: Panagiotis Efentakis Hendrik Doerschmann Claudius Witzler Svenja Siemer Panagiota-Efstathia Nikolaou Efstathios Kastritis Roland Stauber Meletios Athanasios Dimopoulos Philip Wenzel Ioanna Andreadou Evangelos Terpos Background: Carfilzomib’s (Cfz)...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5187: Optimization of the Preparation of Magnetic Liposomes for the Combined Use of Magnetic Hyperthermia and Photothermia in Dual Magneto-Photothermal Cancer Therapy International Journal of Molecular Sciences doi: 10.3390/ijms21155187 Authors: Anilkumar T. S. Yu-Jen Lu Jyh-Ping Chen In this work, we aimed to develop liposomal nanocomposites containing citric-acid-coated iron oxide magnetic nanoparticles (CMNPs) for dual magneto-photothermal cancer therapy...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5180: Simple and Divided Leaves in Ferns: Exploring the Genetic Basis for Leaf Morphology Differences in the Genus Elaphoglossum (Dryopteridaceae) International Journal of Molecular Sciences doi: 10.3390/ijms21155180 Authors: Vasco Ambrose Despite the implications leaves have for life, their origin and development remain debated. Analyses across ferns and seed plants are fundamental to address the conservation or independent origins of megaphyllous leaf developmental...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5184: Proteome Analysis of Molecular Events in Oral Pathogenesis and Virus: A Review with a Particular Focus on Periodontitis International Journal of Molecular Sciences doi: 10.3390/ijms21155184 Authors: Sachio Tsuchida Some systemic diseases are unquestionably related to periodontal health, as periodontal disease can be an extension or manifestation of the primary disease process. One example is spontaneous gingival bleeding, resulting from anticoagulant treatment...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5183: Assessing Molecular Docking Tools to Guide Targeted Drug Discovery of CD38 Inhibitors International Journal of Molecular Sciences doi: 10.3390/ijms21155183 Authors: Eric D. Boittier Yat Yin Tang McKenna E. Buckley Zachariah P. Schuurs Derek J. Richard Neha S. Gandhi A promising protein target for computational drug development, the human cluster of differentiation 38 (CD38), plays a crucial role in many physiological and pathological processes,...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5181: Immune Checkpoint Expression on Immune Cells of HNSCC Patients and Modulation by Chemo- and Immunotherapy International Journal of Molecular Sciences doi: 10.3390/ijms21155181 Authors: Lisa K. Puntigam Sandra S. Jeske Marlies Götz Jochen Greiner Simon Laban Marie-Nicole Theodoraki Johannes Doescher Stephanie E. Weissinger Cornelia Brunner Thomas K. Hoffmann Patrick J. Schuler Endogenous control mechanisms, including immune checkpoints...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5182: Alterations of STEP46 and STEP61 Expression in the Rat Retina with Age and AMD-Like Retinopathy Development International Journal of Molecular Sciences doi: 10.3390/ijms21155182 Authors: Elizabeth A. Kulikova Oyuna S. Kozhevnikova Alexander V. Kulikov Nataliya G. Kolosova Tatyana M. Khomenko Konstantin P. Volcho Nariman F. Salakhutdinov Darya V. Telegina Tyrosine phosphatase STEP (striatal-enriched tyrosine protein phosphatase) is a brain-specific...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5178: The Time-Feature of Uric Acid Excretion in Hyperuricemia Mice Induced by Potassium Oxonate and Adenine International Journal of Molecular Sciences doi: 10.3390/ijms21155178 Authors: Shaoshi Wen Dan Wang Haiyang Yu Mengyang Liu Qian Chen Ruixia Bao Lin Liu Yi Zhang Tao Wang Hyperuricemia is an important risk factor of chronic kidney disease, metabolic syndrome and cardiovascular disease. We aimed to assess the time-feature relationship...