Τετάρτη 22 Ιουλίου 2020


Unforeseen N2 Disease after Negative Endosonography Findings with or without Confirmatory Mediastinoscopy in Resectable Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis.
Related Articles Unforeseen N2 Disease after Negative Endosonography Findings with or without Confirmatory Mediastinoscopy in Resectable Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis. J Thorac Oncol. 2019 06;14(6):979-992 Authors: Bousema JE, van Dorp M, Noyez VJJM, Dijkgraaf MGW, Annema JT, van den Broek FJC Abstract INTRODUCTION: Confirmatory mediastinoscopy after negative endosonography findings is advised by the guidelines...
Subgroups in Laryngeal Carcinoma
Wed Jul 22, 2020 20:39
A Systematic Review of Trauma Crew Resource Management Training: What Can the United States and the United Kingdom Learn From Each Other?
Publication date: Available online 21 July 2020Source: Journal of Surgical EducationAuthor(s): James Ashcroft, Aimee Wilkinson, Mansoor Khan
Journal of Surgical Education
Wed Jul 22, 2020 20:36
Eyes for Ears—A Medical Education Podcast Feasibility Study
Publication date: Available online 21 July 2020Source: Journal of Surgical EducationAuthor(s): Benjamin Young, Andrew Pouw, Amanda Redfern, Fei Cai, Jessica Chow
Journal of Surgical Education
Wed Jul 22, 2020 20:36
A Template for Curriculum Development to Teach Complex Surgical or Endoscopic Techniques With Logistical Challenges
Publication date: Available online 21 July 2020Source: Journal of Surgical EducationAuthor(s): Karen J Dickinson, Brian J Dunkin, Barbara L Bass, Aman B Ali, J. Joseph Nguyen-Lee, Stephanie Zajac
Journal of Surgical Education
Wed Jul 22, 2020 20:36
Video Commentary: Rapid-Fire Assessment of Surgical Cognitive Skills
Publication date: Available online 21 July 2020Source: Journal of Surgical EducationAuthor(s): Mohamed S. Baloul, Vicky J.-H. Yeh, Fareeda Mukhtar, Dhanya Ramachandran, David R. Farley, Mariela Rivera
Journal of Surgical Education
Wed Jul 22, 2020 20:36
Surgical Residents in the Battle Against COVID-19
Publication date: Available online 21 July 2020Source: Journal of Surgical EducationAuthor(s): Oday Obaid, Jason Zimmermann, Guillermo Ares
Journal of Surgical Education
Wed Jul 22, 2020 20:36
Building Rapport and Earning the Surgical Patient's Trust in the Era of Social Distancing: Teaching Patient-Centered Communication During Video Conference Encounters to Medical Students
Publication date: Available online 21 July 2020Source: Journal of Surgical EducationAuthor(s): Anna B. Newcomb, Margaret Duval, Sharon L Bachman, Denise Mohess, Jonathan Dort, Muneera R. Kapadia
Journal of Surgical Education
Wed Jul 22, 2020 20:36
Cross-Sectional Analysis of Global Surgery Opportunities Among General Surgery Residency Programs
Publication date: Available online 21 July 2020Source: Journal of Surgical EducationAuthor(s): Peter J. Abraham, Mackenzie N. Abraham, Britney L. Corey, Brenessa Lindeman, Herbert Chen
Journal of Surgical Education
Wed Jul 22, 2020 20:36
Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres
Presented here is a protocol to discover the overexpressed driver genes maintaining the established cancer stem-like cells derived from colorectal HT29 cells. RNAseq with available bioinformatics was performed to investigate and screen gene expression networks for elucidating a potential mechanism involved in the survival of targeted tumor cells.
JoVE: Journal of Visualized Experiments
Wed Jul 22, 2020 20:24
Universal Screening for Prevention of Reading, Writing, and Math Disabilities in Spanish
This work presents a protocol to administrate Spanish Curriculum-Based Measures for the early detection of reading, math, and writing difficulties. These tools could help practitioners and applied researchers working in the context of the Response to Intervention model.
JoVE: Journal of Visualized Experiments
Sat Jul 18, 2020 21:00
Comparative Analysis of Lower Limb Kinematics between the Initial and Terminal Phase of 5km Treadmill Running
This study investigated the biomechanical characteristics of the lower extremity kinematic variables between the initial and terminal phase of 5 km treadmill running. The lower-limb kinematic data of 10 runners were collected using a three-dimensional motion capture system on a treadmill at the initial phase (0.5 km) and the terminal phase (5 km), respectively.
JoVE: Journal of Visualized Experiments
Fri Jul 17, 2020 22:00
Cercosporin-Photocatalyzed [4+1]- and [4+2]-Annulations of Azoalkenes Under Mild Conditions
New routes for the synthesis of nitrogen-containing heterocycles utilizing cercosporin as a metal-free photocatalyst were developed.
