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Related Articles Joint Encoding of Auditory Timing and Location in Visual Cortex. J Cogn Neurosci. 2019 07;31(7):1002-1017 Authors: Plass J, Ahn E, Towle VL, Stacey WC, Wasade VS, Tao J, Wu S, Issa NP, Brang D Abstract Co-occurring sounds can facilitate perception of spatially and temporally correspondent visual events. Separate lines of research have identified two putatively distinct neural mechanisms underlying two types of crossmodal facilitations:...
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Cost-function testing methodology for image-based registration of endoscopy to CT images in the head and neck. Phys Med Biol. 2020 Jul 23;: Authors: Shi RB, Mirza S, Martinez D, Douglas C, Cho J, Irish JC, Jaffray DA, Weersink RA Abstract One of the largest geometric uncertainties in designing radiotherapy treatment plans for squamous cell cancers of the head and neck is contouring the gross tumour volume. We have previously described...
NF-κB pathway activation during endothelial-to-mesenchymal transition in a rat model of doxorubicin-induced cardiotoxicity. Biomed Pharmacother. 2020 Jul 20;130:110525 Authors: Xu A, Deng F, Chen Y, Kong Y, Pan L, Liao Q, Rao Z, Xie L, Yao C, Li S, Zeng X, Zhu X, Liu H, Gao N, Xue L, Chen F, Xu G, Wei D, Zhou X, Li Z, Sheng X Abstract Doxorubicin is a commonly used anthracycline chemotherapeutic agent; however, its application is limited...
A predictive survival model for patients with head and neck squamous cell carcinoma treated with immune check point inhibitors. Oral Oncol. 2020 Jul 20;110:104900 Authors: Bonomi M, Bhateja P, Issa M, Klamer B, Pan X, Blakaj A, Karivedu V, Mousa L, Mitchell D, Gamez M, Kang S, Siem N, Old M, Carrau R, Rocco J, Blakaj D Abstract BACKGROUND: ICIs have expanded treatment options for HNSCC. A minority of the patients respond to these expensive...
Molecular margins in head and neck cancer: Current techniques and future directions. Oral Oncol. 2020 Jul 20;110:104893 Authors: Stepan KO, Li MM, Kang SY, Puram SV Abstract Complete tumor extirpation with clear surgical margins remains a central tenet of oncologic head and neck surgery. Rates of locoregional recurrence and survival are both significantly worse when clear margins are unable to be obtained. Current clinical practice relies...
Cancer-associated fibroblast regulation by microRNAs promotes invasion of oral squamous cell carcinoma. Oral Oncol. 2020 Jul 20;110:104909 Authors: Matos LL, Menderico Junior GM, Theodoro TR, Pasini FS, Ishikawa MM, Ribeiro AAB, de Mello ES, Pinhal MADS, Moyses RA, Kulcsar MAV, Dedivitis RA, Cernea CR, Kowalski LP Abstract The objective of the present study was to evaluate the role of microRNA-mediated remodeling of the extracellular matrix...
The effects of selective electrical stimulation of the rat cochlea on hippocampal field potentials. Hear Res. 2020 Jul 08;395:108023 Authors: Hitier M, Zhang YF, Sato G, Besnard S, Zheng Y, Smith PF Abstract The hippocampus is a brain structure well known for its importance to spatial learning and memory. As such it is assumed to use multisensory integration in order to generate mathematical maps of the spatial environment. Auditory inputs...
A novel immunohistochemical scoring system reveals associations of C-terminal MET, ectodomain shedding and loss of E-cadherin with poor prognosis in oral squamous cell carcinoma. Hum Pathol. 2020 Jul 20;: Authors: De Herdt MJ, Koljenović S, van der Steen B, Willems SM, Wieringa MH, Nieboer D, Hardillo JA, Gruver AM, Zeng W, Liu L, Baatenburg de Jong RJ, Looijenga LHJ Abstract Using tissue microarrays it was shown that membranous C-terminal...