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5179: Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids International Journal of Molecular Sciences doi: 10.3390/ijms21155179 Authors: Gaber El-Saber Batiha Ali Alqahtani Oluwafemi Adeleke Ojo Hazem M. Shaheen Lamiaa Wasef Mahmoud Elzeiny Mahmoud Ismail Mahmoud Shalaby Toshihiro Murata Adrian Zaragoza-Bastida Nallely Rivero-Perez Amany Magdy Beshbishy Keneth Iceland Kasozi Philippe...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5177: Regeneration of Damaged Tendon-Bone Junctions (Entheses)—TAK1 as a Potential Node Factor International Journal of Molecular Sciences doi: 10.3390/ijms21155177 Authors: Nina Friese Mattis Benno Gierschner Patrik Schadzek Yvonne Roger Andrea Hoffmann Musculoskeletal dysfunctions are highly prevalent due to increasing life expectancy. Consequently, novel solutions to optimize treatment of patients are required. The current major research focus is to...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5176: Heterogeneous Polymer Dynamics Explored Using Static 1H NMR Spectra International Journal of Molecular Sciences doi: 10.3390/ijms21155176 Authors: Todd M. Alam Joshua P. Allers Brad H. Jones NMR spectroscopy continues to provide important molecular level details of dynamics in different polymer materials, ranging from rubbers to highly crosslinked composites. It has been argued that thermoset polymers containing dynamic and chemical heterogeneities can...
Wed Jul 22, 2020 03:00
IJMS, Vol. 21, Pages 5175: Early Life Oxidative Stress and Long-Lasting Cardiovascular Effects on Offspring Conceived by Assisted Reproductive Technologies: A Review International Journal of Molecular Sciences doi: 10.3390/ijms21155175 Authors: Huixia Yang Christina Kuhn Thomas Kolben Zhi Ma Peng Lin Sven Mahner Udo Jeschke Viktoria von Schönfeldt Assisted reproductive technology (ART) has rapidly developed and is now widely practised worldwide. Both the characteristics...
Wed Jul 22, 2020 03:00
JCDD, Vol. 7, Pages 26: Phthalates Implications in the Cardiovascular System Journal of Cardiovascular Development and Disease doi: 10.3390/jcdd7030026 Authors: Melissa Mariana Elisa Cairrao Today’s sedentary lifestyle and eating habits have been implicated as some of the causes of the increased incidence of several diseases, including cancer and cardiovascular diseases. However, environmental pollutants have also been identified as another possible cause for this increase...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2342: In Vitro Assessment of Fluoropyrimidine-Metabolizing Enzymes: Dihydropyrimidine Dehydrogenase, Dihydropyrimidinase, and β-Ureidopropionase Journal of Clinical Medicine doi: 10.3390/jcm9082342 Authors: Eiji Hishinuma Evelyn Gutiérrez Rico Masahiro Hiratsuka Fluoropyrimidine drugs (FPs), including 5-fluorouracil, tegafur, capecitabine, and doxifluridine, are among the most widely used anticancer agents in the treatment of solid tumors. However, severe toxicity...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2343: A Cross-Sectional Retrospective Study of Non-Splenectomized and Never-Treated Patients with Type 1 Gaucher Disease Journal of Clinical Medicine doi: 10.3390/jcm9082343 Authors: Serratrice Stirnemann Berrahal Belmatoug Camou Caillaud Billette de Villemeur Dalbies Cador Froissart Masseau Brassier Hivert Swiader Bertchansky de Moreuil Chabrol Durieu Leguy Seguin Astudillo Humbert Pichard...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2340: Clinical Features Associated with Female Genital Mutilation/Cutting: A Pilot Longitudinal Study Journal of Clinical Medicine doi: 10.3390/jcm9082340 Authors: Paslakis Farré Tolosa-Sola Palazón-Llecha Domínguez-Cagnon Jiménez Martínez Rosselló Barri-Soldevila Mestre-Bach (1) Background: Female genital mutilation/cutting (FGM/C) is associated with physical and psychological complications. However, there is scarce literature on...