JoVE: Journal of Visualized Experiments
Fri Jul 17, 2020 21:00
Substructure Analyzer: A User-Friendly Workflow for Rapid Exploration and Accurate Analysis of Cellular Bodies in Fluorescence Microscopy Images
We present a freely available workflow built for rapid exploration and accurate analysis of cellular bodies in specific cell compartments in fluorescence microscopy images. This user-friendly workflow is designed on the open-source software Icy and also uses ImageJ functionalities. The pipeline is affordable without knowledge in image analysis.
JoVE: Journal of Visualized Experiments
Wed Jul 15, 2020 22:00
RNA Blot Analysis for the Detection and Quantification of Plant MicroRNAs
This method demonstrates use of the northern hybridization technique to detect miRNAs from total RNA extract.
JoVE: Journal of Visualized Experiments
Sat Jul 11, 2020 22:00
An Improved Protocol to Purify and Directly Mono-Biotinylate Recombinant BDNF in a Tube for Cellular Trafficking Studies in Neurons
Recombinant BDNF containing an Avi sequence (BDNFAvi) is produced in HEK293 cells in a cost-effective manner and is purified by affinity chromatography. BDNFavi is then directly mono-biotinylated with the enzyme BirA in a tube. BDNFavi and mono-biotinylated BDNFavi retain their biological activity when compared to commercially available BDNF.
JoVE: Journal of Visualized Experiments
Sat Jul 11, 2020 21:00
Y-27632 Enriches the Yield of Human Melanocytes from Adult Skin Tissues
This paper reports that the addition of Y-27632 to TIVA medium can significantly increase the yield of melanocytes from adult skin tissues.
JoVE: Journal of Visualized Experiments
Wed Jul 08, 2020 21:00
Quantification of Cell-Substrate Adhesion Area and Cell Shape Distributions in MCF7 Cell Monolayers
The article describes quantification of 1) the size and number of focal adhesions and 2) cell shape index and its distribution from confocal images of the confluent monolayers of MCF7 cells.
JoVE: Journal of Visualized Experiments
Wed Jun 24, 2020 21:00
Identification of late asthmatic reactions following specific inhalation challenge
Specific inhalation challenge (SIC) is the reference standard for the diagnosis of occupational asthma. Current guidelines for identifying late asthmatic reactions are not evidence based.ObjectivesTo identify the fall in forced expiratory volume in 1 s (FEV1) required following SIC to exceed the 95% CI for control days, factors which influence this and to show how this can be applied in routine practice using a statistical method based on the pooled SD for FEV1 from three control days.MethodsFifty...
OEM Online First
Wed Jul 22, 2020 18:59
Nuclei detection in hepatocellular carcinoma and dysplastic liver nodules in histopathology images using bootstrap regression.
Related Articles Nuclei detection in hepatocellular carcinoma and dysplastic liver nodules in histopathology images using bootstrap regression. Histol Histopathol. 2020 Jul 21;:18240 Authors: Kalinathan L, Kathavarayan RS, Kanmani M, Dinakaran N Abstract Hepatocellular carcinoma (HCC) is the most common primary malignant neoplasm of the liver representing the fifth most common malignancy worldwide. This tumor is more common in men than women,...
Cellular and Molecular Biology
Wed Jul 22, 2020 18:47
An automated assessment system of limits of detection and quantitation in gradient high-performance liquid chromatography with ultraviolet detection.
Related Articles An automated assessment system of limits of detection and quantitation in gradient high-performance liquid chromatography with ultraviolet detection. J Chromatogr A. 2020 Jun 21;1621:461077 Authors: Kotani A, Hakamata H, Hayashi Y Abstract A previous paper of this series of study put forward a basic model of an automated system for predicting detection limits and showed its application to a simple example of isocratic high-performance...
low levels of ultrav...