Elevated mucus interleukin-17A levels are associated with increased prior sinus surgery for chronic rhinosinusitis. Int Forum Allergy Rhinol. 2020 Jul 23;: Authors: Chapurin N, Li P, Chandra RK, Turner JH, Chowdhury NI Abstract BACKGROUND: Recent advances in molecular biology have enabled the identification of potential inflammatory endotypes of chronic rhinosinusitis (CRS), with prior work suggesting differential short-term surgical outcome...
Financial Transactions from Manufacturers to Otolaryngologists in 2018. Laryngoscope. 2020 Jul 23;: Authors: Ramsey T, Curran K, Ostrowski T, Ruffner R, Leapman NG Abstract OBJECTIVE: To characterize in depth non-research and research payments from industry to otolaryngologists in 2018 with an emphasis on product types. METHODS: Centers for Medicare and Medicaid Services Open Payments program was used for data collection: payment...
Women in Otolaryngology: Experiences of Being Female in the Specialty. Laryngoscope. 2020 Jul 23;: Authors: Lawlor C, Kawai K, Tracy L, Sobin L, Kenna M Abstract OBJECTIVES: A broad survey of women otolaryngologists on the current state of the field, including opportunities for advancement, support of family leave, and prevalence of harassment, has not been performed since 1998. An update on the experiences of female otolaryngologists...
Long non-coding RNA PHACTR2-AS1 promotes tongue squamous cell carcinoma metastasis by regulating Snail. J Biochem. 2020 Jul 23;: Authors: Yuan F, Miao Z, Chen W, Wu F, Wei C, Yong J, Xiao C Abstract Long non-coding RNA is an endogenous non-coding RNA that has currently been proved to be an important player in cancer cell biology. In the present study, we investigated the biological role of PHACTR2-AS1 in tongue squamous cell carcinoma...
Smoking, alcohol consumption, and cancer: A mendelian randomisation study in UK Biobank and international genetic consortia participants. PLoS Med. 2020 Jul;17(7):e1003178 Authors: Larsson SC, Carter P, Kar S, Vithayathil M, Mason AM, Michaëlsson K, Burgess S Abstract BACKGROUND: Smoking is a well-established cause of lung cancer and there is strong evidence that smoking also increases the risk of several other cancers. Alcohol consumption...
Overexpression of ALDH1 and EMT marker profile are linked with unfavorable outcome in head and neck cancer. Med Oral Patol Oral Cir Bucal. 2020 Jul 23;: Authors: Vieira V, Campos LH, Jesus LH, Klabunde C, Gamba TD, Flores IL, Oliveira MG, Rados PV Abstract BACKGROUND: The aim of this research was to assess the expression of aldehyde dehydrogenase 1 (ALDH1) and epithelial-mesenchymal transition (EMT) markers in head and neck squamous cell...
The pesticides use and the risk for head and neck cancer: A review of case-control studies. Med Oral Patol Oral Cir Bucal. 2020 Jul 23;: Authors: Leonel AC, Bonan RF, Pinto MB, Kowalski LP, Perez DE Abstract BACKGROUND: Tobacco, alcohol consumption, and HPV infection are the most common risk factors for head and neck cancer (HNC). Despite of this, recent evidences are growing on the association between long-term exposure to pesticides...
Leukocyte- and platelet-rich fibrin does not provide any additional benefit for tooth extraction in head and neck cancer patients post-radiotherapy: a randomized clinical trial. Med Oral Patol Oral Cir Bucal. 2020 Jul 23;: Authors: Palma LF, Marcucci M, Remondes CM, Chambrone L Abstract BACKGROUND: One of the most important complications of radiotherapy (RT) for head and neck cancer (HNC) is osteoradionecrosis (ORN) of the jaws, arising...
HINTS Examination in Acute Vestibular Neuritis: Do Not Look Too Hard for the Skew. J Neuroophthalmol. 2020 Jul 21;: Authors: Green KE, Gold DR Abstract BACKGROUND: An ocular tilt reaction (OTR) is a triad of a skew deviation, head tilt, and ocular counter-roll that can be partial or complete. An OTR can occur anywhere along the utriculo-ocular motor pathways from the labyrinth to the interstitial nucleus of Cajal but is almost always central...