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2341: Targeted Urine Metabolomics for Monitoring Renal Allograft Injury and Immunosuppression in Pediatric Patients Journal of Clinical Medicine doi: 10.3390/jcm9082341 Authors: Tara K. Sigdel Andrew W. Schroeder Joshua Y. C. Yang Reuben D. Sarwal Juliane M. Liberto Minnie M. Sarwal Despite new advancements in surgical tools and therapies, exposure to immunosuppressive drugs related to non-immune and immune injuries can cause slow deterioration and premature...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2339: Hospitalizations for Community-Acquired and Non-Ventilator-Associated Hospital-Acquired Pneumonia in Spain: Influence of the Presence of Bronchiectasis. A Retrospective Database Study Journal of Clinical Medicine doi: 10.3390/jcm9082339 Authors: Gema Sanchez-Muñoz Ana López-de-Andrés Valentín Hernández-Barrera Fernando Pedraza-Serrano Rodrigo Jimenez-Garcia Marta Lopez-Herranz Luis Puente-Maestu Javier de Miguel-Diez To examine and compare...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2338: Outcome of Recipient Surgery and 6-Month Follow-Up of the Swedish Live Donor Robotic Uterus Transplantation Trial Journal of Clinical Medicine doi: 10.3390/jcm9082338 Authors: Brännström Dahm-Kähler Ekberg Akouri Groth Enskog Broecker Mölne Ayoubi Kvarnström Uterus transplantation has proved to be a feasible treatment for uterine factor infertility. Herein, we report on recipient outcome in the robotic uterus transplantation...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2337: New Treatment Options for Hyperkalemia in Patients with Chronic Kidney Disease Journal of Clinical Medicine doi: 10.3390/jcm9082337 Authors: Esposito Conti Falqui Cipriani Picciotto Costigliolo Garibotto Saio Viazzi Hyperkalemia may cause life-threatening cardiac and neuromuscular alterations, and it is associated with high mortality rates. Its treatment includes a multifaceted approach, guided by potassium levels and clinical...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2335: Diagnostic Performances of Urinary Methylmalonic Acid/Creatinine Ratio in Vitamin B12 Deficiency Journal of Clinical Medicine doi: 10.3390/jcm9082335 Authors: Sopak Supakul Floris Chabrun Steve Genebrier Maximilien N’Guyen Guillaume Valarche Arthur Derieppe Adeline Villoteau Valentin Lacombe Geoffrey Urbanski Sole measurement of plasma vitamin B12 is no longer enough to identify vitamin B12 (B12) deficiency. When plasma vitamin B12 is...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2334: The Role of Inflammation and Inflammasome in Myeloproliferative Disease Journal of Clinical Medicine doi: 10.3390/jcm9082334 Authors: Lucia Longhitano Giovanni Li Volti Cesarina Giallongo Mariarita Spampinato Ignazio Barbagallo Michelino Di Rosa Alessandra Romano Roberto Avola Daniele Tibullo Giuseppe Alberto Palumbo Polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF) are rare hematological conditions...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2332: Trajectories of Short Physical Performance Battery Are Strongly Associated with Future Major Mobility Disability: Results from the LIFE Study Journal of Clinical Medicine doi: 10.3390/jcm9082332 Authors: Joshua D. Brown Wei-Hsuan Lo-Ciganic Hui Shao Marco Pahor Todd M. Manini Short Physical Performance Battery (SPPB) assessment is a widely used measure of lower extremity function, strength, and balance. In the Lifestyles Interventions and Independence...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2333: Selecting Appropriate Sarcopenia Screening Methods for Asian Populations Journal of Clinical Medicine doi: 10.3390/jcm9082333 Authors: Lin Lu Chen Lin Cheung Chan We aimed to determine the most appropriate sarcopenia screening method for Asian populations. We retrospectively studied the physiological differences between the sexes in healthy individuals and prospectively compared using skeletal muscle mass versus handgrip strength (HS) to...