Wed Jul 22, 2020 18:40
Evaluation of the disability assessment Longshi scale: A multicenter study
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveWe investigated factors affecting the disability assessment Longshi scale, and differences between the Longshi and Barthel scales, as well as modified Rankin scale (mRS), to determine whether the Longshi scale is superior to the other scales.MethodsThis cross-sectional study included 721 participants with disability. We performed the t-test, analysis of variance, Pearson’s correlation test, and multiple linear regression...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Wed Jul 22, 2020 15:10
Exploring concomitant neuroimaging and genetic alterations in patients with and patients without auditory verbal hallucinations: A pilot study and mini review
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveTo explore concomitant neuroimaging and genetic alterations in patients with schizophrenia with or without auditory verbal hallucinations (AVHs), and to discuss the use of pattern recognition techniques in the development of an objective index that may improve diagnostic accuracy and treatment outcomes for schizophrenia.MethodsThe pilot study included patients with schizophrenia with AVHs (SCH-AVH group) and without...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Wed Jul 22, 2020 13:29
Pretargeted radioimmunoimaging with a biotinylated D-D3 construct and 99mTc-DTPA-biotin: strategies for early diagnosis of small cell lung cancer
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectivePro-gastrin releasing peptide (ProGRP) plays an oncogenic role in small cell lung cancer (SCLC). The anti-ProGRP(31-98) monoclonal antibody D-D3 can selectively accumulate in SCLC xenografts in nude mice. This study evaluated the effectiveness of a new pretargeting procedure for the early diagnosis of SCLC.MethodsD-D3 was radiolabeled with technetium-99m (99mTc) using a three-step pretargeting method. Mice with SCLC...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 15:33
Improved cardiovascular autonomic function and decreased protein-bound uremic toxins in patients with end-stage renal disease after peritoneal dialysis
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveCardiovascular autonomic neuropathy is highly prevalent in patients with end-stage renal disease (ESRD), and it has a high fatality rate. This study aimed to determine whether peritoneal dialysis (PD) improves cardiovascular autonomic function (CAF) and decreases protein-bound uremic toxin (indoxyl sulfate [IS], p-cresyl sulfate [PCS]) levels.MethodsIS and PCS levels, and parameters of CAF (heart rate response to deep...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 15:33
Inverted U-shaped relationship between body mass index and multivessel lesions in Chinese patients with myocardial infarction: a cross-sectional study
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveTo investigate the association of body mass index (BMI) with multivessel coronary artery disease in patients with myocardial infarction.MethodsThis study was performed in 1566 patients with myocardial infarction in the Department of Cardiology, Affiliated Hospital of Jining Medical University, China. Independent and dependent variables were BMI measured at baseline and multivessel coronary artery disease, respectively....
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 15:33
Necrotizing fasciitis complicated with multiple organ dysfunction syndrome after breast augmentation with fat from the waist and lower extremities: a case report
Journal of International Medical Research, Volume 48, Issue 7, July 2020. Necrotizing fasciitis (NF) is a rapidly progressing soft tissue infection with a mortality rate as high as 30% to 50%. However, the incidence rate of NF after liposuction is extremely low. In the current case report, we describe a woman with NF who developed multiple organ dysfunction syndrome (MODS) after fat acquisition. The aim of this paper is to summarize the management of these patients. After debridement and drainage,...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 15:33
Adrenal failure and antiphospholipid syndrome
Journal of International Medical Research, Volume 48, Issue 7, July 2020. We herein report two cases of primary adrenal insufficiency (AI) associated with antiphospholipid syndrome (APS). In both patients, the main finding that led to the diagnosis was hyponatraemia. The major difference between the two cases was the time at which AI evolved during the course of APS. In the first patient, AI developed acutely along with other presenting features of APS. In the second patient, the AI was unmasked...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 15:33
Association between small intestinal bacterial overgrowth and beta-cell function of type 2 diabetes
Journal of International Medical Research, Volume 48, Issue 7, July 2020. AimsPrevious studies suggest that small intestinal bacterial overgrowth (SIBO) is associated with type 2 diabetes. However, few studies have evaluated the association between SIBO and beta-cell function in type 2 diabetes. The aim of this study was to evaluate whether beta-cell function was associated with SIBO.Materials and methodsOne hundred four patients with type 2 diabetes were included in this study. Based on the presence...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 14:35
Establishment and assessment of a nomogram for predicting adverse outcomes of preterm preeclampsia
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveThis prospective study was designed to develop and internally validate an accurate prognostic nomogram model with which to predict the adverse outcomes of preterm preeclampsia.MethodsPregnant women with preeclampsia were divided into the adverse outcome group and the no adverse outcome group. The Kaplan–Meier method, univariate Cox regression analysis, and calculation of the concordance index (C-index) were applied...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 14:33
Non-tropical fibrocalculous pancreatic diabetes: case reports and review of recent literature
Journal of International Medical Research, Volume 48, Issue 7, July 2020. BackgroundFibrocalculous pancreatic diabetes (FCPD), an uncommon form of secondary diabetes, is caused by chronic nonalcoholic calcific pancreatitis and primarily occurs in tropical countries.ObjectiveTo present our first-hand experiences in the diagnosis and management of FCPD in two patients from a non-tropical location.Case reportTwo male Chinese patients (29 and 32 years old) presented with poor insulin function, negative...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 14:33
Plasma levels of IL-1β and IL-37 in patients with severe haemophilia
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveHaemophilia A and B are disorders caused by the lack of clotting factors VIII and IX, respectively. Repeated bleeding into the same joint leads to haemophilic arthropathy (HA). Interleukin (IL)-1β is responsible for the pro-inflammatory response and IL-37 is induced by IL-1β stimuli to have an anti-inflammatory response and prevent uncontrolled inflammation and tissue damage. Our objective was to investigate plasma...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 14:32
Prognostic value of dynamic plasma endostatin for the prediction of mortality in acute kidney injury: A prospective cohort study
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveThe aim of the current study was to evaluate the value of plasma endostatin for predicting 30-day mortality of patients with acute kidney injury (AKI).MethodsPatients who underwent non-cardiac major surgery and developed AKI in the first 48 hours after admission to the intensive care unit were consecutively included. Concentrations of plasma neutrophil gelatinase-associated lipocalin (NGAL), cystatin C (Cys C), and...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 14:31
Spontaneous hemopneumothorax after laparoscopy: a case report and literature review
Journal of International Medical Research, Volume 48, Issue 7, July 2020. BackgroundSpontaneous hemopneumothorax (SHP) is defined as the accumulation of >400 mL of blood in the pleural cavity in association with spontaneous pneumothorax. This rare clinical disorder may be life-threatening.Case presentationA 71-year-old woman presented with a 1-month history of recurrent bloody stool, and electronic colonoscopy suggested a rectal mass. Laparoscopic radical resection of rectal cancer was performed....
