ABSTRACT COVID‐19 pandemic presents several dermatological manifestations described in the present indexed literature, with around 700 cases reported until May 2020, some described as urticaria or urticarial rashes. Urticaria is constituted by evanescent erythematous‐edematous lesions (wheals and flare), which does not persist in the same site for more than 24‐48 hours and appears in other topographic localization, resolving without residual hyper pigmentation. During the SARS‐CoV‐2 infection, some...
Abstract Introduction The objective of the study was to evaluate efficacy and safety of ixekizumab in psoriasis patients under clinical practice conditions. Material and methods Observational, retrospective, multicentre study that included patients with ixekizumab from March 2017 to March 2019. ≥ 90 % reduction in the Psoriasis Area and Severity Index (PASI 90) and absolute PASI < 2 were the parameters used to assess treatment response. Adverse events (AEs) were collected. Results...
Abstract Basal cell carcinoma (BCC) is the most common skin cancer in humans. Pigmented basal cell carcinoma (pBCC) is a rare variant of BCC. Vismodegib, was the first drug to be approved for the treatment of locally advanced (laBCCs) or metastatic basal cell carcinoma. The aim of this study was to evaluate the efficacy of Vismodegib in patients with pBCCs. We retrospectively analyzed patients receiving Vismodegib as treatment for laBCCs presenting also various pBCCs. After 6 months of treatment...
Abstract Behçet's disease is a disease characterized by chronic inflammatory vasculitis. In the clinical symptoms of Behçet's disease, many immunosuppressive and immunomodulatory drugs are used. The suspicion that drugs used in chronic disease treatments such as Behçet's disease during pandemic will increase the risk of transmission of COVID‐19 disease, and that the disease may progress more lethally in these patients after the infection caused clinicians to worry. As far as we know, there is no...
Abstract Background Urticaria is a disease which progresses with itchy papules and plaques called urtica, obstructive sleep apnea syndrome (OSAS) is defined as daytime sleepiness and obstructive apnea and hypopnea attacks during sleep. In this study, we aimed to investigate the relationship between urticaria and OSAS. Materyel and methods Thirty one patients with chronic idiopathic urticaria were included in the study. . Body mass indexes (BMI) were calculated and polysomnography findings...
Abstract Psoriasis patients experience negative attitudes and behaviors exhibited by people who have insufficient knowledge about psoriasis. In this study, the knowledge level of the society about psoriasis; people's attitudes toward such patients were investigated. A questionnaire that investigates the knowledge, attitudes and behaviors related to psoriasis according to age, gender and education levels was applied to the participants. About a quarter of participants in the study did not have any...
Abstract Background The Dangguikushen (DGKS) pill is a proprietary traditional Chinese medicine that has shown superior efficacy in the treatment of acne vulgaris for many years. Methods A network pharmacology‐based analysis was performed to explore the potential anti‐acne compounds, core therapeutic targets, and the main pathways, involved in the DGKS pill bioactivity. The matching results between the predicted targets of the DGKS pill and the well‐known targets of acne vulgaris were collected,...
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