Antibiotics, Vol. 9, Pages 424: Non-Tuberculous Mycobacteria in Respiratory Specimens of Patients with Obstructive Lung Diseases—Colonization or Disease? Antibiotics doi: 10.3390/antibiotics9070424 Authors: Monika Szturmowicz Karina Oniszh Dorota Wyrostkiewicz Piotr Radwan-Rohrenschef Dorota Filipczak Anna Zabost Non-tuberculous mycobacteria (NTM) are increasingly a cause of human respiratory tract colonization and mycobacterial lung disease (NTM-LD), especially in patients...
Mon Jul 20, 2020 03:00
Antibodies, Vol. 9, Pages 34: Monoclonal Antibodies in Cancer Therapy Antibodies doi: 10.3390/antib9030034 Authors: David Zahavi Louis Weiner Monoclonal antibody-based immunotherapy is now considered to be a main component of cancer therapy, alongside surgery, radiation, and chemotherapy. Monoclonal antibodies possess a diverse set of clinically relevant mechanisms of action. In addition, antibodies can directly target tumor cells while simultaneously promoting the induction of long-lasting...
Mon Jul 20, 2020 03:00
Antioxidants, Vol. 9, Pages 638: Can Meat and Meat-Products Induce Oxidative Stress? Antioxidants doi: 10.3390/antiox9070638 Authors: Macho-González Garcimartín López-Oliva Bastida Benedí Ros Nieto Sánchez-Muniz High meat and meat-products consumption has been related to degenerative diseases. In addition to their saturated fatty acids and cholesterol contents, oxidation products generated during their production, storage, digestion, and metabolization have...
Mon Jul 20, 2020 03:00
Arts, Vol. 9, Pages 82: Playful Machines and Heritage: How to Prepare Future Cultural Histories? Arts doi: 10.3390/arts9030082 Authors: Mirosław Filiciak How are we to tackle digital heritage? The fact that its code can be copied, combined with a strong reliance on user interaction, is a distinguishing characteristic of digital art, one which also complicates framing it with the traditional categories of art history. Therefore, in my search for the new ways to preserve heritage, appropriate...
Mon Jul 20, 2020 03:00
Atmosphere, Vol. 11, Pages 766: Analysis of Pollution Characteristics and Influencing Factors of Main Pollutants in the Atmosphere of Shenyang City Atmosphere doi: 10.3390/atmos11070766 Authors: Tian Fang Qiu Wang Air pollution is one of the most concerning environmental problems in cities. Hourly data on pollutant concentrations from 11 automatic atmospheric monitoring stations and meteorological data in Shenyang from 2017 to 2019 were used to analyze the spatio-temporal...
Mon Jul 20, 2020 03:00
Atmosphere, Vol. 11, Pages 767: Climate Change, Climatic Extremes, and Human Societies in the Past Atmosphere doi: 10.3390/atmos11070767 Authors: Harry F. Lee More people appreciate the importance of global sustainability [...]
Mon Jul 20, 2020 03:00
Atmosphere, Vol. 11, Pages 765: Capturing the Variability in Instantaneous Vehicle Emissions Based on Field Test Data Atmosphere doi: 10.3390/atmos11070765 Authors: Zhiqiang Zhai Ran Tu Junshi Xu An Wang Marianne Hatzopoulou Emission models are important tools for traffic emission and air quality estimates. Existing instantaneous emission models employ the steady-state “engine emissions map” to estimate emissions for individual vehicles. However, vehicle...
Mon Jul 20, 2020 03:00
Atmosphere, Vol. 11, Pages 764: Efficacy of Radiant Catalytic Ionization in Reduction of Enterococcus spp., Clostridioides difficile and Staphylococcus aureus in Indoor Air Atmosphere doi: 10.3390/atmos11070764 Authors: Krzysztof Skowron Katarzyna Grudlewska-Buda Sylwia Kożuszko Natalia Wiktorczyk Karolina Jadwiga Skowron Agnieszka Mikucka Zuzanna Bernaciak Eugenia Gospodarek-Komkowska (1) Background: An aerogenic way is one of main rout of spreading microorganisms...