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 13:49
Assessment of two prophylactic fluid strategies in aneurysmal subarachnoid hemorrhage: A randomized trial
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveTo compare the effect of two prophylactic euvolemic fluid strategy regimens on the incidence of cerebral vasospasm and clinical outcomes in patients with aneurysmal subarachnoid hemorrhage (SAH).MethodsNinety-six patients with a basal intravenous intake of 15 mL/kg/day of Ringer’s lactate solution were included, and an additional 15 to 50 mL/kg/day Ringer’s lactate (RL-group) or hydroxyethyl starch 130/0.4 solution...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 11:10
Branchial cleft fistula to branchio-oto-renal syndrome: A case report and literature review
Journal of International Medical Research, Volume 48, Issue 7, July 2020. Branchial cleft abnormality is a common congenital neck malformation in children, which is caused by the abnormal development of the gill sac or gill groove. It is mainly manifested as a cyst in the sinus tract and fistula in the neck, as well as branchio-oto-renal syndrome (BORS). As a rare autosomal dominant genetic disease, the typical manifestations of BORS are hearing loss, abnormal branchial cleft development and renal...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 10:31
Ganglioside GM2: a potential biomarker for cholangiocarcinoma
Journal of International Medical Research, Volume 48, Issue 7, July 2020. ObjectiveTo investigate the expression of glycosphingolipids in serum and tissue from patients with cholangiocarcinoma compared with healthy controls.MethodsNanospray ionization-linear ion trap mass spectrometry (NSI-MSn) was used to demonstrate the comparative structural glycomics of glycosphingolipids in serum from patients with cholangiocarcinoma (n=15), compared with healthy controls (n = 15). GM2 expression in cholangiocarcinoma...
SAGE Publications Ltd: Journal of International Medical Research: Table of Contents
Tue Jul 21, 2020 07:50
Molecular Dynamics in Esophageal Adenocarcinoma: Who's in Control?
Related Articles Molecular Dynamics in Esophageal Adenocarcinoma: Who's in Control? Curr Cancer Drug Targets. 2020 Jul 19;: Authors: Dang T, Chai J Abstract Esophageal adenocarcinoma (EAC) is one of the fastest-growing cancers in the world. It occurs primarily due to the chronic gastroesophageal reflux disease (GERD), during which the esophageal epithelium is frequently exposed to the acidic fluid coming up from the stomach. This triggers gene...
Current Cancer Drug Targets,http://goo.gl/gS0SK0
Wed Jul 22, 2020 18:20
Tumor-induced Metabolism and T Cells Located in Tumor Environment.
Related Articles Tumor-induced Metabolism and T Cells Located in Tumor Environment. Curr Cancer Drug Targets. 2020 Jul 19;: Authors: Iranparast S, Tayebi S, Ahmadpour F, Yousefi B Abstract Several subtypes of T cells are located in a tumor environment, each of which supplies their energy using different metabolic mechanisms. Since the cancer cells require high levels of glucose, the conditions of food poverty in the tumor environment can cause...
Current Cancer Drug Targets,http://goo.gl/gS0SK0
Wed Jul 22, 2020 18:20
Interest of the Virtual Reality Headset in the Management of Perioperative Stress in Patients Candidates for Total Thyroidectomy
Conditions:   Thyroid Cancer;   ThyroidectomyIntervention:   Behavioral: Use of a virtual reality headsetSponsor:   Centre Francois BaclesseNot yet recruiting
ClinicalTrials
Wed Jul 22, 2020 18:19

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου