Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c05031
Fri Jul 17, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c06269
Fri Jul 17, 2020 07:00
Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b13768
Fri Jul 17, 2020 07:00
Facial Plast SurgDOI: 10.1055/s-0040-1713794Difficulty in nasal ventilation is one of the most frequently occurring problems in otorhinolaryngology and its correct diagnosis is the key step to solve it. The dysfunctions in the valve area are a frequent cause of chronic nasal obstruction, though commonly ignored. The objective of the study is to analyze the clinical and functional outcomes in a group of patients with septal deviations and valve compromise treated with spreader graft with endonasal...
Mon Jul 20, 2020 02:00
Facial Plast SurgDOI: 10.1055/s-0040-1713793Clostridium botulinum toxin (BT) must be administered intramuscularly with a syringe, but dead space in the syringe–needle complex may cause product waste and result in cost implications for the patient and provider. Syringe dead space is the volume of residual fluid that remains within the syringe after the plunger is fully depressed during medication injection. We calculated the average volume of remaining product in a syringe–needle complex and cost...
Mon Jul 20, 2020 02:00
Abstract Fibrous tissue and/or new bone are often found surrounding a cochlear implant in the cochlear scalae. This new intrascalar tissue could potentially limit cochlear implant function by increasing impedance and altering signaling pathways between the implant and the auditory nerve. In this study, we investigated the relationship between intrascalar tissue and 5 measures of implant function in guinea pigs. Variation in both spiral ganglion neuron (SGN) survival and intrascalar...
Mon Jul 20, 2020 03:00
Ovarian hyperstimulation syndrome is normally induced by ovarian stimulation drugs. Severe cases of ovarian hyperstimulation syndrome involve complications such as renal failure and thrombosis. Evidence has re...
Mon Jul 20, 2020 03:00
Fetal bladder rupture causing urinary ascites is uncommon. It is generally related to invasive fetal medicine procedures or obstructive disorders such as in posterior urethral valves in male fetuses. An except...
Sun Jul 19, 2020 03:00
The purpose of this study was to assess the palatal suture opening and the pterygopalatine suture disarticulation pattern in the tomographic axial plane after treatment with midfacial skeletal expander (MSE).
Mon Jul 20, 2020 03:00
Hyperemesis gravidarum (HG) is a severe subtype of nausea and vomiting in pregnancy (NVP) that typically affects women in their first trimester of pregnancy. Because HG is a diagnosis of exclusion, a thorough work-up ruling out organic causes must be performed. Herein, we describe a case of a pregnant woman with HG who presented with intractable pain mimicking appendicitis. While her clinical picture and ultrasound findings were only mildly consistent with appendicitis, the only therapy that provided...
Mon Jul 20, 2020 13:05
Abstract Malignant melanoma of nose and paranasal sinus is a rare and devastating disease. The incidence of intranasal malignant melanomas varies from 0.6 to 3.8%. Extensive local invasion, tumor recurrence, distant metastasis accounts for the poor prognosis with advanced stage having mean survival time of 3.5 years. Here we report 2 cases of malignant melanoma of the left nasal cavity with extensive local invasion to paranasal sinuses and destroying medial orbital wall in both...
Mon Jul 20, 2020 03:00
Abstract Cadaveric dissections helps aspiring ear surgeon to learn anatomy of temporal bone so as to avoid injury to the many vital structures. Objectives are to study the course of facial nerve and its variation in 50 cases of temporal bone dissection. To study the various parameter of the tympanomastoid segments of facial nerve, its relation with the important middle ear structures and their variations. To study the incidence of anatomical variations such as dehiscence of bony...
Mon Jul 20, 2020 03:00
Abstract Study aims to assess the postoperative ostium shrinkage pattern and also attempted to evaluate various ostium parameters and their impact on surgical outcome by using DOS scoring system. Prospective study comprising 44 patients of NLD obstruction with 52 procedures performed during October 2016 to November 2018. Various dimensions of bony neo-ostium were recorded intraoperatively and during 1st, 3rd and 6th month follow up. Degree of ostium shrinkage and its correlation...
Mon Jul 20, 2020 03:00
Abstract Tracheostomy is the creation of a stoma at the surface of skin, which leads into trachea. In the critically ill patients, it is one of the most frequently done procedure especially in intensive care unit (ICU) for those requiring prolonged mechanical ventilation. About 24% of all patients in ICU need tracheostomy (Esteban et al. in Am J Respir Crit Care Med 161:1450–1458, 2000). Historically it had a high complication rate and so many authors suggested that it should...