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2331: Suprascapular Neuropathy around the Shoulder: A Current Concept Review Journal of Clinical Medicine doi: 10.3390/jcm9082331 Authors: Federico Bozzi Sergi Alabau-Rodriguez Sergi Barrera-Ochoa Atesch Ateschrang Anna J. Schreiner Juan Carlos Monllau Simone Perelli Suprascapular neuropathy is an uncommon but increasingly recognized cause of shoulder pain and dysfunction due to nerve entrapment. The aim of this review is to summarize some important...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2330: The Multidimensional Daily Diary of Fatigue-Fibromyalgia-17 Items (MDF-Fibro-17): Evidence from Validity, Reliability and Transcultural Invariance Between Portugal and Brazil Journal of Clinical Medicine doi: 10.3390/jcm9082330 Authors: Álvarez Albuquerque Neiva Cid Monteiro Rodrigues Teixeira The Multidimensional Daily Diary of Fatigue-Fibromyalgia-17 (MDF-fibro-17) is an instrument that measures the different components of fibromyalgia-related...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2336: Receptor-Associated Prorenin System in the Trabecular Meshwork of Patients with Primary Open-Angle Glaucoma and Neovascular Glaucoma Journal of Clinical Medicine doi: 10.3390/jcm9082336 Authors: Erdal Tan Ishizuka Atsuhiro Kanda Yasuhiro Shinmei Takeshi Ohguchi Yoshiaki Tagawa Keitaro Hase Taku Yamamoto Kousuke Noda Shinki Chin Susumu Ishida The receptor-associated prorenin system (RAPS) is associated with several pathologic conditions,...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2329: Non-Pharmacological Interventions towards Preventing the Triad Osteoporosis-Falls Risk-Hip Fracture, in Population Older than 65. Scoping Review Journal of Clinical Medicine doi: 10.3390/jcm9082329 Authors: Peraza-Delgado Sánchez-Gómez Gómez-Salgado Romero-Martín Novo-Muñoz Duarte-Clíments Osteoporosis leads to increased risk of falls, and thus an increase in fractures, highlighting here hip fractures, that result in high mortality, functional...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2328: Mastitis While Breastfeeding: Prevention, the Importance of Proper Treatment, and Potential Complications Journal of Clinical Medicine doi: 10.3390/jcm9082328 Authors: Miri Pevzner Arik Dahan Mastitis is an inflammation in the breast, which may involve a bacterial infection. Breast infection during breastfeeding is a common phenomenon that requires immediate and appropriate treatment. Without proper treatment, inflammation may lead to the cessation of breastfeeding....
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2326: Elevated Plasma Vitamin B12 in Patients with Hepatic Glycogen Storage Diseases Journal of Clinical Medicine doi: 10.3390/jcm9082326 Authors: Julia Hinkel Johannes Schmitt Michael Wurm Stefanie Rosenbaum-Fabian Karl Otfried Schwab Donald W. Jacobsen Ute Spiekerkoetter Sergey N. Fedosov Luciana Hannibal Sarah C. Grünert Background: Hepatic glycogen storage diseases (GSDs) are inborn errors of metabolism affecting the synthesis or breakdown...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2327: The Acrosomal Status of Density Purified Spermatozoa Differentiates Men from Couples in IVF and ICSI Treatment and Is Associated with Fecundity Journal of Clinical Medicine doi: 10.3390/jcm9082327 Authors: Pernille Badsberg Norup Dorte L. Egeberg Palme Morten R. Petersen Katharina M. Main Kristian Almstrup The acrosome of the spermatozoa is required for fertilization and in the raw ejaculate the percentage of viable acrosome-intact spermatozoa, the...
Wed Jul 22, 2020 03:00
JCM, Vol. 9, Pages 2324: Etiology, Clinical Presentation and Incidence of Infectious Meningitis and Encephalitis in Polish Children Journal of Clinical Medicine doi: 10.3390/jcm9082324 Authors: Kacper Toczylowski Ewa Bojkiewicz Marta Barszcz Marta Wozinska-Klepadlo Paulina Potocka Artur Sulik Little is known about the causes and the frequency of meningitis and encephalitis in Poland. We did a retrospective single-center cohort study of children under 18 years old hospitalized...
Wed Jul 22, 2020 03:00
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