Mon Jul 20, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 118: Is All Dating Violence Equal? Gender and Severity Differences in Predictors of Perpetration Behavioral Sciences doi: 10.3390/bs10070118 Authors: Gabriela Ontiveros Arthur Cantos Po-Yi Chen Ruby Charak K. Daniel O'Leary The present study assesses the extent of perpetration of physical violence in predominately Hispanic high school students in the Rio Grande Valley, Texas. The relationship between adverse childhood experiences, exposure...
Mon Jul 20, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 117: Impulsivity and Empathy in Dating Violence among a Sample of College Females Behavioral Sciences doi: 10.3390/bs10070117 Authors: Arta Dodaj Kristina Sesar Nataša Šimić The predictive factors of violence between married couples or adolescents are well-known. However, less is known about the factors relating to intimate violence among college students. This study examined sociodemographic variables (age, duration of relationship, and relationship...
Mon Jul 20, 2020 03:00
Behavioral Sciences, Vol. 10, Pages 119: Music Listening as Coping Behavior: From Reactive Response to Sense-Making Behavioral Sciences doi: 10.3390/bs10070119 Authors: Mark Reybrouck Piotr Podlipniak David Welch Coping is a survival mechanism of living organisms. It is not merely reactive, but also involves making sense of the environment by rendering sensory information into percepts that have meaning in the context of an organism’s cognitions. Music listening, on the...
Mon Jul 20, 2020 03:00
Bioengineering, Vol. 7, Pages 78: Lactate-Based Model Predictive Control Strategy of Cell Growth for Cell Therapy Applications Bioengineering doi: 10.3390/bioengineering7030078 Authors: Kathleen Van Beylen Ali Youssef Alberto Peña Fernández Toon Lambrechts Ioannis Papantoniou Jean-Marie Aerts Implementing a personalised feeding strategy for each individual batch of a bioprocess could significantly reduce the unnecessary costs of overfeeding the cells. This paper uses lactate...
Mon Jul 20, 2020 03:00
Bioengineering, Vol. 7, Pages 77: An Approach towards a GMP Compliant In-Vitro Expansion of Human Adipose Stem Cells for Autologous Therapies Bioengineering doi: 10.3390/bioengineering7030077 Authors: Valentin Jossen Francesco Muoio Stefano Panella Yves Harder Tiziano Tallone Regine Eibl Human Adipose Tissue Stem Cells (hASCs) are a valuable source of cells for clinical applications (e.g., treatment of acute myocardial infarction and inflammatory diseases), especially...
Mon Jul 20, 2020 03:00
Bioengineering, Vol. 7, Pages 76: Recent Trends in Injury Models to Study Skeletal Muscle Regeneration and Repair Bioengineering doi: 10.3390/bioengineering7030076 Authors: Sydnee T. Sicherer Rashmi S. Venkatarama Jonathan M. Grasman Skeletal muscle injuries that occur from traumatic incidents, such as those caused by car accidents or surgical resections, or from injuries sustained on the battlefield, result in the loss of functionality of the injured muscle. To understand skeletal...
Mon Jul 20, 2020 03:00
Bioengineering, Vol. 7, Pages 75: Human Embryonic-Derived Mesenchymal Progenitor Cells (hES-MP Cells) are Fully Supported in Culture with Human Platelet Lysates Bioengineering doi: 10.3390/bioengineering7030075 Authors: Sandra M. Jonsdottir-Buch Kristbjorg Gunnarsdottir Olafur E. Sigurjonsson Human embryonic stem cell-derived mesenchymal progenitor (hES-MP) cells are mesenchymal-like cells, derived from human embryonic stem cells without the aid of feeder cells. They have been...
Mon Jul 20, 2020 03:00
Biology, Vol. 9, Pages 175: Impairments of Synaptic Plasticity Induction Threshold and Network Oscillatory Activity in the Hippocampus Underlie Memory Deficits in a Non-Transgenic Mouse Model of Amyloidosis Biology doi: 10.3390/biology9070175 Authors: Jennifer Mayordomo-Cava Guillermo Iborra-Lázaro Souhail Djebari Sara Temprano-Carazo Irene Sánchez-Rodríguez Danko Jeremic Agnès Gruart José María Delgado-García Lydia Jiménez-Díaz Juan D. Navarro-López In early...