Pinna-Imitating Microphone Directionality Improves Sound Localization and Discrimination in Bilateral Cochlear Implant Users. Ear Hear. 2020 Jul 16;: Authors: Fischer T, Schmid C, Kompis M, Mantokoudis G, Caversaccio M, Wimmer W Abstract OBJECTIVES: To compare the sound-source localization, discrimination, and tracking performance of bilateral cochlear implant users with omnidirectional (OMNI) and pinna-imitating (PI) microphone directionality...
The Effect of Increasing Interphase Gap on N1 Latency of the Electrically Evoked Compound Action Potential and the Stimulation Level Offset in Human Cochlear Implant Users. Ear Hear. 2020 Jul 16;: Authors: Skidmore J, He S Abstract OBJECTIVE: This study reports two potential biomarkers of the physiological status of the cochlear nerve (CN) in cochlear implant users. DESIGN: This project represents a complementary analysis on...
Disparities in human papillomavirus (HPV) vaccine initiation and completion based on sexual orientation among women in the United States. Hum Vaccin Immunother. 2020 Jul 23;:1-6 Authors: Adjei Boakye E, Osazuwa-Peters N, López J, Pham VT, Tobo BB, Wan L, Schootman M, McElroy JA Abstract OBJECTIVES: We compared HPV vaccine initiation and completion of heterosexual with lesbian and bisexual (LB) women. METHODS: We aggregated National...
Appearance of cerebellar cyst following microvascular decompression to treat hemifacial spasm: a report of two cases and literature review. J Int Med Res. 2020 Jul;48(7):300060520932118 Authors: Cui Y, Yang ZX, Wang CM, Zhu ZP Abstract Microvascular decompression (MVD) is an effective and safe approach for treating hemifacial spasm (HFS). Postoperative complications may include facial nerve palsy, hearing loss, intracerebral haematoma,...
Related Articles Shared Decision-making in Head and Neck Surgery: A Review. JAMA Otolaryngol Head Neck Surg. 2020 Jul 23;: Authors: Forner D, Noel CW, Shuman AG, Hong P, Corsten M, Rac VE, Pieterse AH, Goldstein D Abstract Importance: Shared decision-making is a partnership between physicians and patients whereby patient values and preferences are incorporated with the best medical evidence. Shared decision-making may reduce decisional...
Related Articles News Flash!-SARS-CoV-2 Isolated From the Middle Ear and Mastoid. JAMA Otolaryngol Head Neck Surg. 2020 Jul 23;: Authors: Kesser BW PMID: 32701130 [PubMed - as supplied by publisher]
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Related Articles Grooved hydroxyapatite scaffold modulates mitochondria homeostasis and thus promotes osteogenesis in bone mesenchymal stromal cells. Mol Med Rep. 2020 Jul 23;: Authors: Li C, Yang L, Ren X, Lin M, Shen D, Li Y, Zhang X, Liu C, Mu Y Abstract Hydroxyapatite scaffolds (HASs) are widely studied as suitable materials for bone replacement scaffolds due to their chemical similarities to organic materials. In our previous study,...
Related Articles An HNSCC syngeneic mouse model for tumor immunology research and preclinical evaluation. Int J Mol Med. 2020 Jul 22;: Authors: Fu Y, Tian G, Li J, Zhang Z, Xu K Abstract The lack of reliable animal models to assess the safety and efficacy of drugs and to explore the underlying molecular mechanisms is one of the most severe impediments in head and neck squamous cell carcinoma (HNSCC) tumor immunology research. The majority...
Related Articles LINC01123 facilitates proliferation, invasion and chemresistance of colon cancer cells. Biosci Rep. 2020 Jul 23;: Authors: Ye S, Sun B, Wu W, Yu C, Tian T, Lian Z, Liang Q, Zhou Y Abstract Colon cancer is one of the major causes of cancer-related death worldwide. Long non-coding RNA (lncRNA) LINC01123 has been suggested to act as an oncogene in non-small cell lung cancer and a prognostic signature in head and neck squamous...