Mon Jul 20, 2020 03:00
Abstract Laryngocele is very uncommon and no consensus regarding its surgical management is yet established. While traditional external approach is still being recommended some suggest a better microlaryngoscopic management assisted by CO2 laser that has gained popularity. Recurrence is better known with conservative surgery but this paper presents a modified single stage endolaryngeal technique for combined laryngoceles to overcome the same. The salient features are (1) A comparatively...
Mon Jul 20, 2020 03:00
J Neurol Surg Rep 2020; 81: e39-e41DOI: 10.1055/s-0040-1709714Cavernous angiomas are congenital vascular malformations that affect the central nervous system. Reports implicated radiation therapy as a triggering factor for the formation of cavernomas but not in relation with head and neck radiation therapy. Radiation-induced cavernomas (RIC) should be considered in the differential diagnosis of focal neurological symptoms in any patient who has received previous cranial-spinal or head and neck radiotherapy.[...]Georg...
Sun Jul 19, 2020 02:00
Background. Preservation of sleep quality is a modifiable and treatable factor, which may enhance the patient’s adherence to other supportive and palliative care procedures. The outcome of sleep disturbances in lung cancer patients before and after treatment aren’t reported. The aim of this study was to investigate changes in sleep quality before and after chemotherapy in locally advanced or metastatic NSCLC patients. Methods. It was a prospective study including 64 patients with stage III or IV...
Mon Jul 20, 2020 18:20
An increasing number of chronic pain patients presenting for surgery are chronic opioid users. Pain management in the postoperative period can be challenging in this population due to the development of tolerance, physical dependence, and hyperalgesia in long-term opioid users. It is common for postoperative pain to be undertreated in these patients, leading to an overall increase in length of hospital stays, health care costs, and decreased patient satisfaction. Identifying opioid-tolerant patients...
Mon Jul 20, 2020 03:00
Pain is one of the leading reasons that brings patients into health care facilities; yet, it often is left undertreated. The biopsychosocial model of pain, which recognizes that pain is multidimensional, explains the complexities that affect the pain experience and response to treatment. Inclusion of behavioral and psychological factors in medical and surgical evaluations can facilitate an optimal outcome. When pain no longer is acute but becomes chronic, access to psychotherapeutic interventions...
Mon Jul 20, 2020 03:00
Otolaryngologic surgeries present challenges to ensuring postoperative pain control owing to their location and nature that may require patients to be NPO for long periods of time, making enteral medication administration difficult or impossible. There are several alternative administration routes to bypass the gastrointestinal tract, including intravenous, transdermal, subcutaneous, and rectal. Options exist for opioid administration in the perioperative setting, including intravenous boluses, patient...
Mon Jul 20, 2020 03:00
The diagnosis “sinus headache” has been reclassified as “headache attributed to disorder of the nose or paranasal sinuses” by the International Headache Society, but the term is still commonly used by patients and primary care doctors alike. Rhinologic symptoms and headache disorders are common, and they may coexist without a causative relationship. Patients may undergo unnecessary medical interventions because of inadequate understanding of the classifications and management of various headache...
Mon Jul 20, 2020 03:00
Otolaryngology has historically lagged behind other specialties with respect to diversity, equity and inclusion (DEI) and remains one of the least diverse specialties as it relates to gender, race and ethnicity. Strategies aimed at increasing DEI include programs designed to provide mentorship, coaching, and sponsorship. Pipeline efforts, inclusivity on committees, bi-directional communication, and equal pay are additional DEI efforts that have been successful in recruiting and retaining those under-represented...
Mon Jul 20, 2020 03:00
Effective training is crucial for medical students if they are to become competent and successful clinicians. Much of this training is performed in person, where medical students will first observe medical procedures and then perform them under supervision. However, the COVID-19 pandemic has disrupted this training architecture, making it more difficult for students to access on-site training at medical facilities. However, having enough fully trained clinicians to respond to the pandemic...
Mon Jul 20, 2020 23:58
Vitls Inc., a company out of Houston, Texas, won FDA clearance for its Vitls Platform, a combination of a vitals monitoring patch, cloud storage, and an app that lets clinicians monitor multiple patients wearing such a patch at once. The patch, which is called Tégo, keeps track of a patient’s heart and respiration rates, heart rate variability, body temperature, and blood oxygenation (SpO2). It’s a wireless, flexible, disposable device with a battery lifetime of about six...
