Antibiotics, Vol. 9, Pages 271: Mining the Biosynthetic Potential for Specialized Metabolism of a Streptomyces Soil Community Antibiotics doi: 10.3390/antibiotics9050271 Authors: Matthieu Nicault Abdoul-Razak Tidjani Anthony Gauthier Stéphane Dumarcay Eric Gelhaye Cyril Bontemps Pierre Leblond The diversity and distribution of specialized metabolite gene clusters within a community of bacteria living in the same soil habitat are poorly documented. Here we analyzed the...
Sat May 23, 2020 03:00
Antioxidants, Vol. 9, Pages 452: The Antioxidant Enzyme Methionine Sulfoxide Reductase A (MsrA) Interacts with Jab1/CSN5 and Regulates Its Function Antioxidants doi: 10.3390/antiox9050452 Authors: Beichen Jiang Zachary Adams Shannon Moonah Honglian Shi Julie Maupin-Furlow Jackob Moskovitz Methionine sulfoxide (MetO) is an oxidative posttranslational modification that primarily occurs under oxidative stress conditions, leading to alteration of protein structure and function....
Sun May 24, 2020 03:00
Antioxidants, Vol. 9, Pages 453: Biological Activity of Phenolic Compounds in Extra Virgin Olive Oils through Their Phenolic Profile and Their Combination with Anticancer Drugs Observed in Human Cervical Carcinoma and Colon Adenocarcinoma Cells Antioxidants doi: 10.3390/antiox9050453 Authors: Jelena Torić Anamaria Brozovic Mirela Baus Lončar Cvijeta Jakobušić Brala Ana Karković Marković Đani Benčić Monika Barbarić The roles of phenolics from olive oils as effective...
Sun May 24, 2020 03:00
Antioxidants, Vol. 9, Pages 451: State of the Art of Anthocyanins: Antioxidant Activity, Sources, Bioavailability, and Therapeutic Effect in Human Health Antioxidants doi: 10.3390/antiox9050451 Authors: Tena Martín Asuero The antioxidant activity of anthocyanins in food is well known. Numerous antioxidant assays have been proposed to measure the capacity of anthocyanins to prevent the oxidation process that naturally occurs. Different solvents, temperatures, and pH levels are...
Sat May 23, 2020 03:00
Antioxidants, Vol. 9, Pages 450: Total Oxidant and Antioxidant Capacity of Gingival Crevicular Fluid and Saliva in Patients with Periodontitis: Review and Clinical Study Antioxidants doi: 10.3390/antiox9050450 Authors: Joanna Toczewska Mateusz Maciejczyk Tomasz Konopka Anna Zalewska Periodontitis is inextricably linked to oxidative-reductive (redox) imbalance. However, little is still known about the resultant ability to scavenge oxygen free radicals in saliva and gingival crevicular...
Sat May 23, 2020 03:00
Antioxidants, Vol. 9, Pages 449: Neuroprotective Effects of Euonymus alatus Extract on Scopolamine-Induced Memory Deficits in Mice Antioxidants doi: 10.3390/antiox9050449 Authors: Woo Lim Oh Lee Kim Euonymus alatus is considered to elicit various beneficial effects against cancer, hyperglycemia, menstrual discomfort, diabetic complications, and detoxification. The young leaves of this plant are exploited as food and also utilized for traditional medicine in East Asian...
Fri May 22, 2020 03:00
Antioxidants, Vol. 9, Pages 448: Oxidative Stress and Photodynamic Therapy of Skin Cancers: Mechanisms, Challenges and Promising Developments Antioxidants doi: 10.3390/antiox9050448 Authors: Alessandro Allegra Giovanni Pioggia Alessandro Tonacci Caterina Musolino Sebastiano Gangemi Ultraviolet radiation is one of the most pervasive environmental interactions with humans. Chronic ultraviolet irradiation increases the danger of skin carcinogenesis. Probably, oxidative stress...
Fri May 22, 2020 03:00
Antioxidants, Vol. 9, Pages 447: Chemical Profile and Antioxidant Activity of the Kombucha Beverage Derived from White, Green, Black and Red Tea Antioxidants doi: 10.3390/antiox9050447 Authors: Karolina Jakubczyk Justyna Kałduńska Joanna Kochman Katarzyna Janda Kombucha is a fermented tea beverage prepared as a result of the symbiotic nature of bacterial cultures and yeast, the so-called SCOBY (Symbiotic Cultures of Bacteria and Yeasts). Kombucha is characterised by rich chemical...