Related Articles Organ-on-chip model shows that ATP release through connexin hemichannels drives spontaneous Ca2+ signaling in non-sensory cells of the greater epithelial ridge in the developing cochlea. Lab Chip. 2020 Jul 23;: Authors: Mazzarda F, D'Elia A, Massari R, De Ninno A, Bertani FR, Businaro L, Ziraldo G, Zorzi V, Nardin C, Peres C, Chiani F, Tettey-Matey A, Raspa M, Scavizzi F, Soluri A, Salvatore AM, Yang J, Mammano F Abstract ...
Related Articles Congenital Heart Diseases Associated With Cleft Lip and Palate and Its Impact on Surgical Treatment Planning of Patients With Cleft Lip and Palate-A Cross-Sectional Study. Cleft Palate Craniofac J. 2020 Jul 23;:1055665620943082 Authors: Rao G, Desai A, Kumar N Abstract OBJECTIVES: The aim of this study is to know the prevalence, type of congenital heart diseases (CHDs), and its association with cleft lip and/or palate and...
Related Articles Submucous Cleft Palate Repair in Patients With 22q11.2 Deletion Syndrome. Cleft Palate Craniofac J. 2020 Jul 23;:1055665620942436 Authors: Fleming J, Morrell N, Zavala H, Chinnadurai S, Roby BB Abstract OBJECTIVE: To determine whether surgical intervention for submucous cleft palate (SMCP) is more common in children with 22q11.2 deletion syndrome (22q DS) compared to children without 22q DS. DESIGN: Retrospective...
Related Articles Ostmann's Fat Pad-Does it Really Matter? Ann Otol Rhinol Laryngol. 2020 Jul 22;:3489420943219 Authors: Biadsee A, Fanadka F, Dagan O, Firas K, Nageris B Abstract OBJECTIVE: To compare the size of Ostmann's fat pad (OFP) between healthy ears and ears with chronic otitis media with cholestatoma (COMwC) using magnetic resonance imaging (MRI). METHODS: Twenty-six patients with unilateral COMwC underwent mastoidectomy....
Related Articles Submental flap: Game changer in oral cancer reconstruction-A study of 1169 cases. J Surg Oncol. 2020 Jul 22;: Authors: Pradhan SA, Kannan R, Tiwari N, Jain S, Khan S, Rodrigues D, Doctor A, Jatale RG, Agrawal K, Shaikh M Abstract BACKGROUND: Free-flap reconstructions (FFRs) are the standard-of-care following resections for oral cancer. This study assessed an alternative, the pedicled submental flap (SF) for its versatility,...
Related Articles Characteristics of Laryngeal Osteosarcoma: A Critical Review. Oncol Ther. 2020 Jun;8(1):33-44 Authors: Mäkitie AA, Devaney KO, Baujat B, Almangush A, Ferlito A Abstract Laryngeal sarcomas constitute an extremely rare entity among head and neck malignancies. Furthermore, most of them are chondrosarcomas, and the osteogenic form remains a true rarity. In general, there is a lack of information on the characteristics of laryngeal...
Related Articles Does Botulinum Toxin Therapy Improve Quality of Life in Patients with Facial Palsy? Aesthetic Plast Surg. 2020 Jul 22;: Authors: Fuzi J, Taylor A, Sideris A, Meller C Abstract OBJECTIVES: To review the current literature for the efficacy of botulinum toxin therapy to improve quality of life in patients with facial palsy. METHODS: A comprehensive systematic literature search was performed of the Medline, EMBase,...
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Related Articles PD-L1 expression in tongue squamous cell carcinoma. Med Mol Morphol. 2020 Jul 22;: Authors: Akisada N, Nishimoto K, Takao S, Gion Y, Marunaka H, Tachibana T, Makino T, Miki K, Akagi Y, Tsumura M, Toji T, Yoshino T, Nishizaki K, Orita Y, Sato Y Abstract PURPOSE: Immune checkpoint proteins programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1) are important therapeutic targets for head and neck cancer....
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