Abstract Background It remains unclear how to characterize different subtypes of asthma and chronic obstructive pulmonary disease (COPD). We previously described serum periostin and chitinase‐3‐like protein 1 (YKL‐40) as useful markers for asthma‐COPD overlap (ACO). MicroRNAs (miRNAs) are now recognized as markers for identifying the pathophysiological features in several diseases. To identify circulating miRNAs that could discriminate patients with ACO from patients with asthma or COPD. ...
Sat Jul 25, 2020 18:34
Abstract Background Nickel‐induced allergic contact dermatitis (nACD) remains a major occupational skin disorder, significantly impacting the quality‐of‐life of suffering patients. Complex cellular compositional changes and associated immunological pathways are partly resolved in humans, thus, the impact of nACD on human skin needs to be further elucidated. Methods To decipher involved immunological players and pathways, human skin biopsies were taken at 0, 2, 48 and 96 hours after nickel...
Fri Jul 24, 2020 19:05
Fri Jul 24, 2020 18:44
Publication date: Available online 25 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Anthony Shock, David Humphreys, Falk Nimmerjahn
Sun Jul 26, 2020 17:42
Publication date: Available online 25 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Emma S. Chambers, Arne N. Akbar
Sat Jul 25, 2020 17:26
Publication date: Available online 25 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Gary K. Soffer, Randy Horwitz, Andrew Weil
Sat Jul 25, 2020 17:26
Publication date: Available online 24 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Toshiyuki Yoneyama, Nobuhiro Nakano, Mutsuko Hara, Hiromichi Yamada, Kumi Izawa, Koichiro Uchida, Ayako Kaitani, Tomoaki Ando, Jiro Kitaura, Yoshikazu Ohtsuka, Hideoki Ogawa, Ko Okumura, Toshiaki Shimizu
Fri Jul 24, 2020 14:32
Publication date: Available online 24 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Brian Lipworth, Rory Chan, Chris RuiWen Kuo
Fri Jul 24, 2020 14:32
Publication date: Available online 24 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Jonathan J. Lyons, Jack Chovanec, Michael P. O’Connell, Yihui Liu, Julij Šelb, Roberta Zanotti, Yun Bai, Jiwon Kim, Tom DiMaggio, Lawrence B. Schwartz, Hirsh D. Komarow, Matija Rijavec, Melody C. Carter, Joshua D. Milner, Patrizia Bonadonna, Dean D. Metcalfe, Peter Korošec
Fri Jul 24, 2020 14:32
Publication date: Available online 24 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Akhilesh Jha, Ryan S. Thwaites, Tanushree Tunstall, Onn Min Kon, Robin J. Shattock, Trevor T. Hansel, Peter J.M. Openshaw
Fri Jul 24, 2020 14:32
Publication date: Available online 24 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Peter Howarth, Claus Bachert, Ana Sousa, Robert Chan
Fri Jul 24, 2020 14:32
Publication date: Available online 23 July 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Li Xia, Xiang Wang, Lijuan Liu, Jinrong Fu, Wenfeng Xiao, Qiuyan Liang, Xiao Han, Saihua Huang, Licheng Sun, Yajing Gao, Caiyan Zhang, Lan Yang, Libo Wang, Liling Qian, Yufeng Zhou
Fri Jul 24, 2020 14:32
Human microbiota plays a fundamental role in modulating the immune response. Western environment and lifestyle are envisaged to alter the human microbiota with a new microbiome profile established in Chinese i...
Sat Jul 25, 2020 03:00
The cumulative burden of chronic, ongoing, psychological stress increases health costs in the United States. Globally, psychological stress is considered an important public health threat 1. Stress is an adaptive response to an internal and/or external disruptive stimulus that may be conscious or unconscious and is considered protective for the host. It is the subjective perception of excessive stress that causes its negative biological impact 2. Natural physiological response to a stressor is an...
Sat Jul 25, 2020 03:00
Persistent, or chronic, stress and stress correlates (e.g. maternal and childhood anxiety) in early life have been associated with increased risk for new onset respiratory disorders including episodic wheeze and asthma. These findings are not limited to early life, with major negative stressful events in childhood and adolescence prospectively associated with new active asthma diagnosed in adulthood.1 Additionally, while these findings highlight incidence of new asthma, stressors, both acute and...
Fri Jul 24, 2020 03:00
As many as 8% of children live with food allergy, a condition that substantially burdens the child and their family (1). Although food allergy-related burdens have been described in various ways (2), no previous studies have described the burden of food allergy on all family members. Herein, we consider the family burden, by making use of visual analogue scales (VAS) completed by the mother, for all members of the family. These linear scales permit the measurement of subjective or behavioral phenomena...
Fri Jul 24, 2020 03:00
Coronavirus disease 2019 (COVID-19) can present with a myriad of symptoms.1 Guidelines from China, the United Kingdom and Italy had focused screening efforts on patients with fever and cough, excluding anosmia from similar scrutiny.1 However, screening of individuals with reported anosmia and dysgeusia has been associated with a greater likelihood of a positive COVID-19 result than other indicator of an upper respiratory infection.2-4 The relative predictive value of presenting COVID-19 symptoms...
Fri Jul 24, 2020 03:00
ABSTRACT Background Long‐term trajectories of asthma with fixed airflow obstruction (FAO) may reveal links to inflammatory endotypes. Objective We investigated whether measures of asthma control and airways inflammation and remodeling differed by long‐term FAO status in moderate‐to‐severe asthma. Methods Adults enrolled in the Difficult Asthma Study assessed initially using serial asthma control questionnaire (ACQ), exacerbation history, spirometry, and sputum cytology over 12‐months,...
Fri Jul 24, 2020 11:19
Abstract Purpose of Review Telemedicine is a rapidly growing healthcare sector that can improve access to care for underserved populations and offer flexibility and convenience to patients and clinicians alike. However, uncertainty about insurance coverage and reimbursement policies for telemedicine has historically been a major barrier to adoption, especially among physicians in private practice (the majority of practicing allergists)....
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Fri Jul 24, 2020 16:19
Publication date: Available online 25 July 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Maria Luz Lara-Marquez, Keith W. Kelley
Sun Jul 26, 2020 14:12
Publication date: Available online 24 July 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Katharine J. Foster, Emilio Jauregui, Bobby Tajudeen, Faraz Bishehsari, Mahboobeh Mahdavinia
Sat Jul 25, 2020 18:20
Publication date: Available online 24 July 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Eyal Oren, Fernando D. Martinez
Sat Jul 25, 2020 18:20
Publication date: Available online 24 July 2020Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Roelinde Middelveld, Nina V. Gunnarsson, Staffan Ahlstedt, Jennifer Lisa Penner Protudjer
Sat Jul 25, 2020 18:20
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