Fri May 22, 2020 03:00
Atmosphere, Vol. 11, Pages 545: Quantifying the Economic Cost of Reducing GHG Emissions through Changes in Household Demand: A Linear Multi-Sectoral Approach for European Countries Atmosphere doi: 10.3390/atmos11050545 Authors: Mainar-Causapé. Barrera-Lozano Fuentes-Saguar The mitigation of Greenhouse Gas Emissions can be approached in various ways: from the supply side, by using improvements in technologies and input uses; and from the changes in the demand for products, by...
Sun May 24, 2020 03:00
Atmosphere, Vol. 11, Pages 543: The Climatological Analysis of Typhoon Tracks, Steering Flow, and the Pacific Subtropical High in the Vicinity of Taiwan and the Western North Pacific Atmosphere doi: 10.3390/atmos11050543 Authors: Chih-wen Hung Ming-Fu Shih Te-Yuan Lin Taiwan frequently suffers from typhoon hits in the boreal summer and fall. The location of Taiwan makes it vulnerable to the pathways of typhoons mainly determined by the position of the Pacific subtropical high....
Sat May 23, 2020 03:00
Atmosphere, Vol. 11, Pages 544: Heavy Rainfall and Landslide Event in January 1831 at the Pedregoso Mountains (Cabeza Del Buey, SW Spain) Atmosphere doi: 10.3390/atmos11050544 Authors: Juan Pedro García-Garrido María Cruz Gallego Teodoro Palacios Ricardo M. Trigo José Manuel Vaquero In this work, a landslide event that took place on January 1831 at the Pedregoso Mountains, Cabeza del Buey, SW Spain, is described. This landslide had not been documented to date and was only...
Sat May 23, 2020 03:00
Atmosphere, Vol. 11, Pages 542: Secondary Ice Formation in Idealised Deep Convection—Source of Primary Ice and Impact on Glaciation Atmosphere doi: 10.3390/atmos11050542 Authors: Annette K. Miltenberger Tim Lüttmer Christoph Siewert Secondary ice production via rime-splintering is considered to be an important process for rapid glaciation and high ice crystal numbers observed in mixed-phase convective clouds. An open question is how rime-splintering is triggered in the relatively...
Sat May 23, 2020 03:00
Atmosphere, Vol. 11, Pages 541: Application of Lightning Data Assimilation for the 10 October 2018 Case Study over Sardinia Atmosphere doi: 10.3390/atmos11050541 Authors: Torcasio Federico Puca Vulpiani Prat Dietrich On 10 October 2018 an intense storm, characterized by heavy rainfall, hit the Sardinia island, reaching a peak of 452 mm of rain measured in 24 h. Among others, two particularly intense phases were registered between 3 and 6 UTC (Universal Coordinated...
Fri May 22, 2020 03:00
Atmosphere, Vol. 11, Pages 539: Balancing Waste and Nutrient Flows Between Urban Agglomerations and Rural Ecosystems: Biochar for Improving Crop Growth and Urban Air Quality in The Mediterranean Region Atmosphere doi: 10.3390/atmos11050539 Authors: Anastasia Zabaniotou Katerina Stamou Mediterranean ecosystems are threatened by water and nutrient scarcity and continuous loss of soil organic carbon. Urban agglomerations and rural ecosystems in the Mediterranean region and globally are...
Fri May 22, 2020 03:00
Atmosphere, Vol. 11, Pages 540: Bio-Aerosols Negatively Affect Prochlorococcus in Oligotrophic Aerosol-Rich Marine Regions Atmosphere doi: 10.3390/atmos11050540 Authors: Eyal Rahav Adina Paytan Esra Mescioglu Edo Bar-Zeev Francisca Martínez Ruiz Peng Xian Barak Herut The marine cyanobacterium Prochlorococcus is a dominant photoautotroph in many oligotrophic Low-Nutrients-Low-Chlorophyll (LNLC) regions. While the chemical impact of aerosols upon interaction with surface...
Fri May 22, 2020 03:00
Atmosphere, Vol. 11, Pages 538: Predictability of the Strong Ural blocking Event in January 2012 in the Subseasonal to Seasonal Models of Europe and Canada Atmosphere doi: 10.3390/atmos11050538 Authors: Dong Chen Shaobo Qiao Shankai Tang Ho Nam Cheung Jieyu Liu Guolin Feng The occurrence of a Ural blocking (UB) event is an important precursor of severe cold air outbreaks in Siberia and East Asia, and thus is significant to accurately predict UB events. Using subseasonal...