Mon Jul 20, 2020 03:00
Biology, Vol. 9, Pages 176: Testosterone Decreases Placental Mitochondrial Content and Cellular Bioenergetics Biology doi: 10.3390/biology9070176 Authors: Jay S. Mishra Chellakkan S. Blesson Sathish Kumar Placental mitochondrial dysfunction plays a central role in the pathogenesis of preeclampsia. Since preeclampsia is a hyperandrogenic state, we hypothesized that elevated maternal testosterone levels induce damage to placental mitochondria and decrease bioenergetic profiles. To...
Mon Jul 20, 2020 03:00
Biomedicines, Vol. 8, Pages 228: Novel MRI Techniques Identifying Vascular Leak and Paravascular Flow Reduction in Early Alzheimer Disease Biomedicines doi: 10.3390/biomedicines8070228 Authors: Charles R Joseph With beta amyloid and tau antibody treatment trial failures, avenues directed to other facets of the disease pathophysiology are being explored to treat in the preclinical or early clinical state. Clear evidence of blood–brain barrier (BBB) breakdown occurring early...
Mon Jul 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1080: Analysis of Protein Disorder Predictions in the Light of a Protein Structural Alphabet Biomolecules doi: 10.3390/biom10071080 Authors: Alexandre G. de Brevern Intrinsically-disordered protein (IDP) characterization was an amazing change of paradigm in our classical sequence-structure-function theory. Moreover, IDPs are over-represented in major disease pathways and are now often targeted using small molecules for therapeutic purposes. This has had created...
Mon Jul 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1079: POSCAbilities: The Application of the Prion Organotypic Slice Culture Assay to Neurodegenerative Disease Research Biomolecules doi: 10.3390/biom10071079 Authors: Hailey Pineau Valerie Sim Prion diseases are fatal, transmissible neurodegenerative disorders whose pathogenesis is driven by the misfolding, self-templating and cell-to-cell spread of the prion protein. Other neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s...
Mon Jul 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1078: Coupling Ion Specificity of the Flagellar Stator Proteins MotA1/MotB1 of Paenibacillus sp. TCA20 Biomolecules doi: 10.3390/biom10071078 Authors: Sakura Onoe Myu Yoshida Naoya Terahara Yoshiyuki Sowa The bacterial flagellar motor is a reversible rotary molecular nanomachine, which couples ion flux across the cytoplasmic membrane to torque generation. It comprises a rotor and multiple stator complexes, and each stator complex functions as an...
Mon Jul 20, 2020 03:00
Biomolecules, Vol. 10, Pages 1077: Dual-Functioning Antibacterial Eugenol-Derived Plasticizers for Polylactide Biomolecules doi: 10.3390/biom10071077 Authors: Wenxiang Xuan Karin Odelius Minna Hakkarainen Dual-functioning additives with plasticizing and antibacterial functions were designed by exploiting the natural aromatic compound eugenol and green platform chemical levulinic acid or valeric acid that can be produced from biobased resources. One-pot synthesis methodology was...
Mon Jul 20, 2020 03:00
Biosensors, Vol. 10, Pages 78: Electrochemical DNA Sensor for Sensitive BRCA1 Detection Based on DNA Tetrahedral-Structured Probe and Poly-Adenine Mediated Gold Nanoparticles Biosensors doi: 10.3390/bios10070078 Authors: Dezhi Feng Jing Su Guifang He Yi Xu Chenguang Wang Mengmeng Zheng Qiuling Qian Xianqiang Mi BRCA1 is the biomarker for the early diagnosis of breast cancer. Detection of BRCA1 has great significance for the genetic analysis, early diagnosis and clinical...
Mon Jul 20, 2020 03:00
Brain Sciences, Vol. 10, Pages 468: The Effect of Inquiry-Based Stress Reduction on Teacher Burnout: A Controlled Trial Brain Sciences doi: 10.3390/brainsci10070468 Authors: Lia Schnaider-Levi Ariel B. Ganz Keren Zafrani Zehavit Goldman Inbal Mitnik Benjamin Rolnik Shahar Lev-Ari Burnout is a well-known phenomenon with significant social, biological and economic costs. In particular, teacher burnout is associated with unfavorable mental health outcomes and economic...
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Brain Sciences, Vol. 10, Pages 466: Cerebrospinal Fluid Biomarkers in Parkinson’s Disease: A Critical Overview of the Literature and Meta-Analyses Brain Sciences doi: 10.3390/brainsci10070466 Authors: Takayuki Katayama Jun Sawada Kae Takahashi Osamu Yahara Parkinson’s disease (PD) is a common neurodegenerative disorder; however, well-established biochemical markers have not yet been identified. This review article covers several candidate cerebrospinal fluid (CSF)...