Mon Jul 20, 2020 19:13
UV-Concepts, an Englewood, Colorado firm, is unveiling a new product that uses ultraviolet light to disinfect all kinds of portable medical equipment. The UV-C Enclosure (UVE) is a large reflective chamber inside of which anything from wheelchairs to mobile nurse computer stations can be disinfected within about a minute. The UVE relies on fluorescent tubes that emit light with a strong peak at a 254 nanometer wavelength, which is known to deactivate viruses and bacteria at...
Mon Jul 20, 2020 18:09
A chance mutation that led to spinal defects in a zebrafish has opened a little window into our own fishy past. The single-letter mutation showed that both the ancient and modern recipes for spine development are still to be found in the fish genome.
Mon Jul 20, 2020 21:59
Scientists and historians have pieced together the genomes of old viruses that were used as vaccination strains during and after the American Civil War ultimately leading to the eradication of smallpox.
Mon Jul 20, 2020 16:32
Parkinson's disease (PD) is a neurodegenerative disorder that impacts motor and nonmotor systems, and consequently influences voice. In later stages of the disease, people with PD develop salient hypokinetic dysarthria. However, it is unclear how extensive the voice impairment is in the nonadvanced stages of PD. Therefore, the aim of the current research was to investigate the auditory-perceptual characteristics of voice in people with Parkinson's disease (PWPD) in nonadvanced stages.
Mon Jul 20, 2020 03:00
Adenotonsillectomy is one of the most common pediatric surgical procedures. Postoperative voice changes are a very common concern among patient's parents. Therefore, the aim of this study is to analyze acoustic voice parameters after adenotonsillectomy, tonsillectomy, and adenoidectomy in pediatric patients in a tertiary referral academic center.
Mon Jul 20, 2020 03:00
Mucosal Immunology, Published online: 20 July 2020; doi:10.1038/s41385-020-0325-3A disintegrin and metalloproteinase domain-15 deficiency leads to exaggerated cigarette smoke-induced chronic obstructive pulmonary disease (COPD)-like disease in mice
Mon Jul 20, 2020 03:00
Mon Jul 20, 2020 03:00
AbstractThis is an extremely rare presentation of multiple appendicoliths in one appendix. Multiple appendicoliths as well as appendicoliths larger than 5 mm have been implicated in severe appendicitis as well as perforation and gangrene of the appendix. There is no known correlation with appendicular malignancy. The controversy arises in the surgical management of asymptomatic patients. There is emerging evidence that justifies an elective appendicectomy in asymptomatic patients.
Mon Jul 20, 2020 03:00
AbstractGastric outlet obstruction encompasses a broad spectrum of conditions characterized by complete or incomplete obstruction of the distal stomach, which interrupts gastric emptying and prevents the passage of gastric contents beyond the proximal duodenum. Idiopathic hypertrophic pyloric stenosis is the most common cause with an incidence of 1.5–3 per 1000 live births. However, it is excluded; other causes in children such as peptic ulcer disease are relatively rare. We report a case of an acquired...
Mon Jul 20, 2020 03:00
José Ramos VivasSe suele decir que la nuestra es una sociedad que no mira de frente a la muerte, que trata de ocultarla. Ciertamente no sería ni higiénico ni agradable ver cadáveres amontonados en las calles, ni plato de buen gusto asistir a la agonía y a los últimos estertores en el lecho de muerte de nuestros familiares y allegados. Pero hemos de admitir que el culto a la juventud, la salud, la belleza, el bienestar etc, sesgan nuestra percepción de la vida.Los grandes hospitales en los que tantas...
Mon Jul 20, 2020 22:33
Zusammenfassung Tracheostomaventile haben sich zur Stimmrehabilitation bei tracheotomierten und laryngektomierten Patienten bewährt. Dennoch wurde in den letzten Jahren eine Reihe von schwerwiegenden Zwischenfällen mit Tracheostomaventilen publiziert. Die Analyse der Zwischenfälle sowie der auf dem Markt verfügbaren Tracheostomaventile, ihrer Funktionen und Einschränkungen ermöglicht es, typische Risiken abzuleiten. Die meisten gemeldeten Zwischenfälle verursachten das versehentliche...
Mon Jul 20, 2020 03:00
Single-chain variable fragments (scFvs) have gained increased attention among researchers in both academic and industrial fields owing to simple production in E. coli. The E. coli periplasm has been the site of c...
Mon Jul 20, 2020 03:00
Abstract Purpose This evaluation describes efforts taken by MIECHV administrators and staff during the pandemic using data collected from 60 MIECHV staff surveys and nine statewide weekly focus groups. Description The Florida Maternal, Infant and Early Childhood Home Visiting (MIECHV) Initiative funds perinatal home visiting for pregnant women and...
Mon Jul 20, 2020 03:00
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