Fri May 22, 2020 03:00
Bioengineering, Vol. 7, Pages 46: A Temperature-Controlled Patch Clamp Platform Demonstrated on Jurkat T Lymphocytes and Human Induced Pluripotent Stem Cell-Derived Neurons Bioengineering doi: 10.3390/bioengineering7020046 Authors: Jann Harberts Max Kusch John O’Sullivan Robert Zierold Robert H. Blick Though patch clamping at room temperature is a widely disseminated standard procedure in the electrophysiological community, it does not represent the biological system in mammals...
Fri May 22, 2020 03:00
Biology, Vol. 9, Pages 110: In Silico Identification of Type III PKS Chalcone and Stilbene Synthase Homologs in Marine Photosynthetic Organisms Biology doi: 10.3390/biology9050110 Authors: Daniele De De Luca Chiara Lauritano Marine microalgae are photosynthetic microorganisms at the base of the marine food webs. They are characterized by huge taxonomic and metabolic diversity and several species have been shown to have bioactivities useful for the treatment of human pathologies. However,...
Fri May 22, 2020 03:00
Biomedicines, Vol. 8, Pages 132: Brassicasterol with Dual Anti-Infective Properties against HSV-1 and Mycobacterium tuberculosis, and Cardiovascular Protective Effect: Nonclinical In Vitro and In Silico Assessments Biomedicines doi: 10.3390/biomedicines8050132 Authors: Sherif T. S. Hassan While few studies have revealed the biological properties of brassicasterol, a phytosterol, against some biological and molecular targets, it is believed that there are still many activities yet to...
Sun May 24, 2020 03:00
Biomedicines, Vol. 8, Pages 133: Evaluation of Aptamers as Affinity Reagents for an Enhancement of SRM-Based Detection of Low-Abundance Proteins in Blood Plasma Biomedicines doi: 10.3390/biomedicines8050133 Authors: Radko Ptitsyn Novikova Kiseleva Moysa Kurbatov Mannanova Zgoda Ponomarenko Lisitsa Archakov Selected reaction monitoring (SRM) is a mass spectrometric technique characterized by the exceptionally high selectivity and sensitivity of...
Sun May 24, 2020 03:00
Biomedicines, Vol. 8, Pages 131: When Less Is More: Specific Capture and Analysis of Tumor Exosomes in Plasma Increases the Sensitivity of Liquid Biopsy for Comprehensive Detection of Multiple Androgen Receptor Phenotypes in Advanced Prostate Cancer Patients Biomedicines doi: 10.3390/biomedicines8050131 Authors: Chiara Foroni Natasa Zarovni Laura Bianciardi Simona Bernardi Luca Triggiani Davide Zocco Marta Venturella Antonio Chiesi Francesca Valcamonico Alfredo Berruti...
Fri May 22, 2020 03:00
Biomedicines, Vol. 8, Pages 130: Spinal Cord Involvement in MS and Other Demyelinating Diseases Biomedicines doi: 10.3390/biomedicines8050130 Authors: Mariano Marrodan María I. Gaitán Jorge Correale Diagnostic accuracy is poor in demyelinating myelopathies, and therefore a challenge for neurologists in daily practice, mainly because of the multiple underlying pathophysiologic mechanisms involved in each subtype. A systematic diagnostic approach combining data from the clinical...
Fri May 22, 2020 03:00
Biomimetics, Vol. 5, Pages 23: Evo-Devo Strategies for Generative Architecture: Colour-Based Patterns in Polygon Meshes Biomimetics doi: 10.3390/biomimetics5020023 Authors: Diego Navarro-Mateu Ana Cocho-Bermejo Parametric design in architecture is often pigeonholed by its own definition and computational complexity. This article explores the generative capacity to integrate patterns and flows analogous to evolutionary developmental biology (Evo-Devo) strategies to develop emergent...
Fri May 22, 2020 03:00
Biomolecules, Vol. 10, Pages 807: ATBF1 Participates in Dual Functions of TGF-β via Regulation of Gene Expression and Protein Translocalization Biomolecules doi: 10.3390/biom10050807 Authors: Li Zhang Zheng Li Zhao TGF-β is a critical cytokine to regulate multiple pathophysiological functions. For tumor development and progression, TGF-β was reported to play dual functions as a tumor suppressor and epithelial-mesenchymal transition (EMT) inducer. The...