Mon Jul 20, 2020 03:00
Brain Sciences, Vol. 10, Pages 467: Tolerability and Blinding of Transcranial Direct Current Stimulation in People with Parkinson’s Disease: A Critical Review Brain Sciences doi: 10.3390/brainsci10070467 Authors: Craig D. Workman Alexandra C. Fietsam Thorsten Rudroff Transcranial direct current stimulation (tDCS) is accompanied by transient sensations (e.g., tingling, itching, burning), which may affect treatment outcomes or break the blinding of the study protocol. Assessing tolerability...
Mon Jul 20, 2020 03:00
Brain Sciences, Vol. 10, Pages 465: COVID-19: Pain Management in Patients with SARS-CoV-2 Infection—Molecular Mechanisms, Challenges, and Perspectives Brain Sciences doi: 10.3390/brainsci10070465 Authors: Sylwester Drożdżal Jakub Rosik Kacper Lechowicz Filip Machaj Bartosz Szostak Paweł Majewski Iwona Rotter Katarzyna Kotfis Since the end of 2019, the whole world has been struggling with the pandemic of the new Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)....
Mon Jul 20, 2020 03:00
Brain Sciences, Vol. 10, Pages 464: Mouse Tracking to Explore Motor Inhibition Processes in Go/No-Go and Stop Signal Tasks Brain Sciences doi: 10.3390/brainsci10070464 Authors: Viola Benedetti Gioele Gavazzi Fabio Giovannelli Riccardo Bravi Fiorenza Giganti Diego Minciacchi Mario Mascalchi Massimo Cincotta Maria Pia Viggiano Response inhibition relies on both proactive and reactive mechanisms that exert a synergic control on goal-directed actions. It is typically...
Mon Jul 20, 2020 03:00
Cancers, Vol. 12, Pages 1981: High-Throughput Sequencing of Gastric Cancer Patients: Unravelling Genetic Predispositions Towards an Early-Onset Subtype Cancers doi: 10.3390/cancers12071981 Authors: Julita Machlowska Przemysław Kapusta Jacek Baj Folkert H. M. Morsink Paweł Wołkow Ryszard Maciejewski G. Johan A. Offerhaus Robert Sitarz Background: Gastric cancer is the fourth most common cause of cancer-related death. Currently, it is broadly accepted that the molecular...
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Cancers, Vol. 12, Pages 1979: DCE-MRI of Tumor Hypoxia and Hypoxia-Associated Aggressiveness Cancers doi: 10.3390/cancers12071979 Authors: Jon-Vidar Gaustad Anette Hauge Catherine S. Wegner Trude G. Simonsen Kjersti V. Lund Lise Mari K. Hansem Einar K. Rofstad Tumor hypoxia is associated with resistance to treatment, aggressive growth, metastatic dissemination, and poor clinical outcome in many cancer types. The potential of dynamic contrast-enhanced magnetic resonance...
Mon Jul 20, 2020 03:00
Cancers, Vol. 12, Pages 1978: Depletion of Macrophages Improves Therapeutic Response to Gemcitabine in Murine Pancreas Cancer Cancers doi: 10.3390/cancers12071978 Authors: Buchholz Goetze Singh Ammer-Herrmenau Richards Jodrell Buchholz Michl Ellenrieder Hessmann Neesse Background: The tumor microenvironment (TME) is composed of fibro-inflammatory cells and extracellular matrix (ECM) components. However, the exact contribution of the various TME...
Mon Jul 20, 2020 03:00
Cancers, Vol. 12, Pages 1980: Meta-Analysis Reveals Significant Sex Differences in Chronic Lymphocytic Leukemia Progression in the Eµ-TCL1 Transgenic Mouse Model Cancers doi: 10.3390/cancers12071980 Authors: Maximilian Koch Sebastian Reinartz Julia Saggau Gero Knittel Natascha Rosen Oleg Fedorchenko Lisa Thelen Romy Barthel Nina Reinart Tamina Seeger-Nukpezah Hans Christian Reinhardt Michael Hallek Phuong-Hien Nguyen The Eµ-TCL1 transgenic...