Sun May 24, 2020 03:00
Biomolecules, Vol. 10, Pages 805: Viridistratins A−C, Antimicrobial and Cytotoxic Benzo[j]fluoranthenes from Stromata of Annulohypoxylon viridistratum (Hypoxylaceae, Ascomycota) Biomolecules doi: 10.3390/biom10050805 Authors: Becker Wessel Luangsa-ard Stadler During the course of our search for novel biologically active metabolites from tropical fungi, we are using chemotaxonomic and taxonomic methodology for the preselection of interesting materials. Recently, three previously...
Sat May 23, 2020 03:00
Biomolecules, Vol. 10, Pages 806: Enhanced Biomass Yield of and Saccharification in Transgenic Tobacco Over-Expressing β-Glucosidase Biomolecules doi: 10.3390/biom10050806 Authors: Eun Jin Cho Quynh Anh Nguyen Yoon Gyo Lee Younho Song Bok Jae Park Hyeun-Jong Bae Here, we report an increase in biomass yield and saccharification in transgenic tobacco plants (Nicotiana tabacum L.) overexpressing thermostable β-glucosidase from Thermotoga maritima, BglB, targeted...
Sat May 23, 2020 03:00
Biomolecules, Vol. 10, Pages 803: Hemp (Cannabis sativa L.) Protein Hydrolysates Promote Anti-Inflammatory Response in Primary Human Monocytes Biomolecules doi: 10.3390/biom10050803 Authors: Noelia M Rodriguez-Martin Sergio Montserrat-de la Paz Rocio Toscano Elena Grao-Cruces Alvaro Villanueva Justo Pedroche Francisco Millan Maria C Millan-Linares Hemp seeds have a wide variety of chemical compounds which present biological activity. Specifically, the focus on proteins...
Fri May 22, 2020 03:00
Biomolecules, Vol. 10, Pages 804: Structure of O-Polysaccharide and Lipid A of Pantoea Agglomerans 8488 Biomolecules doi: 10.3390/biom10050804 Authors: Tetiana V. Bulyhina Evelina L. Zdorovenko Ludmila D. Varbanets Alexander S. Shashkov Alexandra A. Kadykova Yuriy A. Knirel Oleh V. Lushchak The Pantoea agglomerans 8488 lipopolysaccharide (LPS) was isolated, purified and characterized by monosaccharide and fatty acid analysis. The O-polysaccharide and lipid A components...
Fri May 22, 2020 03:00
Biomolecules, Vol. 10, Pages 801: Effects of Chronic Cannabidiol Treatment in the Rat Chronic Unpredictable Mild Stress Model of Depression Biomolecules doi: 10.3390/biom10050801 Authors: Zsolt Gáll Szidónia Farkas Ákos Albert Elek Ferencz Szende Vancea Melinda Urkon Melinda Kolcsár Several neuropharmacological actions of cannabidiol (CBD) due to the modulation of the endocannabinoid system as well as direct serotonergic and gamma-aminobutyric acidergic actions have...
Fri May 22, 2020 03:00
Biomolecules, Vol. 10, Pages 802: Effect of Erufosine on Membrane Lipid Order in Breast Cancer Cell Models Biomolecules doi: 10.3390/biom10050802 Authors: Rumiana Tzoneva Tihomira Stoyanova Annett Petrich Desislava Popova Veselina Uzunova Albena Momchilova Salvatore Chiantia Alkylphospholipids are a novel class of antineoplastic drugs showing remarkable therapeutic potential. Among them, erufosine (EPC3) is a promising drug for the treatment of several types of tumors....
Fri May 22, 2020 03:00
Biomolecules, Vol. 10, Pages 800: Amaryllidaceae Alkaloids of Belladine-Type from Narcissus pseudonarcissus cv. Carlton as New Selective Inhibitors of Butyrylcholinesterase Biomolecules doi: 10.3390/biom10050800 Authors: Abdullah Al Mamun Jana Maříková Daniela Hulcová Jiří Janoušek Marcela Šafratová Lucie Nováková Tomáš Kučera Martina Hrabinová Jiří Kuneš Jan Korábečný Lucie Cahlíková Thirteen known (1–12 and 16) and three previously undescribed...
Fri May 22, 2020 03:00
Brain Sciences, Vol. 10, Pages 318: Promoting the Social Inclusion of Children with ASD: A Family-Centred Intervention Brain Sciences doi: 10.3390/brainsci10050318 Authors: Roy McConkey Marie-Therese Cassin Rosie McNaughton The social isolation of children with autism spectrum disorder (ASD) is well documented. Their dearth of friends outside of the family and their lack of engagement in community activities places extra strains on the family. A project in Northern Ireland provided...
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Brain Sciences, Vol. 10, Pages 317: The Left Posterior Parietal Cortex Contributes to the Selection Process for the Initial Swing Leg in Gait Initiation Brain Sciences doi: 10.3390/brainsci10050317 Authors: Koichi Hiraoka Shintaro Gonno Ryota Inomoto The present study examined whether the left posterior parietal cortex contributes to the selection process for the initial swing leg in gait initiation. Healthy humans initiated the gait in response to an auditory start cue. Transcranial...
Fri May 22, 2020 03:00
Brain Sciences, Vol. 10, Pages 315: Liver Growth Factor Induces Glia-Associated Neuroprotection in an In Vitro Model of Parkinson´s Disease Brain Sciences doi: 10.3390/brainsci10050315 Authors: Rafael Gonzalo-Gobernado Diana Reimers María José Casarejos Lucía Calatrava Ferreras Manuela Vallejo-Muñoz Adriano Jiménez-Escrig Juan José Diaz-Gil Gonzalo M. Ulzurrun de Asanza Eulalia Bazán Parkinson’s disease is a neurodegenerative disorder characterized by...
Fri May 22, 2020 03:00
Brain Sciences, Vol. 10, Pages 314: Massive Data Management and Sharing Module for Connectome Reconstruction Brain Sciences doi: 10.3390/brainsci10050314 Authors: Jingbin Yuan Jing Zhang Lijun Shen Dandan Zhang Wenhuan Yu Hua Han Recently, with the rapid development of electron microscopy (EM) technology and the increasing demand of neuron circuit reconstruction, the scale of reconstruction data grows significantly. This brings many challenges, one of which is how to effectively...
Fri May 22, 2020 03:00
Brain Sciences, Vol. 10, Pages 313: Erratum: Pagonabarraga, J.; et al. A Spanish Consensus on the Use of Safinamide for Parkinson’s Disease in Clinical Practice. Brain Sci. 2020, 10, 176 Brain Sciences doi: 10.3390/brainsci10050313 Authors: Javier Pagonabarraga José Matías Arbelo Francisco Grandas Maria-Rosario Luquin Pablo Martínez Martín Maria Cruz Rodriguez-Oroz Francesc Valldeoriola Jaime Kulisevsky We would like to submit the following erratum to our recently...
Fri May 22, 2020 03:00
Brain Sciences, Vol. 10, Pages 316: Evaluation of Psychological Stress Parameters in Coronary Patients by Three Different Questionnaires as Pre-Requisite for Comprehensive Rehabilitation Brain Sciences doi: 10.3390/brainsci10050316 Authors: Ana Maria Pah Nicoleta Florina Buleu Anca Tudor Ruxandra Christodorescu Dana Velimirovici Stela Iurciuc Maria Rada Gheorghe Stoichescu-Hogea Marius Badalica-Petrescu Doina Georgescu Dorina Nutiu Mircea Iurciuc Simona...
Fri May 22, 2020 03:00
Cancers, Vol. 12, Pages 1342: MAT2A as Key Regulator and Therapeutic Target in MLLr Leukemogenesis Cancers doi: 10.3390/cancers12051342 Authors: Kathy-Ann Secker Bianca Bloechl Hildegard Keppeler Silke Duerr-Stoerzer Hannes Schmid Dominik Schneidawind Johan Jeong Thomas Hentrich Julia M. Schulze-Hentrich Corina Schneidawind Epigenetic dysregulation plays a pivotal role in mixed-lineage leukemia (MLL) pathogenesis, therefore serving as a suitable therapeutic...
Sun May 24, 2020 03:00
Cancers, Vol. 12, Pages 1341: Small Molecule KRAS Inhibitors: The Future for Targeted Pancreatic Cancer Therapy? Cancers doi: 10.3390/cancers12051341 Authors: Josef Gillson Yogambha Ramaswamy Gurvinder Singh Alemayehu A. Gorfe Nick Pavlakis Jaswinder Samra Anubhav Mittal Sumit Sahni Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest solid tumors in the world. Currently, there are no approved targeted therapies for PDAC. Mutations in Kirsten rat sarcoma...
Sun May 24, 2020 03:00
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