Mon Jul 20, 2020 03:00
Cancers, Vol. 12, Pages 1976: The Impact on Survival and Morbidity of Portal–Mesenteric Resection During Pancreaticoduodenectomy for Pancreatic Head Adenocarcinoma: A Systematic Review and Meta-Analysis of Comparative Studies Cancers doi: 10.3390/cancers12071976 Authors: Alessandro Fancellu Niccolò Petrucciani Alberto Porcu Giulia Deiana Valeria Sanna Chiara Ninniri Teresa Perra Valentina Celoria Giuseppe Nigri Background: The literature is conflicting regarding...
Mon Jul 20, 2020 03:00
Cancers, Vol. 12, Pages 1977: Glucose Loading Enhances the Value of 18F-FDG PET/CT for the Characterization and Delineation of Cerebral Gliomas Cancers doi: 10.3390/cancers12071977 Authors: Dongwoo Kim Hae Young Ko Sangwon Lee Yong-ho Lee Sujin Ryu Seon Yoo Kim Jee-in Chung Misu Lee Ju Hyung Moon Jong Hee Chang Mijin Yun This study aimed to assess how to enhance the value of 18F-Fluorodeoxyglucose (FDG) PET/CTs for glioma grading and better delineation of...
Mon Jul 20, 2020 03:00
Cancers, Vol. 12, Pages 1974: Reconstitution of T Cell Subsets Following Allogeneic Hematopoietic Cell Transplantation Cancers doi: 10.3390/cancers12071974 Authors: Linde Dekker Coco de Koning Caroline Lindemans Stefan Nierkens Allogeneic (allo) hematopoietic cell transplantation (HCT) is the only curative treatment option for patients suffering from chemotherapy-refractory or relapsed hematological malignancies. The occurrence of morbidity and mortality after allo-HCT is still...
Mon Jul 20, 2020 03:00
Cancers, Vol. 12, Pages 1973: Characterization of Driver Mutations in Anaplastic Thyroid Carcinoma Identifies RAS and PIK3CA Mutations as Negative Survival Predictors Cancers doi: 10.3390/cancers12071973 Authors: Lai Liu Lin Chen Hang Anaplastic thyroid carcinoma (ATC) is rare but highly aggressive. We investigated the association of selected driver mutations, including BRAF, RAS, PIK3CA, TERT promoter, TP53, POLE, and mismatch repair deficiency (MMR-D) with the clinicopathological...
Mon Jul 20, 2020 03:00
Cancers, Vol. 12, Pages 1972: Inhibition of Methyltransferase DOT1L Sensitizes to Sorafenib Treatment AML Cells Irrespective of MLL-Rearrangements: A Novel Therapeutic Strategy for Pediatric AML Cancers doi: 10.3390/cancers12071972 Authors: Annalisa Lonetti Valentina Indio Maria Antonella Laginestra Giuseppe Tarantino Francesca Chiarini Annalisa Astolfi Salvatore N. Bertuccio Alberto M. Martelli Franco Locatelli Andrea Pession Riccardo Masetti Pediatric...
Mon Jul 20, 2020 03:00
Cancers, Vol. 12, Pages 1975: Treatment of Patients with Advanced Biliary Tract Cancer with Either Oxaliplatin, Gemcitabine, and Capecitabine or Cisplatin and Gemcitabine—A Randomized Phase II Trial Cancers doi: 10.3390/cancers12071975 Authors: Alice Markussen Lars Henrik Jensen Laura Vittrup Diness Finn Ole Larsen This study is an investigator-initiated randomized phase II trial focusing on the treatment of advanced biliary tract cancer with either oxaliplatin 50 mg/m2 and...
Mon Jul 20, 2020 03:00
Cancers, Vol. 12, Pages 1968: Effectiveness and Safety of Nivolumab in Child–Pugh B Patients with Hepatocellular Carcinoma: A Real-World Cohort Study Cancers doi: 10.3390/cancers12071968 Authors: Won-Mook Choi Danbi Lee Ju Hyun Shim Kang Mo Kim Young-Suk Lim Han Chu Lee Changhoon Yoo Sook Ryun Park Min-Hee Ryu Baek-Yeol Ryoo Jonggi Choi Nivolumab has shown durable response and safety in patients with hepatocellular carcinoma (HCC) in previous trials. However,...
Mon Jul 20, 2020 03:00
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